Ltn1 (listerin E3 ubiquitin protein ligase 1) - Rat Genome Database

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Gene: Ltn1 (listerin E3 ubiquitin protein ligase 1) Rattus norvegicus
Analyze
Symbol: Ltn1
Name: listerin E3 ubiquitin protein ligase 1
RGD ID: 1311238
Description: Predicted to enable ribosomal large subunit binding activity and ubiquitin protein ligase activity. Predicted to be involved in protein autoubiquitination; rescue of stalled ribosome; and ribosome-associated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of RQC complex. Predicted to be active in cytosolic ribosome. Orthologous to human LTN1 (listerin E3 ubiquitin protein ligase 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase listerin; LOC288308; ring finger protein 160; Rnf160; Zfp294; zinc finger protein 294; Znf294
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81140,090,169 - 40,147,159 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1140,090,169 - 40,147,303 (-)EnsemblGRCr8
mRatBN7.21126,603,903 - 26,660,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1126,603,903 - 26,660,886 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1135,301,730 - 35,358,731 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01128,001,977 - 28,058,974 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01127,190,910 - 27,247,908 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,023,328 - 27,080,575 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,022,986 - 27,080,701 (-)Ensemblrn6Rnor6.0
Rnor_5.01130,648,567 - 30,706,023 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41127,126,258 - 27,184,111 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1126,356,355 - 26,413,197 (-)NCBICelera
RGSC_v3.11127,126,258 - 27,134,341 (-)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(S)-nicotine  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
6-propyl-2-thiouracil  (EXP)
alpha-phellandrene  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcium silicate  (ISO)
celastrol  (ISO)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chlorpyrifos  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
fenofibrate  (EXP)
fulvestrant  (ISO)
gedunin  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycerol  (ISO)
ifosfamide  (ISO)
metformin  (EXP)
methapyrilene  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
myricetin  (ISO)
nicotine  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propane-1,2-diol  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA,IEA,ISO)
cytosolic ribosome  (IEA,ISO)
RQC complex  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:19196968  


Genomics

Comparative Map Data
Ltn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81140,090,169 - 40,147,159 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1140,090,169 - 40,147,303 (-)EnsemblGRCr8
mRatBN7.21126,603,903 - 26,660,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1126,603,903 - 26,660,886 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1135,301,730 - 35,358,731 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01128,001,977 - 28,058,974 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01127,190,910 - 27,247,908 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,023,328 - 27,080,575 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,022,986 - 27,080,701 (-)Ensemblrn6Rnor6.0
Rnor_5.01130,648,567 - 30,706,023 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41127,126,258 - 27,184,111 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1126,356,355 - 26,413,197 (-)NCBICelera
RGSC_v3.11127,126,258 - 27,134,341 (-)NCBI
Cytogenetic Map11q11NCBI
LTN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382128,928,144 - 28,992,877 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2128,928,144 - 28,992,956 (-)Ensemblhg38GRCh38
GRCh372130,300,466 - 30,365,198 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362129,222,337 - 29,287,095 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342129,222,336 - 29,287,095NCBI
Celera2115,483,199 - 15,548,010 (-)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2115,705,158 - 15,769,951 (-)NCBIHuRef
CHM1_12129,862,811 - 29,927,624 (-)NCBICHM1_1
T2T-CHM13v2.02127,290,835 - 27,355,596 (-)NCBIT2T-CHM13v2.0
Ltn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391687,173,539 - 87,229,504 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1687,173,539 - 87,229,500 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381687,376,651 - 87,432,619 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1687,376,651 - 87,432,612 (-)Ensemblmm10GRCm38
MGSCv371687,376,896 - 87,432,851 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361687,265,847 - 87,321,802 (-)NCBIMGSCv36mm8
MGSCv361688,001,029 - 88,057,566 (-)NCBIMGSCv36mm8
Celera1687,558,856 - 87,624,942 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1649.52NCBI
Ltn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540728,301,636 - 28,352,797 (-)Ensembl
ChiLan1.0NW_00495540728,303,598 - 28,352,797 (-)NCBIChiLan1.0ChiLan1.0
LTN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22225,109,514 - 25,174,624 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12119,968,137 - 20,033,245 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02115,359,090 - 15,424,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12128,747,271 - 28,812,744 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2128,749,584 - 28,812,734 (-)EnsemblpanPan2panpan1.1
LTN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13123,942,493 - 24,008,787 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3123,944,611 - 24,008,917 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3123,935,054 - 24,002,104 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03124,054,956 - 24,122,763 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3124,054,957 - 24,122,660 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13124,006,096 - 24,073,139 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03124,007,941 - 24,074,805 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03124,479,423 - 24,546,297 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ltn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497124,406,797 - 24,453,685 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650013,014,102 - 13,061,699 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493650013,014,102 - 13,061,695 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LTN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13192,295,766 - 192,358,717 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113192,295,764 - 192,358,762 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213202,598,643 - 202,660,954 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LTN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1263,226,810 - 63,291,646 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl263,226,862 - 63,293,507 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660715,812,025 - 5,879,459 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ltn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474516,936,987 - 16,988,519 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474516,939,183 - 16,988,438 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ltn1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1456,425,693 - 56,480,135 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ltn1
783 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:275
Count of miRNA genes:125
Interacting mature miRNAs:150
Transcripts:ENSRNOT00000002180, ENSRNOT00000073948
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11381815448818154Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
RH129651  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21126,603,661 - 26,603,873 (+)MAPPERmRatBN7.2
Rnor_6.01127,023,087 - 27,023,298NCBIRnor6.0
Rnor_5.01130,648,326 - 30,648,537UniSTSRnor5.0
RGSC_v3.41127,126,017 - 27,126,228UniSTSRGSC3.4
Celera1126,356,114 - 26,356,325UniSTS
RH 3.4 Map11123.8UniSTS
Cytogenetic Map11q11UniSTS
RH144456  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21126,604,075 - 26,604,229 (+)MAPPERmRatBN7.2
Rnor_6.01127,023,501 - 27,023,654NCBIRnor6.0
Rnor_5.01130,648,740 - 30,648,893UniSTSRnor5.0
RGSC_v3.41127,126,431 - 27,126,584UniSTSRGSC3.4
Celera1126,356,528 - 26,356,681UniSTS
RH 3.4 Map11134.5UniSTS
Cytogenetic Map11q11UniSTS
BE112989  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21126,674,987 - 26,675,149 (+)MAPPERmRatBN7.2
Rnor_6.01127,094,808 - 27,094,969NCBIRnor6.0
Rnor_5.01130,720,256 - 30,720,417UniSTSRnor5.0
Rnor_5.01130,694,048 - 30,694,209UniSTSRnor5.0
RGSC_v3.41127,198,344 - 27,198,505UniSTSRGSC3.4
Celera1126,427,434 - 26,427,595UniSTS
RH 3.4 Map11135.7UniSTS
Cytogenetic Map11q11UniSTS
BI281238  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21126,604,016 - 26,604,189 (+)MAPPERmRatBN7.2
Rnor_6.01127,023,442 - 27,023,614NCBIRnor6.0
Rnor_5.01130,648,681 - 30,648,853UniSTSRnor5.0
RGSC_v3.41127,126,372 - 27,126,544UniSTSRGSC3.4
Celera1126,356,469 - 26,356,641UniSTS
RH 3.4 Map11136.6UniSTS
Cytogenetic Map11q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002180   ⟹   ENSRNOP00000002180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1140,090,169 - 40,147,303 (-)Ensembl
mRatBN7.2 Ensembl1126,603,903 - 26,660,886 (-)Ensembl
Rnor_6.0 Ensembl1127,022,986 - 27,080,701 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000073948   ⟹   ENSRNOP00000065249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1126,604,989 - 26,612,013 (-)Ensembl
Rnor_6.0 Ensembl1127,023,329 - 27,031,407 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110244   ⟹   ENSRNOP00000087423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1140,122,571 - 40,147,303 (-)Ensembl
mRatBN7.2 Ensembl1126,604,975 - 26,660,886 (-)Ensembl
RefSeq Acc Id: NM_001024235   ⟹   NP_001019406
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81140,090,169 - 40,147,011 (-)NCBI
mRatBN7.21126,603,903 - 26,660,750 (-)NCBI
Rnor_6.01127,023,328 - 27,080,575 (-)NCBI
Rnor_5.01130,648,567 - 30,706,023 (-)NCBI
RGSC_v3.41127,126,258 - 27,184,111 (-)RGD
Celera1126,356,355 - 26,413,197 (-)RGD
Sequence:
RefSeq Acc Id: XR_005491012
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81140,112,329 - 40,147,159 (-)NCBI
mRatBN7.21126,626,000 - 26,660,871 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001019406 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH86523 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002180
  ENSRNOP00000002180.6
  ENSRNOP00000087423.2
RefSeq Acc Id: NP_001019406   ⟸   NM_001024235
- UniProtKB: F1M9Q3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002180   ⟸   ENSRNOT00000002180
Ensembl Acc Id: ENSRNOP00000065249   ⟸   ENSRNOT00000073948
Ensembl Acc Id: ENSRNOP00000087423   ⟸   ENSRNOT00000110244
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M9Q3-F1-model_v2 AlphaFold F1M9Q3 1-1798 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698026
Promoter ID:EPDNEW_R8544
Type:initiation region
Name:Ltn1_1
Description:listerin E3 ubiquitin protein ligase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R8545  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01127,031,420 - 27,031,480EPDNEW
RGD ID:13698021
Promoter ID:EPDNEW_R8545
Type:multiple initiation site
Name:Ltn1_2
Description:listerin E3 ubiquitin protein ligase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R8544  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01127,080,644 - 27,080,704EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311238 AgrOrtholog
BioCyc Gene G2FUF-22056 BioCyc
Ensembl Genes ENSRNOG00000001602 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002180 ENTREZGENE
  ENSRNOT00000002180.9 UniProtKB/TrEMBL
  ENSRNOT00000110244.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  LTN1/Rkr1 UniProtKB/TrEMBL
  LTN1_E3_ligase_6th UniProtKB/TrEMBL
  LTN1_HEAT_5th UniProtKB/TrEMBL
  Ltn1_N UniProtKB/TrEMBL
  LTN1_UBC UniProtKB/TrEMBL
  RING-CH-C4HC3_LTN1 UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING-CH UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene 288308 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE LISTERIN UniProtKB/TrEMBL
  PTHR12389 UniProtKB/TrEMBL
Pfam Ltn1_1st UniProtKB/TrEMBL
  LTN1_E3_ligase_5th UniProtKB/TrEMBL
  LTN1_E3_ligase_6th UniProtKB/TrEMBL
  UBC_like UniProtKB/TrEMBL
  zf-RING_2 UniProtKB/TrEMBL
PhenoGen Ltn1 PhenoGen
PROSITE ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001602 RatGTEx
SMART RINGv UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
UniProt A0A8I6GF45_RAT UniProtKB/TrEMBL
  F1M9Q3 ENTREZGENE, UniProtKB/TrEMBL
  Q5RJS4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Ltn1  listerin E3 ubiquitin protein ligase 1  Rnf160  ring finger protein 160  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 Rnf160  ring finger protein 160  Znf294  zinc finger protein 294  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Znf294  zinc finger protein 294  Zfp294  zinc finger protein 294  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Zfp294  zinc finger protein 294  Zfp294_predicted  zinc finger protein 294 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Zfp294_predicted  zinc finger protein 294 (predicted)      Symbol and Name status set to approved 70820 APPROVED