Spred3 (sprouty-related, EVH1 domain containing 3) - Rat Genome Database

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Gene: Spred3 (sprouty-related, EVH1 domain containing 3) Rattus norvegicus
Analyze
Symbol: Spred3
Name: sprouty-related, EVH1 domain containing 3
RGD ID: 1311713
Description: Predicted to enable protein kinase binding activity. Predicted to be involved in negative regulation of cell differentiation and negative regulation of signal transduction. Predicted to act upstream of or within negative regulation of MAPK cascade. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human SPRED3 (sprouty related EVH1 domain containing 3); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC308478; RGD1311713; similar to SPRED-3; sprouty-related, EVH1 domain-containing protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8193,586,259 - 93,597,692 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl193,586,259 - 93,598,254 (-)EnsemblGRCr8
mRatBN7.2184,458,779 - 84,470,425 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl184,459,314 - 84,470,249 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx189,872,704 - 89,881,508 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0198,332,276 - 98,341,081 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0191,628,551 - 91,637,355 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0188,101,213 - 88,112,719 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,103,719 - 88,112,683 (-)Ensemblrn6Rnor6.0
Rnor_5.0189,276,366 - 89,288,460 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4184,295,411 - 84,303,809 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera178,849,116 - 78,857,919 (-)NCBICelera
RGSC_v3.1184,373,627 - 84,381,978 (-)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12646235  


Genomics

Comparative Map Data
Spred3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8193,586,259 - 93,597,692 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl193,586,259 - 93,598,254 (-)EnsemblGRCr8
mRatBN7.2184,458,779 - 84,470,425 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl184,459,314 - 84,470,249 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx189,872,704 - 89,881,508 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0198,332,276 - 98,341,081 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0191,628,551 - 91,637,355 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0188,101,213 - 88,112,719 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,103,719 - 88,112,683 (-)Ensemblrn6Rnor6.0
Rnor_5.0189,276,366 - 89,288,460 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4184,295,411 - 84,303,809 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera178,849,116 - 78,857,919 (-)NCBICelera
RGSC_v3.1184,373,627 - 84,381,978 (-)NCBI
Cytogenetic Map1q21NCBI
SPRED3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381938,388,697 - 38,399,587 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1938,388,421 - 38,399,588 (+)Ensemblhg38GRCh38
GRCh371938,879,337 - 38,890,227 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361943,572,779 - 43,578,711 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1935,683,176 - 35,689,108 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1935,328,434 - 35,338,118 (+)NCBIHuRef
CHM1_11938,881,181 - 38,890,884 (+)NCBICHM1_1
T2T-CHM13v2.01941,190,872 - 41,201,764 (+)NCBIT2T-CHM13v2.0
Spred3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39728,857,208 - 28,869,286 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl728,858,254 - 28,869,836 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38729,157,783 - 29,170,070 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl729,158,829 - 29,170,411 (-)Ensemblmm10GRCm38
MGSCv37729,943,848 - 29,953,666 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36728,867,589 - 28,877,407 (-)NCBIMGSCv36mm8
Celera723,728,916 - 23,738,734 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map716.94NCBI
Spred3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554681,028,470 - 1,039,495 (-)Ensembl
ChiLan1.0NW_0049554681,030,964 - 1,039,495 (-)NCBIChiLan1.0ChiLan1.0
SPRED3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22044,679,588 - 44,694,147 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11946,550,178 - 46,564,482 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01935,482,436 - 35,490,745 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11944,054,260 - 44,063,677 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1944,054,053 - 44,061,962 (+)EnsemblpanPan2panpan1.1
SPRED3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11114,604,265 - 114,614,764 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1114,607,058 - 114,685,985 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1114,007,038 - 114,017,781 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01115,205,031 - 115,214,900 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1115,205,635 - 115,214,348 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11114,778,010 - 114,788,747 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01114,395,603 - 114,406,341 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01115,434,230 - 115,444,965 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Spred3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934912,984,178 - 12,994,866 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368011,150,782 - 1,160,178 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049368011,150,897 - 1,160,016 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPRED3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl647,298,634 - 47,310,181 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1647,302,211 - 47,312,034 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2642,802,062 - 42,812,481 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPRED3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1633,031,118 - 33,038,988 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl633,032,718 - 33,038,570 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607310,977,257 - 10,988,507 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spred3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479411,850,625 - 11,858,755 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479411,850,570 - 11,861,125 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Spred3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12166,824,567 - 166,835,920 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Spred3
100 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:28
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000065850
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 162 91 90 59 92 59 6 355 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000077195   ⟹   ENSRNOP00000072996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl188,103,719 - 88,111,293 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000083817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl184,467,580 - 84,469,776 (-)Ensembl
Rnor_6.0 Ensembl188,110,014 - 88,112,210 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090615   ⟹   ENSRNOP00000072614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl193,588,930 - 93,597,729 (-)Ensembl
mRatBN7.2 Ensembl184,461,450 - 84,470,249 (-)Ensembl
Rnor_6.0 Ensembl188,104,013 - 88,112,683 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113063   ⟹   ENSRNOP00000086038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl193,586,259 - 93,595,668 (-)Ensembl
mRatBN7.2 Ensembl184,459,314 - 84,468,322 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000138145   ⟹   ENSRNOP00000098719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl193,586,259 - 93,595,254 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000141561   ⟹   ENSRNOP00000098933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl193,586,259 - 93,597,110 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000144520   ⟹   ENSRNOP00000105772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl193,586,259 - 93,597,575 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000168528   ⟹   ENSRNOP00000111318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl193,588,930 - 93,598,254 (-)Ensembl
RefSeq Acc Id: NM_001415863   ⟹   NP_001402792
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8193,586,259 - 93,597,242 (-)NCBI
mRatBN7.2184,458,779 - 84,469,762 (-)NCBI
RefSeq Acc Id: NR_183230
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8193,586,259 - 93,597,242 (-)NCBI
mRatBN7.2184,458,779 - 84,469,762 (-)NCBI
RefSeq Acc Id: XM_008759145   ⟹   XP_008757367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8193,586,260 - 93,597,692 (-)NCBI
mRatBN7.2184,458,779 - 84,470,425 (-)NCBI
Rnor_6.0188,101,213 - 88,112,719 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008759146   ⟹   XP_008757368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8193,586,260 - 93,595,900 (-)NCBI
mRatBN7.2184,458,779 - 84,468,441 (-)NCBI
Rnor_6.0188,101,213 - 88,110,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589125   ⟹   XP_017444614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8193,586,260 - 93,597,689 (-)NCBI
mRatBN7.2184,458,779 - 84,470,425 (-)NCBI
Rnor_6.0188,101,213 - 88,112,719 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039111582   ⟹   XP_038967510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8193,586,260 - 93,597,247 (-)NCBI
mRatBN7.2184,458,779 - 84,469,762 (-)NCBI
RefSeq Acc Id: XM_039111583   ⟹   XP_038967511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8193,586,260 - 93,595,898 (-)NCBI
mRatBN7.2184,458,779 - 84,468,440 (-)NCBI
RefSeq Acc Id: XP_008757367   ⟸   XM_008759145
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008757368   ⟸   XM_008759146
- Peptide Label: isoform X3
- UniProtKB: A0A096MJ78 (UniProtKB/TrEMBL),   A6J9N6 (UniProtKB/TrEMBL),   A0A0G2K3F4 (UniProtKB/TrEMBL),   B2GV40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444614   ⟸   XM_017589125
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000072996   ⟸   ENSRNOT00000077195
Ensembl Acc Id: ENSRNOP00000072614   ⟸   ENSRNOT00000090615
RefSeq Acc Id: XP_038967510   ⟸   XM_039111582
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K3F4 (UniProtKB/TrEMBL),   B2GV40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967511   ⟸   XM_039111583
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K3F4 (UniProtKB/TrEMBL),   B2GV40 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000086038   ⟸   ENSRNOT00000113063
RefSeq Acc Id: NP_001402792   ⟸   NM_001415863
- UniProtKB: A0A096MJ78 (UniProtKB/TrEMBL),   A6J9N6 (UniProtKB/TrEMBL),   A0A0G2K3F4 (UniProtKB/TrEMBL),   B2GV40 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105772   ⟸   ENSRNOT00000144520
Ensembl Acc Id: ENSRNOP00000098719   ⟸   ENSRNOT00000138145
Ensembl Acc Id: ENSRNOP00000098933   ⟸   ENSRNOT00000141561
Ensembl Acc Id: ENSRNOP00000111318   ⟸   ENSRNOT00000168528
Protein Domains
KBD   WH1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MJ78-F1-model_v2 AlphaFold A0A096MJ78 1-410 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689904
Promoter ID:EPDNEW_R424
Type:single initiation site
Name:Spred3_1
Description:sprouty-related, EVH1 domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0188,112,161 - 88,112,221EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311713 AgrOrtholog
BioCyc Gene G2FUF-60192 BioCyc
Ensembl Genes ENSRNOG00000051915 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000090615 ENTREZGENE
  ENSRNOT00000090615.3 UniProtKB/TrEMBL
  ENSRNOT00000113063 ENTREZGENE
  ENSRNOT00000113063.2 UniProtKB/TrEMBL
  ENSRNOT00000138145 ENTREZGENE
  ENSRNOT00000138145.1 UniProtKB/TrEMBL
  ENSRNOT00000141561.1 UniProtKB/TrEMBL
  ENSRNOT00000144520 ENTREZGENE
  ENSRNOT00000144520.1 UniProtKB/TrEMBL
  ENSRNOT00000168528.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131550 IMAGE-MGC_LOAD
InterPro EVH1 UniProtKB/TrEMBL
  KBD UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  SPRE_EVH1 UniProtKB/TrEMBL
  Sprouty UniProtKB/TrEMBL
MGC_CLONE MGC:188090 IMAGE-MGC_LOAD
NCBI Gene 308478 ENTREZGENE
PANTHER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
  SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam Sprouty UniProtKB/TrEMBL
  WH1 UniProtKB/TrEMBL
PhenoGen Spred3 PhenoGen
PROSITE KBD UniProtKB/TrEMBL
  SPR UniProtKB/TrEMBL
  WH1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051915 RatGTEx
SMART WH1 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A096MJ78 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K3F4 ENTREZGENE
  A0ABK0LCJ4_RAT UniProtKB/TrEMBL
  A0ABK0LDY7_RAT UniProtKB/TrEMBL
  A0ABK0LK41_RAT UniProtKB/TrEMBL
  A0ABK0LXY1_RAT UniProtKB/TrEMBL
  A6J9N6 ENTREZGENE, UniProtKB/TrEMBL
  B2GV40 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A0G2K3F4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-27 Spred3  sprouty-related, EVH1 domain containing 3  RGD1311713_predicted  similar to SPRED-3 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1311713_predicted  similar to SPRED-3 (predicted)  LOC308478_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC308478_predicted  similar to SPRED-3 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL