Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Terf1 | Rat | (+)-dexrazoxane | multiple interactions | ISO | Terf1 (Mus musculus) | 6480464 | Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of TERF1 mRNA] | CTD | PMID:28973540 | Terf1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Terf1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TERF1 mRNA | CTD | PMID:22206623 | Terf1 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 more ... | CTD | PMID:26330309 | Terf1 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of TERF1 mRNA | CTD | PMID:26330309 | Terf1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TERF1 mRNA | CTD | PMID:21215274|PMID:33387578 | Terf1 | Rat | 2-butoxyethanol | increases expression | ISO | Terf1 (Mus musculus) | 6480464 | n-butoxyethanol results in increased expression of TERF1 mRNA | CTD | PMID:19812364 | Terf1 | Rat | 2-methylcholine | affects expression | ISO | TERF1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of TERF1 mRNA | CTD | PMID:21179406 | Terf1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 more ... | CTD | PMID:26330309 | Terf1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TERF1 mRNA | CTD | PMID:26330309 | Terf1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Terf1 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Terf1 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of TERF1 mRNA | CTD | PMID:18648102 | Terf1 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Terf1 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of TERF1 mRNA | CTD | PMID:39298647 | Terf1 | Rat | 4-hydroxynon-2-enal | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of TERF1 mRNA | CTD | PMID:12419474 | Terf1 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TERF1 mRNA | CTD | PMID:24780913 | Terf1 | Rat | aflatoxin M1 | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of TERF1 mRNA | CTD | PMID:30928695 | Terf1 | Rat | all-trans-retinoic acid | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 more ... | CTD | PMID:26330309 | Terf1 | Rat | amiodarone | increases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of TERF1 mRNA | CTD | PMID:19774075 | Terf1 | Rat | aristolochic acid A | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TERF1 mRNA | CTD | PMID:33212167 | Terf1 | Rat | arsenous acid | increases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TERF1 mRNA; Arsenic Trioxide results in increased expression more ... | CTD | PMID:15904916 | Terf1 | Rat | atrazine | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of TERF1 mRNA | CTD | PMID:22378314 | Terf1 | Rat | benzo[a]pyrene | affects methylation | ISO | TERF1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TERF1 promoter | CTD | PMID:27901495 | Terf1 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TERF1 mRNA | CTD | PMID:20018196 | Terf1 | Rat | beta-lapachone | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of TERF1 mRNA | CTD | PMID:38218311 | Terf1 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Terf1 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TRF1 mRNA; Diethylhexyl Phthalate results in decreased expression more ... | CTD | PMID:36174712 | Terf1 | Rat | bisphenol A | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Terf1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TERF1 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016 | Terf1 | Rat | bisphenol F | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Terf1 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of TERF1 promoter | CTD | PMID:22457795 | Terf1 | Rat | chlorpyrifos | decreases expression | ISO | Terf1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of TERF1 mRNA | CTD | PMID:37019170 | Terf1 | Rat | ciguatoxin CTX1B | affects expression | ISO | Terf1 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of TERF1 mRNA | CTD | PMID:18353800 | Terf1 | Rat | cyclosporin A | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TERF1 mRNA | CTD | PMID:25562108 | Terf1 | Rat | cypermethrin | increases expression | ISO | Terf1 (Mus musculus) | 6480464 | cypermethrin results in increased expression of TERF1 mRNA | CTD | PMID:21142847 | Terf1 | Rat | dexamethasone | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Terf1 | Rat | diarsenic trioxide | increases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TERF1 mRNA; Arsenic Trioxide results in increased expression more ... | CTD | PMID:15904916 | Terf1 | Rat | dicrotophos | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of TERF1 mRNA | CTD | PMID:28302478 | Terf1 | Rat | dimethyl sulfoxide | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 more ... | CTD | PMID:26330309 | Terf1 | Rat | dorsomorphin | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Terf1 | Rat | doxorubicin | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TERF1 mRNA | CTD | PMID:29803840 | Terf1 | Rat | elemental selenium | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Selenium results in decreased expression of TERF1 mRNA | CTD | PMID:19244175 | Terf1 | Rat | elemental selenium | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of TERF1 mRNA | CTD | PMID:19244175 | Terf1 | Rat | ethanol | affects expression | ISO | Terf1 (Mus musculus) | 6480464 | Ethanol affects the expression of TERF1 mRNA | CTD | PMID:26730594 | Terf1 | Rat | ethanol | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | NFATC4 protein affects the reaction [Ethanol results in increased expression of TERF1 mRNA]; NFATC4 protein more ... | CTD | PMID:34192554|PMID:34405320 | Terf1 | Rat | ethanol | increases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Ethanol results in increased expression of TERF1 mRNA; Ethanol results in increased expression of TERF1 more ... | CTD | PMID:34192554|PMID:34405320 | Terf1 | Rat | folic acid | multiple interactions | ISO | Terf1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TERF1 mRNA | CTD | PMID:22206623 | Terf1 | Rat | FR900359 | decreases phosphorylation | ISO | TERF1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of TERF1 protein | CTD | PMID:37730182 | Terf1 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TERF1 mRNA | CTD | PMID:20562052 | Terf1 | Rat | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of TERF1 mRNA | CTD | PMID:22507866 | Terf1 | Rat | geraniol | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | geraniol results in decreased expression of TERF1 mRNA | CTD | PMID:27683099 | Terf1 | Rat | idarubicin | multiple interactions | ISO | Terf1 (Mus musculus) | 6480464 | Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of TERF1 mRNA] | CTD | PMID:28973540 | Terf1 | Rat | idarubicin | decreases expression | ISO | Terf1 (Mus musculus) | 6480464 | Idarubicin results in decreased expression of TERF1 mRNA | CTD | PMID:28973540 | Terf1 | Rat | indometacin | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Terf1 | Rat | lead(0) | affects splicing | ISO | TERF1 (Homo sapiens) | 6480464 | Lead affects the splicing of TERF1 mRNA | CTD | PMID:28903495 | Terf1 | Rat | methamphetamine | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of TERF1 mRNA | CTD | PMID:19564919 | Terf1 | Rat | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of TERF1 mRNA | CTD | PMID:19564919 | Terf1 | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Terf1 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of TRF1 protein | CTD | PMID:36174712 | Terf1 | Rat | N(4)-hydroxycytidine | decreases expression | ISO | Terf1 (Mus musculus) | 6480464 | N(4)-hydroxycytidine results in decreased expression of TERF1 mRNA | CTD | PMID:37748715 | Terf1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of TERF1 mRNA | CTD | PMID:25729387 | Terf1 | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of TERF1 mRNA | CTD | PMID:25729387 | Terf1 | Rat | phenylmercury acetate | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of TERF1 mRNA | CTD | PMID:26272509 | Terf1 | Rat | phenylmercury acetate | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Terf1 | Rat | phenytoin | increases expression | EXP | | 6480464 | Phenytoin results in increased expression of TERF1 mRNA | CTD | PMID:20345932 | Terf1 | Rat | phorbol 13-acetate 12-myristate | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TERF1 mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with more ... | CTD | PMID:26330309 | Terf1 | Rat | phosphoramide mustard | increases expression | EXP | | 6480464 | phosphoramide mustard results in increased expression of TERF1 mRNA | CTD | PMID:26708502 | Terf1 | Rat | pirinixic acid | decreases expression | ISO | Terf1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TERF1 mRNA | CTD | PMID:18445702 | Terf1 | Rat | pterostilbene | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | pterostilbene inhibits the reaction [Ethanol results in increased expression of TERF1 protein] | CTD | PMID:34405320 | Terf1 | Rat | resveratrol | affects localization | ISO | TERF1 (Homo sapiens) | 6480464 | resveratrol affects the localization of TERF1 protein | CTD | PMID:19559722 | Terf1 | Rat | SB 431542 | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Terf1 | Rat | SCH 23390 | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of TERF1 mRNA | CTD | PMID:19564919 | Terf1 | Rat | selenium atom | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Selenium results in decreased expression of TERF1 mRNA | CTD | PMID:19244175 | Terf1 | Rat | selenium atom | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of TERF1 mRNA | CTD | PMID:19244175 | Terf1 | Rat | sodium arsenite | affects expression | ISO | TERF1 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of TERF1 mRNA | CTD | PMID:29319823 | Terf1 | Rat | sodium arsenite | decreases expression | ISO | Terf1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TERF1 mRNA | CTD | PMID:36209798 | Terf1 | Rat | sodium arsenite | decreases methylation | ISO | Terf1 (Mus musculus) | 6480464 | sodium arsenite results in decreased methylation of TERF1 gene | CTD | PMID:32068019 | Terf1 | Rat | sunitinib | increases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TERF1 mRNA | CTD | PMID:31533062 | Terf1 | Rat | tebuconazole | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | tebuconazole results in decreased expression of TERF1 mRNA | CTD | PMID:30458266 | Terf1 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of TERF1 mRNA | CTD | PMID:12419474 | Terf1 | Rat | tetrachloromethane | increases expression | ISO | Terf1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of TERF1 mRNA | CTD | PMID:31919559 | Terf1 | Rat | titanium dioxide | decreases methylation | ISO | Terf1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TERF1 gene | CTD | PMID:35295148 | Terf1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of TERF1 mRNA | CTD | PMID:25729387 | Terf1 | Rat | triphenyl phosphate | affects expression | ISO | TERF1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TERF1 mRNA | CTD | PMID:37042841 | Terf1 | Rat | triptonide | decreases expression | ISO | Terf1 (Mus musculus) | 6480464 | triptonide results in decreased expression of TERF1 mRNA | CTD | PMID:33045310 | Terf1 | Rat | tungsten | increases expression | ISO | Terf1 (Mus musculus) | 6480464 | Tungsten results in increased expression of TERF1 mRNA | CTD | PMID:30912803 | Terf1 | Rat | valproic acid | affects expression | ISO | TERF1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TERF1 mRNA | CTD | PMID:25979313 | Terf1 | Rat | vitamin E | multiple interactions | ISO | TERF1 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of TERF1 mRNA | CTD | PMID:19244175 | Terf1 | Rat | vitamin E | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of TERF1 mRNA | CTD | PMID:19244175 | Terf1 | Rat | vorinostat | decreases expression | ISO | TERF1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of TERF1 mRNA | CTD | PMID:27188386 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















