Crlf1 (cytokine receptor-like factor 1) - Rat Genome Database

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Pathways
Gene: Crlf1 (cytokine receptor-like factor 1) Rattus norvegicus
Analyze
Symbol: Crlf1
Name: cytokine receptor-like factor 1
RGD ID: 1311371
Description: Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to contribute to ciliary neurotrophic factor receptor binding activity and cytokine activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; negative regulation of motor neuron apoptotic process; and ureteric bud development. Predicted to be located in extracellular region. Predicted to be part of CRLF-CLCF1 complex and receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 1. Orthologous to human CRLF1 (cytokine receptor like factor 1); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC290655
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,958,695 - 18,970,026 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1618,957,956 - 18,969,970 (-)EnsemblGRCr8
mRatBN7.21618,924,722 - 18,936,049 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,924,722 - 18,935,997 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1618,966,510 - 18,977,787 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,099,327 - 20,110,590 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,019,472 - 19,030,749 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,675,042 - 20,686,365 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,675,042 - 20,686,317 (-)Ensemblrn6Rnor6.0
Rnor_5.01620,530,521 - 20,541,831 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,431,472 - 19,442,747 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1619,116,098 - 19,127,373 (-)NCBICelera
RGSC_v3.11619,431,472 - 19,442,745 (-)NCBI
Cytogenetic Map16p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dinitrobenzenesulfonic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP)
amitrole  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
Cuprizon  (EXP)
cypermethrin  (EXP)
D-glucose  (ISO)
DDE  (ISO)
diazinon  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
fentanyl  (EXP)
folic acid  (ISO)
fucoxanthin  (ISO)
furan  (EXP)
glucose  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
maneb  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (EXP)
methylmercury chloride  (EXP)
miconazole  (ISO)
niclosamide  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP,ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorooctanoic acid  (ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
tributylstannane  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Cold-induced sweating syndrome is caused by mutations in the CRLF1 gene. Knappskog PM, etal., Am J Hum Genet. 2003 Feb;72(2):375-83. Epub 2002 Dec 31.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10966616   PMID:14523086   PMID:15034937   PMID:16545622   PMID:24006456  


Genomics

Comparative Map Data
Crlf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,958,695 - 18,970,026 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1618,957,956 - 18,969,970 (-)EnsemblGRCr8
mRatBN7.21618,924,722 - 18,936,049 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,924,722 - 18,935,997 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1618,966,510 - 18,977,787 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,099,327 - 20,110,590 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,019,472 - 19,030,749 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,675,042 - 20,686,365 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,675,042 - 20,686,317 (-)Ensemblrn6Rnor6.0
Rnor_5.01620,530,521 - 20,541,831 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,431,472 - 19,442,747 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1619,116,098 - 19,127,373 (-)NCBICelera
RGSC_v3.11619,431,472 - 19,442,745 (-)NCBI
Cytogenetic Map16p14NCBI
CRLF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,593,237 - 18,606,799 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,572,220 - 18,607,741 (-)Ensemblhg38GRCh38
GRCh371918,704,047 - 18,717,609 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,565,047 - 18,578,660 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341918,565,046 - 18,578,660NCBI
Celera1918,606,237 - 18,619,858 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,266,624 - 18,309,213 (-)NCBIHuRef
CHM1_11918,704,266 - 18,717,662 (-)NCBICHM1_1
T2T-CHM13v2.01918,728,303 - 18,741,874 (-)NCBIT2T-CHM13v2.0
Crlf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,945,798 - 70,956,728 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,945,808 - 70,956,731 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38870,493,097 - 70,504,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,493,158 - 70,504,081 (+)Ensemblmm10GRCm38
MGSCv37873,017,055 - 73,027,980 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36873,422,145 - 73,433,070 (+)NCBIMGSCv36mm8
Celera873,049,567 - 73,060,492 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Crlf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,998,260 - 3,003,283 (+)Ensembl
ChiLan1.0NW_0049555242,998,258 - 3,003,553 (+)NCBIChiLan1.0ChiLan1.0
CRLF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,452,262 - 23,465,525 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,460,674 - 22,473,911 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,070,465 - 18,083,701 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,040,355 - 19,048,927 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,040,682 - 19,046,584 (-)EnsemblpanPan2panpan1.1
CRLF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,466,812 - 44,476,055 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,466,810 - 44,472,637 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2044,376,895 - 44,389,992 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02044,948,405 - 44,961,499 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,948,246 - 44,958,835 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,185,771 - 44,198,860 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,595,729 - 44,608,819 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,871,168 - 44,884,262 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Crlf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,147,220 - 203,153,304 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,693,881 - 2,702,131 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,693,881 - 2,702,443 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRLF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,222,367 - 59,233,720 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1259,222,551 - 59,233,723 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,069,084 - 59,075,048 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRLF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,061,289 - 17,074,930 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,061,621 - 17,074,794 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660742,261,781 - 2,275,479 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crlf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,752,779 - 1,762,244 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249081,752,773 - 1,762,272 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Crlf1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11312,747,605 - 12,758,791 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Crlf1
40 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:35
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000060097
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161574800625801629Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)161627818427244292Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat

Markers in Region
RH128982  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,924,775 - 18,924,931 (+)MAPPERmRatBN7.2
Rnor_6.01620,675,096 - 20,675,251NCBIRnor6.0
Rnor_5.01620,530,575 - 20,530,730UniSTSRnor5.0
RGSC_v3.41619,431,526 - 19,431,681UniSTSRGSC3.4
Celera1619,116,152 - 19,116,307UniSTS
RH 3.4 Map16214.42UniSTS
Cytogenetic Map16p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 65 146 63 62 31 34 31 6 251 132 11 125 64 92 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000060097   ⟹   ENSRNOP00000056846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1618,957,956 - 18,969,970 (-)Ensembl
mRatBN7.2 Ensembl1618,924,722 - 18,935,997 (-)Ensembl
Rnor_6.0 Ensembl1620,675,042 - 20,686,317 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000152774   ⟹   ENSRNOP00000108067
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1618,957,956 - 18,969,970 (-)Ensembl
RefSeq Acc Id: NM_001106074   ⟹   NP_001099544
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,695 - 18,969,970 (-)NCBI
mRatBN7.21618,924,722 - 18,935,997 (-)NCBI
Rnor_6.01620,675,042 - 20,686,317 (-)NCBI
Rnor_5.01620,530,521 - 20,541,831 (-)NCBI
RGSC_v3.41619,431,472 - 19,442,747 (-)RGD
Celera1619,116,098 - 19,127,373 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252872   ⟹   XP_006252934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,024 (-)NCBI
mRatBN7.21618,924,733 - 18,936,047 (-)NCBI
Rnor_6.01620,675,052 - 20,686,365 (-)NCBI
Rnor_5.01620,530,521 - 20,541,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252874   ⟹   XP_006252936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,024 (-)NCBI
mRatBN7.21618,924,733 - 18,936,048 (-)NCBI
Rnor_6.01620,675,052 - 20,686,365 (-)NCBI
Rnor_5.01620,530,521 - 20,541,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094330   ⟹   XP_038950258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,026 (-)NCBI
mRatBN7.21618,924,733 - 18,936,049 (-)NCBI
RefSeq Acc Id: XM_039094331   ⟹   XP_038950259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,025 (-)NCBI
mRatBN7.21618,924,733 - 18,936,048 (-)NCBI
RefSeq Acc Id: XM_039094332   ⟹   XP_038950260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,960,134 - 18,970,026 (-)NCBI
mRatBN7.21618,926,161 - 18,936,049 (-)NCBI
RefSeq Acc Id: NP_001099544   ⟸   NM_001106074
- Peptide Label: precursor
- UniProtKB: A6KA48 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252934   ⟸   XM_006252872
- Peptide Label: isoform X3
- UniProtKB: D3ZIV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252936   ⟸   XM_006252874
- Peptide Label: isoform X4
- Sequence:
Ensembl Acc Id: ENSRNOP00000056846   ⟸   ENSRNOT00000060097
RefSeq Acc Id: XP_038950258   ⟸   XM_039094330
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038950259   ⟸   XM_039094331
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038950260   ⟸   XM_039094332
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000108067   ⟸   ENSRNOT00000152774
Protein Domains
Fibronectin type-III

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIV9-F1-model_v2 AlphaFold D3ZIV9 1-425 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700031
Promoter ID:EPDNEW_R10553
Type:multiple initiation site
Name:Crlf1_1
Description:cytokine receptor-like factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,686,325 - 20,686,385EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311371 AgrOrtholog
BioCyc Gene G2FUF-11782 BioCyc
Ensembl Genes ENSRNOG00000020030 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060097 ENTREZGENE
  ENSRNOT00000060097.4 UniProtKB/TrEMBL
  ENSRNOT00000152774 ENTREZGENE
  ENSRNOT00000152774.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Fibronectin_type3 UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Growth/epo_recpt_lig-bind UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Type-I_Cytokine_Rcpt UniProtKB/TrEMBL
KEGG Report rno:290655 UniProtKB/TrEMBL
NCBI Gene 290655 ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  CYTOKINE RECEPTOR-LIKE FACTOR 1 UniProtKB/TrEMBL
Pfam EpoR_lig-bind UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
PhenoGen Crlf1 PhenoGen
PROSITE FN3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020030 RatGTEx
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0ABK0LUY1_RAT UniProtKB/TrEMBL
  A6KA48 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIV9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Crlf1  cytokine receptor-like factor 1   Crlf1_predicted  cytokine receptor-like factor 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Crlf1_predicted  cytokine receptor-like factor 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED