Ralgps2 (Ral GEF with PH domain and SH3 binding motif 2) - Rat Genome Database

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Gene: Ralgps2 (Ral GEF with PH domain and SH3 binding motif 2) Rattus norvegicus
Analyze
Symbol: Ralgps2
Name: Ral GEF with PH domain and SH3 binding motif 2
RGD ID: 1311537
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to human RALGPS2 (Ral GEF with PH domain and SH3 binding motif 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC304887; Ral-A exchange factor RalGPS2; ras-specific guanine nucleotide-releasing factor RalGPS2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81371,474,835 - 71,654,791 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1371,474,835 - 71,606,739 (-)EnsemblGRCr8
mRatBN7.21368,924,674 - 69,104,637 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1368,928,474 - 69,056,549 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1371,513,084 - 71,644,768 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01372,829,270 - 72,960,993 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01370,090,752 - 70,222,479 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01374,446,001 - 74,520,640 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1374,422,944 - 74,564,184 (-)Ensemblrn6Rnor6.0
Rnor_5.01379,366,278 - 79,441,831 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41372,028,711 - 72,106,310 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1368,815,784 - 68,888,801 (-)NCBICelera
RGSC_v3.11372,018,941 - 72,120,498 (-)NCBI
Cytogenetic Map13q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycidol  (EXP)
inulin  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
nickel atom  (ISO)
nitrates  (ISO)
oxaliplatin  (EXP)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
rac-lactic acid  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
testosterone  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10747847   PMID:12477932   PMID:20025911  


Genomics

Comparative Map Data
Ralgps2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81371,474,835 - 71,654,791 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1371,474,835 - 71,606,739 (-)EnsemblGRCr8
mRatBN7.21368,924,674 - 69,104,637 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1368,928,474 - 69,056,549 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1371,513,084 - 71,644,768 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01372,829,270 - 72,960,993 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01370,090,752 - 70,222,479 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01374,446,001 - 74,520,640 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1374,422,944 - 74,564,184 (-)Ensemblrn6Rnor6.0
Rnor_5.01379,366,278 - 79,441,831 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41372,028,711 - 72,106,310 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1368,815,784 - 68,888,801 (-)NCBICelera
RGSC_v3.11372,018,941 - 72,120,498 (-)NCBI
Cytogenetic Map13q22NCBI
RALGPS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381178,725,244 - 178,921,840 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1178,725,165 - 178,921,842 (+)Ensemblhg38GRCh38
GRCh371178,694,379 - 178,890,975 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,960,923 - 177,152,468 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341175,425,956 - 175,617,499NCBI
Celera1151,803,392 - 151,998,084 (+)NCBICelera
Cytogenetic Map1q25.2NCBI
HuRef1149,922,359 - 150,116,845 (+)NCBIHuRef
CHM1_11180,118,072 - 180,312,957 (+)NCBICHM1_1
T2T-CHM13v2.01178,079,963 - 178,276,579 (+)NCBIT2T-CHM13v2.0
Ralgps2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391156,631,736 - 156,767,422 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1156,631,736 - 156,767,196 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381156,804,166 - 156,939,850 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1156,804,166 - 156,939,626 (-)Ensemblmm10GRCm38
MGSCv371158,734,297 - 158,869,757 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361158,644,799 - 158,776,257 (-)NCBIMGSCv36mm8
Celera1159,199,228 - 159,302,839 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map167.71NCBI
Ralgps2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540618,161,585 - 18,262,436 (+)Ensembl
ChiLan1.0NW_00495540618,161,587 - 18,267,737 (+)NCBIChiLan1.0ChiLan1.0
RALGPS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2170,831,325 - 71,018,430 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1170,495,627 - 70,687,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01154,224,362 - 154,411,202 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11157,914,966 - 158,102,772 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1157,916,856 - 158,097,550 (+)EnsemblpanPan2panpan1.1
RALGPS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1720,874,227 - 21,031,817 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl720,879,492 - 21,005,154 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha720,400,933 - 20,559,320 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0720,613,124 - 20,771,562 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl720,605,988 - 20,771,639 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1720,520,068 - 20,678,454 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0720,628,185 - 20,786,321 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0720,763,086 - 20,921,523 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ralgps2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934492,155,131 - 92,283,569 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648110,007,336 - 10,130,414 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648110,002,132 - 10,130,577 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGPS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9120,420,942 - 120,724,218 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19120,562,294 - 120,725,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29132,301,508 - 132,345,891 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGPS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12550,419,505 - 50,601,821 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2550,424,998 - 50,601,673 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605551,948,165 - 52,129,943 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ralgps2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247713,430,226 - 3,573,003 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247713,425,210 - 3,573,022 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ralgps2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11036,152,498 - 36,279,236 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ralgps2
1366 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:238
Count of miRNA genes:164
Interacting mature miRNAs:191
Transcripts:ENSRNOT00000036200
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)137161080489333251Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)137161080489333251Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)137161080489333251Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
D13Rat85  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81371,610,804 - 71,610,940 (+)Marker Load Pipeline
mRatBN7.21369,060,519 - 69,060,785 (+)MAPPERmRatBN7.2
mRatBN7.21369,060,649 - 69,060,785 (+)MAPPERmRatBN7.2
Rnor_6.01374,568,378 - 74,568,698NCBIRnor6.0
Rnor_6.01374,568,563 - 74,568,698NCBIRnor6.0
Rnor_5.01379,489,166 - 79,489,301UniSTSRnor5.0
Rnor_5.01379,488,981 - 79,489,301UniSTSRnor5.0
RGSC_v3.41372,141,292 - 72,141,428RGDRGSC3.4
RGSC_v3.41372,141,293 - 72,141,428UniSTSRGSC3.4
Celera1368,923,954 - 68,924,089UniSTS
RGSC_v3.11372,155,481 - 72,155,616RGD
RH 3.4 Map13394.3RGD
RH 3.4 Map13394.3UniSTS
SHRSP x BN Map1326.0799RGD
SHRSP x BN Map1326.0799UniSTS
FHH x ACI Map1330.3999RGD
Cytogenetic Map13q22UniSTS
D13Rat130  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81371,713,331 - 71,713,534 (+)Marker Load Pipeline
mRatBN7.21369,163,188 - 69,163,391 (+)MAPPERmRatBN7.2
Rnor_6.01374,672,405 - 74,672,607NCBIRnor6.0
Rnor_5.01379,589,799 - 79,590,001UniSTSRnor5.0
RGSC_v3.41372,283,276 - 72,283,478UniSTSRGSC3.4
RGSC_v3.41372,283,275 - 72,283,478RGDRGSC3.4
Celera1369,019,334 - 69,019,534UniSTS
RGSC_v3.11372,297,464 - 72,297,666RGD
RH 3.4 Map13374.5UniSTS
RH 3.4 Map13374.5RGD
SHRSP x BN Map1325.9999RGD
SHRSP x BN Map1325.9999UniSTS
Cytogenetic Map13q22UniSTS
RH129018  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21368,981,394 - 68,981,545 (+)MAPPERmRatBN7.2
Rnor_6.01374,474,696 - 74,474,846NCBIRnor6.0
Rnor_5.01379,395,854 - 79,396,004UniSTSRnor5.0
RGSC_v3.41372,057,879 - 72,058,029UniSTSRGSC3.4
Celera1368,844,471 - 68,844,621UniSTS
Cytogenetic Map13q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF296692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000036200   ⟹   ENSRNOP00000033737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1371,474,835 - 71,606,739 (-)Ensembl
mRatBN7.2 Ensembl1368,928,561 - 69,056,549 (-)Ensembl
Rnor_6.0 Ensembl1374,446,006 - 74,564,184 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077169   ⟹   ENSRNOP00000068725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1371,481,594 - 71,606,739 (-)Ensembl
mRatBN7.2 Ensembl1368,931,433 - 69,025,414 (-)Ensembl
Rnor_6.0 Ensembl1374,422,944 - 74,520,634 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103744   ⟹   ENSRNOP00000089573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1371,474,835 - 71,606,739 (-)Ensembl
mRatBN7.2 Ensembl1368,928,537 - 69,056,545 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116366   ⟹   ENSRNOP00000089846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1371,474,835 - 71,575,490 (-)Ensembl
mRatBN7.2 Ensembl1368,928,474 - 69,056,539 (-)Ensembl
RefSeq Acc Id: NM_001100680   ⟹   NP_001094150
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,502,873 - 71,606,694 (-)NCBI
mRatBN7.21368,952,712 - 69,056,539 (-)NCBI
Rnor_6.01374,446,001 - 74,520,640 (-)NCBI
Rnor_5.01379,366,278 - 79,441,831 (-)NCBI
RGSC_v3.41372,028,711 - 72,106,310 (-)RGD
Celera1368,815,784 - 68,888,801 (-)RGD
Sequence:
RefSeq Acc Id: NM_001401396   ⟹   NP_001388325
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,739 (-)NCBI
mRatBN7.21368,924,674 - 69,056,584 (-)NCBI
RefSeq Acc Id: XM_039090752   ⟹   XP_038946680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,406 (-)NCBI
mRatBN7.21368,929,265 - 69,056,155 (-)NCBI
RefSeq Acc Id: XM_039090753   ⟹   XP_038946681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,625,756 (-)NCBI
mRatBN7.21368,929,265 - 69,075,444 (-)NCBI
RefSeq Acc Id: XM_039090755   ⟹   XP_038946683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,592 (-)NCBI
mRatBN7.21368,929,265 - 69,056,443 (-)NCBI
RefSeq Acc Id: XM_039090756   ⟹   XP_038946684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,654,791 (-)NCBI
mRatBN7.21368,929,265 - 69,104,637 (-)NCBI
RefSeq Acc Id: XM_039090757   ⟹   XP_038946685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,330 (-)NCBI
mRatBN7.21368,929,265 - 69,056,155 (-)NCBI
RefSeq Acc Id: XM_039090758   ⟹   XP_038946686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,759 (-)NCBI
mRatBN7.21368,929,265 - 69,056,598 (-)NCBI
RefSeq Acc Id: XM_039090761   ⟹   XP_038946689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,568,386 (-)NCBI
mRatBN7.21368,929,265 - 69,018,229 (-)NCBI
RefSeq Acc Id: XM_063272333   ⟹   XP_063128403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,330 (-)NCBI
RefSeq Acc Id: XM_063272334   ⟹   XP_063128404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,340 (-)NCBI
RefSeq Acc Id: XM_063272335   ⟹   XP_063128405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,385 (-)NCBI
RefSeq Acc Id: XM_063272336   ⟹   XP_063128406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,352 (-)NCBI
RefSeq Acc Id: XM_063272338   ⟹   XP_063128408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,625,756 (-)NCBI
RefSeq Acc Id: XM_063272339   ⟹   XP_063128409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,453 (-)NCBI
RefSeq Acc Id: XM_063272340   ⟹   XP_063128410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,596 (-)NCBI
RefSeq Acc Id: XM_063272341   ⟹   XP_063128411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,606,340 (-)NCBI
RefSeq Acc Id: XM_063272342   ⟹   XP_063128412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81371,474,835 - 71,510,792 (-)NCBI
RefSeq Acc Id: NP_001094150   ⟸   NM_001100680
- Peptide Label: isoform 2
- UniProtKB: Q0VGK1 (UniProtKB/TrEMBL),   F1MAR5 (UniProtKB/TrEMBL),   A6ID21 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068725   ⟸   ENSRNOT00000077169
Ensembl Acc Id: ENSRNOP00000033737   ⟸   ENSRNOT00000036200
RefSeq Acc Id: XP_038946684   ⟸   XM_039090756
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GHG1 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946681   ⟸   XM_039090753
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GHG1 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946686   ⟸   XM_039090758
- Peptide Label: isoform X2
- UniProtKB: A0A8J8XSQ7 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946683   ⟸   XM_039090755
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GHG1 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946685   ⟸   XM_039090757
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GHG1 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946680   ⟸   XM_039090752
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GHG1 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946689   ⟸   XM_039090761
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A8Z1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000089573   ⟸   ENSRNOT00000103744
Ensembl Acc Id: ENSRNOP00000089846   ⟸   ENSRNOT00000116366
RefSeq Acc Id: NP_001388325   ⟸   NM_001401396
- Peptide Label: isoform 1
- UniProtKB: A0A8I6GHG1 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128408   ⟸   XM_063272338
- Peptide Label: isoform X2
- UniProtKB: A0A8J8XSQ7 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128410   ⟸   XM_063272340
- Peptide Label: isoform X2
- UniProtKB: A0A8J8XSQ7 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128409   ⟸   XM_063272339
- Peptide Label: isoform X2
- UniProtKB: A0A8J8XSQ7 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128405   ⟸   XM_063272335
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GHG1 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128406   ⟸   XM_063272336
- Peptide Label: isoform X2
- UniProtKB: A0A8J8XSQ7 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128411   ⟸   XM_063272341
- Peptide Label: isoform X2
- UniProtKB: A0A8J8XSQ7 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128404   ⟸   XM_063272334
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GHG1 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128403   ⟸   XM_063272333
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GHG1 (UniProtKB/TrEMBL),   A0A0G2JTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128412   ⟸   XM_063272342
- Peptide Label: isoform X4
Protein Domains
PH   Ras-GEF

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTI5-F1-model_v2 AlphaFold A0A0G2JTI5 1-611 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311537 AgrOrtholog
BioCyc Gene G2FUF-17801 BioCyc
Ensembl Genes ENSRNOG00000004736 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036200 ENTREZGENE
  ENSRNOT00000036200.6 UniProtKB/TrEMBL
  ENSRNOT00000077169.3 UniProtKB/TrEMBL
  ENSRNOT00000103744 ENTREZGENE
  ENSRNOT00000103744.2 UniProtKB/TrEMBL
  ENSRNOT00000116366 ENTREZGENE
  ENSRNOT00000116366.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.840.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7326132 IMAGE-MGC_LOAD
InterPro PH/PTB_dom UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  Ras-like_GEF UniProtKB/TrEMBL
  Ras_GEF_dom UniProtKB/TrEMBL
  RASGEF_cat_dom_sf UniProtKB/TrEMBL
  RasGRF_CDC25 UniProtKB/TrEMBL
KEGG Report rno:304887 UniProtKB/TrEMBL
MGC_CLONE MGC:125168 IMAGE-MGC_LOAD
NCBI Gene 304887 ENTREZGENE
PANTHER PTHR23113 UniProtKB/TrEMBL
  RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS2 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  RasGEF UniProtKB/TrEMBL
PhenoGen Ralgps2 PhenoGen
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  RASGEF_CAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004736 RatGTEx
SMART RasGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  Ras_GEF UniProtKB/TrEMBL
UniProt A0A0G2JTI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8Z1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GHG1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8XSQ7 ENTREZGENE, UniProtKB/TrEMBL
  A6ID20_RAT UniProtKB/TrEMBL
  A6ID21 ENTREZGENE, UniProtKB/TrEMBL
  F1MAR5 ENTREZGENE
  Q0VGK1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1MAR5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Ralgps2  Ral GEF with PH domain and SH3 binding motif 2  Ralgps2_predicted  Ral GEF with PH domain and SH3 binding motif 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ralgps2_predicted  Ral GEF with PH domain and SH3 binding motif 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED