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Gene: Pus3 (pseudouridine synthase 3) Rattus norvegicus

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Symbol:

Pus3

Name:

pseudouridine synthase 3

RGD ID:

1310757

Description:

Predicted to enable tRNA pseudouridine(38/39) synthase activity. Predicted to be involved in mRNA pseudouridine synthesis and tRNA pseudouridine synthesis. Predicted to be active in cytoplasm and nucleus. Orthologous to human PUS3 (pseudouridine synthase 3); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC315554; pseudouridylate synthase 3; RGD1310757; similar to CG3045-PA; tRNA pseudouridine synthase 3; tRNA pseudouridine(38/39) synthase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PUS3 (pseudouridine synthase 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Pus3 (pseudouridine synthase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pus3 (pseudouridine synthase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PUS3 (pseudouridine synthase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PUS3 (pseudouridine synthase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pus3 (pseudouridine synthase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PUS3 (pseudouridine synthase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PUS3 (pseudouridine synthase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pus3 (pseudouridine synthase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pus3 (pseudouridine synthase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	IGFLR1 (IGF like family receptor 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PUS3 (pseudouridine synthase 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pus3 (pseudouridine synthase 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pus3 (pseudouridylate synthase 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3045	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DEG1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DEG1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tag-124	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pus3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	pus3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	42,168,194 - 42,176,527 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	42,168,251 - 42,176,522 (+)	Ensembl				GRCr8
mRatBN7.2	8	33,910,461 - 33,918,716 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	33,911,357 - 33,918,714 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	37,993,109 - 37,995,299 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	36,276,158 - 36,278,348 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	34,138,988 - 34,141,178 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	36,760,874 - 36,769,167 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	36,766,977 - 36,769,162 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	36,778,299 - 36,785,655 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	35,349,230 - 35,351,420 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	35,337,614 - 35,339,804 (+)	NCBI		Celera
RGSC_v3.1	8	35,358,024 - 35,363,141 (+)	NCBI
Cytogenetic Map	8	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neurodevelopmental Disorder with Microcephaly and Gray Sclerae (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(S)-colchicine (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

acrolein (ISO)

acrylamide (ISO)

adenine (ISO)

alpha-pinene (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

Enterolactone (ISO)

ethyl methanesulfonate (ISO)

etoposide (ISO)

fenvalerate (EXP)

folic acid (ISO)

gallic acid (ISO)

hydrogen peroxide (ISO)

hydroxyurea (ISO)

L-methionine (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

mitomycin C (ISO)

ozone (ISO)

paracetamol (ISO)

pirinixic acid (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

succimer (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

pseudouridine synthesis (IEA)

RNA modification (IEA)

tRNA processing (IEA)

tRNA pseudouridine synthesis (IEA,ISO)

Cellular Component

nucleus (IEA)

Molecular Function

isomerase activity (IEA)

pseudouridine synthase activity (IEA,ISO)

RNA binding (IEA)

tRNA pseudouridine(38/39) synthase activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11027153	PMID:12477932	PMID:27055666

Genomics

Comparative Map Data

Pus3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	42,168,194 - 42,176,527 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	42,168,251 - 42,176,522 (+)	Ensembl				GRCr8
mRatBN7.2	8	33,910,461 - 33,918,716 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	33,911,357 - 33,918,714 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	37,993,109 - 37,995,299 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	36,276,158 - 36,278,348 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	34,138,988 - 34,141,178 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	36,760,874 - 36,769,167 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	36,766,977 - 36,769,162 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	36,778,299 - 36,785,655 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	35,349,230 - 35,351,420 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	35,337,614 - 35,339,804 (+)	NCBI		Celera
RGSC_v3.1	8	35,358,024 - 35,363,141 (+)	NCBI
Cytogenetic Map	8	q21	NCBI

PUS3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	125,893,485 - 125,903,206 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	125,893,485 - 125,903,224 (-)	Ensembl			hg38	GRCh38
GRCh37	11	125,763,380 - 125,773,101 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	125,268,590 - 125,278,315 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	11	125,268,590 - 125,278,315	NCBI
Celera	11	122,923,405 - 122,933,137 (-)	NCBI		Celera
Cytogenetic Map	11	q24.2	NCBI
HuRef	11	121,705,358 - 121,715,092 (-)	NCBI		HuRef
CHM1_1	11	125,650,152 - 125,659,884 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	125,922,358 - 125,932,075 (-)	NCBI		T2T-CHM13v2.0

Pus3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	35,469,856 - 35,478,697 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	35,469,891 - 35,478,697 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	35,558,560 - 35,567,401 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	35,558,595 - 35,567,401 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	35,367,051 - 35,374,985 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	35,309,137 - 35,316,854 (+)	NCBI		MGSCv36	mm8
Celera	9	32,796,829 - 32,804,763 (+)	NCBI		Celera
Cytogenetic Map	9	A4	NCBI
cM Map	9	20.32	NCBI

Pus3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	26,942,082 - 26,945,624 (-)	Ensembl
ChiLan1.0	NW_004955412	26,941,837 - 26,951,524 (-)	NCBI	ChiLan1.0	ChiLan1.0

PUS3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	126,578,206 - 126,623,487 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	127,685,945 - 127,731,051 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	120,709,264 - 120,718,773 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	124,622,279 - 124,631,736 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	124,622,279 - 124,629,508 (-)	Ensembl			panPan2	panpan1.1

PUS3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	8,586,374 - 8,597,108 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	8,586,324 - 8,596,881 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	8,647,666 - 8,658,403 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	8,543,726 - 8,554,694 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	8,544,880 - 8,554,480 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	8,611,659 - 8,622,390 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	8,585,895 - 8,596,627 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	8,619,943 - 8,630,897 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pus3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	108,114,967 - 108,127,688 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936572	6,322,727 - 6,335,599 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936572	6,322,725 - 6,331,844 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PUS3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	53,018,883 - 53,028,560 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	53,018,878 - 53,028,605 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	58,625,406 - 58,635,134 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PUS3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	117,024,697 - 117,035,102 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	117,025,009 - 117,027,510 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666043	9,036,634 - 9,046,841 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pus3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624812	41,652 - 52,973 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624812	41,234 - 52,962 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pus3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	31,097,411 - 31,105,620 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pus3
59 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	59
Count of miRNA genes:	52
Interacting mature miRNAs:	56
Transcripts:	ENSRNOT00000017648
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39752803	84752803	Rat
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	17994105	50763951	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	39106258	91341052	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	16994642	61994642	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	39106258	91341052	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	39106363	103375781	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	15952279	60952279	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	12964165	57964165	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	39106258	84106258	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	12964165	57964165	Rat
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	10382540	55382540	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	39106363	103375781	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	16994642	61994642	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	10382540	55382540	Rat
61337	Bp22	Blood pressure QTL 22	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	51589833	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	39106258	103375958	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	12964165	57964165	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	10382540	55382540	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	39106258	91341052	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
2302278	Gluco36	Glucose level QTL 36	4.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	37760859	58991895	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	10382540	55382540	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	37760859	61459705	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	35464071	71842899	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	39106258	84106258	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	31543661	76543661	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	84106258	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	17993862	62252873	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	67378345	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	39106258	91341052	Rat
724540	Uae8	Urinary albumin excretion QTL 8	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	8	39106258	103375958	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
1359021	Bp271	Blood pressure QTL 271	1.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	34125902	55607752	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	17994105	50763951	Rat
70206	Alc20	Alcohol consumption QTL 20	2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	8	39106258	49610361	Rat

Markers in Region

BF389095

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	33,916,607 - 33,916,740 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	36,767,061 - 36,767,193	NCBI	Rnor6.0
Rnor_5.0	8	36,783,547 - 36,783,679	UniSTS	Rnor5.0
RGSC_v3.4	8	35,349,314 - 35,349,446	UniSTS	RGSC3.4
Celera	8	35,337,698 - 35,337,830	UniSTS
RH 3.4 Map	8	301.3	UniSTS
Cytogenetic Map	8	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595618	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595620	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265423	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC132671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC127541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC158693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000017648 ⟹ ENSRNOP00000017648

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	42,168,251 - 42,176,522 (+)	Ensembl
mRatBN7.2 Ensembl	8	33,911,357 - 33,918,714 (+)	Ensembl
Rnor_6.0 Ensembl	8	36,766,977 - 36,769,162 (+)	Ensembl

RefSeq Acc Id:

NM_001108134 ⟹ NP_001101604

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	42,174,337 - 42,176,527 (+)	NCBI
mRatBN7.2	8	33,916,524 - 33,918,714 (+)	NCBI
Rnor_6.0	8	36,766,977 - 36,769,167 (+)	NCBI
Rnor_5.0	8	36,778,299 - 36,785,655 (+)	NCBI
RGSC_v3.4	8	35,349,230 - 35,351,420 (+)	RGD
Celera	8	35,337,614 - 35,339,804 (+)	RGD

Sequence:

show sequence

GACCTGCATGATTTCTTCCTGGGGATGCCATGGCTGAAACCACAGACAGAAATCAGATTGAGAA
ACTTCTAAGCAGAGTAAAGGAACTGGAGCAGGAAGTGGAAAGACTTAAGAAAGAACAAGCCAAC
AATATAAAAGACACAAGTGTCAGAGAAAATTCTTTAGGCTGTGGAAAAGCTAAGCGTGCTTTTG
ATTTTAGTGCTCATGGCCGTAGACATGTAGCTCTAAAAATAGCCTATCTAGGCTGGGGATACCA
GGGCTTTGCCAGTCAGGAAAACACAAGCAATACCATTGAAGAGAAACTGTTTGAGGCTTTAATA
AAGACCCGACTAGTAGAAAGCAGACAGACTTCCAACTATCACCGGTGTGGTCGAACAGACAAAG
GAGTTAGCGCCTTTGGACAGGTAATTTCTCTGGACCTGCGTTCTCAGTTTCCAAGGAGCAGGGA
TTCAGAAGATTCTAATTTAAAAGATGGAGCTGATGATATTGCTAAAGAGATCCGTTATGCTCAC
ATTCTCAATCGGGTGCTTCCTGCAGACATCAGGGTATTGGCCTGGGCCCCTGCAGAACCTAGCT
TCAGTGCTAGGTTTAGCTGTCTTGAGCGGACCTACCGCTACTTTTTCCCCTGTGCTGATTTAGA
TATTGCAACTATGAATTATGCAGCTCAGAAATACGTTGGCACTCATGATTTCAGAAACTTGTGT
AAGATGGACGTGGCCAATGGCGTGACTAATTTTCAGAGGACTATCCTGTCTGCACAAGTGCAAA
CAGTGGCCCAGAGCCCAGGTGAGGAGGGAAGGCAAGGGCCATTCCAGTTATGTCAATTTGAAGT
GATTGGCCAGGCATTCCTGTATCATCAAGTTCGGTGTATGATGGCTATCCTCTTCCTGATTGGC
CAAGGAATGGAGAAGCCAGAGATTATTGATGAACTGCTGAACATAGAGAAAAATCCCCAGAAAC
CGCAATATAGCATGGCTGTTGAATTTCCTCTAGTCTTATATGACTGTAAATTTGAAAATACCAA
GTGGATTTATGATCACGAGGTTCACGAATTCAATGTTACTCACCTACAACAGCTATGGGCTAAT
CATGCTGTTAAAACTCACATGCTATATAGTATGCTACAAGGACTAGACTCTGTTATGGTAACAT
GCGCAGCAGGAACAAAGACTGGTGAAGCAACAGAATGGAGAAACATTCGACCCTCTGTCATAAA
GCACACTAGTGCCTTTGTAGAAGGAGTGAGAATGCGCACATATAAGCCCCTCATGGCTCGCCCC
AAATGCCAAGGACTGGAATCCCGGATCCAGCATTTTGTACGAAGAGGACGAATTGAGCACCCAC
ATTTACTCCATAAGGAAGAAAAAAAAGCAAAGAGGGACTGTGCTGACAAAGAAGAAAATATTGT
TTTAGAGAATCCAACGAAGAGGGTTTGTATAATAGATGCAGAAATTAACAGCATTGTATAATTC
CAGGAAGCTAGCATCTCTAGCAGGATCCAGGGAGCAACAACGAATTAAAATTTTAATGACTAGC
AAAAGACCTAACAAGTTCTTAAATATTAAGGGTGTATTCTTTAATCCCTGTCCAAAAATATTAG
GAAATGAAAGACGCAAAGACCACTTGTCAGTTATATGCACCTGGAAATCTGTGTTTTTCGTTCA
AATCCATTAAAGCCTGGTCTACAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017595618 ⟹ XP_017451107

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	42,168,194 - 42,176,527 (+)	NCBI
mRatBN7.2	8	33,910,506 - 33,918,716 (+)	NCBI
Rnor_6.0	8	36,760,919 - 36,769,167 (+)	NCBI

Sequence:

show sequence

GTCGGCCATCCGCACAGCAGAGAGAAAGAAAGTGGGCACGGAGGCGGTAGACACACCGCGCTGC
AGGTTCTCTCTCATGCCGCTATTTCTCCTGACAGCCCTGCTTGGGCATCACAACGTGTGAGATT
GCACCGTGGAGGGGCAGATGGCCTTGAGCAGAGAGAGGTTCGGAAAGAAAACAGAATTCAAGTG
CGGACATCTGTTTCAGTCCTGGATACCGGGGATATGCCCACATACACGCGTATTTTAATTTTTG
TTGTGAGACCAGATTATAATTTCGCCATTTGTTCCTTATTGATTTTGTCTTGCGGTGAAGAGGA
AGCTGCATCAGAACCCTGCGCATTCCGTGGGTTTCGGCTTAAAGCCCACACCCGGCCTTCGGAA
CTACATTTCCCAGAACCGCAGGCGCACTTTTAGTGAGGCTGCGCATGCTTACTGGAGGCGAAAA
GTAACAGCTTCCGGCTAGTCGCGTGGCCGCGCACTGAGGATCGGGAGGGTGGACCTGCATGATT
TCTTCCTGGGGATGCCATGGCTGAAACCACAGACAGAAATCAGATTGAGAAACTTCTAAGCAGA
GTAAAGGAACTGGAGCAGGAAGTGGAAAGACTTAAGAAAGAACAAGCCAACAATATAAAAGACA
CAAGTGTCAGAGAAAATTCTTTAGGCTGTGGAAAAGCTAAGCGTGCTTTTGATTTTAGTGCTCA
TGGCCGTAGACATGTAGCTCTAAAAATAGCCTATCTAGGCTGGGGATACCAGGGCTTTGCCAGT
CAGGAAAACACAAGCAATACCATTGAAGAGAAACTGTTTGAGGCTTTAATAAAGACCCGACTAG
TAGAAAGCAGACAGACTTCCAACTATCACCGGTGTGGTCGAACAGACAAAGGAGTTAGCGCCTT
TGGACAGGTAATTTCTCTGGACCTGCGTTCTCAGTTTCCAAGGAGCAGGGATTCAGAAGATTCT
AATTTAAAAGATGGAGCTGATGATATTGCTAAAGAGATCCGTTATGCTCACATTCTCAATCGGG
TGCTTCCTGCAGACATCAGGGTATTGGCCTGGGCCCCTGCAGAACCTAGCTTCAGTGCTAGGTT
TAGCTGTCTTGAGCGGACCTACCGCTACTTTTTCCCCTGTGCTGATTTAGATATTGCAACTATG
AATTATGCAGCTCAGAAATACGTTGGCACTCATGATTTCAGAAACTTGTGTAAGATGGACGTGG
CCAATGGCGTGACTAATTTTCAGAGGACTATCCTGTCTGCACAAGTGCAAACAGTGGCCCAGAG
CCCAGGTGAGGAGGGAAGGCAAGGGCCATTCCAGTTATGTCAATTTGAAGTGATTGGCCAGGCA
TTCCTGTATCATCAAGTTCGGTGTATGATGGCTATCCTCTTCCTGATTGGCCAAGGAATGGAGA
AGCCAGAGATTATTGATGAACTGCTGAACATAGAGAAAAATCCCCAGAAACCGCAATATAGCAT
GGCTGTTGAATTTCCTCTAGTCTTATATGACTGTAAATTTGAAAATACCAAGTGGATTTATGAT
CACGAGGTTCACGAATTCAATGTTACTCACCTACAACAGCTATGGGCTAATCATGCTGTTAAAA
CTCACATGCTATATAGTATGCTACAAGGACTAGACTCTGTTATGGTAACATGCGCAGCAGGAAC
AAAGACTGGTGAAGCAACAGAATGGAGAAACATTCGACCCTCTGTCATAAAGCACACTAGTGCC
TTTGTAGAAGGAGTGAGAATGCGCACATATAAGCCCCTCATGGCTCGCCCCAAATGCCAAGGAC
TGGAATCCCGGATCCAGCATTTTGTACGAAGAGGACGAATTGAGCACCCACATTTACTCCATAA
GGAAGAAAAAAAAGCAAAGAGGGACTGTGCTGACAAAGAAGAAAATATTGTTTTAGAGAATCCA
ACGAAGAGGGTTTGTATAATAGATGCAGAAATTAACAGCATTGTATAATTCCAGGAAGCTAGCA
TCTCTAGCAGGATCCAGGGAGCAACAACGAATTAAAATTTTAATGACTAGCAAAAGACCTAACA
AGTTCTTAAATATTAAGGGTGTATTCTTTAATCCCTGTCCAAAAATATTAGGAAATGAAAGACG
CAAAGACCACTTGTCAGTTATATGCACCTGGAAATCTGTGTTTTTCGTTCAAATCCATTAAAGC
CTGGTCTACAAATA

hide sequence

RefSeq Acc Id:

XM_017595619 ⟹ XP_017451108

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	42,168,240 - 42,176,527 (+)	NCBI
mRatBN7.2	8	33,910,461 - 33,918,716 (+)	NCBI
Rnor_6.0	8	36,760,919 - 36,769,167 (+)	NCBI

Sequence:

show sequence

GTCGGCCATCCGCACAGCAGAGAGAAAGAAAGTGGGCACGGAGGCGGTAGACACACCGCGCTGC
AGGTTCTCTCTCATGCCGCTATTTCTCCTGACAGCCCTGCTTGGGCATCACAACGTGTGAGATT
GCACCGTGGAGGGGCAGATGGCCTTGAGCAGAGAGAGACCAGATTATAATTTCGCCATTTGTTC
CTTATTGATTTTGTCTTGCGGTGAAGAGGAAGCTGCATCAGAACCCTGCGCATTCCGTGGGTTT
CGGCTTAAAGCCCACACCCGGCCTTCGGAACTACATTTCCCAGAACCGCAGGCGCACTTTTAGT
GAGGCTGCGCATGCTTACTGGAGGCGAAAAGTAACAGCTTCCGGCTAGTCGCGTGGCCGCGCAC
TGAGGATCGGGAGGGTGGACCTGCATGATTTCTTCCTGGGGATGCCATGGCTGAAACCACAGAC
AGAAATCAGATTGAGAAACTTCTAAGCAGAGTAAAGGAACTGGAGCAGGAAGTGGAAAGACTTA
AGAAAGAACAAGCCAACAATATAAAAGACACAAGTGTCAGAGAAAATTCTTTAGGCTGTGGAAA
AGCTAAGCGTGCTTTTGATTTTAGTGCTCATGGCCGTAGACATGTAGCTCTAAAAATAGCCTAT
CTAGGCTGGGGATACCAGGGCTTTGCCAGTCAGGAAAACACAAGCAATACCATTGAAGAGAAAC
TGTTTGAGGCTTTAATAAAGACCCGACTAGTAGAAAGCAGACAGACTTCCAACTATCACCGGTG
TGGTCGAACAGACAAAGGAGTTAGCGCCTTTGGACAGGTAATTTCTCTGGACCTGCGTTCTCAG
TTTCCAAGGAGCAGGGATTCAGAAGATTCTAATTTAAAAGATGGAGCTGATGATATTGCTAAAG
AGATCCGTTATGCTCACATTCTCAATCGGGTGCTTCCTGCAGACATCAGGGTATTGGCCTGGGC
CCCTGCAGAACCTAGCTTCAGTGCTAGGTTTAGCTGTCTTGAGCGGACCTACCGCTACTTTTTC
CCCTGTGCTGATTTAGATATTGCAACTATGAATTATGCAGCTCAGAAATACGTTGGCACTCATG
ATTTCAGAAACTTGTGTAAGATGGACGTGGCCAATGGCGTGACTAATTTTCAGAGGACTATCCT
GTCTGCACAAGTGCAAACAGTGGCCCAGAGCCCAGGTGAGGAGGGAAGGCAAGGGCCATTCCAG
TTATGTCAATTTGAAGTGATTGGCCAGGCATTCCTGTATCATCAAGTTCGGTGTATGATGGCTA
TCCTCTTCCTGATTGGCCAAGGAATGGAGAAGCCAGAGATTATTGATGAACTGCTGAACATAGA
GAAAAATCCCCAGAAACCGCAATATAGCATGGCTGTTGAATTTCCTCTAGTCTTATATGACTGT
AAATTTGAAAATACCAAGTGGATTTATGATCACGAGGTTCACGAATTCAATGTTACTCACCTAC
AACAGCTATGGGCTAATCATGCTGTTAAAACTCACATGCTATATAGTATGCTACAAGGACTAGA
CTCTGTTATGGTAACATGCGCAGCAGGAACAAAGACTGGTGAAGCAACAGAATGGAGAAACATT
CGACCCTCTGTCATAAAGCACACTAGTGCCTTTGTAGAAGGAGTGAGAATGCGCACATATAAGC
CCCTCATGGCTCGCCCCAAATGCCAAGGACTGGAATCCCGGATCCAGCATTTTGTACGAAGAGG
ACGAATTGAGCACCCACATTTACTCCATAAGGAAGAAAAAAAAGCAAAGAGGGACTGTGCTGAC
AAAGAAGAAAATATTGTTTTAGAGAATCCAACGAAGAGGGTTTGTATAATAGATGCAGAAATTA
ACAGCATTGTATAATTCCAGGAAGCTAGCATCTCTAGCAGGATCCAGGGAGCAACAACGAATTA
AAATTTTAATGACTAGCAAAAGACCTAACAAGTTCTTAAATATTAAGGGTGTATTCTTTAATCC
CTGTCCAAAAATATTAGGAAATGAAAGACGCAAAGACCACTTGTCAGTTATATGCACCTGGAAA
TCTGTGTTTTTCGTTCAAATCCATTAAAGCCTGGTCTACAAATA

hide sequence

RefSeq Acc Id:

XM_063265423 ⟹ XP_063121493

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	42,168,772 - 42,176,527 (+)	NCBI

RefSeq Acc Id:

XM_063265424 ⟹ XP_063121494

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	42,168,213 - 42,176,527 (+)	NCBI

RefSeq Acc Id:

XM_063265425 ⟹ XP_063121495

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	42,171,768 - 42,176,527 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101604	(Get FASTA)	NCBI Sequence Viewer
	XP_017451107	(Get FASTA)	NCBI Sequence Viewer
	XP_017451108	(Get FASTA)	NCBI Sequence Viewer
	XP_063121493	(Get FASTA)	NCBI Sequence Viewer
	XP_063121494	(Get FASTA)	NCBI Sequence Viewer
	XP_063121495	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI58694	(Get FASTA)	NCBI Sequence Viewer
	EDL83266	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017648
	ENSRNOP00000017648.4

RefSeq Acc Id:

NP_001101604 ⟸ NM_001108134

- UniProtKB:

B0BN58 (UniProtKB/TrEMBL), A6JYL0 (UniProtKB/TrEMBL), F6RES9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAETTDRNQIEKLLSRVKELEQEVERLKKEQANNIKDTSVRENSLGCGKAKRAFDFSAHGRRHV
ALKIAYLGWGYQGFASQENTSNTIEEKLFEALIKTRLVESRQTSNYHRCGRTDKGVSAFGQVIS
LDLRSQFPRSRDSEDSNLKDGADDIAKEIRYAHILNRVLPADIRVLAWAPAEPSFSARFSCLER
TYRYFFPCADLDIATMNYAAQKYVGTHDFRNLCKMDVANGVTNFQRTILSAQVQTVAQSPGEEG
RQGPFQLCQFEVIGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFP
LVLYDCKFENTKWIYDHEVHEFNVTHLQQLWANHAVKTHMLYSMLQGLDSVMVTCAAGTKTGEA
TEWRNIRPSVIKHTSAFVEGVRMRTYKPLMARPKCQGLESRIQHFVRRGRIEHPHLLHKEEKKA
KRDCADKEENIVLENPTKRVCIIDAEINSIV

hide sequence

RefSeq Acc Id:	XP_017451107 ⟸ XM_017595618
- Peptide Label:	isoform X1
- UniProtKB:	B0BN58 (UniProtKB/TrEMBL), A6JYL0 (UniProtKB/TrEMBL), F6RES9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAETTDRNQIEKLLSRVKELEQEVERLKKEQANNIKDTSVRENSLGCGKAKRAFDFSAHGRRHV ALKIAYLGWGYQGFASQENTSNTIEEKLFEALIKTRLVESRQTSNYHRCGRTDKGVSAFGQVIS LDLRSQFPRSRDSEDSNLKDGADDIAKEIRYAHILNRVLPADIRVLAWAPAEPSFSARFSCLER TYRYFFPCADLDIATMNYAAQKYVGTHDFRNLCKMDVANGVTNFQRTILSAQVQTVAQSPGEEG RQGPFQLCQFEVIGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFP LVLYDCKFENTKWIYDHEVHEFNVTHLQQLWANHAVKTHMLYSMLQGLDSVMVTCAAGTKTGEA TEWRNIRPSVIKHTSAFVEGVRMRTYKPLMARPKCQGLESRIQHFVRRGRIEHPHLLHKEEKKA KRDCADKEENIVLENPTKRVCIIDAEINSIV hide sequence

RefSeq Acc Id:	XP_017451108 ⟸ XM_017595619
- Peptide Label:	isoform X1
- UniProtKB:	B0BN58 (UniProtKB/TrEMBL), A6JYL0 (UniProtKB/TrEMBL), F6RES9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAETTDRNQIEKLLSRVKELEQEVERLKKEQANNIKDTSVRENSLGCGKAKRAFDFSAHGRRHV ALKIAYLGWGYQGFASQENTSNTIEEKLFEALIKTRLVESRQTSNYHRCGRTDKGVSAFGQVIS LDLRSQFPRSRDSEDSNLKDGADDIAKEIRYAHILNRVLPADIRVLAWAPAEPSFSARFSCLER TYRYFFPCADLDIATMNYAAQKYVGTHDFRNLCKMDVANGVTNFQRTILSAQVQTVAQSPGEEG RQGPFQLCQFEVIGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFP LVLYDCKFENTKWIYDHEVHEFNVTHLQQLWANHAVKTHMLYSMLQGLDSVMVTCAAGTKTGEA TEWRNIRPSVIKHTSAFVEGVRMRTYKPLMARPKCQGLESRIQHFVRRGRIEHPHLLHKEEKKA KRDCADKEENIVLENPTKRVCIIDAEINSIV hide sequence

Ensembl Acc Id:

ENSRNOP00000017648 ⟸ ENSRNOT00000017648

RefSeq Acc Id:	XP_063121494 ⟸ XM_063265424
- Peptide Label:	isoform X1
- UniProtKB:	A6JYL0 (UniProtKB/TrEMBL), B0BN58 (UniProtKB/TrEMBL), F6RES9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121493 ⟸ XM_063265423
- Peptide Label:	isoform X1
- UniProtKB:	A6JYL0 (UniProtKB/TrEMBL), B0BN58 (UniProtKB/TrEMBL), F6RES9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121495 ⟸ XM_063265425
- Peptide Label:	isoform X1
- UniProtKB:	A6JYL0 (UniProtKB/TrEMBL), B0BN58 (UniProtKB/TrEMBL), F6RES9 (UniProtKB/TrEMBL)

Protein Domains

Pseudouridine synthase I TruA alpha/beta

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B0BN58-F1-model_v2	AlphaFold	B0BN58	1-479	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310757	AgrOrtholog
BioCyc Gene	G2FUF-31166	BioCyc
Ensembl Genes	ENSRNOG00000012994	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000017648	ENTREZGENE
	ENSRNOT00000017648.8	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.580	UniProtKB/TrEMBL
	3.30.70.660	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9023160	IMAGE-MGC_LOAD
InterPro	PsdUridine_synth_cat_dom	UniProtKB/TrEMBL
	PsdUridine_synth_TruA	UniProtKB/TrEMBL
	PsdUridine_synth_TruA_a/b_dom	UniProtKB/TrEMBL
	PsdUridine_synth_TruA_C	UniProtKB/TrEMBL
	Pus3-like	UniProtKB/TrEMBL
	TruA/RsuA/RluB/E/F_N	UniProtKB/TrEMBL
KEGG Report	rno:315554	UniProtKB/TrEMBL
MGC_CLONE	MGC:187724	IMAGE-MGC_LOAD
NCBI Gene	315554	ENTREZGENE
PANTHER	PseudoU_synth_1	UniProtKB/TrEMBL
	TRNA PSEUDOURIDINE(38/39) SYNTHASE	UniProtKB/TrEMBL
Pfam	PseudoU_synth_1	UniProtKB/TrEMBL
PhenoGen	Pus3	PhenoGen
RatGTEx	ENSRNOG00000012994	RatGTEx
Superfamily-SCOP	PsdUridine_synth_cat_dom	UniProtKB/TrEMBL
UniProt	A6JYL0	ENTREZGENE, UniProtKB/TrEMBL
	B0BN58	ENTREZGENE
	F6RES9	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	B0BN58	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-09-21	Pus3	pseudouridine synthase 3	Pus3	pseudouridylate synthase 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-17	Pus3	pseudouridylate synthase 3	Pus3	pseudouridine synthase 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-04	Pus3	pseudouridine synthase 3	Pus3_predicted	pseudouridylate synthase 3 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Pus3_predicted	pseudouridylate synthase 3 (predicted)	RGD1310757_predicted	similar to CG3045-PA (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1310757_predicted	similar to CG3045-PA (predicted)	LOC315554_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC315554_predicted	similar to CG3045-PA (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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