Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Hspa12b | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Hspa12b (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of HSPA12B mRNA | CTD | PMID:22206623 | Hspa12b | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of HSPA12B protein | CTD | PMID:31675489 | Hspa12b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Hspa12b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of HSPA12B mRNA | CTD | PMID:19933214 | Hspa12b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of HSPA12B mRNA | CTD | PMID:33387578 | Hspa12b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of HSPA12B mRNA | CTD | PMID:34747641 | Hspa12b | Rat | 2,4,6-tribromophenol | decreases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | 2,4,6-tribromophenol results in decreased expression of HSPA12B mRNA | CTD | PMID:31675489 | Hspa12b | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of HSPA12B protein | CTD | PMID:31675489 | Hspa12b | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Hspa12b (Mus musculus) | 6480464 | bisphenol S results in increased expression of HSPA12B mRNA | CTD | PMID:30951980 | Hspa12b | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Hspa12b (Mus musculus) | 6480464 | bisphenol S affects the methylation of HSPA12B gene | CTD | PMID:31683443 | Hspa12b | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of HSPA12B mRNA | CTD | PMID:22504374|PMID:25825206 | Hspa12b | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of HSPA12B mRNA | CTD | PMID:28959563 | Hspa12b | Rat | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of HSPA12B mRNA | CTD | PMID:20488242 | Hspa12b | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of HSPA12B mRNA | CTD | PMID:35163327 | Hspa12b | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of HSPA12B mRNA | CTD | PMID:30047161 | Hspa12b | Rat | antirheumatic drug | increases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of HSPA12B mRNA | CTD | PMID:24449571 | Hspa12b | Rat | aristolochic acid A | increases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of HSPA12B mRNA | CTD | PMID:33212167 | Hspa12b | Rat | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of HSPA12B mRNA | CTD | PMID:36841081 | Hspa12b | Rat | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of HSPA12B mRNA | CTD | PMID:21839799 | Hspa12b | Rat | benzo[a]pyrene | increases methylation | ISO | HSPA12B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of HSPA12B 3' UTR; Benzo(a)pyrene results in increased methylation of more ... | CTD | PMID:27901495 | Hspa12b | Rat | benzo[a]pyrene | affects methylation | ISO | HSPA12B (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of HSPA12B 5' UTR | CTD | PMID:27901495 | Hspa12b | Rat | benzo[a]pyrene | increases expression | ISO | Hspa12b (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of HSPA12B mRNA | CTD | PMID:32417428 | Hspa12b | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Hspa12b (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of HSPA12B mRNA | CTD | PMID:34319233 | Hspa12b | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of HSPA12B mRNA | CTD | PMID:25181051|PMID:34947998 | Hspa12b | Rat | bisphenol A | increases expression | ISO | Hspa12b (Mus musculus) | 6480464 | bisphenol A results in increased expression of HSPA12B mRNA | CTD | PMID:30951980|PMID:32156529 | Hspa12b | Rat | bisphenol F | increases expression | ISO | Hspa12b (Mus musculus) | 6480464 | bisphenol F results in increased expression of HSPA12B mRNA | CTD | PMID:30951980 | Hspa12b | Rat | Butylbenzyl phthalate | increases methylation | ISO | Hspa12b (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of HSPA12B intron | CTD | PMID:28392331 | Hspa12b | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of HSPA12B mRNA | CTD | PMID:19167457 | Hspa12b | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of HSPA12B mRNA | CTD | PMID:33453195 | Hspa12b | Rat | cantharidin | decreases expression | ISO | Hspa12b (Mus musculus) | 6480464 | Cantharidin results in decreased expression of HSPA12B mRNA | CTD | PMID:36907384 | Hspa12b | Rat | carbon nanotube | decreases expression | ISO | Hspa12b (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of HSPA12B mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681|PMID:25620056 | Hspa12b | Rat | dexamethasone | multiple interactions | ISO | Hspa12b (Mus musculus) | 6480464 | Dexamethasone inhibits the reaction [Lipopolysaccharides results in decreased expression of HSPA12B mRNA]; Dexamethasone inhibits the more ... | CTD | PMID:38901789 | Hspa12b | Rat | dexmedetomidine | multiple interactions | ISO | Hspa12b (Mus musculus) | 6480464 | Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in decreased expression of HSPA12B mRNA]; Dexmedetomidine inhibits the more ... | CTD | PMID:38901789 | Hspa12b | Rat | dioxygen | multiple interactions | ISO | Hspa12b (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of HSPA12B mRNA | CTD | PMID:30529165 | Hspa12b | Rat | dorsomorphin | multiple interactions | ISO | HSPA12B (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Hspa12b | Rat | entinostat | multiple interactions | ISO | HSPA12B (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Hspa12b | Rat | entinostat | increases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | entinostat results in increased expression of HSPA12B mRNA | CTD | PMID:26272509|PMID:27188386 | Hspa12b | Rat | ethylparaben | decreases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of HSPA12B mRNA | CTD | PMID:37690743 | Hspa12b | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of HSPA12B mRNA | CTD | PMID:30307764 | Hspa12b | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of HSPA12B mRNA | CTD | PMID:27387713 | Hspa12b | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of HSPA12B mRNA | CTD | PMID:22061828|PMID:33387578 | Hspa12b | Rat | glycidol | increases expression | EXP | | 6480464 | glycidol results in increased expression of HSPA12B mRNA | CTD | PMID:24915197 | Hspa12b | Rat | lipopolysaccharide | decreases expression | ISO | Hspa12b (Mus musculus) | 6480464 | Lipopolysaccharides results in decreased expression of HSPA12B mRNA | CTD | PMID:38901789 | Hspa12b | Rat | lipopolysaccharide | multiple interactions | ISO | Hspa12b (Mus musculus) | 6480464 | Dexamethasone inhibits the reaction [Lipopolysaccharides results in decreased expression of HSPA12B mRNA]; Dexamethasone inhibits the more ... | CTD | PMID:38901789 | Hspa12b | Rat | methamphetamine | multiple interactions | EXP | | 6480464 | SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of HSPA12B mRNA] | CTD | PMID:19564919 | Hspa12b | Rat | methamphetamine | increases expression | ISO | Hspa12b (Mus musculus) | 6480464 | Methamphetamine results in increased expression of HSPA12B mRNA | CTD | PMID:26307267 | Hspa12b | Rat | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of HSPA12B mRNA | CTD | PMID:19564919 | Hspa12b | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of HSPA12B mRNA | CTD | PMID:22504374|PMID:30047161 | Hspa12b | Rat | ozone | multiple interactions | ISO | Hspa12b (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Hspa12b | Rat | paracetamol | decreases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of HSPA12B mRNA | CTD | PMID:22230336 | Hspa12b | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of HSPA12B mRNA | CTD | PMID:33387578 | Hspa12b | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of HSPA12B mRNA | CTD | PMID:35163327 | Hspa12b | Rat | pioglitazone | multiple interactions | ISO | Hspa12b (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HSPA12B mRNA | CTD | PMID:27935865 | Hspa12b | Rat | rotenone | decreases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | Rotenone results in decreased expression of HSPA12B mRNA | CTD | PMID:29955902 | Hspa12b | Rat | SB 431542 | multiple interactions | ISO | HSPA12B (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Hspa12b | Rat | SCH 23390 | multiple interactions | EXP | | 6480464 | SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of HSPA12B mRNA] | CTD | PMID:19564919 | Hspa12b | Rat | silicon dioxide | increases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of HSPA12B mRNA | CTD | PMID:25895662 | Hspa12b | Rat | silver(1+) nitrate | increases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | Silver Nitrate analog results in increased expression of HSPA12B mRNA | CTD | PMID:22831968 | Hspa12b | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of HSPA12B mRNA | CTD | PMID:19281266 | Hspa12b | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of HSPA12B mRNA | CTD | PMID:30047161 | Hspa12b | Rat | titanium dioxide | decreases expression | ISO | Hspa12b (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of HSPA12B mRNA | CTD | PMID:23557971 | Hspa12b | Rat | urethane | decreases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | Urethane results in decreased expression of HSPA12B mRNA | CTD | PMID:28818685 | Hspa12b | Rat | valproic acid | increases expression | ISO | HSPA12B (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of HSPA12B mRNA | CTD | PMID:28001369 | Hspa12b | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of HSPA12B mRNA | CTD | PMID:20566332 | Hspa12b | Rat | vinclozolin | decreases methylation | EXP | | 6480464 | vinclozolin results in decreased methylation of HSPA12B gene | CTD | PMID:31682807 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















