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Gene: Fndc1 (fibronectin type III domain containing 1) Rattus norvegicus

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Symbol:

Fndc1

Name:

fibronectin type III domain containing 1

RGD ID:

1310640

Description:

Acts upstream of or within several processes, including cellular response to hypoxia; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of protein phosphorylation. Located in cell-cell junction; mitochondrial membrane; and plasma membrane. Orthologous to human FNDC1 (fibronectin type III domain containing 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

activator of G-protein signaling 8; fibronectin type III domain-containing protein 1; LOC308099

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	49,686,856 - 49,769,263 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	49,686,856 - 49,769,263 (+)	Ensembl				GRCr8
mRatBN7.2	1	47,281,839 - 47,364,247 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	47,281,844 - 47,364,259 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	47,851,601 - 47,912,467 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	53,832,549 - 53,893,699 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	47,927,067 - 47,987,956 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	1	49,310,487 - 49,393,412 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	1	48,649,857 - 48,732,787 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	1	49,811,147 - 49,894,092 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	1	48,090,897 - 48,173,298 (+)	NCBI		F344_StmMcwi
Rnor_6.0	1	47,605,211 - 47,687,499 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	47,605,262 - 47,687,504 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	48,905,631 - 48,987,877 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	41,522,019 - 41,583,357 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	42,986,709 - 43,047,709 (+)	NCBI		Celera
RGSC_v3.1	1	41,524,963 - 41,632,204 (+)	NCBI
Cytogenetic Map	1	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,4'-trichlorobiphenyl (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

beta-naphthoflavone (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bromobenzene (EXP)

butanal (ISO)

cantharidin (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chrysene (ISO)

cisplatin (ISO)

cocaine (ISO)

copper atom (EXP)

copper(0) (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dioxygen (EXP,ISO)

diquat (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

fulvestrant (ISO)

furan (EXP)

gentamycin (EXP)

lead(0) (ISO)

lipopolysaccharide (ISO)

methapyrilene (ISO)

microcystin-LR (EXP)

mono(2-ethylhexyl) phthalate (ISO)

Monobutylphthalate (ISO)

N-nitrosodiethylamine (EXP)

ozone (ISO)

paracetamol (EXP)

paraquat (EXP)

PCB138 (ISO)

phenylmercury acetate (ISO)

potassium dichromate (ISO)

progesterone (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

testosterone (EXP)

tetraphene (ISO)

titanium dioxide (ISO)

toluene (EXP)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to hypoxia (IMP)

positive regulation of cardiac muscle cell apoptotic process (IMP)

positive regulation of protein phosphorylation (IDA)

regulation of protein transport (IDA)

Cellular Component

cell-cell junction (IDA)

cytoplasm (IDA)

extracellular region (IEA)

mitochondrial membrane (IDA)

plasma membrane (IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43).	Sato M, etal., J Biol Chem. 2009 Nov 6;284(45):31431-40. doi: 10.1074/jbc.M109.014068. Epub 2009 Sep 1.

Additional References at PubMed

PMID:16407149	PMID:27064407

Genomics

Comparative Map Data

Fndc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	49,686,856 - 49,769,263 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	49,686,856 - 49,769,263 (+)	Ensembl				GRCr8
mRatBN7.2	1	47,281,839 - 47,364,247 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	47,281,844 - 47,364,259 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	47,851,601 - 47,912,467 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	53,832,549 - 53,893,699 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	47,927,067 - 47,987,956 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	1	49,310,487 - 49,393,412 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	1	48,649,857 - 48,732,787 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	1	49,811,147 - 49,894,092 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	1	48,090,897 - 48,173,298 (+)	NCBI		F344_StmMcwi
Rnor_6.0	1	47,605,211 - 47,687,499 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	47,605,262 - 47,687,504 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	48,905,631 - 48,987,877 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	41,522,019 - 41,583,357 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	42,986,709 - 43,047,709 (+)	NCBI		Celera
RGSC_v3.1	1	41,524,963 - 41,632,204 (+)	NCBI
Cytogenetic Map	1	q11	NCBI

FNDC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	159,169,400 - 159,272,108 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	159,169,353 - 159,272,112 (+)	Ensembl			hg38	GRCh38
GRCh37	6	159,590,432 - 159,693,140 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	159,510,417 - 159,613,130 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	6	160,238,286 - 160,340,329 (+)	NCBI		Celera
Cytogenetic Map	6	q25.3	NCBI
HuRef	6	157,060,724 - 157,162,731 (+)	NCBI		HuRef
CHM1_1	6	159,852,853 - 159,955,448 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	160,415,015 - 160,517,654 (+)	NCBI		T2T-CHM13v2.0

Fndc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	7,957,401 - 8,046,158 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	7,957,401 - 8,046,134 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	7,738,569 - 7,827,340 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	7,738,569 - 7,827,302 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	7,931,433 - 7,997,839 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	7,576,742 - 7,643,148 (-)	NCBI		MGSCv36	mm8
Celera	17	7,616,046 - 7,681,929 (+)	NCBI		Celera
Cytogenetic Map	17	A1	NCBI
cM Map	17	4.77	NCBI

Fndc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955439	3,252,529 - 3,325,567 (-)	Ensembl
ChiLan1.0	NW_004955439	3,251,851 - 3,356,679 (-)	NCBI	ChiLan1.0	ChiLan1.0

FNDC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	179,273,306 - 179,375,519 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	177,178,432 - 177,280,551 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	157,057,862 - 157,160,066 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	162,099,887 - 162,173,981 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	162,098,598 - 162,173,981 (+)	Ensembl			panPan2	panpan1.1

FNDC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	48,501,657 - 48,602,962 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	48,501,355 - 48,602,336 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	49,344,213 - 49,445,441 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	48,688,184 - 48,789,530 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	48,687,089 - 48,789,884 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	48,562,624 - 48,663,825 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	48,433,345 - 48,534,579 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	48,993,010 - 49,094,226 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fndc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	143,483,995 - 143,568,417 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936489	10,736,182 - 10,819,754 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936489	10,760,209 - 10,820,377 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FNDC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	8,007,321 - 8,106,830 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	8,007,320 - 8,106,875 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	9,838,883 - 9,939,335 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FNDC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	86,720,558 - 86,868,978 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	86,792,712 - 86,868,321 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	59,109,150 - 59,253,765 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fndc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624929	395,705 - 460,563 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624929	395,766 - 495,288 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Fndc1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	192,027,132 - 192,090,463 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Fndc1
416 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	85
Count of miRNA genes:	74
Interacting mature miRNAs:	79
Transcripts:	ENSRNOT00000034842
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	43457837	87558729	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	7746118	52746118	Rat
1357397	Bw41	Body weight QTL 41	4.19	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	1	29409279	74409279	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	43457837	87558729	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	42122968	87122968	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	6941022	51941022	Rat
1357401	Bw43	Body weight QTL 43	3.75		body mass (VT:0001259)	body weight (CMO:0000012)	1	6909353	51909353	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
631494	Bp95	Blood pressure QTL 95	40	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	17315378	51816258	Rat
5684998	Bss101	Bone structure and strength QTL 101	3.6		tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	1	6909353	51909353	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
5684999	Bss102	Bone structure and strength QTL 102	5.5	7e-07	tibia strength trait (VT:1000284)	tibia stiffness (CMO:0001735)	1	6909353	51909353	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	43457837	87558729	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1578756	Iddm22	Insulin dependent diabetes mellitus QTL 22	2.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	20508326	65508326	Rat
631508	Sald1	Serum aldosterone level QTL 1	3.7		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	1	11684464	56684464	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	30708375	87558729	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	34565726	79565726	Rat
4889451	Eae29	Experimental allergic encephalomyelitis QTL 29	5.51		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	7746121	52746121	Rat
1558642	Prcr2	Prostate cancer resistance QTL 2	4.3		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	1	10379492	55379492	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	43509952	88509952	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	42122968	87122968	Rat
2302038	Pia31	Pristane induced arthritis QTL 31	5.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	1	12820494	57820494	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
634353	Rends2	Renal damage susceptibility QTL 2		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	1	20656420	65656420	Rat

Markers in Region

RH140011

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	87,524,568 - 87,524,748 (+)	MAPPER	mRatBN7.2
mRatBN7.2	1	47,310,743 - 47,310,923 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	47,634,121 - 47,634,300	NCBI	Rnor6.0
Rnor_6.0	4	88,606,950 - 88,607,129	NCBI	Rnor6.0
Rnor_5.0	4	153,429,639 - 153,429,818	UniSTS	Rnor5.0
Rnor_5.0	1	48,934,508 - 48,934,687	UniSTS	Rnor5.0
RGSC_v3.4	4	87,278,640 - 87,278,819	UniSTS	RGSC3.4
RGSC_v3.4	1	41,530,041 - 41,530,220	UniSTS	RGSC3.4
Celera	1	42,994,731 - 42,994,910	UniSTS
Celera	4	82,289,643 - 82,289,822	UniSTS
Cytogenetic Map	4	q24	UniSTS
Cytogenetic Map	1	q11	UniSTS

AW529829

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	47,302,698 - 47,302,896 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	47,626,076 - 47,626,273	NCBI	Rnor6.0
Rnor_5.0	1	48,926,463 - 48,926,660	UniSTS	Rnor5.0
RGSC_v3.4	1	41,521,996 - 41,522,193	UniSTS	RGSC3.4
Celera	1	42,986,686 - 42,986,883	UniSTS
RH 3.4 Map	1	541.31	UniSTS
Cytogenetic Map	1	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	16	12	150	235	91	90	65	112	59	22	458	304	11	214	81	92	31	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001038615	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001412560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288408	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288412	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288417	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	DQ256268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	LT158646	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	LT158647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000034842 ⟹ ENSRNOP00000029878

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	49,686,875 - 49,769,263 (+)	Ensembl
mRatBN7.2 Ensembl	1	47,281,853 - 47,364,259 (+)	Ensembl
Rnor_6.0 Ensembl	1	47,605,415 - 47,686,843 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000089458 ⟹ ENSRNOP00000073034

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	49,686,856 - 49,769,263 (+)	Ensembl
mRatBN7.2 Ensembl	1	47,281,853 - 47,364,259 (+)	Ensembl
Rnor_6.0 Ensembl	1	47,605,262 - 47,687,504 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094427 ⟹ ENSRNOP00000081553

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	49,707,320 - 49,769,263 (+)	Ensembl
mRatBN7.2 Ensembl	1	47,302,307 - 47,364,259 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097447 ⟹ ENSRNOP00000096698

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	49,686,856 - 49,769,263 (+)	Ensembl
mRatBN7.2 Ensembl	1	47,281,844 - 47,364,259 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099286 ⟹ ENSRNOP00000078164

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	49,686,856 - 49,769,263 (+)	Ensembl
mRatBN7.2 Ensembl	1	47,281,871 - 47,364,259 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109718 ⟹ ENSRNOP00000095147

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	49,686,856 - 49,769,263 (+)	Ensembl
mRatBN7.2 Ensembl	1	47,282,006 - 47,364,259 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000155098 ⟹ ENSRNOP00000112578

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	49,686,856 - 49,769,263 (+)	Ensembl

RefSeq Acc Id:

NM_001038615 ⟹ NP_001033704

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	49,686,875 - 49,769,263 (+)	NCBI
mRatBN7.2	1	47,281,858 - 47,364,247 (+)	NCBI
Dahl_SR_JrHsd	1	49,310,506 - 49,393,412 (+)	NCBI
Lyon_Normotensive	1	48,649,876 - 48,732,787 (+)	NCBI
Lyon_Hypertensive	1	49,811,166 - 49,894,092 (+)	NCBI
F344_StmMcwi	1	48,090,916 - 48,173,298 (+)	NCBI
Rnor_6.0	1	47,626,099 - 47,686,843 (+)	NCBI
Rnor_5.0	1	48,905,631 - 48,987,877 (+)	NCBI
RGSC_v3.4	1	41,522,019 - 41,583,357 (+)	RGD
Celera	1	42,986,709 - 43,047,709 (+)	RGD

Sequence:

show sequence

ATGGGCCTGAAGGTCACATGGGACCCACCCAAAGACGCTACCAGTAGACCCGTGGAACATTACA
ACATTGCCTATGGGAAGTCACTGAAAAGTCTTAAGTCCATCAAGGTGAATGCGGAGACACACTC
CTTCCTTATTAAAGACGTGGAAAAGGAAGTGCCCAACAAGCCCTTGCGTATGCGCGTCCGAGCC
TCAGATGACAGGCTGTCTGTTGCATGGAAGGCACCACGTCTGTCTGGAGCCAAGAGCCCACGGA
GATCTCGGGGTTTTCTTCTGGGCTATGGGGAAAGTGGCCGGAAGATGAATTATGTCCCACTGAC
CAGAGATGAGAGATCGCATGAAATTAAAAAGCTTGCCTCTGAGTCGGTGTATGTGGTCTCCCTG
CAGTCCACAAACTCCCAGGGGCAGAGTCAGCCCGTCTATAGAGCTGCCCTCACAAAGCGCAAGA
ATGCAGAAGAGGATGAACTGGATGTACCTGAAGACATTAGTGTCCGGGTCATGTCGTCTCAGTC
CGTGCTCGTGGCCTGGGTGGATCCTCTTGTGGAAAAACAGAAGAGAGTTGTTGCATCAAGACAG
TACACTGTGCGCTACCGTGAGAAGGGGGAGTCGGCCAGGTGGGATTACAAGCAAGTCTCCAACA
GGCGTGCACTGGTGGACAGCCTGATCCCAGACACCGTGTATGAATTTGCGGTCCGTATTTCACA
AGGAGAGCGAGATGGCAAGTGGAGCGCATCTGTCTTCCAGAGAACGCCGGAATCGGCTCCCACC
ACAGCGCCTGAGAACCTGAGAGTCTGGCCAGTCAACGGCAAGCCCACGGTTGTCACCGTATCCT
GGGATGCATTGCCAGAGTCTGAGGGGAAAGTGAAAGAATACATTCTTTCATATGCCCCGGCTCT
CAAACCGTTTGGAGCAAAGTCCCTCACCTTCTCTGGACATACTACTTCTGCCCTCGTGGACGGT
CTGCAGCCTGGGGAACGCTATCTGTTCAAAATCCGGGCCACAAACAGGAGAGGCCAGGGGCCAC
ACTCCAAAGCCTTCATTGTCGCTATACCAACAACCAGTTCTACTGAAGCCAGTGTCCAGCCGAA
TGGGAGAGACAATGGGAAACCTGAGAAACCACAGCAACCTTCTTCCTCTGCTCCCAAAGTTGCA
GCTTCCTCACAACACACGCCCTCAGCCAAAAATGTCAAGGATGCTCTCTCGGACTTAAAGAACA
AAATCCAGACTAATGGTGTGGCGCCCGGAAGAACCCAGCTTCACTCTAAAGTGGGTGAGCTGGA
TCCTCAGTCCACAGAAGTCACTGGCGAGGAGGAACTGGATTCCCTTGAAGATCCTCGTTCATCA
CGGTTGGAGACCCTAAACCAGAAGCAACCCTTGAGGGTACCAAGTAGATCTGGTCATGGGGCTC
TGGCTCCTGGCAGGACTCCAGCCAGGGCTGGCCTGCCAGTGCTGTCCCGCAAGGAAGGGATGGA
CAGGCGTGGCCCCTCACTGGACCCCCATCCTCATCCTAGGGTTGAACCTTCAGCTTCTTCTGCC
TACCACCAGCTCAGCTCTACAGACAATGATTCTGTGGACCGAAAGGAGGATGATCAAGCAGGAT
CCCCTGACCCTAAAGCTGCCTCTTCCGGGTCATCTCCCAAGAATCCAGGCAGGTCCAGGCCAAC
CTCTGCCCCTAGCCGCCATGCGGCTTCTAACATGCTCAGAGACAAAAGCCGGGTACACCCAGGT
ACAAAGGCAGCATCATCATCTACGTCGAGGCAGTCTCATTCTTCCACCAGTGAGGAAGACTCCA
GTGCCCAACCCTCGAGACATTTCCCACTGCATAGAGGATCTTCTACATCCCCGCTTTCTAGGGG
CTGGAAGGACCGCCAGGATACCCATGCCTCTAGTTCCCATACGACTTCCCGGACCGCCAGCTCT
TCTCATCCCTCTGCCCTGACAGAGGGCTCTGAGGAAGAGGATGGCGGCGCTGATAGTGACAGAG
CTGCAGAAGACACCATCAGGCGGGCTGAGGCCACTGCTCAGATCCAACAGACCCGGCCTGGCTT
GGGTCACTTTAGTTTGATACGGAATAAACCCTTCACTCCTCACAGCAGAAATCCAAACAGATTC
CCCAGGCTCCGTGGACCAAGGCTTCAGCCTTCTGTGTCTCCTCAGTCTACCTCAGCCTCGAAAG
TCCTCACCAGGTCTCCTTCGCTGCCAGCATCCCACACTAGGCCTGGCTCTGATGTCTATGGAGA
TGGTGAGGATGAAGAGCCTCTTCCAGCCACTGTGATCAATGACCGTACACCTTCCTATCCCAGG
CACCCAATCTCTGGCAGCTCAGACACTCTGAGAAGAGGTCCCCAGAGAGGGGCCAGCTTGTACC
GGAAGGAGCCCATCCCAGAAAACTCCAAAGCTGCTGGAGCGGATGTACCTCCTGGGGGCAGATC
CCCTCTGTCCTCCAAGGCTCAGGGCTTTCAACAGAGCACCACCGATGAAGGTGCTCCTCAAACA
TCCCCAGCATCCACCAGCCGCCAGCCGTCTCCTGCTAGACCTCCAGCATCAAGATCACAGCCCT
CCCCCGGGTCCACTGTTCCCAGAAGAATGACACCCGATCGCAGCTCAGAACTCTCTAGTTCTCA
GAGCAAGGATCGGTCACTTTCCCAGCCCAAGCTGTCCGTCGCTCACGCAGGGCATGACCACCCT
CACACTGCAAACTCCCGTGGGGTGCTCCCCTCAGCTCCCCAGAATCAGAATGAGGGTGCCCAGA
GCACCTACGAGGACAACAGCACTGAAATTGAGGGTCCAGACTCCCGGACTCCCACTCATTCAGC
TCGAGCCAAGGATACCACTCCACCCATTCTCAAACCTCGGCAGGTGGGCTCCCAGTCATGGAGC
AGTGACAACAGACCTCAGCGCAGCCAGGCAGGAGCCTCTGAAAGACCCATCCGGCCTGGCAGCA
CCCACCCACGGGCCCAGGTTCCTGGCAGGGCTGGGGTCCAGGCCACGTCAGTGAAGAAGGTCTC
ACCTTCCAAGCGGCCCCTGCCACTCGAATCTCAGCAATCGGTCTTCGCTGAGGAGGAAGAGGAA
AACGAAGGAATGTTAAAAGGCAAAGAAGATTCTCTGTCTACCTCAGTTAAAAAGTGGCCTTCTT
CCTCCTCCCCGCGGGACAAGTACGCAGACAGGAACCTTGACAAAGACAAGGCTGCCATTGGGCT
CCTTGTACAGGAAGAGAACACCGTCCCCGGAAGGCGACCACCAGGCAGCCCCGCAATAGCCTCA
CACCCATCTACCCGGCACCAGCCTCGAAATCCCGCCACTGCAAGTCCCATCGCAAACACACACT
CCTGGCCAAGGTATACCACCCGGGCCCCTTCCAGCTACTCCTCCACCACACCGATGCTCTCCTT
GCGGCAGCGGATGCAGCGGAGGTTTAGGACGCCAGTCTCGCGCCAGCCTCCACCACCCAGACCC
GTGCTTACACCAGGTTATAATGGAAGACCAAATGCAGAAGAGAACATACCTCCTGGTAGTATTG
GAAAACCAAACGGACAGAGAATTATTAATGGTCCTCAAGGAACAAAGTGGGTTGTAGACCTGGA
TCGTGGCTTGGTGTTGAATGCAGAAGGGCGGTACCTCCAAGACTCCCACGGCAATCCTCTCCGG
GTGAGACTCGGGGGAGACGGTCGCACCATCGTGGATCTTGGAGGAACCCCTATGGTGAGTCCCG
ATGGCCTCCCCCTGTTTGGGCAAGGAAGACATGGCAAACCTGTGGCCAGTGCCCAGGATAAACC
CATCTTGAGTCTTGGAGGGAAGCCCTTAGTGGGCTTGGAAGTGGTCAGAACAACCACCCAAGTT
CCTACCACAACCATGCCGCCAAGCACAACGACCACCACTGTGCCGCCCACCACAACCCTGCCGC
CCACAACCACCACCACCCGCCGGACCACCACCACCCGCCGGACCACCACCACCAGGCGTCCCAC
AACCACAACCCGAGCTACTCGCAGGACAACTACCACTACCACCACTCCGGAACCTACCACCCCC
TCTCCTACCTGTCCTCCTGGGACCCTGGAACACCGGGATGAAGCTGGCAACCTCATAATGGGCT
CAAATGGGATCCCAGAGTGCTACCTCGAGGAAGATGACTTCTCGGGCCTGGAGATAGACACGGC
ACTACCCACGGAAGAGGATTATGTTGTGTACGATGATGATTATGGACTTGAGACCACAAGGCCA
CCGACCAGCACCATGCCCTCAACCACTGCTGCCACACCGAAGGTCGTCCCAGAGCAGGGCACTG
TCAGCTCCTTCCCAGAGGAAGAATTTGACCTTGCCGGAAAGAGGCGGTTTGTTGCTCCTTACGT
GACCTACCTCAGTAAAGACCCAGCAGCCCCGTGCTCACTGACTGATGCCCTGGACCACTTCCAA
GTGGAAAGCCTGGATGAACTCATTCCAAATGACCTGACAAAGAACGATCTCCCTCCTCAGCATG
CTCCCCGGAACATTACTGTGGTCGCCATGGAAGGCTGCCACTCCTTTGTCATTGTGGACTGGAA
CAAAGCCATCCCTGGAGATGTGGTAACAGGATACCTGGTCTACAGCGCCTCTTATGAGGACTTC
ATCAGGAATAAATGGTCAACTCAGACCTCGTCAGTGACCCATTTGCCCATTGAGAACCTGAAGC
CAAACACAAGGTATTACTTCAAAGTTCAAGCGAAAAACCCTCACGGCTATGGGCCTGTCAGCCC
TTCAGTCTCATTTGTCACAGAATCAGACAATCCTCTGCTGGTTGTGAGGCCACCAGGTGGTGAG
CCCATCTGGATCCCGTTTGCTTTCAAGCATGACCCCGGCTACACTGACTGCCATGGTCGGCAGT
ATGTGAAACGGACGTGGTACAAAAAGTTTGTGGGAGTTGTTCTTTGTAATTCTCTAAGGTACAA
GATCTACCTCAGTGACAATCTCAAAGACACATTCTACAGCATTGGGGACAGCTGGGGAAGGGGT
GAAGACCATTGTCAGTTTGTGGATTCGCACCTGGATGGAAGAACGGGGCCTCAGTCTTATGTAG
AAGCCCTCCCCACCATTCAAGGCTACTATCGCCAGTACCGTCAGGAGCCCGTCAGCTTTGGACA
CATTGGATTTGGAACCCCCTATTACTATGTGGGCTGGTACGAGTGTGGAGTCTCCATCCCAGGA
AAGTGGTAA

hide sequence

RefSeq Acc Id:

NM_001412560 ⟹ NP_001399489

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	49,686,856 - 49,769,263 (+)	NCBI
mRatBN7.2	1	47,281,839 - 47,364,247 (+)	NCBI
Dahl_SR_JrHsd	1	49,310,487 - 49,393,412 (+)	NCBI
Lyon_Normotensive	1	48,649,857 - 48,732,787 (+)	NCBI
Lyon_Hypertensive	1	49,811,147 - 49,894,092 (+)	NCBI
F344_StmMcwi	1	48,090,897 - 48,173,298 (+)	NCBI

RefSeq Acc Id:

XM_063288404 ⟹ XP_063144474

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	49,686,856 - 49,769,232 (+)	NCBI

RefSeq Acc Id:

XM_063288408 ⟹ XP_063144478

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	49,686,856 - 49,769,232 (+)	NCBI

RefSeq Acc Id:

XM_063288412 ⟹ XP_063144482

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	49,686,856 - 49,769,232 (+)	NCBI

RefSeq Acc Id:

XM_063288417 ⟹ XP_063144487

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	49,686,856 - 49,769,232 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001033704	(Get FASTA)	NCBI Sequence Viewer
	NP_001399489	(Get FASTA)	NCBI Sequence Viewer
	XP_063144474	(Get FASTA)	NCBI Sequence Viewer
	XP_063144478	(Get FASTA)	NCBI Sequence Viewer
	XP_063144482	(Get FASTA)	NCBI Sequence Viewer
	XP_063144487	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABB82299	(Get FASTA)	NCBI Sequence Viewer
	CVK35887	(Get FASTA)	NCBI Sequence Viewer
	CVK35888	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000029878
	ENSRNOP00000029878.4
	ENSRNOP00000073034
	ENSRNOP00000078164
	ENSRNOP00000095147
	ENSRNOP00000096698
	ENSRNOP00000112578
GenBank Protein	Q2Q0I9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001033704 ⟸ NM_001038615
- Peptide Label:	isoform 2 precursor
- UniProtKB:	Q2Q0I9 (UniProtKB/Swiss-Prot), A0A128DZ42 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGLKVTWDPPKDATSRPVEHYNIAYGKSLKSLKSIKVNAETHSFLIKDVEKEVPNKPLRMRVRA SDDRLSVAWKAPRLSGAKSPRRSRGFLLGYGESGRKMNYVPLTRDERSHEIKKLASESVYVVSL QSTNSQGQSQPVYRAALTKRKNAEEDELDVPEDISVRVMSSQSVLVAWVDPLVEKQKRVVASRQ YTVRYREKGESARWDYKQVSNRRALVDSLIPDTVYEFAVRISQGERDGKWSASVFQRTPESAPT TAPENLRVWPVNGKPTVVTVSWDALPESEGKVKEYILSYAPALKPFGAKSLTFSGHTTSALVDG LQPGERYLFKIRATNRRGQGPHSKAFIVAIPTTSSTEASVQPNGRDNGKPEKPQQPSSSAPKVA ASSQHTPSAKNVKDALSDLKNKIQTNGVAPGRTQLHSKVGELDPQSTEVTGEEELDSLEDPRSS RLETLNQKQPLRVPSRSGHGALAPGRTPARAGLPVLSRKEGMDRRGPSLDPHPHPRVEPSASSA YHQLSSTDNDSVDRKEDDQAGSPDPKAASSGSSPKNPGRSRPTSAPSRHAASNMLRDKSRVHPG TKAASSSTSRQSHSSTSEEDSSAQPSRHFPLHRGSSTSPLSRGWKDRQDTHASSSHTTSRTASS SHPSALTEGSEEEDGGADSDRAAEDTIRRAEATAQIQQTRPGLGHFSLIRNKPFTPHSRNPNRF PRLRGPRLQPSVSPQSTSASKVLTRSPSLPASHTRPGSDVYGDGEDEEPLPATVINDRTPSYPR HPISGSSDTLRRGPQRGASLYRKEPIPENSKAAGADVPPGGRSPLSSKAQGFQQSTTDEGAPQT SPASTSRQPSPARPPASRSQPSPGSTVPRRMTPDRSSELSSSQSKDRSLSQPKLSVAHAGHDHP HTANSRGVLPSAPQNQNEGAQSTYEDNSTEIEGPDSRTPTHSARAKDTTPPILKPRQVGSQSWS SDNRPQRSQAGASERPIRPGSTHPRAQVPGRAGVQATSVKKVSPSKRPLPLESQQSVFAEEEEE NEGMLKGKEDSLSTSVKKWPSSSSPRDKYADRNLDKDKAAIGLLVQEENTVPGRRPPGSPAIAS HPSTRHQPRNPATASPIANTHSWPRYTTRAPSSYSSTTPMLSLRQRMQRRFRTPVSRQPPPPRP VLTPGYNGRPNAEENIPPGSIGKPNGQRIINGPQGTKWVVDLDRGLVLNAEGRYLQDSHGNPLR VRLGGDGRTIVDLGGTPMVSPDGLPLFGQGRHGKPVASAQDKPILSLGGKPLVGLEVVRTTTQV PTTTMPPSTTTTTVPPTTTLPPTTTTTRRTTTTRRTTTTRRPTTTTRATRRTTTTTTTPEPTTP SPTCPPGTLEHRDEAGNLIMGSNGIPECYLEEDDFSGLEIDTALPTEEDYVVYDDDYGLETTRP PTSTMPSTTAATPKVVPEQGTVSSFPEEEFDLAGKRRFVAPYVTYLSKDPAAPCSLTDALDHFQ VESLDELIPNDLTKNDLPPQHAPRNITVVAMEGCHSFVIVDWNKAIPGDVVTGYLVYSASYEDF IRNKWSTQTSSVTHLPIENLKPNTRYYFKVQAKNPHGYGPVSPSVSFVTESDNPLLVVRPPGGE PIWIPFAFKHDPGYTDCHGRQYVKRTWYKKFVGVVLCNSLRYKIYLSDNLKDTFYSIGDSWGRG EDHCQFVDSHLDGRTGPQSYVEALPTIQGYYRQYRQEPVSFGHIGFGTPYYYVGWYECGVSIPG KW hide sequence

Ensembl Acc Id:

ENSRNOP00000073034 ⟸ ENSRNOT00000089458

Ensembl Acc Id:

ENSRNOP00000029878 ⟸ ENSRNOT00000034842

Ensembl Acc Id:

ENSRNOP00000096698 ⟸ ENSRNOT00000097447

Ensembl Acc Id:

ENSRNOP00000078164 ⟸ ENSRNOT00000099286

Ensembl Acc Id:

ENSRNOP00000081553 ⟸ ENSRNOT00000094427

Ensembl Acc Id:

ENSRNOP00000095147 ⟸ ENSRNOT00000109718

RefSeq Acc Id:	NP_001399489 ⟸ NM_001412560
- Peptide Label:	isoform 1 precursor
- UniProtKB:	A0A0G2K4G5 (UniProtKB/TrEMBL), A0A8I5ZT63 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063144478 ⟸ XM_063288408
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6GLH3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063144474 ⟸ XM_063288404
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZT63 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063144482 ⟸ XM_063288412
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5Y884 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063144487 ⟸ XM_063288417
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6AMB4 (UniProtKB/TrEMBL), A0A8I5Y884 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000112578 ⟸ ENSRNOT00000155098

Protein Domains

Fibronectin type-III

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q2Q0I9-F1-model_v2	AlphaFold	Q2Q0I9	1-1779	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689621

Promoter ID:

EPDNEW_R134

Type:

multiple initiation site

Name:

Fndc1_1

Description:

fibronectin type III domain containing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	47,605,235 - 47,605,295	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310640	AgrOrtholog
BioCyc Gene	G2FUF-61602	BioCyc
Ensembl Genes	ENSRNOG00000030210	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000034842	ENTREZGENE
	ENSRNOT00000034842.5	UniProtKB/Swiss-Prot
	ENSRNOT00000089458	ENTREZGENE
	ENSRNOT00000097447	ENTREZGENE
	ENSRNOT00000099286	ENTREZGENE
	ENSRNOT00000109718	ENTREZGENE
	ENSRNOT00000155098	ENTREZGENE
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot
InterPro	FN3_dom	UniProtKB/Swiss-Prot
	FN3_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot
	TARSH/FNDC1_C	UniProtKB/Swiss-Prot
KEGG Report	rno:308099	UniProtKB/Swiss-Prot
NCBI Gene	308099	ENTREZGENE
PANTHER	FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1	UniProtKB/Swiss-Prot
	TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING	UniProtKB/Swiss-Prot
Pfam	fn3	UniProtKB/Swiss-Prot
	TARSH_C	UniProtKB/Swiss-Prot
PhenoGen	Fndc1	PhenoGen
PROSITE	FN3	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000030210	RatGTEx
SMART	FN3	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF49265	UniProtKB/Swiss-Prot
UniProt	A0A0G2K4G5	ENTREZGENE, UniProtKB/TrEMBL
	A0A128DZ42	ENTREZGENE, UniProtKB/TrEMBL
	A0A128E118_RAT	UniProtKB/TrEMBL
	A0A8I5Y884	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZT63	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AMB4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GLH3	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LNH6_RAT	UniProtKB/TrEMBL
	FNDC1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Fndc1	fibronectin type III domain containing 1			Symbol and Name updated	1299863	APPROVED
2006-03-07	Fndc1	fibronectin type III domain containing 1	Fndc1_predicted	fibronectin type III domain containing 1 (predicted)	Symbol and Name status set to approved	1299863	APPROVED
2005-01-12	Fndc1_predicted	fibronectin type III domain containing 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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