Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Derl1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Derl1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DERL1 mRNA | CTD | PMID:22206623 | Derl1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Derl1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of DERL1 mRNA | CTD | PMID:22206623 | Derl1 | Rat | 17beta-estradiol | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of DERL1 mRNA | CTD | PMID:19167446 | Derl1 | Rat | 1H-pyrazole | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | pyrazole results in increased expression of DERL1 mRNA | CTD | PMID:17945193 | Derl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Derl1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of DERL1 mRNA; Tetrachlorodibenzodioxin promotes more ... | CTD | PMID:16214954|PMID:21762485 | Derl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DERL1 mRNA | CTD | PMID:18796159|PMID:21215274|PMID:27136898 | Derl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Derl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DERL1 mRNA | CTD | PMID:21570461|PMID:24680724 | Derl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DERL1 mRNA | CTD | PMID:18796159 | Derl1 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DERL1 mRNA | CTD | PMID:30851411 | Derl1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of DERL1 protein | CTD | PMID:34186270 | Derl1 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Derl1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of DERL1 mRNA | CTD | PMID:28973697 | Derl1 | Rat | 4-phenylbutyric acid | multiple interactions | EXP | | 6480464 | 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DERL1 protein] | CTD | PMID:30980806 | Derl1 | Rat | aflatoxin B1 | decreases expression | ISO | Derl1 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of DERL1 mRNA | CTD | PMID:19770486 | Derl1 | Rat | aflatoxin B1 | increases mutagenesis | EXP | | 6480464 | Aflatoxin B1 results in increased mutagenesis of DERL1 gene | CTD | PMID:36908029 | Derl1 | Rat | all-trans-retinoic acid | decreases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DERL1 mRNA | CTD | PMID:23724009 | Derl1 | Rat | all-trans-retinoic acid | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of DERL1 mRNA | CTD | PMID:33167477 | Derl1 | Rat | arsenous acid | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of DERL1 mRNA | CTD | PMID:35676786 | Derl1 | Rat | benzo[a]pyrene | affects methylation | ISO | DERL1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of DERL1 promoter | CTD | PMID:27901495 | Derl1 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | DERL1 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of DERL1 mRNA | CTD | PMID:19150397|PMID:20018196 | Derl1 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of DERL1 mRNA | CTD | PMID:33754040 | Derl1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DERL1 mRNA | CTD | PMID:25181051|PMID:34947998|PMID:41034487 | Derl1 | Rat | bisphenol A | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of DERL1 protein | CTD | PMID:34186270 | Derl1 | Rat | bisphenol A | decreases expression | ISO | DERL1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of DERL1 protein | CTD | PMID:33376534 | Derl1 | Rat | bisphenol A | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of DERL1 mRNA | CTD | PMID:33221593|PMID:40036665 | Derl1 | Rat | bisphenol AF | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of DERL1 protein | CTD | PMID:34186270 | Derl1 | Rat | Bisphenol B | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of DERL1 protein | CTD | PMID:34186270 | Derl1 | Rat | bisphenol F | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of DERL1 protein | CTD | PMID:34186270 | Derl1 | Rat | Butylbenzyl phthalate | affects methylation | ISO | Derl1 (Mus musculus) | 6480464 | butylbenzyl phthalate affects the methylation of DERL1 intron | CTD | PMID:28392331 | Derl1 | Rat | carbon nanotube | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of DERL1 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681|PMID:25620056 | Derl1 | Rat | CGP 52608 | multiple interactions | ISO | DERL1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DERL1 gene] | CTD | PMID:28238834 | Derl1 | Rat | clobetasol | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Clobetasol results in increased expression of DERL1 mRNA | CTD | PMID:27462272 | Derl1 | Rat | crocidolite asbestos | decreases expression | ISO | Derl1 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of DERL1 mRNA | CTD | PMID:29279043 | Derl1 | Rat | curcumin | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Curcumin results in increased expression of DERL1 mRNA | CTD | PMID:38229314 | Derl1 | Rat | cyclosporin A | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of DERL1 mRNA | CTD | PMID:25270620 | Derl1 | Rat | cyclosporin A | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DERL1 mRNA | CTD | PMID:20106945|PMID:25562108|PMID:27989131 | Derl1 | Rat | diarsenic trioxide | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of DERL1 mRNA | CTD | PMID:35676786 | Derl1 | Rat | diclofenac | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Diclofenac results in increased expression of DERL1 mRNA | CTD | PMID:26934552 | Derl1 | Rat | doxorubicin | decreases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of DERL1 mRNA | CTD | PMID:29803840 | Derl1 | Rat | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of DERL1 mRNA | CTD | PMID:30261314 | Derl1 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of DERL1 mRNA | CTD | PMID:31464424 | Derl1 | Rat | folic acid | multiple interactions | ISO | Derl1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DERL1 mRNA | CTD | PMID:22206623 | Derl1 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of DERL1 mRNA | CTD | PMID:24136188 | Derl1 | Rat | hexadecanoic acid | multiple interactions | ISO | DERL1 (Homo sapiens) | 6480464 | [Palmitic Acid co-treated with Oleic Acid] affects the expression of DERL1 mRNA | CTD | PMID:30547786 | Derl1 | Rat | isoniazide | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Isoniazid results in increased expression of DERL1 protein | CTD | PMID:40015660 | Derl1 | Rat | ivermectin | decreases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DERL1 protein | CTD | PMID:32959892 | Derl1 | Rat | lead(0) | affects splicing | ISO | DERL1 (Homo sapiens) | 6480464 | Lead affects the splicing of DERL1 mRNA | CTD | PMID:28903495 | Derl1 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of DERL1 mRNA | CTD | PMID:30467583 | Derl1 | Rat | methidathion | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | methidathion results in increased expression of DERL1 mRNA | CTD | PMID:34813904 | Derl1 | Rat | methylmercury chloride | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of DERL1 mRNA | CTD | PMID:28001369 | Derl1 | Rat | N-methyl-4-phenylpyridinium | decreases expression | ISO | Derl1 (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of DERL1 protein | CTD | PMID:26558463 | Derl1 | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of DERL1 mRNA | CTD | PMID:24136188 | Derl1 | Rat | nitrates | multiple interactions | ISO | Derl1 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of DERL1 more ... | CTD | PMID:35964746 | Derl1 | Rat | oleic acid | multiple interactions | ISO | DERL1 (Homo sapiens) | 6480464 | [Palmitic Acid co-treated with Oleic Acid] affects the expression of DERL1 mRNA | CTD | PMID:30547786 | Derl1 | Rat | paracetamol | affects expression | ISO | Derl1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of DERL1 mRNA | CTD | PMID:17562736 | Derl1 | Rat | pentachlorophenol | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of DERL1 mRNA | CTD | PMID:23892564 | Derl1 | Rat | phenobarbital | affects expression | ISO | Derl1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of DERL1 mRNA | CTD | PMID:23091169 | Derl1 | Rat | pirinixic acid | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of DERL1 mRNA | CTD | PMID:17426115 | Derl1 | Rat | rac-lactic acid | decreases expression | ISO | DERL1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DERL1 mRNA | CTD | PMID:30851411 | Derl1 | Rat | resveratrol | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | resveratrol results in increased expression of DERL1 protein | CTD | PMID:25505154 | Derl1 | Rat | silver atom | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Silver results in increased expression of DERL1 mRNA | CTD | PMID:27131904 | Derl1 | Rat | silver(0) | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Silver results in increased expression of DERL1 mRNA | CTD | PMID:27131904 | Derl1 | Rat | sodium arsenite | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of DERL1 mRNA | CTD | PMID:38568856 | Derl1 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of DERL1 mRNA | CTD | PMID:19281266 | Derl1 | Rat | streptozocin | multiple interactions | EXP | | 6480464 | 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DERL1 protein] | CTD | PMID:30980806 | Derl1 | Rat | streptozocin | increases expression | EXP | | 6480464 | Streptozocin results in increased expression of DERL1 protein | CTD | PMID:30980806 | Derl1 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | Derl1 (Mus musculus) | 6480464 | tert-Butylhydroperoxide results in decreased expression of DERL1 mRNA | CTD | PMID:15003993 | Derl1 | Rat | tetrachloromethane | increases expression | ISO | Derl1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of DERL1 mRNA | CTD | PMID:27339419|PMID:31919559 | Derl1 | Rat | titanium dioxide | increases methylation | ISO | Derl1 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of DERL1 gene | CTD | PMID:35295148 | Derl1 | Rat | titanium dioxide | decreases methylation | ISO | Derl1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of DERL1 gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Derl1 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of DERL1 mRNA | CTD | PMID:19015723 | Derl1 | Rat | zebularine | increases expression | ISO | DERL1 (Homo sapiens) | 6480464 | pyrimidin-2-one beta-ribofuranoside results in increased expression of DERL1 mRNA | CTD | PMID:19194470 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















