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Gene: Exd2 (exonuclease 3'-5' domain containing 2) Rattus norvegicus

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Symbol:

Exd2

Name:

exonuclease 3'-5' domain containing 2

RGD ID:

1311087

Description:

Predicted to enable 3'-5' exonuclease activity; metal ion binding activity; and protein homodimerization activity. Predicted to be involved in DNA double-strand break processing; double-strand break repair via homologous recombination; and replication fork processing. Predicted to be located in mitochondrial outer membrane and site of DNA damage. Predicted to be active in cytoplasm and nucleus. Orthologous to human EXD2 (exonuclease 3'-5' domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Exdl2; exonuclease 3''-5'' domain-like 2; exonuclease 3'-5' domain-containing protein 2; LOC362759; RGD1311087; similar to expressed sequence C85658

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EXD2 (exonuclease 3'-5' domain containing 2)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Exd2 (exonuclease 3'-5' domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Exd2 (exonuclease 3'-5' domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EXD2 (exonuclease 3'-5' domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EXD2 (exonuclease 3'-5' domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Exd2 (exonuclease 3'-5' domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EXD2 (exonuclease 3'-5' domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EXD2 (exonuclease 3'-5' domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Exd2 (exonuclease 3'-5' domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Exd2 (exonuclease 3'-5' domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MCEE (methylmalonyl-CoA epimerase)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	EXD2 (exonuclease 3'-5' domain containing 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Exd2 (exonuclease 3'-5' domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	exd2 (exonuclease 3'-5' domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Exd2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Exd2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	exd2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	exd2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	105,847,931 - 105,881,780 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	105,848,305 - 105,883,665 (+)	Ensembl				GRCr8
mRatBN7.2	6	100,116,867 - 100,150,452 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	100,116,867 - 100,150,442 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	100,282,295 - 100,316,178 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	100,581,990 - 100,615,873 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	99,957,060 - 99,990,674 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	104,017,620 - 104,051,442 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	104,017,607 - 104,051,446 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	112,192,441 - 112,226,159 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	104,231,115 - 104,265,354 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	97,974,785 - 98,008,358 (+)	NCBI		Celera
RGSC_v3.1	6	104,234,693 - 104,268,073 (+)	NCBI
Cytogenetic Map	6	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

acrolein (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

choline (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

flutamide (EXP)

folic acid (ISO)

inulin (ISO)

L-methionine (ISO)

lead(0) (ISO)

methidathion (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

resveratrol (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

testosterone (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

torcetrapib (ISO)

tributylstannane (EXP)

triphenyl phosphate (ISO)

trovafloxacin (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA double-strand break processing (ISO)

double-strand break repair (ISO)

double-strand break repair via homologous recombination (ISO)

nucleobase-containing compound metabolic process (IEA)

replication fork processing (ISO)

Cellular Component

cytoplasm (IBA)

mitochondrial outer membrane (ISO)

mitochondrion (ISO)

nucleus (IBA)

site of DNA damage (ISO)

Molecular Function

3'-5' exonuclease activity (IBA,IEA,ISO)

3'-5'-DNA exonuclease activity (ISO)

3'-5'-RNA exonuclease activity (ISO)

exonuclease activity (IEA)

hydrolase activity (IEA)

magnesium ion binding (ISO)

manganese ion binding (ISO)

nuclease activity (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

protein homodimerization activity (ISO)

single-stranded DNA 3'-5' DNA exonuclease activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:22871113	PMID:26807646	PMID:29599527	PMID:31127291	PMID:31255466

Genomics

Comparative Map Data

Exd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	105,847,931 - 105,881,780 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	105,848,305 - 105,883,665 (+)	Ensembl				GRCr8
mRatBN7.2	6	100,116,867 - 100,150,452 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	100,116,867 - 100,150,442 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	100,282,295 - 100,316,178 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	100,581,990 - 100,615,873 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	99,957,060 - 99,990,674 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	104,017,620 - 104,051,442 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	104,017,607 - 104,051,446 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	112,192,441 - 112,226,159 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	104,231,115 - 104,265,354 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	97,974,785 - 98,008,358 (+)	NCBI		Celera
RGSC_v3.1	6	104,234,693 - 104,268,073 (+)	NCBI
Cytogenetic Map	6	q24	NCBI

EXD2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	69,191,498 - 69,244,018 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	69,191,498 - 69,244,020 (+)	Ensembl			hg38	GRCh38
GRCh37	14	69,658,215 - 69,710,735 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	68,746,231 - 68,778,825 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	68,746,230 - 68,778,825	NCBI
Celera	14	49,722,349 - 49,774,877 (+)	NCBI		Celera
Cytogenetic Map	14	q24.1	NCBI
HuRef	14	49,828,887 - 49,881,419 (+)	NCBI		HuRef
CHM1_1	14	69,596,430 - 69,648,894 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	63,404,602 - 63,457,085 (+)	NCBI		T2T-CHM13v2.0

Exd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	80,509,869 - 80,544,909 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	80,509,869 - 80,547,001 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	12	80,463,095 - 80,498,135 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	80,463,095 - 80,500,227 (+)	Ensembl			mm10	GRCm38
MGSCv37	12	81,564,082 - 81,599,122 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	12	81,394,842 - 81,416,970 (+)	NCBI		MGSCv36	mm8
Celera	12	81,928,182 - 81,963,154 (+)	NCBI		Celera
Cytogenetic Map	12	C3	NCBI
cM Map	12	36.73	NCBI

Exd2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955466	1,110,395 - 1,169,242 (-)	Ensembl
ChiLan1.0	NW_004955466	1,114,299 - 1,169,124 (-)	NCBI	ChiLan1.0	ChiLan1.0

EXD2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	70,313,041 - 70,366,036 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	69,527,465 - 69,582,549 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	49,783,072 - 49,835,645 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	68,656,455 - 68,708,773 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	68,656,669 - 68,707,834 (+)	Ensembl			panPan2	panpan1.1

EXD2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	43,028,537 - 43,082,038 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	43,042,563 - 43,187,969 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	42,717,745 - 42,773,001 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	43,257,837 - 43,313,332 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	43,257,911 - 43,316,242 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	42,872,325 - 42,927,784 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	42,946,902 - 43,002,520 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	43,306,406 - 43,361,842 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Exd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	61,711,892 - 61,758,994 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936495	12,432,731 - 12,479,876 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936495	12,432,752 - 12,479,807 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EXD2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	92,848,032 - 92,913,771 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	92,847,958 - 92,909,044 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	99,038,091 - 99,131,917 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EXD2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	46,431,309 - 46,480,500 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	46,444,282 - 46,482,845 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666053	34,655,161 - 34,706,362 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Exd2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	31,819,440 - 31,866,937 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624734	31,822,927 - 31,866,678 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Exd2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	94,680,292 - 94,714,476 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Exd2
239 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	495
Count of miRNA genes:	243
Interacting mature miRNAs:	290
Transcripts:	ENSRNOT00000033378
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293088	Iddm28	Insulin dependent diabetes mellitus QTL 28	5.21		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	68767270	135411972	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	88019181	136741135	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	84490437	129490437	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	101593607	138161926	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	99437079	125323237	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	86494122	112380234	Rat
1331722	Thshl1	Thyroid stimulating hormone level QTL 1	11.7	0.0001	blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	6	99708426	112483760	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	71278722	116278722	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	64367996	109367996	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	93560258	136550638	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	90871046	135871046	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	98944780	143944780	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	100704576	136029228	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	79198463	144254945	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	46050607	116278722	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	93778632	138778632	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2293837	Kiddil1	Kidney dilation QTL 1	3.7		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
2293842	Kiddil3	Kidney dilation QTL 3	4.3		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	90871046	135871046	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	93560258	136550638	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	78204640	123204640	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	93560258	136550638	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	76937178	121937178	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	101593607	146593607	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001434008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001434009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240286	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033378 ⟹ ENSRNOP00000030862

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	105,848,305 - 105,883,665 (+)	Ensembl
mRatBN7.2 Ensembl	6	100,116,978 - 100,150,442 (+)	Ensembl
Rnor_6.0 Ensembl	6	104,017,607 - 104,051,446 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094099 ⟹ ENSRNOP00000079247

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	100,116,867 - 100,146,009 (+)	Ensembl

RefSeq Acc Id:

NM_001108715 ⟹ NP_001102185

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	105,848,202 - 105,881,777 (+)	NCBI
mRatBN7.2	6	100,116,867 - 100,150,444 (+)	NCBI
Rnor_6.0	6	104,017,889 - 104,051,434 (+)	NCBI
Rnor_5.0	6	112,192,441 - 112,226,159 (+)	NCBI
RGSC_v3.4	6	104,231,115 - 104,265,354 (+)	RGD
Celera	6	97,974,785 - 98,008,358 (+)	RGD

Sequence:

show sequence

ATGGCGCGGCCCACAGGCACACACCACGGGGGTTATATCCTCCTGGCCAGCCACTGGGCCGGAA
GTGGCTACGGCTTTTATGCATCCGGGTGGATTGTGGGTCAGTGAAATGCATTCCTAAACAGTGA
AAGGCTAAAGATGTCTAGACAGAATTTACTGGCTTTGACAGTGACCACCCTTTTGGGTGTGGCC
ATGGGGGGATTTGTCCTGTGGAAAGGCATCCAGCGTAAATGGAGTAAGACAAGCAGAGTGATGC
AGCCACAGCTGCAGCCACAACCACAGCAGCAGCAGCAGCCGCAGCCACAGCAGCAACAGCAGCC
GCCACAGCAGGAGCAGCAGAAGCAGCAAGTGCCCGGTGCGAGGGAGTGGCCCCCTCCAGAAGAT
GACCAGTTACCCTTTGGTGCCCTGAGAACACCCAGAGCTTCATGGGAGGAGAGGATACTCCAGG
CAGAGGTGGTGACAGTTTCTCAGGAGGCAGAGTGGAATCAAATCCAGCCCTTTCTTAAAAGAGA
GTTGGAAGATTTTCCAGTACTTGGAATTGACTGTGAATGGGTGAATTTGGAAGGCAAAGCCAGT
CCTTTGTCACTCCTACAGATGGCTTCCCCAAGTGGCTTCTGTGCATTGGTTCGCTTGCCCAGGC
TGATATATGGAGGCAAAACACTACCCAGAACACTTTTGGACATATTGGCAGATGGCACTATCTT
GAAAGTAGGAGTGGGATGCTCAGAAGATGCCAACAAACTTCTACAGGATTATGGCCTCATTGTT
AGGGGATGTCTGGACCTCCGCTACCTAGCCATGAAGCAGGGAAACAGTGTACTCTGTAATGGGC
TTAGCCTGAAATCACTTGCTGAGACTCTTTTGAACTTCCCACTTGACAAGTCCCTTCTACTTCG
TTGCAGCAACTGGGATGCTGAGAATCTTACTGAAGACCAGGTAACTTATGCTGCCAGGGATGCA
CAGATTTCAGTGGCTCTCTTTCTCCATCTTCTTGGATACCCTTTCTCTAGAAATTCCTATGAAG
AGGAAAACAATGGCCAAATCAACTGGCAAAAAGTCTTGGAGAAATGCAGGGATATGGTAGACAT
CCCATTCCGAAGCAAAGGACTTGCCCGGCTGGGTGAAGAGATTAATGGGGAAGCACTGGAATCG
CAGCAGAAGCCAAGAAATAGGAAGGCTAGGACTGATGGAATGGTGCCAGGCAGCAACCAAGGGA
GAGACCCCAGGAAGCATAAGAGGAAGCCCCTGGGGGTGGGCTATTCTGCCAGAAAGTCACCTCT
CTATGATAACTGCTTTCTCCAAGCTCCTGATGGACAGCCCTTGTGCACCTGTGACCGGAGGAAA
GCTCAGTGGTACCTGGACAAAGGCATTGGAGAGCTGGTGAGTAAAGAACCCTTTGTGGTCAGGC
TACAGTTTGAACCTGCAGGAAGACCTGAATCCCCGGGAGATTATTACTTGATGGTTAAAGAGAA
CCTGTGTGTTGTCTGTGGCAAGACAGATACCTACATCCGGAAAAACATAATTCCACATGAGTAC
CGCAAGCACTTCCCCATTGAGATGAAGGACCACAACTCCCATGATGTGCTGCTGCTCTGCACCT
CCTGCCATGCCATCTCTAACTACTATGACAACCATCTGAAGCAGCAGCTGGCCAAGGAGTTCCA
GGCCCCCATTGGCTCAGAGGAGGGCCTGCGCCTGCTGGAAGACCTAGAGCGTAGGCAGGTGCGT
TCCGGAGCCAGAGCCCTGCTCAATGCGGAGAGCCTACCTGCCCATCGGAAAGAAGAGTTGCTGC
ATGCACTCAGGGAGTTTTACAACACAGACATTGTTACAGAGGAGATGCTCCAAGAGGCGGCCAG
CCTGGAGACCAGGATATACAATGAAAGTTATATTCCTCATGGGCTAAAGGTGGTACAGCGGCAC
ACGGAGGGTGGGCTGCGCTCCCTCATGCAGCTGGAGAGCCGCTGGCGTCAGCACTTCCTGGACT
CCATGCAGCCTAAGCACCTGCCCCAGCAGTGGTCAGTGGACCATAACCATCAGAAGCTGCTCCG
AAAGTATGGGGACGACCTTCCCATCAAGCTGTCATGAGTACTGCTTCCTGCAGATCAGGACAGG
CGGGAAGCAGGGGCCTCCTGCTGTTAATGTTCTTAACGGTCGAAGCCCTGGTAACTCAGCTCAG
AATGCTAACCTACACTGATCCCCAGGTCCTTCTGATGGAGCAAGGCTGTTGTTTAAAGGGGAGC
TTATGGTTTTGAATTTTAGTTGAGGAGTCTATTCTTTTCTCCTCCTCTCTCTCCTATTTTTCTG
TGCAAAAGAAGCTTGGCCTTCATTTTCACACTCCCTCTCTGCTTGTCCTGTTAAGAGGGAGAAG
TCTTCTCTAAAATAACTTGTCGGGCCCTGGGAAGATGTTTATAATTCTCTTTGCTGCCTTGGTT
TTTCCAGGCCTGAGAGAAAACTTTCTCCACAGTTGAAGAAGTGACCCACAAGTCACAGTCATAT
TCCCAGCTCAGCCTCACACTTTTAATCTTCCTTGCTCTCCCATATGCATTTGTTTGGGGCCCAT
TCCAACTGTATTACTTGGATTTATTTTACATGCTTGAAAATGTTACCACTTAACACATACAGGA
CCAAAGTCCAGCTTGCTATGGGCTCCTTAACATCACAGGGGAAGTCCTTTTCTGGAAATGAGTA
CTCAGCTGGCTGTGCTGACAAGCACTGACCCTTTCCCAGGAGAGCTGTGGTACATTGTTCAGCC
TCTCCTCTGCTTGCATGTCTCTTGTCCTGCTCTGAGGACCATCATCTCTCCGCACCCGCTCCCT
TCAGTGTTCATGTTCCATTGCGTTTGCAGTACTGATCTCTCCTTAGTATTTAAGTCACTCCCAT
AGCCCTTTGGCCAGGTTTCAGAGTGAGGACTTCACCTCCCCTAAAGCCTGAGACACTGAAATTA
ACTGATACAATAGAAGTTTAAAAGGGTAATGCTTCACCTTTCAAAATGTTAGACTACTACTTTG
AGTATGAAATCAATTTATTAGCAATTAGTATTTTTTCTAAACTATTAGGAAAACTTTCTTATTT
TATAAGATCTTAACAAGCTTGAAAAGAATTTTATGGCCAGAATCCAACAAGAGTTCTATTTTGG
AATTGTACCCAAGTTGGTTATAACTGATCTGACATTGATAAATAAAACAACTTCAAAGCAC

hide sequence

RefSeq Acc Id:

XM_006240286 ⟹ XP_006240348

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	105,847,931 - 105,881,780 (+)	NCBI
mRatBN7.2	6	100,116,901 - 100,150,452 (+)	NCBI
Rnor_6.0	6	104,017,620 - 104,051,442 (+)	NCBI
Rnor_5.0	6	112,192,441 - 112,226,159 (+)	NCBI

Sequence:

show sequence

TAAACAGTTTCTTTATTTTCTCGCTCGAATATAAGAAAATTAATGTAATAGAGAAACGCTATCC
GGGTTAAAAGAGAAAATGATATGTCTTATGTTGCATTTGTGAGTGAAAGTTCAGTAGGCTTCTT
CCTTCAAAGCCAAAACCAGAAGACCAAGCGCCATCTCAGAAAACAGCACTTTTCCGAAGTCATT
AAGTCTTCATAATTTCAACCCATCTTTTAACCGAGAACCTGGGGAGGTAACGGCTGTCCTAGCG
GCTTCCGTACAAAATGGCGCGGCCCACAGGCACACACCACGGGGGTTATATCCTCCTGGCCAGC
CACTGGGCCGGAAGTGGCTACGGCTTTTATGCATCCGGGTGGGTGCGTCCTGGCCGCCGCGGGG
GTTCCAGCTTGTCAGCGTGGGGTGCCGCAGGTGTTCGGTGGAGGCTGGAGGCCGCAGATTGTGG
GTCAGTGAAATGCATTCCTAAACAGTGAAAGGCTAAAGATGTCTAGACAGAATTTACTGGCTTT
GACAGTGACCACCCTTTTGGGTGTGGCCATGGGGGGATTTGTCCTGTGGAAAGGCATCCAGCGT
AAATGGAGTAAGACAAGCAGAGTGATGCAGCCACAGCTGCAGCCACAACCACAGCAGCAGCAGC
AGCCGCAGCCACAGCAGCAACAGCAGCCGCCACAGCAGGAGCAGCAGAAGCAGCAAGTGCCCGG
TGCGAGGGAGTGGCCCCCTCCAGAAGATGACCAGTTACCCTTTGGTGCCCTGAGAACACCCAGA
GCTTCATGGGAGGAGAGGATACTCCAGGCAGAGGTGGTGACAGTTTCTCAGGAGGCAGAGTGGA
ATCAAATCCAGCCCTTTCTTAAAAGAGAGTTGGAAGATTTTCCAGTACTTGGAATTGACTGTGA
ATGGGTGAATTTGGAAGGCAAAGCCAGTCCTTTGTCACTCCTACAGATGGCTTCCCCAAGTGGC
TTCTGTGCATTGGTTCGCTTGCCCAGGCTGATATATGGAGGCAAAACACTACCCAGAACACTTT
TGGACATATTGGCAGATGGCACTATCTTGAAAGTAGGAGTGGGATGCTCAGAAGATGCCAACAA
ACTTCTACAGGATTATGGCCTCATTGTTAGGGGATGTCTGGACCTCCGCTACCTAGCCATGAAG
CAGGGAAACAGTGTACTCTGTAATGGGCTTAGCCTGAAATCACTTGCTGAGACTCTTTTGAACT
TCCCACTTGACAAGTCCCTTCTACTTCGTTGCAGCAACTGGGATGCTGAGAATCTTACTGAAGA
CCAGGTAACTTATGCTGCCAGGGATGCACAGATTTCAGTGGCTCTCTTTCTCCATCTTCTTGGA
TACCCTTTCTCTAGAAATTCCTATGAAGAGGAAAACAATGGCCAAATCAACTGGCAAAAAGTCT
TGGAGAAATGCAGGGATATGGTAGACATCCCATTCCGAAGCAAAGGACTTGCCCGGCTGGGTGA
AGAGATTAATGGGGAAGCACTGGAATCGCAGCAGAAGCCAAGAAATAGGAAGGCTAGGACTGAT
GGAATGGTGCCAGGCAGCAACCAAGGGAGAGACCCCAGGAAGCATAAGAGGAAGCCCCTGGGGG
TGGGCTATTCTGCCAGAAAGTCACCTCTCTATGATAACTGCTTTCTCCAAGCTCCTGATGGACA
GCCCTTGTGCACCTGTGACCGGAGGAAAGCTCAGTGGTACCTGGACAAAGGCATTGGAGAGCTG
GTGAGTAAAGAACCCTTTGTGGTCAGGCTACAGTTTGAACCTGCAGGAAGACCTGAATCCCCGG
GAGATTATTACTTGATGGTTAAAGAGAACCTGTGTGTTGTCTGTGGCAAGACAGATACCTACAT
CCGGAAAAACATAATTCCACATGAGTACCGCAAGCACTTCCCCATTGAGATGAAGGACCACAAC
TCCCATGATGTGCTGCTGCTCTGCACCTCCTGCCATGCCATCTCTAACTACTATGACAACCATC
TGAAGCAGCAGCTGGCCAAGGAGTTCCAGGCCCCCATTGGCTCAGAGGAGGGCCTGCGCCTGCT
GGAAGACCTAGAGCGTAGGCAGGTGCGTTCCGGAGCCAGAGCCCTGCTCAATGCGGAGAGCCTA
CCTGCCCATCGGAAAGAAGAGTTGCTGCATGCACTCAGGGAGTTTTACAACACAGACATTGTTA
CAGAGGAGATGCTCCAAGAGGCGGCCAGCCTGGAGACCAGGATATACAATGAAAGTTATATTCC
TCATGGGCTAAAGGTGGTACAGCGGCACACGGAGGGTGGGCTGCGCTCCCTCATGCAGCTGGAG
AGCCGCTGGCGTCAGCACTTCCTGGACTCCATGCAGCCTAAGCACCTGCCCCAGCAGTGGTCAG
TGGACCATAACCATCAGAAGCTGCTCCGAAAGTATGGGGACGACCTTCCCATCAAGCTGTCATG
AGTACTGCTTCCTGCAGATCAGGACAGGCGGGAAGCAGGGGCCTCCTGCTGTTAATGTTCTTAA
CGGTCGAAGCCCTGGTAACTCAGCTCAGAATGCTAACCTACACTGATCCCCAGGTCCTTCTGAT
GGAGCAAGGCTGTTGTTTAAAGGGGAGCTTATGGTTTTGAATTTTAGTTGAGGAGTCTATTCTT
TTCTCCTCCTCTCTCTCCTATTTTTCTGTGCAAAAGAAGCTTGGCCTTCATTTTCACACTCCCT
CTCTGCTTGTCCTGTTAAGAGGGAGAAGTCTTCTCTAAAATAACTTGTCGGGCCCTGGGAAGAT
GTTTATAATTCTCTTTGCTGCCTTGGTTTTTCCAGGCCTGAGAGAAAACTTTCTCCACAGTTGA
AGAAGTGACCCACAAGTCACAGTCATATTCCCAGCTCAGCCTCACACTTTTAATCTTCCTTGCT
CTCCCATATGCATTTGTTTGGGGCCCATTCCAACTGTATTACTTGGATTTATTTTACATGCTTG
AAAATGTTACCACTTAACACATACAGGACCAAAGTCCAGCTTGCTATGGGCTCCTTAACATCAC
AGGGGAAGTCCTTTTCTGGAAATGAGTACTCAGCTGGCTGTGCTGACAAGCACTGACCCTTTCC
CAGGAGAGCTGTGGTACATTGTTCAGCCTCTCCTCTGCTTGCATGTCTCTTGTCCTGCTCTGAG
GACCATCATCTCTCCGCACCCGCTCCCTTCAGTGTTCATGTTCCATTGCGTTTGCAGTACTGAT
CTCTCCTTAGTATTTAAGTCACTCCCATAGCCCTTTGGCCAGGTTTCAGAGTGAGGACTTCACC
TCCCCTAAAGCCTGAGACACTGAAATTAACTGATACAATAGAAGTTTAAAAGGGTAATGCTTCA
CCTTTCAAAATGTTAGACTACTACTTTGAGTATGAAATCAATTTATTAGCAATTAGTATTTTTT
CTAAACTATTAGGAAAACTTTCTTATTTTATAAGATCTTAACAAGCTTGAAAAGAATTTTATGG
CCAGAATCCAACAAGAGTTCTATTTTGGAATTGTACCCAAGTTGGTTATAACTGATCTGACATT
GATAAATAAAACAACTTCAAAGCACAAAGCTCA

hide sequence

RefSeq Acc Id:

XM_039112511 ⟹ XP_038968439

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	105,847,931 - 105,881,780 (+)	NCBI
mRatBN7.2	6	100,116,901 - 100,150,452 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102185	(Get FASTA)	NCBI Sequence Viewer
	NP_001420937	(Get FASTA)	NCBI Sequence Viewer
	NP_001420938	(Get FASTA)	NCBI Sequence Viewer
	XP_006240348	(Get FASTA)	NCBI Sequence Viewer
	XP_038968439	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66432	(Get FASTA)	NCBI Sequence Viewer
	EDL81378	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030862
	ENSRNOP00000030862.6

RefSeq Acc Id:

NP_001102185 ⟸ NM_001108715

- Sequence:

show sequence

MSRQNLLALTVTTLLGVAMGGFVLWKGIQRKWSKTSRVMQPQLQPQPQQQQQPQPQQQQQPPQQ
EQQKQQVPGAREWPPPEDDQLPFGALRTPRASWEERILQAEVVTVSQEAEWNQIQPFLKRELED
FPVLGIDCEWVNLEGKASPLSLLQMASPSGFCALVRLPRLIYGGKTLPRTLLDILADGTILKVG
VGCSEDANKLLQDYGLIVRGCLDLRYLAMKQGNSVLCNGLSLKSLAETLLNFPLDKSLLLRCSN
WDAENLTEDQVTYAARDAQISVALFLHLLGYPFSRNSYEEENNGQINWQKVLEKCRDMVDIPFR
SKGLARLGEEINGEALESQQKPRNRKARTDGMVPGSNQGRDPRKHKRKPLGVGYSARKSPLYDN
CFLQAPDGQPLCTCDRRKAQWYLDKGIGELVSKEPFVVRLQFEPAGRPESPGDYYLMVKENLCV
VCGKTDTYIRKNIIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPI
GSEEGLRLLEDLERRQVRSGARALLNAESLPAHRKEELLHALREFYNTDIVTEEMLQEAASLET
RIYNESYIPHGLKVVQRHTEGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNHQKLLRKYG
DDLPIKLS

hide sequence

RefSeq Acc Id:

XP_006240348 ⟸ XM_006240286

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSRQNLLALTVTTLLGVAMGGFVLWKGIQRKWSKTSRVMQPQLQPQPQQQQQPQPQQQQQPPQQ
EQQKQQVPGAREWPPPEDDQLPFGALRTPRASWEERILQAEVVTVSQEAEWNQIQPFLKRELED
FPVLGIDCEWVNLEGKASPLSLLQMASPSGFCALVRLPRLIYGGKTLPRTLLDILADGTILKVG
VGCSEDANKLLQDYGLIVRGCLDLRYLAMKQGNSVLCNGLSLKSLAETLLNFPLDKSLLLRCSN
WDAENLTEDQVTYAARDAQISVALFLHLLGYPFSRNSYEEENNGQINWQKVLEKCRDMVDIPFR
SKGLARLGEEINGEALESQQKPRNRKARTDGMVPGSNQGRDPRKHKRKPLGVGYSARKSPLYDN
CFLQAPDGQPLCTCDRRKAQWYLDKGIGELVSKEPFVVRLQFEPAGRPESPGDYYLMVKENLCV
VCGKTDTYIRKNIIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPI
GSEEGLRLLEDLERRQVRSGARALLNAESLPAHRKEELLHALREFYNTDIVTEEMLQEAASLET
RIYNESYIPHGLKVVQRHTEGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNHQKLLRKYG
DDLPIKLS

hide sequence

Ensembl Acc Id:

ENSRNOP00000030862 ⟸ ENSRNOT00000033378

RefSeq Acc Id:	XP_038968439 ⟸ XM_039112511
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000079247 ⟸ ENSRNOT00000094099

Protein Domains

3'-5' exonuclease

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B2GUW4-F1-model_v2	AlphaFold	B2GUW4	1-648	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311087	AgrOrtholog
BioCyc Gene	G2FUF-36912	BioCyc
Ensembl Genes	ENSRNOG00000027707	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000033378	ENTREZGENE
	ENSRNOT00000033378.7	UniProtKB/TrEMBL
Gene3D-CATH	3.30.420.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7135396	IMAGE-MGC_LOAD
InterPro	3-5_Exonuclease_domain	UniProtKB/TrEMBL
	3_5_exonuclease	UniProtKB/TrEMBL
	PolynucTfrase_RNaseH_fold	UniProtKB/TrEMBL
	RNaseH_sf	UniProtKB/TrEMBL
KEGG Report	rno:362759	UniProtKB/TrEMBL
MGC_CLONE	MGC:187466	IMAGE-MGC_LOAD
NCBI Gene	362759	ENTREZGENE
PANTHER	3-5 EXONUCLEASE	UniProtKB/TrEMBL
	EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
Pfam	3_5_exonuc	UniProtKB/TrEMBL
PhenoGen	Exd2	PhenoGen
RatGTEx	ENSRNOG00000027707	RatGTEx
SMART	35EXOc	UniProtKB/TrEMBL
Superfamily-SCOP	RNaseH_fold	UniProtKB/TrEMBL
UniProt	B2GUW4	ENTREZGENE, UniProtKB/TrEMBL
	F7FEI8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-03-24	Exd2	exonuclease 3'-5' domain containing 2	Exdl2	exonuclease 3''-5'' domain-like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Exdl2	exonuclease 3''-5'' domain-like 2	Exdl2_predicted	exonuclease 3''-5'' domain-like 2 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Exdl2_predicted	exonuclease 3''-5'' domain-like 2 (predicted)	RGD1311087_predicted	similar to expressed sequence C85658 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1311087_predicted	similar to expressed sequence C85658 (predicted)	LOC362759_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC362759_predicted	similar to expressed sequence C85658 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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