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Gene: Fam216a (family with sequence similarity 216, member A) Rattus norvegicus

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Symbol:

Fam216a

Name:

family with sequence similarity 216, member A

RGD ID:

1310861

Description:

Orthologous to human FAM216A (family with sequence similarity 216 member A); INTERACTS WITH amphetamine; bisphenol A; cadmium atom.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical protein LOC288667; LOC288667; MGC105520; RGD1310861; similar to RIKEN cDNA 1500011H22; uncharacterized protein C12orf24 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	39,859,307 - 39,868,450 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	39,859,172 - 39,868,442 (+)	Ensembl				GRCr8
mRatBN7.2	12	34,198,526 - 34,207,673 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	34,198,526 - 34,207,665 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	35,370,944 - 35,380,080 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	35,982,354 - 35,991,492 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	35,034,678 - 35,043,814 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	12	41,130,498 - 41,139,585 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	12	41,043,222 - 41,052,309 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	12	39,920,693 - 39,929,780 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	12	50,372,568 - 50,381,655 (+)	NCBI		F344_StmMcwi
Rnor_6.0	12	39,679,688 - 39,688,831 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	39,679,688 - 39,688,823 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	41,560,318 - 41,569,461 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	35,392,970 - 35,402,113 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	35,869,443 - 35,878,534 (+)	NCBI		Celera
RGSC_v3.1	12	35,256,357 - 35,265,497 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-palmitoylglycerol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrolein (ISO)

acrylamide (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (EXP)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

DDE (ISO)

dexamethasone (ISO)

dimethyl sulfoxide (ISO)

dorsomorphin (ISO)

ethyl methanesulfonate (ISO)

flutamide (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-ethyl-N-nitrosourea (ISO)

ozone (ISO)

paracetamol (EXP)

phenylmercury acetate (ISO)

quercitrin (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

T-2 toxin (ISO)

temozolomide (ISO)

testosterone (ISO)

thiram (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Fam216a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	39,859,307 - 39,868,450 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	39,859,172 - 39,868,442 (+)	Ensembl				GRCr8
mRatBN7.2	12	34,198,526 - 34,207,673 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	34,198,526 - 34,207,665 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	35,370,944 - 35,380,080 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	35,982,354 - 35,991,492 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	35,034,678 - 35,043,814 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	12	41,130,498 - 41,139,585 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	12	41,043,222 - 41,052,309 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	12	39,920,693 - 39,929,780 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	12	50,372,568 - 50,381,655 (+)	NCBI		F344_StmMcwi
Rnor_6.0	12	39,679,688 - 39,688,831 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	39,679,688 - 39,688,823 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	41,560,318 - 41,569,461 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	35,392,970 - 35,402,113 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	35,869,443 - 35,878,534 (+)	NCBI		Celera
RGSC_v3.1	12	35,256,357 - 35,265,497 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

FAM216A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	110,468,427 - 110,490,385 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	110,468,411 - 110,492,196 (+)	Ensembl			hg38	GRCh38
GRCh37	12	110,906,650 - 110,928,190 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	109,390,615 - 109,412,575 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	110,532,993 - 110,554,951 (+)	NCBI		Celera
Cytogenetic Map	12	q24.11	NCBI
HuRef	12	107,924,560 - 107,946,329 (+)	NCBI		HuRef
CHM1_1	12	110,874,062 - 110,896,004 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	110,446,166 - 110,468,079 (+)	NCBI		T2T-CHM13v2.0

Fam216a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	122,502,647 - 122,510,405 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	122,502,643 - 122,510,427 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	122,364,584 - 122,372,342 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	122,364,580 - 122,372,364 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	122,814,593 - 122,821,972 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	122,625,203 - 122,632,972 (-)	NCBI		MGSCv36	mm8
Celera	5	119,447,028 - 119,454,417 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	62.33	NCBI

Fam216a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	7,384,150 - 7,396,341 (+)	Ensembl
ChiLan1.0	NW_004955482	7,384,031 - 7,396,341 (+)	NCBI	ChiLan1.0	ChiLan1.0

FAM216A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	118,532,314 - 118,551,175 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	118,529,131 - 118,547,578 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	108,041,801 - 108,060,247 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	111,433,384 - 111,456,412 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	111,432,910 - 111,456,412 (+)	Ensembl			panPan2	panpan1.1

FAM216A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	8,291,710 - 8,300,639 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	8,291,705 - 8,300,646 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	8,455,338 - 8,464,264 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	8,549,392 - 8,558,278 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	8,549,385 - 8,558,285 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	8,508,629 - 8,517,511 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	8,567,423 - 8,576,306 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	8,522,896 - 8,531,778 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fam216a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	156,030,634 - 156,043,046 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936558	3,435,613 - 3,449,048 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936558	3,436,383 - 3,448,946 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FAM216A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	31,849,971 - 31,860,807 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	31,850,035 - 31,859,587 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	33,771,559 - 33,781,210 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FAM216A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	105,704,174 - 105,728,045 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	105,704,586 - 105,727,797 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	139,393,173 - 139,415,960 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fam216a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	21,408,982 - 21,420,387 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Fam216a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	31,475,075 - 31,484,479 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Fam216a
27 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	151
Count of miRNA genes:	125
Interacting mature miRNAs:	135
Transcripts:	ENSRNOT00000050398
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	29775522	42298555	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
1556747	Calcic1	Intracellular calcium level QTL 1		3.6	platelet calcium amount (VT:0010500)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
631829	Alc6	Alcohol consumption QTL 6	4.7		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	34243475	43352593	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat

Markers in Region

D5Mit118

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	34,205,981 - 34,206,142 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	39,687,144 - 39,687,300	NCBI	Rnor6.0
Rnor_5.0	12	41,567,774 - 41,567,930	UniSTS	Rnor5.0
RGSC_v3.4	12	35,400,426 - 35,400,582	UniSTS	RGSC3.4
Celera	12	35,876,899 - 35,877,003	UniSTS
Cytogenetic Map	12	q16	UniSTS

RH130330

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	34,207,441 - 34,207,608 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	39,688,600 - 39,688,766	NCBI	Rnor6.0
Rnor_5.0	12	41,569,230 - 41,569,396	UniSTS	Rnor5.0
RGSC_v3.4	12	35,401,882 - 35,402,048	UniSTS	RGSC3.4
Celera	12	35,878,303 - 35,878,469	UniSTS
RH 3.4 Map	12	606.9	UniSTS
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	90	59	6	354	190	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001008290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC104314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086384	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000050398 ⟹ ENSRNOP00000046271

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	39,859,172 - 39,868,442 (+)	Ensembl
mRatBN7.2 Ensembl	12	34,198,526 - 34,207,665 (+)	Ensembl
Rnor_6.0 Ensembl	12	39,679,688 - 39,688,823 (+)	Ensembl

RefSeq Acc Id:

NM_001008290 ⟹ NP_001008291

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	39,859,307 - 39,868,450 (+)	NCBI
mRatBN7.2	12	34,198,526 - 34,207,673 (+)	NCBI
Dahl_SR_JrHsd	12	41,130,498 - 41,139,585 (+)	NCBI
Lyon_Normotensive	12	41,043,222 - 41,052,309 (+)	NCBI
Lyon_Hypertensive	12	39,920,693 - 39,929,780 (+)	NCBI
F344_StmMcwi	12	50,372,568 - 50,381,655 (+)	NCBI
Rnor_6.0	12	39,679,688 - 39,688,831 (+)	NCBI
Rnor_5.0	12	41,560,318 - 41,569,461 (+)	NCBI
RGSC_v3.4	12	35,392,970 - 35,402,113 (+)	RGD
Celera	12	35,869,443 - 35,878,534 (+)	RGD

Sequence:

show sequence

TGCAGATCCTCCGAGGGTCTAGAATACTGAGGTGGAAGACACCTTTTGCTTTAGGGTGCGTGTG
TATGGATTTGCCCTGACGCGTCCTGGTCACGGAGAGATGTCAAGGCGCAGGAGTCTGGTTACCT
GAGGTCTCCTCCGCCTCGGGTCTAGTTTCAGGATCTCGGGTCGTCCTCCGCACCATCCGGGAGT
CGTTTGAGCAGGGTCAGAGGGTAGAGCCGGAGGCCGCAGGCTCACCGCGGACTGACGCACGCGT
GTGGACAGGATGCCGAGCCGTTGTCCCGGGGTCGCGGGGCCGCCCGCCTTGGCCCGGACGGAAG
GCAGCGAAGGGTCAGCTGGACAGTCTTATCACCAGAATTCCAAAGGCACTGGTGAGCAGCATAA
AGCAGAGAGAATCAAGGAGGGACACAGAATGTCCTCACACACTGCCAAACTGCAGGAGTTATGG
AGAACTACTCAAATCCAAACAATTCACATCCCTAAATCAATGACAGATGCGTCTTTTCTAAAGC
ATCCAGAACTCACCTCAGGCCAGAAGCGCTACCTGTGCAGCATTGCTAAGATCTGCAACTCCAG
CTATCTGAGGACCTTAATGAAGAGGCAGTACATGCATCTGTTTCATCACGGGTTACAGAAGCCA
GGTGTCCTCACTCATCATAGAAGCCATATCAGCTCTCGATACTCACAGAAACAGCATTCCCCCT
GCACTACATGGAGACACCATCTGGAGAGAGAAGACTCTCTGGGCATTGCAGCAGAAGCACCTGA
AATGATCATACATGCCCTTTGGAGACCCCTGAGACACAAAGAAGGGTTAAAAATTGGATATGCA
TCTAAAACAAGATGCAAGTCCCTGAAGATTTTTAGAAGACCAGGCAGACTGTTCTTGCTACCAG
TTTCTTCTAAGGATTATCAGCCATGCATGAACGATGAGACAAAGGAAGAGGATCTACTGAATGA
GTGCATGCAGTCCATGTCCATTCAGGAACAAGGCTCATCTCATGCCAGCCTGACAGTCTCGTGT
CCCACACCAAGTTCAGCCATCCCCTAATACCCACATGTTGAGCCTGAGGGGACAGTGAAGAGTT
GGAACCATGTATGGGATAGTGCTAGTAGCTGCTGGTATGTTATTTTAGTTATTGAGAAATTTAT
AATAGCCTTCTTCGTCTAATATATTTCCGTGTTATATCTGTAATGTATGCTTGTTTCTAGCTAG
AACAATTAAAATTTTACTTGCCAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001008291	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86384	(Get FASTA)	NCBI Sequence Viewer
	EDM13691	(Get FASTA)	NCBI Sequence Viewer
	EDM13692	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000046271
	ENSRNOP00000046271.2
GenBank Protein	Q5U1Y9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001008291 ⟸ NM_001008290

- UniProtKB:

Q5U1Y9 (UniProtKB/Swiss-Prot), A6J1A2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPSRCPGVAGPPALARTEGSEGSAGQSYHQNSKGTGEQHKAERIKEGHRMSSHTAKLQELWRTT
QIQTIHIPKSMTDASFLKHPELTSGQKRYLCSIAKICNSSYLRTLMKRQYMHLFHHGLQKPGVL
THHRSHISSRYSQKQHSPCTTWRHHLEREDSLGIAAEAPEMIIHALWRPLRHKEGLKIGYASKT
RCKSLKIFRRPGRLFLLPVSSKDYQPCMNDETKEEDLLNECMQSMSIQEQGSSHASLTVSCPTP
SSAIP

hide sequence

Ensembl Acc Id:

ENSRNOP00000046271 ⟸ ENSRNOT00000050398

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5U1Y9-F1-model_v2	AlphaFold	Q5U1Y9	1-261	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698646

Promoter ID:

EPDNEW_R9171

Type:

initiation region

Name:

Fam216a_1

Description:

family with sequence similarity 216, member A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	39,679,645 - 39,679,705	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310861	AgrOrtholog
BioCyc Gene	G2FUF-19245	BioCyc
Ensembl Genes	ENSRNOG00000031731	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000050398	ENTREZGENE
	ENSRNOT00000050398.3	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7301624	IMAGE-MGC_LOAD
InterPro	FAM216	UniProtKB/Swiss-Prot
KEGG Report	rno:288667	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105520	IMAGE-MGC_LOAD
NCBI Gene	288667	ENTREZGENE
PANTHER	PROTEIN FAM216A	UniProtKB/Swiss-Prot
	PTHR16476	UniProtKB/Swiss-Prot
Pfam	FAM216B	UniProtKB/Swiss-Prot
PhenoGen	Fam216a	PhenoGen
RatGTEx	ENSRNOG00000031731	RatGTEx
UniProt	A6J1A2	ENTREZGENE, UniProtKB/TrEMBL
	F216A_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-10	Fam216a	family with sequence similarity 216, member A	RGD1310861	similar to RIKEN cDNA 1500011H22	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1310861	similar to RIKEN cDNA 1500011H22	RGD1310861_predicted	similar to RIKEN cDNA 1500011H22 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1310861_predicted	similar to RIKEN cDNA 1500011H22 (predicted)	LOC288667_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC288667_predicted	similar to RIKEN cDNA 1500011H22 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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