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Gene: Rasal1 (RAS protein activator like 1) Rattus norvegicus

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Symbol:

Rasal1

Name:

RAS protein activator like 1

RGD ID:

1311820

Description:

Predicted to enable GTPase activator activity. Predicted to be involved in positive regulation of dendrite extension and regulation of intracellular signal transduction. Predicted to be located in cytosol and plasma membrane. Orthologous to human RASAL1 (RAS protein activator like 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC360814; RAS protein activator like 1 (GAP1 like); rasGAP-activating-like protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RASAL1 (RAS protein activator like 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Rasal1 (RAS protein activator like 1 (GAP1 like))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rasal1 (RAS protein activator like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RASAL1 (RAS protein activator like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RASAL1 (RAS protein activator like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rasal1 (RAS protein activator like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RASAL1 (RAS protein activator like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RASAL1 (RAS protein activator like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rasal1 (RAS protein activator like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rasal1 (RAS protein activator like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RASAL1 (RAS protein activator like 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rasal1 (RAS protein activator like 1 (GAP1 like))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gap-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rasal1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	41,541,865 - 41,574,957 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	41,541,865 - 41,574,315 (-)	Ensembl				GRCr8
mRatBN7.2	12	35,881,269 - 35,913,727 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	35,881,270 - 35,913,727 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	37,060,900 - 37,093,354 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	37,672,113 - 37,704,566 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	36,724,584 - 36,757,037 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	12	42,820,176 - 42,852,595 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	12	42,736,514 - 42,769,064 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	12	41,610,247 - 41,642,662 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	12	52,061,824 - 52,094,242 (-)	NCBI		F344_StmMcwi
Rnor_6.0	12	41,416,218 - 41,449,445 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	41,416,218 - 41,448,668 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	43,274,639 - 43,307,356 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	37,047,909 - 37,080,129 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	37,542,753 - 37,575,150 (-)	NCBI		Celera
RGSC_v3.1	12	36,911,885 - 36,943,519 (-)	NCBI
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hereditary Neoplastic Syndromes (ISO)

kidney disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3-chloropropane-1,2-diol (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (EXP)

6-propyl-2-thiouracil (EXP)

actinomycin D (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

alpha-Zearalanol (EXP)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

buta-1,3-diene (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

camptothecin (ISO)

carbon nanotube (ISO)

choline (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clofibrate (ISO)

Cuprizon (EXP)

DDE (ISO)

dexamethasone (ISO)

dibutyl phthalate (EXP,ISO)

diethylstilbestrol (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

genistein (ISO)

gentamycin (EXP)

indometacin (ISO)

inulin (ISO)

isotretinoin (ISO)

L-methionine (ISO)

lipopolysaccharide (ISO)

methamphetamine (ISO)

methapyrilene (ISO)

mono(2-ethylhexyl) phthalate (ISO)

Nutlin-3 (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

pentanal (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

pregnenolone 16alpha-carbonitrile (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

Soman (EXP)

tamoxifen (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

triclosan (ISO)

triptonide (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to calcium ion (IEA)

intracellular signal transduction (IEA)

negative regulation of Ras protein signal transduction (IEA)

positive regulation of dendrite extension (IEA,ISO)

regulation of intracellular signal transduction (IBA)

Cellular Component

cytosol (IEA,ISO)

plasma membrane (IEA,ISO)

Molecular Function

GTPase activator activity (IBA,IEA)

metal ion binding (IEA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:16009725	PMID:22056649	PMID:23999003	PMID:27396351

Genomics

Comparative Map Data

Rasal1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	41,541,865 - 41,574,957 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	41,541,865 - 41,574,315 (-)	Ensembl				GRCr8
mRatBN7.2	12	35,881,269 - 35,913,727 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	35,881,270 - 35,913,727 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	37,060,900 - 37,093,354 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	37,672,113 - 37,704,566 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	36,724,584 - 36,757,037 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	12	42,820,176 - 42,852,595 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	12	42,736,514 - 42,769,064 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	12	41,610,247 - 41,642,662 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	12	52,061,824 - 52,094,242 (-)	NCBI		F344_StmMcwi
Rnor_6.0	12	41,416,218 - 41,449,445 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	41,416,218 - 41,448,668 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	43,274,639 - 43,307,356 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	37,047,909 - 37,080,129 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	37,542,753 - 37,575,150 (-)	NCBI		Celera
RGSC_v3.1	12	36,911,885 - 36,943,519 (-)	NCBI
Cytogenetic Map	12	q16	NCBI

RASAL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	113,099,278 - 113,136,756 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	113,096,517 - 113,136,258 (-)	Ensembl			hg38	GRCh38
GRCh37	12	113,537,083 - 113,574,044 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	112,021,701 - 112,058,404 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	112,000,037 - 112,036,741	NCBI
Celera	12	113,163,615 - 113,201,034 (-)	NCBI		Celera
Cytogenetic Map	12	q24.13	NCBI
HuRef	12	110,549,290 - 110,586,742 (-)	NCBI		HuRef
CHM1_1	12	113,504,941 - 113,542,306 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	113,075,920 - 113,113,399 (-)	NCBI		T2T-CHM13v2.0

Rasal1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	120,786,105 - 120,817,662 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	120,786,877 - 120,817,662 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	120,648,040 - 120,679,597 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	120,648,812 - 120,679,597 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	121,098,831 - 121,129,602 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	120,909,439 - 120,940,210 (+)	NCBI		MGSCv36	mm8
Celera	5	117,733,997 - 117,765,218 (+)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	60.63	NCBI

Rasal1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	9,447,984 - 9,472,453 (-)	Ensembl
ChiLan1.0	NW_004955482	9,447,984 - 9,471,852 (-)	NCBI	ChiLan1.0	ChiLan1.0

RASAL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	121,188,448 - 121,224,450 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	121,181,843 - 121,220,847 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	110,703,420 - 110,741,025 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	114,087,715 - 114,124,540 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	114,087,715 - 114,124,540 (-)	Ensembl			panPan2	panpan1.1

RASAL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	10,503,309 - 10,532,217 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	10,504,236 - 10,533,071 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	10,623,675 - 10,653,746 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	10,745,717 - 10,775,853 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	10,745,767 - 10,775,843 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	10,719,225 - 10,749,519 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	10,782,407 - 10,812,352 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	10,831,027 - 10,861,100 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rasal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	148,523,195 - 148,547,441 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936668	3,022,084 - 3,045,578 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936668	3,022,088 - 3,045,817 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RASAL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	38,601,394 - 38,633,425 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	38,598,901 - 38,633,190 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	41,059,508 - 41,092,592 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RASAL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	108,344,753 - 108,385,009 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	108,342,809 - 108,384,530 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	136,711,942 - 136,748,914 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rasal1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	19,296,259 - 19,320,595 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	19,297,008 - 19,320,968 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rasal1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	33,145,928 - 33,178,347 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rasal1
150 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	287
Count of miRNA genes:	167
Interacting mature miRNAs:	186
Transcripts:	ENSRNOT00000001856
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	29775522	42298555	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1556747	Calcic1	Intracellular calcium level QTL 1		3.6	platelet calcium amount (VT:0010500)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
631829	Alc6	Alcohol consumption QTL 6	4.7		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	34243475	43352593	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat

Markers in Region

RH137453

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	35,881,458 - 35,881,665 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	41,416,407 - 41,416,613	NCBI	Rnor6.0
Rnor_5.0	12	43,274,828 - 43,275,034	UniSTS	Rnor5.0
RGSC_v3.4	12	37,048,098 - 37,048,304	UniSTS	RGSC3.4
Celera	12	37,542,942 - 37,543,148	UniSTS
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	14	12	115	224	81	80	55	139	49	22	439	297	11	197	81	92	31	11	11

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089599	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001856 ⟹ ENSRNOP00000001856

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	41,541,865 - 41,574,315 (-)	Ensembl
mRatBN7.2 Ensembl	12	35,881,270 - 35,913,727 (-)	Ensembl
Rnor_6.0 Ensembl	12	41,416,218 - 41,448,668 (-)	Ensembl

RefSeq Acc Id:

NM_001108335 ⟹ NP_001101805

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	41,541,865 - 41,574,315 (-)	NCBI
mRatBN7.2	12	35,881,270 - 35,913,727 (-)	NCBI
Dahl_SR_JrHsd	12	42,820,176 - 42,852,595 (-)	NCBI
Lyon_Normotensive	12	42,736,514 - 42,769,064 (-)	NCBI
Lyon_Hypertensive	12	41,610,247 - 41,642,662 (-)	NCBI
F344_StmMcwi	12	52,061,824 - 52,094,242 (-)	NCBI
Rnor_6.0	12	41,416,218 - 41,448,668 (-)	NCBI
Rnor_5.0	12	43,274,639 - 43,307,356 (-)	NCBI
RGSC_v3.4	12	37,047,909 - 37,080,129 (-)	RGD
Celera	12	37,542,753 - 37,575,150 (-)	RGD

Sequence:

show sequence

GAAGAGACGATGCAAGGGGATGTTCGAGCTCCCTCCCTCCACTCGCATCAGACCCCCAGGGAGC
GTGCGCCGCCTGCCGCCCAGCGAGACCCTGCATCCAGCCCACTCGCACCCCAGACCCGTACCTG
TGGGAACCCGTGGACTGCGTGCTTGGCCCGCCGCTGATGACATGTAGGGTCACCTCCTGGTCCA
GCCTCGGAACCTCGGCAGACTCCTTGCCTGGAAAGTTTGGGACTGTGCGCCATGGCCAAGAGCG
GCTCTCTGAGTATCCGCGTGGTGGAGGGACGGGCGCTGCCCGCCAAGGACGTGTCTGGGAGCAG
TGACCCCTACTGTCTTGTGAAAGTGGATGATGAGGTGGTGGCCAGGACAGCAACCATCTGGAGG
AGCCTGAGCCCCTTTTGGGGGGAGGAGTACACTGTTCACCTTCCACTGGACTTCCACCACCTGG
CCTTCTACGTGCTGGATGAGGATACTGTTGGACACGACGACATCATTGGGAAGATCTCCTTGAG
CAAAGAGGCGATCACAGCGGACCCTCGAGGGATTGACAGCTGGATCAACCTGAGCCGAGTGGAT
CCAGATGAGGAAGTGCAGGGTGAGGTCTGCCTGGCTGTGAAGCTGCTGGAGGATGCTCGGGGGA
GATGCCTCCGCTGCCACGTGAGACAGGCCAGGGACCTGGCCCCTCGGGACATCTCTGGCACATC
GGACCCATTTGCCCGTGTGTTCTGGGGCAGCCGTAGTTTGGAAACTTCGACCATCAAGAAGACC
CGATTCCCACATTGGGATGAGGTGCTGGAACTACGAGAGGCTCCGGGAACCACATCCCCGCTGC
GAGTGGAACTCTGGGATTGGGACATGGTGGGCAAAAATGACTTCCTGGGCATGGTGGAATTCAC
CCCACAGACCCTCCAGCAGAAGCCACCCAATGGCTGGTTCCGTCTCCTGCCTTTTCCTAGAGCT
GAGGATTCTGGGGGGAGCCTGGGTGCCCTGCGGCTGAAGGTGCGCCTCACTGAGGACCGGGTCC
TGCCTTCCCAGTACTACCAGCCTCTCATGGAACTGCTTCTGGAGTCCGTGCAAGGGCCAGCCGA
GGAGGACACCACCAGCCCCCTGGCATTGCTAGAGGAGTTGGCCTCTGGGGACTGTCGTCAGGAC
CTTGCCACCAAACTGGTGAAGCTTTTCCTGGGCCGGGGCCTGGCTGGGCCCTTTCTAGATTACC
TCACAAGGCGTGAGGTGGCACGAACCAATGACCCCAACACCCTCTTCCGTTCTAACTCCTTGGC
ATCCAAGTCGATGGAACAGTTCATGAAACTCGTGGGCATGCGCTACCTGCATGAGGTCCTGAGG
CCGGTGATCAGCCGCGTCTTCGAGGAGAAGAAATATATGGAGCTGGACCCTTCCAAGATGGACC
TGAACCGCTCCCGGAGAATCTCCTTCAAGGGCACACCCACGGAGGAGCAGGTGCGGGAGACCAG
CCTGGGGCTGCTGACCGGATACCTGGGGTCCGTTGTGGACGCCATCGTGAGCTCTGCCGGGCGC
TGCCCACTTGCCCTGCGCTTAGCCTTTAAGCAACTCCAGCAGTGTGTGGAGAAGCGCTTCCCTG
GGATGGAGCATCAGGACGTGAAGTACTTGGCCACTAGCGGCTTCCTCTTTCTGCGGTTCTTTGC
GCCCGCCATCCTCACACCGAAGCTGTTTGACCTCAGAGACCACCACGCAGACCCCCAGACCAGC
CGCTCCCTGCTGCTGCTTGCCAAGGCTGTGCAGAGCATTGGAAACCTGGGCCAGCAGCTGGGCC
AGGGCAAAGAGCAGTGGCTAGCCCCCCTCCATCCCTTCCTGCTGCAGAGCATCTCACGTGTGAG
GGACTTCCTGGACCAGCTGGTGGATGTGGATGGGGATGAGGAGGCTGGGGGATCAACCTGCGCC
CTGGTCCAACCCTCAACAATTGTTCGAGAAGGCTTTCTGCTGAAGCGCAAGGAGGAGCCTGCAA
GCCTGGCCACCCGCTTTGCCTTCAAGAAGCGCTACTTCCGACTGAGTGGGCGGGACCTCTCCTA
CTCTAAGACTCCTGAGTGGCAGGTTCACTCATCCATCCCGTTGTCCTGCATCCGGGCTGTGGAG
CGTGTGGATGAGGGTGCCTTCCAACTGCCACATGTCATGCAGGTGGTGACACAGGATGGCACCG
GGGCATCACACACCACCTACCTCCAGTGCAAGAACGTGAATGACCTCAATCAATGGCTGTCAGC
CCTGCGCAAAGCCAGCGCCCCCAACCCGGGCAAGCTGGCTGCTTGTCACCCTGGTGCCTTCCGC
AGCGGGCGCTGGACCTGCTGCCTCCAGGCCGAGCGCTCAGCTGTTGGCTGTAGCCGCACACACT
CAGCTGTCACGCTGGGAGACTGGAGTGACCCACTGGATCCTGACGCCGAAGCCCAGATGGTGTA
TCGCCAGCTGCTCCTGGGCCGAGACCAGCTCAGGCTGAAACTGCTGGAGGACTCCAGCCTGGAC
ACAGCTCCAGATGTGGACCCTGGGAAGGACTCCAGTGCTGTAGATGGGCCCTGTGCTGAGGTTC
TAGCCCAGCAGAGGGAGGCCACCACCCGTCTGCTGCAGGTACTTGAAGACTTGGAGCAAGCCCA
TGAGGAATTCCAGAAACGGGGCTAGGGGAAAGTGGCCCTCTAGGACACTGGATGCTGAGAAGGT
GCCAGAGCCAGTTGGGGACAGAGCCACGGGGCTTCCCTGAGCTTACTTTGGCCTAGGCATCTTC
ATTGTCGTGGCTTGGAGCCTCCCAAAGTGTGGTCCTGTGTGCCCTGTAGCCAGCCAGGGCATAG
GAACCTTTAAGAGGGCCCAGCCTTGTACCGACTGACCAAACCTCACTTCCTTCTCTGAGCCTGG
AGCCTCAGCTTCACTGGATACAGCTCCTCCAGTACCGGTGGAACCCATACCGGTGGCACCCATC
TCACCCCAAGCTGCTGGGTGCAGCTGTACCTGAACTCCAATCCTGGCTGATGCAGAAAAACACT
CAATATGCTTGACCAGGAACTTCCCGTGTTATCACTTCCGTGGGCCCCGGTGACCTCACAGATC
CTTCTGTACCCCACTTTCATCTGGCAGTCCCGGCCTCAAGCTTCTGGGACCCGGTGTTCTCGGA
AGAACGGACTGGGAGCCCAGCATGCCAATTTGGAGCCTCGAAGCTGGACACGGGCTCTTCCTCC
CTCCTATACCCTGTATAAAGTGACGTGTGAGCATGCTT

hide sequence

RefSeq Acc Id:

XM_006249395 ⟹ XP_006249457

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	41,541,868 - 41,574,957 (-)	NCBI
mRatBN7.2	12	35,881,269 - 35,913,356 (-)	NCBI
Rnor_6.0	12	41,416,220 - 41,449,445 (-)	NCBI
Rnor_5.0	12	43,274,639 - 43,307,356 (-)	NCBI

Sequence:

show sequence

CGAGGAGGAAGGTGCCAGCGTCTACCCTGGGACAAGCCTTCTGTTCACATGATCCCATTTGAAA
CTCGCAAACGCACAAAGCATCTTGGGAAGGGAGCAAAAGGGAAGAAGAGCTCTGTGTGAGGTGG
AAGGGCGTCCTGAAAGTCTTGCCAGGAGATGTGACATTTAAGACACACCTTGAAGAGGAAGAAG
AACAACAAAAATATCGAATCCTCTGTGGTTGGTTAGGTGTCTGCCACTGTTCTGAGACCCGTGT
GGGAGTATCTCATTTAATTCTCTCTAAACCCTGTGAATGAGACACGTGTCGCGCTCACTGAACA
GTTGAGAAAACTAAACGGAGGCACAGAGGTTAAGTGACTGACTCATTGAAGACCAGGCATTAGT
AAATCTACCAAATGGCAGAGTCAGAACTCAAACCCAGGGAGGAGCCTTCTGGCAAGTGACCCCC
ACCTCTCAGAACCCCAGTTTTTGTTGCGCGCGTGTCTGTGTTTGGTTGGTTTTTCGTTTTGTTT
GTTGTTTGGTTTTTAAATCCATAGGTGGAGGGCATGCATGACATAGAGTTGCTGAGGGCTCGAA
ACTGAGATAATCCCCATGAAAGGCTCAAGCGGTGCCTGGCACACGGTTAAGTGTTCGAGGATTG
CAGATGGTTCTTATCGTGTAGCCCCGGCGGTGTTATCTCCGCGCCTCCCCTCCCCCTGCGGCCG
CGGCTTCCTCCCCCGCAGTGGCAGCCGGTGACGTGGGAGCCTCCGCTGGCACACTCCGGGTTTA
ATTGGAGCCGAAGAGACGATGCAAGGGGATGTTCGAGCTCCCTCCCTCCACTCGCATCAGACCC
CCAGGGAGCGTGCGCCGCCTGCCGCCCAGCGAGAGTACTGTTCCGGGACCCCGAGGCTGGTGTT
GGGGTGGCAGGTGGCGGGGTGGGAGAGGTGCGGAGGTGCGGAGGTGCTGGGTTGAGGACAGGCA
GGAGACACCCAGGTTTTTGGAGGGCCCAATACCAGCTCAGTAACAGCCTGCCGCCCTGCCTGAC
TGCTCGCGCCTCCCCCACACCCACCCCCTGACCCATAGCGCCTGGGTGTCCCCGGCTGAGTGCA
GTGGTGTGGGGTGCCAGCAGGGGGCGCTCGCGTAGGGGCTCAGAGCGGGCGGGGCAGCTACGGG
GGGGCGGGATCGGGAGGGACCTCCCGGGCTGCAGACGCCAGGCTCAGCCTGCCCAGATCGCAGC
GCACAGCTACCTGTAGCTCTGGACGCATGTCCCCTTCCGGGACCCAGCACTTCTCCCTCCTAGC
CCTGCATCCAGCCCACTCGCACCCCAGACCCGTACCTGTGGGAACCCGTGGACTGCGTGCTTGG
CCCGCCGCTGATGACATGTAGGGTCACCTCCTGGTCCAGCCTCGGAACCTCGGCAGACTCCTTG
CCTGGAAAGTTTGGGACTGTGCGCCATGGCCAAGAGCGGCTCTCTGAGTATCCGCGTGGTGGAG
GGACGGGCGCTGCCCGCCAAGGACGTGTCTGGGAGCAGTGACCCCTACTGTCTTGTGAAAGTGG
ATGATGAGGTGGTGGCCAGGACAGCAACCATCTGGAGGAGCCTGAGCCCCTTTTGGGGGGAGGA
GTACACTGTTCACCTTCCACTGGACTTCCACCACCTGGCCTTCTACGTGCTGGATGAGGATACT
GTTGGACACGACGACATCATTGGGAAGATCTCCTTGAGCAAAGAGGCGATCACAGCGGACCCTC
GAGGGATTGACAGCTGGATCAACCTGAGCCGAGTGGATCCAGATGAGGAAGTGCAGGGTGAGGT
CTGCCTGGCTGTGAAGCTGCTGGAGGATGCTCGGGGGAGATGCCTCCGCTGCCACGTGAGACAG
GCCAGGGACCTGGCCCCTCGGGACATCTCTGGCACATCGGACCCATTTGCCCGTGTGTTCTGGG
GCAGCCGTAGTTTGGAAACTTCGACCATCAAGAAGACCCGATTCCCACATTGGGATGAGGTGCT
GGAACTACGAGAGGCTCCGGGAACCACATCCCCGCTGCGAGTGGAACTCTGGGATTGGGACATG
GTGGGCAAAAATGACTTCCTGGGCATGGTGGAATTCACCCCACAGACCCTCCAGCAGAAGCCAC
CCAATGGCTGGTTCCGTCTCCTGCCTTTTCCTAGAGCTGAGGATTCTGGGGGGAGCCTGGGTGC
CCTGCGGCTGAAGGTGCGCCTCACTGAGGACCGGGTCCTGCCTTCCCAGTACTACCAGCCTCTC
ATGGAACTGCTTCTGGAGTCCGTGCAAGGGCCAGCCGAGGAGGACACCACCAGCCCCCTGGCAT
TGCTAGAGGAGTTGGCCTCTGGGGACTGTCGTCAGGACCTTGCCACCAAACTGGTGAAGCTTTT
CCTGGGCCGGGGCCTGGCTGGGCCCTTTCTAGATTACCTCACAAGGCGTGAGGTGGCACGAACC
AATGACCCCAACACCCTCTTCCGTTCTAACTCCTTGGCATCCAAGTCGATGGAACAGTTCATGA
AACTCGTGGGCATGCGCTACCTGCATGAGGTCCTGAGGCCGGTGATCAGCCGCGTCTTCGAGGA
GAAGAAATATATGGAGCTGGACCCTTCCAAGATGGACCTGAACCGCTCCCGGAGAATCTCCTTC
AAGGGCACACCCACGGAGGAGCAGGTGCGGGAGACCAGCCTGGGGCTGCTGACCGGATACCTGG
GGTCCGTTGTGGACGCCATCGTGAGCTCTGCCGGGCGCTGCCCACTTGCCCTGCGCTTAGCCTT
TAAGCAACTCCAGCAGTGTGTGGAGAAGCGCTTCCCTGGGATGGAGCATCAGGACGTGAAGTAC
TTGGCCACTAGCGGCTTCCTCTTTCTGCGGTTCTTTGCGCCCGCCATCCTCACACCGAAGCTGT
TTGACCTCAGAGACCACCACGCAGACCCCCAGACCAGCCGCTCCCTGCTGCTGCTTGCCAAGGC
TGTGCAGAGCATTGGAAACCTGGGCCAGCAGCTGGGCCAGGGCAAAGAGCAGTGGCTAGCCCCC
CTCCATCCCTTCCTGCTGCAGAGCATCTCACGTGTGAGGGACTTCCTGGACCAGCTGGTGGATG
TGGATGGGGATGAGGAGGCTGGGGGATCAACCTGCGCCCTGGTCCAACCCTCAACAATTGTTCG
AGAAGGCTTTCTGCTGAAGCGCAAGGAGGAGCCTGCAAGCCTGGCCACCCGCTTTGCCTTCAAG
AAGCGCTACTTCCGACTGAGTGGGCGGGACCTCTCCTACTCTAAGACTCCTGAGTGGCAGGTTC
ACTCATCCATCCCGTTGTCCTGCATCCGGGCTGTGGAGCGTGTGGATGAGGGTGCCTTCCAACT
GCCACATGTCATGCAGGTGGTGACACAGGATGGCACCGGGGCATCACACACCACCTACCTCCAG
TGCAAGAACGTGAATGACCTCAATCAATGGCTGTCAGCCCTGCGCAAAGCCAGCGCCCCCAACC
CGGGCAAGCTGGCTGCTTGTCACCCTGGTGCCTTCCGCAGCGGGCGCTGGACCTGCTGCCTCCA
GGCCGAGCGCTCAGCTGTTGGCTGTAGCCGCACACACTCAGCTGTCACGCTGGGAGACTGGAGT
GACCCACTGGATCCTGACGCCGAAGCCCAGATGGTGTATCGCCAGCTGCTCCTGGGCCGAGACC
AGCTCAGGCTGAAACTGCTGGAGGACTCCAGCCTGGACACAGCTCCAGATGTGGACCCTGGGAA
GGACTCCAGTGCTGTAGATGGGCCCTGTGCTGAGGTTCTAGCCCAGCAGAGGGAGGCCACCACC
CGTCTGCTGCAGGTACTTGAAGACTTGGAGCAAGCCCATGAGGAATTCCAGAAACGGGGCTAGG
GGAAAGTGGCCCTCTAGGACACTGGATGCTGAGAAGGTGCCAGAGCCAGTTGGGGACAGAGCCA
CGGGGCTTCCCTGAGCTTACTTTGGCCTAGGCATCTTCATTGTCGTGGCTTGGAGCCTCCCAAA
GTGTGGTCCTGTGTGCCCTGTAGCCAGCCAGGGCATAGGAACCTTTAAGAGGGCCCAGCCTTGT
ACCGACTGACCAAACCTCACTTCCTTCTCTGAGCCTGGAGCCTCAGCTTCACTGGATACAGCTC
CTCCAGTACCGGTGGAACCCATACCGGTGGCACCCATCTCACCCCAAGCTGCTGGGTGCAGCTG
TACCTGAACTCCAATCCTGGCTGATGCAGAAAAACACTCAATATGCTTGACCAGGAACTTCCCG
TGTTATCACTTCCGTGGGCCCCGGTGACCTCACAGATCCTTCTGTACCCCACTTTCATCTGGCA
GTCCCGGCCTCAAGCTTCTGGGACCCGGTGTTCTCGGAAGAACGGACTGGGAGCCCAGCATGCC
AATTTGGAGCCTCGAAGCTGGACACGGGCTCTTCCTCCCTCCTATACCCTGTATAAAGTGACGT
GTGAGCATGC

hide sequence

RefSeq Acc Id:

XM_017598399 ⟹ XP_017453888

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	41,541,868 - 41,559,513 (-)	NCBI
mRatBN7.2	12	35,881,269 - 35,898,918 (-)	NCBI
Rnor_6.0	12	41,416,220 - 41,433,866 (-)	NCBI

Sequence:

show sequence

ATGAGGTGCTGGAACTACGAGAGGCTCCGGGAACCACATCCCCGCTGCGAGTGGAACTCTGGGA
TTGGGACATGGTGGGCAAAAATGACTTCCTGGGTGGAATTCACCCCACAGACCCTCCAGCAGAA
GCCACCCAATGGCTGGTTCCGTCTCCTGCCTTTTCCTAGAGCTGAGGATTCTGGGGGGAGCCTG
GGTGCCCTGCGGCTGAAGGTGCGCCTCACTGAGGACCGGGTCCTGCCTTCCCAGTACTACCAGC
CTCTCATGGAACTGCTTCTGGAGTCCGTGCAAGGGCCAGCCGAGGAGGACACCACCAGCCCCCT
GGCATTGCTAGAGGAGTTGGCCTCTGGGGACTGTCGTCAGGACCTTGCCACCAAACTGGTGAAG
CTTTTCCTGGGCCGGGGCCTGGCTGGGCCCTTTCTAGATTACCTCACAAGGCGTGAGGTGGCAC
GAACCAATGACCCCAACACCCTCTTCCGTTCTAACTCCTTGGCATCCAAGTCGATGGAACAGTT
CATGAAACTCGTGGGCATGCGCTACCTGCATGAGGTCCTGAGGCCGGTGATCAGCCGCGTCTTC
GAGGAGAAGAAATATATGGAGCTGGACCCTTCCAAGATGGACCTGAACCGCTCCCGGAGAATCT
CCTTCAAGGGCACACCCACGGAGGAGCAGGTGCGGGAGACCAGCCTGGGGCTGCTGACCGGATA
CCTGGGGTCCGTTGTGGACGCCATCGTGAGCTCTGCCGGGCGCTGCCCACTTGCCCTGCGCTTA
GCCTTTAAGCAACTCCAGCAGTGTGTGGAGAAGCGCTTCCCTGGGATGGAGCATCAGGACGTGA
AGTACTTGGCCACTAGCGGCTTCCTCTTTCTGCGGTTCTTTGCGCCCGCCATCCTCACACCGAA
GCTGTTTGACCTCAGAGACCACCACGCAGACCCCCAGACCAGCCGCTCCCTGCTGCTGCTTGCC
AAGGCTGTGCAGAGCATTGGAAACCTGGGCCAGCAGCTGGGCCAGGGCAAAGAGCAGTGGCTAG
CCCCCCTCCATCCCTTCCTGCTGCAGAGCATCTCACGTGTGAGGGACTTCCTGGACCAGCTGGT
GGATGTGGATGGGGATGAGGAGGCTGGGGGATCAACCTGCGCCCTGGTCCAACCCTCAACAATT
GTTCGAGAAGGCTTTCTGCTGAAGCGCAAGGAGGAGCCTGCAAGCCTGGCCACCCGCTTTGCCT
TCAAGAAGCGCTACTTCCGACTGAGTGGGCGGGACCTCTCCTACTCTAAGACTCCTGAGTGGCA
GGTTCACTCATCCATCCCGTTGTCCTGCATCCGGGCTGTGGAGCGTGTGGATGAGGGTGCCTTC
CAACTGCCACATGTCATGCAGGTGGTGACACAGGATGGCACCGGGGCATCACACACCACCTACC
TCCAGTGCAAGAACGTGAATGACCTCAATCAATGGCTGTCAGCCCTGCGCAAAGCCAGCGCCCC
CAACCCGGGCAAGCTGGCTGCTTGTCACCCTGGTGCCTTCCGCAGCGGGCGCTGGACCTGCTGC
CTCCAGGCCGAGCGCTCAGCTGTTGGCTGTAGCCGCACACACTCAGCTGTCACGCTGGGAGACT
GGAGTGACCCACTGGATCCTGACGCCGAAGCCCAGATGGTGTATCGCCAGCTGCTCCTGGGCCG
AGACCAGCTCAGGCTGAAACTGCTGGAGGACTCCAGCCTGGACACAGCTCCAGATGTGGACCCT
GGGAAGGACTCCAGTGCTGTAGATGGGCCCTGTGCTGAGGTTCTAGCCCAGCAGAGGGAGGCCA
CCACCCGTCTGCTGCAGGTACTTGAAGACTTGGAGCAAGCCCATGAGGAATTCCAGAAACGGGG
CTAGGGGAAAGTGGCCCTCTAGGACACTGGATGCTGAGAAGGTGCCAGAGCCAGTTGGGGACAG
AGCCACGGGGCTTCCCTGAGCTTACTTTGGCCTAGGCATCTTCATTGTCGTGGCTTGGAGCCTC
CCAAAGTGTGGTCCTGTGTGCCCTGTAGCCAGCCAGGGCATAGGAACCTTTAAGAGGGCCCAGC
CTTGTACCGACTGACCAAACCTCACTTCCTTCTCTGAGCCTGGAGCCTCAGCTTCACTGGATAC
AGCTCCTCCAGTACCGGTGGAACCCATACCGGTGGCACCCATCTCACCCCAAGCTGCTGGGTGC
AGCTGTACCTGAACTCCAATCCTGGCTGATGCAGAAAAACACTCAATATGCTTGACCAGGAACT
TCCCGTGTTATCACTTCCGTGGGCCCCGGTGACCTCACAGATCCTTCTGTACCCCACTTTCATC
TGGCAGTCCCGGCCTCAAGCTTCTGGGACCCGGTGTTCTCGGAAGAACGGACTGGGAGCCCAGC
ATGCCAATTTGGAGCCTCGAAGCTGGACACGGGCTCTTCCTCCCTCCTATACCCTGTATAAAGT
GACGTGTGAGCATGC

hide sequence

RefSeq Acc Id:

XM_039089599 ⟹ XP_038945527

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	41,541,868 - 41,557,779 (-)	NCBI
mRatBN7.2	12	35,881,269 - 35,897,186 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101805	(Get FASTA)	NCBI Sequence Viewer
	NP_001424493	(Get FASTA)	NCBI Sequence Viewer
	XP_006249457	(Get FASTA)	NCBI Sequence Viewer
	XP_017453888	(Get FASTA)	NCBI Sequence Viewer
	XP_038945527	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM13771	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001856
	ENSRNOP00000001856.6

RefSeq Acc Id:

NP_001101805 ⟸ NM_001108335

- UniProtKB:

D3ZHY9 (UniProtKB/TrEMBL), A6J1I2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKSGSLSIRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATIWRSLSPFWGEEYTVHLPLD
FHHLAFYVLDEDTVGHDDIIGKISLSKEAITADPRGIDSWINLSRVDPDEEVQGEVCLAVKLLE
DARGRCLRCHVRQARDLAPRDISGTSDPFARVFWGSRSLETSTIKKTRFPHWDEVLELREAPGT
TSPLRVELWDWDMVGKNDFLGMVEFTPQTLQQKPPNGWFRLLPFPRAEDSGGSLGALRLKVRLT
EDRVLPSQYYQPLMELLLESVQGPAEEDTTSPLALLEELASGDCRQDLATKLVKLFLGRGLAGP
FLDYLTRREVARTNDPNTLFRSNSLASKSMEQFMKLVGMRYLHEVLRPVISRVFEEKKYMELDP
SKMDLNRSRRISFKGTPTEEQVRETSLGLLTGYLGSVVDAIVSSAGRCPLALRLAFKQLQQCVE
KRFPGMEHQDVKYLATSGFLFLRFFAPAILTPKLFDLRDHHADPQTSRSLLLLAKAVQSIGNLG
QQLGQGKEQWLAPLHPFLLQSISRVRDFLDQLVDVDGDEEAGGSTCALVQPSTIVREGFLLKRK
EEPASLATRFAFKKRYFRLSGRDLSYSKTPEWQVHSSIPLSCIRAVERVDEGAFQLPHVMQVVT
QDGTGASHTTYLQCKNVNDLNQWLSALRKASAPNPGKLAACHPGAFRSGRWTCCLQAERSAVGC
SRTHSAVTLGDWSDPLDPDAEAQMVYRQLLLGRDQLRLKLLEDSSLDTAPDVDPGKDSSAVDGP
CAEVLAQQREATTRLLQVLEDLEQAHEEFQKRG

hide sequence

RefSeq Acc Id:

XP_006249457 ⟸ XM_006249395

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAKSGSLSIRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATIWRSLSPFWGEEYTVHLPLD
FHHLAFYVLDEDTVGHDDIIGKISLSKEAITADPRGIDSWINLSRVDPDEEVQGEVCLAVKLLE
DARGRCLRCHVRQARDLAPRDISGTSDPFARVFWGSRSLETSTIKKTRFPHWDEVLELREAPGT
TSPLRVELWDWDMVGKNDFLGMVEFTPQTLQQKPPNGWFRLLPFPRAEDSGGSLGALRLKVRLT
EDRVLPSQYYQPLMELLLESVQGPAEEDTTSPLALLEELASGDCRQDLATKLVKLFLGRGLAGP
FLDYLTRREVARTNDPNTLFRSNSLASKSMEQFMKLVGMRYLHEVLRPVISRVFEEKKYMELDP
SKMDLNRSRRISFKGTPTEEQVRETSLGLLTGYLGSVVDAIVSSAGRCPLALRLAFKQLQQCVE
KRFPGMEHQDVKYLATSGFLFLRFFAPAILTPKLFDLRDHHADPQTSRSLLLLAKAVQSIGNLG
QQLGQGKEQWLAPLHPFLLQSISRVRDFLDQLVDVDGDEEAGGSTCALVQPSTIVREGFLLKRK
EEPASLATRFAFKKRYFRLSGRDLSYSKTPEWQVHSSIPLSCIRAVERVDEGAFQLPHVMQVVT
QDGTGASHTTYLQCKNVNDLNQWLSALRKASAPNPGKLAACHPGAFRSGRWTCCLQAERSAVGC
SRTHSAVTLGDWSDPLDPDAEAQMVYRQLLLGRDQLRLKLLEDSSLDTAPDVDPGKDSSAVDGP
CAEVLAQQREATTRLLQVLEDLEQAHEEFQKRG

hide sequence

RefSeq Acc Id:

XP_017453888 ⟸ XM_017598399

- Peptide Label:

isoform X3

- Sequence:

show sequence

MRCWNYERLREPHPRCEWNSGIGTWWAKMTSWVEFTPQTLQQKPPNGWFRLLPFPRAEDSGGSL
GALRLKVRLTEDRVLPSQYYQPLMELLLESVQGPAEEDTTSPLALLEELASGDCRQDLATKLVK
LFLGRGLAGPFLDYLTRREVARTNDPNTLFRSNSLASKSMEQFMKLVGMRYLHEVLRPVISRVF
EEKKYMELDPSKMDLNRSRRISFKGTPTEEQVRETSLGLLTGYLGSVVDAIVSSAGRCPLALRL
AFKQLQQCVEKRFPGMEHQDVKYLATSGFLFLRFFAPAILTPKLFDLRDHHADPQTSRSLLLLA
KAVQSIGNLGQQLGQGKEQWLAPLHPFLLQSISRVRDFLDQLVDVDGDEEAGGSTCALVQPSTI
VREGFLLKRKEEPASLATRFAFKKRYFRLSGRDLSYSKTPEWQVHSSIPLSCIRAVERVDEGAF
QLPHVMQVVTQDGTGASHTTYLQCKNVNDLNQWLSALRKASAPNPGKLAACHPGAFRSGRWTCC
LQAERSAVGCSRTHSAVTLGDWSDPLDPDAEAQMVYRQLLLGRDQLRLKLLEDSSLDTAPDVDP
GKDSSAVDGPCAEVLAQQREATTRLLQVLEDLEQAHEEFQKRG

hide sequence

Ensembl Acc Id:

ENSRNOP00000001856 ⟸ ENSRNOT00000001856

RefSeq Acc Id:	XP_038945527 ⟸ XM_039089599
- Peptide Label:	isoform X2

Protein Domains

C2 PH Ras-GAP

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZHY9-F1-model_v2	AlphaFold	D3ZHY9	1-801	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311820	AgrOrtholog
BioCyc Gene	G2FUF-19187	BioCyc
Ensembl Genes	ENSRNOG00000001374	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001856	ENTREZGENE
	ENSRNOT00000001856.8	UniProtKB/TrEMBL
Gene3D-CATH	2.30.29.30	UniProtKB/TrEMBL
	2.60.40.150	UniProtKB/TrEMBL
	GTPase Activation - p120gap, domain 1	UniProtKB/TrEMBL
InterPro	C2_Ca-dep	UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/TrEMBL
	PH_like_dom	UniProtKB/TrEMBL
	Pleckstrin_homology	UniProtKB/TrEMBL
	Ras_GTPase	UniProtKB/TrEMBL
	RASAL_RasGAP	UniProtKB/TrEMBL
	RasGAP	UniProtKB/TrEMBL
	RasGAP_CS	UniProtKB/TrEMBL
	Rho_GTPase_activation_prot	UniProtKB/TrEMBL
	Znf_Btk_motif	UniProtKB/TrEMBL
KEGG Report	rno:360814	UniProtKB/TrEMBL
NCBI Gene	360814	ENTREZGENE
PANTHER	PTHR10194	UniProtKB/TrEMBL
	PTHR10194:SF3	UniProtKB/TrEMBL
Pfam	BTK	UniProtKB/TrEMBL
	PF00168	UniProtKB/TrEMBL
	PF00169	UniProtKB/TrEMBL
	RasGAP	UniProtKB/TrEMBL
PhenoGen	Rasal1	PhenoGen
PROSITE	PH_DOMAIN	UniProtKB/TrEMBL
	PS50004	UniProtKB/TrEMBL
	RAS_GTPASE_ACTIV_1	UniProtKB/TrEMBL
	RAS_GTPASE_ACTIV_2	UniProtKB/TrEMBL
	ZF_BTK	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000001374	RatGTEx
SMART	BTK	UniProtKB/TrEMBL
	RasGAP	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
	SM00239	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
	Rho_GAP	UniProtKB/TrEMBL
	SSF49562	UniProtKB/TrEMBL
UniProt	A6J1I2	ENTREZGENE, UniProtKB/TrEMBL
	D3ZHY9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-03-27	Rasal1	RAS protein activator like 1	Rasal1	RAS protein activator like 1 (GAP1 like)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Rasal1	RAS protein activator like 1 (GAP1 like)	Rasal1_predicted	RAS protein activator like 1 (GAP1 like) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Rasal1_predicted	RAS protein activator like 1 (GAP1 like) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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