Ndufs5 (NADH:ubiquinone oxidoreductase subunit S5) - Rat Genome Database

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Gene: Ndufs5 (NADH:ubiquinone oxidoreductase subunit S5) Rattus norvegicus
Analyze
Symbol: Ndufs5 (Ensembl: Ndufs5-ps2)
Name: NADH:ubiquinone oxidoreductase subunit S5 (Ensembl:NADH:ubiquinone oxidoreductase subunit S5, pseudogene 2)
RGD ID: 1311081
Description: Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex I. Predicted to be active in mitochondrial inner membrane. Orthologous to human NDUFS5 (NADH:ubiquinone oxidoreductase subunit S5); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362588; NADH dehydrogenase (ubiquinone) Fe-S protein 5; NADH dehydrogenase (ubiquinone) Fe-S protein 5b; NADH dehydrogenase (ubiquinone) Fe-S protein 5b, 15kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 5; Ndufs5b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Ndufs5-ps1   Ndufs5-ps2  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85141,258,828 - 141,264,552 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2184,849,197 - 185,028,909 (+)EnsemblGRCr8
GRCr8 Ensembl14107,552,188 - 107,552,726 (-)EnsemblGRCr8
GRCr8 Ensembl5141,258,833 - 141,264,402 (-)EnsemblGRCr8
mRatBN7.25135,974,029 - 135,979,705 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,339,360 - 182,339,853 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl14103,351,386 - 103,351,706 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl5135,974,034 - 135,979,603 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5138,680,263 - 138,685,862 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05140,450,258 - 140,455,857 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05140,457,422 - 140,463,021 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd5140,899,053 - 140,904,628 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive5142,876,653 - 142,882,228 (-)NCBILyon_Normotensive
Lyon_Hypertensive5142,063,882 - 142,069,457 (-)NCBILyon_Hypertensive
F344_StmMcwi5135,620,668 - 135,626,239 (-)NCBIF344_StmMcwi
Rnor_6.05141,390,577 - 141,405,507 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5141,390,580 - 141,405,453 (-)Ensemblrn6Rnor6.0
Rnor_5.05145,178,499 - 145,196,014 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45143,017,421 - 143,023,425 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5134,511,122 - 134,516,696 (-)NCBICelera
RGSC_v3.15143,027,417 - 143,058,784 (-)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzbromarone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chloropicrin  (ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
hydralazine  (ISO)
isoniazide  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
lipopolysaccharide  (ISO)
methotrexate  (ISO)
methylparaben  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nitrates  (ISO)
omeprazole  (EXP)
osimertinib  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phlorizin  (ISO)
pirinixic acid  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
tolcapone  (EXP)
toluene  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8889548   PMID:11112787   PMID:12477932   PMID:12611891   PMID:14651853   PMID:16826196   PMID:18614015   PMID:27626371   PMID:28844695  


Genomics

Comparative Map Data
Ndufs5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85141,258,828 - 141,264,552 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2184,849,197 - 185,028,909 (+)EnsemblGRCr8
GRCr8 Ensembl14107,552,188 - 107,552,726 (-)EnsemblGRCr8
GRCr8 Ensembl5141,258,833 - 141,264,402 (-)EnsemblGRCr8
mRatBN7.25135,974,029 - 135,979,705 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,339,360 - 182,339,853 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl14103,351,386 - 103,351,706 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl5135,974,034 - 135,979,603 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5138,680,263 - 138,685,862 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05140,450,258 - 140,455,857 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05140,457,422 - 140,463,021 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd5140,899,053 - 140,904,628 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive5142,876,653 - 142,882,228 (-)NCBILyon_Normotensive
Lyon_Hypertensive5142,063,882 - 142,069,457 (-)NCBILyon_Hypertensive
F344_StmMcwi5135,620,668 - 135,626,239 (-)NCBIF344_StmMcwi
Rnor_6.05141,390,577 - 141,405,507 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5141,390,580 - 141,405,453 (-)Ensemblrn6Rnor6.0
Rnor_5.05145,178,499 - 145,196,014 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45143,017,421 - 143,023,425 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5134,511,122 - 134,516,696 (-)NCBICelera
RGSC_v3.15143,027,417 - 143,058,784 (-)NCBI
Cytogenetic Map5q36NCBI
NDUFS5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38139,026,350 - 39,034,615 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl139,026,318 - 39,034,636 (+)Ensemblhg38GRCh38
GRCh37139,492,022 - 39,500,287 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36139,264,593 - 39,272,874 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34139,161,098 - 39,169,379NCBI
Celera137,772,450 - 37,780,784 (+)NCBICelera
Cytogenetic Map1p34.3NCBI
HuRef137,611,448 - 37,619,691 (+)NCBIHuRef
CHM1_1139,607,376 - 39,615,715 (+)NCBICHM1_1
T2T-CHM13v2.0138,893,542 - 38,901,803 (+)NCBIT2T-CHM13v2.0
Ndufs5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394123,606,503 - 123,611,979 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4123,606,503 - 123,611,995 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384123,712,710 - 123,718,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4123,712,710 - 123,718,202 (-)Ensemblmm10GRCm38
MGSCv374123,389,953 - 123,395,429 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364123,215,013 - 123,220,489 (-)NCBIMGSCv36mm8
Celera4122,046,646 - 122,052,111 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.42NCBI
Ndufs5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545216,634,537 - 16,641,344 (+)Ensembl
ChiLan1.0NW_00495545216,634,537 - 16,641,344 (+)NCBIChiLan1.0ChiLan1.0
NDUFS5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21187,799,682 - 187,808,556 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11186,937,361 - 186,945,736 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0138,304,225 - 38,312,608 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1139,651,660 - 39,659,266 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl139,651,659 - 39,659,266 (+)EnsemblpanPan2panpan1.1
NDUFS5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1153,741,863 - 3,748,973 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl153,741,867 - 3,821,625 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha153,979,922 - 3,987,016 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0153,863,536 - 3,870,638 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl153,863,540 - 3,942,800 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1153,731,307 - 3,738,391 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0153,798,745 - 3,805,838 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0153,814,265 - 3,821,387 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ndufs5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505855,179,723 - 55,187,960 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647421,004,036 - 21,012,767 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647421,004,476 - 21,012,742 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFS5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl694,913,076 - 94,919,452 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1694,913,406 - 94,919,458 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2687,962,957 - 87,968,997 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFS5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603322,970,108 - 22,978,785 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufs5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476421,604,185 - 21,613,246 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476421,603,890 - 21,613,360 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ndufs5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1134,563,380 - 34,568,949 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ndufs5
13 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:105
Count of miRNA genes:74
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000036389, ENSRNOT00000042985
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5130678987145274255Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
7411722Strs6Sensitivity to stroke QTL 63.9cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)5140258140143398122Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
RH127820  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,989,348 - 135,989,561 (+)MAPPERmRatBN7.2
Rnor_6.05141,415,197 - 141,415,409NCBIRnor6.0
Rnor_5.05145,205,716 - 145,205,928UniSTSRnor5.0
Rnor_5.05145,193,168 - 145,193,380UniSTSRnor5.0
RGSC_v3.45143,033,169 - 143,033,381UniSTSRGSC3.4
Celera5134,526,433 - 134,526,645UniSTS
RH 3.4 Map5890.4UniSTS
Cytogenetic Map5q36UniSTS
RH130590  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,989,537 - 135,989,754 (+)MAPPERmRatBN7.2
Rnor_6.05141,415,386 - 141,415,602NCBIRnor6.0
Rnor_5.05145,205,905 - 145,206,121UniSTSRnor5.0
Rnor_5.05145,193,357 - 145,193,573UniSTSRnor5.0
RGSC_v3.45143,033,358 - 143,033,574UniSTSRGSC3.4
Celera5134,526,622 - 134,526,838UniSTS
RH 3.4 Map1546.9UniSTS
Cytogenetic Map5q36UniSTS
RH131908  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,988,650 - 135,988,832 (+)MAPPERmRatBN7.2
Rnor_6.05141,414,499 - 141,414,680NCBIRnor6.0
Rnor_5.05145,205,018 - 145,205,199UniSTSRnor5.0
Rnor_5.05145,192,470 - 145,192,651UniSTSRnor5.0
RGSC_v3.45143,032,471 - 143,032,652UniSTSRGSC3.4
Celera5134,525,735 - 134,525,916UniSTS
RH 3.4 Map5890.2UniSTS
Cytogenetic Map5q36UniSTS
RH80001  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,989,405 - 135,989,605 (+)MAPPERmRatBN7.2
Rnor_6.05141,415,254 - 141,415,453NCBIRnor6.0
Rnor_5.05145,205,773 - 145,205,972UniSTSRnor5.0
Rnor_5.05145,193,225 - 145,193,424UniSTSRnor5.0
RGSC_v3.45143,033,226 - 143,033,425UniSTSRGSC3.4
Celera5134,526,490 - 134,526,689UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
22 23 116 259 161 162 104 115 104 9 538 280 11 224 116 142 58 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000036389   ⟹   ENSRNOP00000037699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5141,258,833 - 141,264,402 (-)Ensembl
mRatBN7.2 Ensembl5135,974,034 - 135,979,603 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000042985   ⟹   ENSRNOP00000048968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2184,849,197 - 185,028,909 (+)Ensembl
mRatBN7.2 Ensembl2182,339,360 - 182,339,853 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083199   ⟹   ENSRNOP00000071076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl14107,552,188 - 107,552,726 (-)Ensembl
mRatBN7.2 Ensembl14103,351,386 - 103,351,706 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115959   ⟹   ENSRNOP00000094073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5135,974,034 - 135,977,708 (-)Ensembl
RefSeq Acc Id: NM_001030052   ⟹   NP_001025223
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85141,258,828 - 141,264,402 (-)NCBI
mRatBN7.25135,974,029 - 135,979,603 (-)NCBI
Dahl_SR_JrHsd5140,899,053 - 140,904,628 (-)NCBI
Lyon_Normotensive5142,876,653 - 142,882,228 (-)NCBI
Lyon_Hypertensive5142,063,882 - 142,069,457 (-)NCBI
F344_StmMcwi5135,620,668 - 135,626,239 (-)NCBI
Rnor_6.05141,390,577 - 141,405,453 (-)NCBI
Rnor_5.05145,178,499 - 145,196,014 (-)NCBI
RGSC_v3.45143,017,421 - 143,023,425 (-)RGD
Celera5134,511,122 - 134,516,696 (-)RGD
Sequence:
RefSeq Acc Id: XM_006238827   ⟹   XP_006238889
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85141,258,828 - 141,264,552 (-)NCBI
mRatBN7.25135,974,029 - 135,979,705 (-)NCBI
Rnor_6.05141,390,577 - 141,405,507 (-)NCBI
Rnor_5.05145,178,499 - 145,196,014 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006238828   ⟹   XP_006238890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85141,258,828 - 141,264,434 (-)NCBI
mRatBN7.25135,974,029 - 135,979,619 (-)NCBI
Rnor_6.05141,390,577 - 141,405,480 (-)NCBI
Rnor_5.05145,178,499 - 145,196,014 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001025223   ⟸   NM_001030052
- UniProtKB: B5DEL8 (UniProtKB/TrEMBL),   A0A0G2JZJ9 (UniProtKB/TrEMBL),   A0A9K3Y8A9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238889   ⟸   XM_006238827
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006238890   ⟸   XM_006238828
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000094073   ⟸   ENSRNOT00000115959
Ensembl Acc Id: ENSRNOP00000037699   ⟸   ENSRNOT00000036389
Ensembl Acc Id: ENSRNOP00000071076   ⟸   ENSRNOT00000083199
Ensembl Acc Id: ENSRNOP00000048968   ⟸   ENSRNOT00000042985

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DEL8-F1-model_v2 AlphaFold B5DEL8 1-106 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694005
Promoter ID:EPDNEW_R4530
Type:multiple initiation site
Name:Ndufs5_1
Description:NADH:ubiquinone oxidoreductase subunit S5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05141,405,469 - 141,405,529EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311081 AgrOrtholog
BioCyc Gene G2FUF-39998 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
Ensembl Genes ENSRNOG00000026646 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000029339 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000052764 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036389 ENTREZGENE
  ENSRNOT00000036389.7 UniProtKB/TrEMBL
  ENSRNOT00000042985.6 UniProtKB/TrEMBL
  ENSRNOT00000083199.3 UniProtKB/TrEMBL
InterPro NADH_UbQ_OxRdtase_FeS-su5 UniProtKB/TrEMBL
KEGG Report rno:362588 UniProtKB/TrEMBL
NCBI Gene 362588 ENTREZGENE
PANTHER NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 UniProtKB/TrEMBL
  PTHR15224 UniProtKB/TrEMBL
Pfam Ndufs5 UniProtKB/TrEMBL
PhenoGen Ndufs5 PhenoGen
PROSITE CHCH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000026646 RatGTEx
  ENSRNOG00000029339 RatGTEx
  ENSRNOG00000052764 RatGTEx
UniProt A0A0G2JZJ9 ENTREZGENE
  A0A9K3Y8A9 ENTREZGENE, UniProtKB/TrEMBL
  B5DEL8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A0G2JZJ9 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-12 Ndufs5  NADH:ubiquinone oxidoreductase subunit S5  Ndufs5  NADH dehydrogenase (ubiquinone) Fe-S protein 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Ndufs5  NADH dehydrogenase (ubiquinone) Fe-S protein 5  Ndufs5b  NADH dehydrogenase (ubiquinone) Fe-S protein 5b, 15kDa (NADH-coenzyme Q reductase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ndufs5b  NADH dehydrogenase (ubiquinone) Fe-S protein 5b, 15kDa (NADH-coenzyme Q reductase)  Ndufs5b_predicted  NADH dehydrogenase (ubiquinone) Fe-S protein 5b, 15kDa (NADH-coenzyme Q reductase) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ndufs5b_predicted  NADH dehydrogenase (ubiquinone) Fe-S protein 5b, 15kDa (NADH-coenzyme Q reductase) (predicted)      Symbol and Name status set to approved 70820 APPROVED