Siae (sialic acid acetylesterase) - Rat Genome Database

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Gene: Siae (sialic acid acetylesterase) Rattus norvegicus
Analyze
Symbol: Siae
Name: sialic acid acetylesterase
RGD ID: 1310431
Description: Predicted to enable sialate O-acetylesterase activity. Predicted to be involved in carbohydrate metabolic process and regulation of immune system process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in autoimmune disease. Orthologous to human SIAE (sialic acid acetylesterase); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC363045; RGD1310431; sialate O-acetylesterase; sialic acid-specific 9-O-acetylesterase; similar to sialic-acid O-acetylesterase; yolk sac protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8845,507,465 - 45,542,740 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl845,507,326 - 45,542,740 (+)EnsemblGRCr8
mRatBN7.2837,318,724 - 37,354,004 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl837,318,747 - 37,353,996 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx841,335,011 - 41,370,367 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0839,618,074 - 39,653,431 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0837,480,954 - 37,516,313 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd845,574,646 - 45,609,996 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive847,745,013 - 47,780,363 (+)NCBILyon_Normotensive
Lyon_Hypertensive846,287,578 - 46,322,928 (+)NCBILyon_Hypertensive
F344_StmMcwi837,619,012 - 37,654,369 (+)NCBIF344_StmMcwi
Rnor_6.0840,078,269 - 40,113,514 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl840,078,269 - 40,113,514 (+)Ensemblrn6Rnor6.0
Rnor_5.0840,079,093 - 40,114,338 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4838,854,154 - 38,889,452 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera837,101,383 - 37,136,604 (-)NCBICelera
RGSC_v3.1838,862,919 - 38,896,428 (+)NCBI
Cytogenetic Map8q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
actinomycin D  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
epoxiconazole  (ISO)
erianin  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
formaldehyde  (ISO)
glafenine  (EXP)
ivermectin  (ISO)
lead diacetate  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylphenidate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nimesulide  (EXP)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
lysosome  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2808434   PMID:8486688   PMID:12477932   PMID:16502470   PMID:19056867   PMID:20555325   PMID:23308225   PMID:23376485   PMID:23533145   PMID:29514215  


Genomics

Comparative Map Data
Siae
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8845,507,465 - 45,542,740 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl845,507,326 - 45,542,740 (+)EnsemblGRCr8
mRatBN7.2837,318,724 - 37,354,004 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl837,318,747 - 37,353,996 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx841,335,011 - 41,370,367 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0839,618,074 - 39,653,431 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0837,480,954 - 37,516,313 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd845,574,646 - 45,609,996 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive847,745,013 - 47,780,363 (+)NCBILyon_Normotensive
Lyon_Hypertensive846,287,578 - 46,322,928 (+)NCBILyon_Hypertensive
F344_StmMcwi837,619,012 - 37,654,369 (+)NCBIF344_StmMcwi
Rnor_6.0840,078,269 - 40,113,514 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl840,078,269 - 40,113,514 (+)Ensemblrn6Rnor6.0
Rnor_5.0840,079,093 - 40,114,338 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4838,854,154 - 38,889,452 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera837,101,383 - 37,136,604 (-)NCBICelera
RGSC_v3.1838,862,919 - 38,896,428 (+)NCBI
Cytogenetic Map8q22NCBI
SIAE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811124,633,113 - 124,676,303 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11124,633,113 - 124,695,707 (-)Ensemblhg38GRCh38
GRCh3711124,503,009 - 124,546,199 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,010,903 - 124,048,927 (-)NCBIBuild 36Build 36hg18NCBI36
Celera11121,665,869 - 121,703,894 (-)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11120,448,144 - 120,488,613 (-)NCBIHuRef
CHM1_111124,391,816 - 124,432,334 (-)NCBICHM1_1
T2T-CHM13v2.011124,661,771 - 124,704,961 (-)NCBIT2T-CHM13v2.0
Siae
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39937,525,117 - 37,559,554 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl937,466,994 - 37,560,951 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38937,613,821 - 37,648,258 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl937,555,698 - 37,649,655 (+)Ensemblmm10GRCm38
MGSCv37937,421,432 - 37,455,903 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36937,363,518 - 37,397,989 (+)NCBIMGSCv36mm8
Celera934,830,942 - 34,865,371 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.79NCBI
Siae
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541225,703,591 - 25,792,252 (-)Ensembl
ChiLan1.0NW_00495541225,704,024 - 25,741,646 (-)NCBIChiLan1.0ChiLan1.0
SIAE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29125,331,987 - 125,371,605 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111126,436,869 - 126,476,476 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011119,463,554 - 119,503,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111123,378,866 - 123,416,935 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11123,378,866 - 123,416,935 (-)EnsemblpanPan2panpan1.1
SIAE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.159,719,444 - 9,770,574 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl59,731,394 - 9,769,227 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha59,764,289 - 9,815,399 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.059,659,068 - 9,710,228 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl59,621,463 - 9,754,225 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.159,731,219 - 9,782,258 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.059,701,662 - 9,752,761 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.059,750,359 - 9,789,276 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Siae
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947106,860,332 - 106,894,503 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367431,109,211 - 1,142,807 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367431,105,461 - 1,142,028 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIAE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl951,879,224 - 51,918,827 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1951,879,220 - 51,918,974 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2957,397,132 - 57,436,360 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SIAE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11115,782,624 - 115,822,707 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1115,782,964 - 115,820,284 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604310,296,759 - 10,334,554 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Siae
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624927637,175 - 678,780 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624927636,134 - 678,367 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Siae
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1833,774,098 - 33,809,575 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Siae
264 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:196
Count of miRNA genes:145
Interacting mature miRNAs:171
Transcripts:ENSRNOT00000044293
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)84447792689477926Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625851589833Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)83776085958991895Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)83776085961459705Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84444783789447837Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625867378345Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)83412590255607752Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)84447504389475043Rat
70206Alc20Alcohol consumption QTL 202drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)83910625849610361Rat

Markers in Region
AI227734  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2837,353,747 - 37,353,899 (+)MAPPERmRatBN7.2
Rnor_6.0840,113,266 - 40,113,417NCBIRnor6.0
Rnor_5.0840,114,090 - 40,114,241UniSTSRnor5.0
RGSC_v3.4838,889,204 - 38,889,355UniSTSRGSC3.4
Celera837,101,480 - 37,101,631UniSTS
RH 3.4 Map8342.7UniSTS
Cytogenetic Map8q21UniSTS
AI229581  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2837,352,174 - 37,352,332 (+)MAPPERmRatBN7.2
Rnor_6.0840,111,693 - 40,111,850NCBIRnor6.0
Rnor_5.0840,112,517 - 40,112,674UniSTSRnor5.0
RGSC_v3.4838,887,631 - 38,887,788UniSTSRGSC3.4
Celera837,103,047 - 37,103,204UniSTS
RH 3.4 Map8341.3UniSTS
Cytogenetic Map8q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000044293   ⟹   ENSRNOP00000042202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl845,507,326 - 45,542,681 (+)Ensembl
mRatBN7.2 Ensembl837,318,747 - 37,353,996 (+)Ensembl
Rnor_6.0 Ensembl840,078,269 - 40,113,514 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118472   ⟹   ENSRNOP00000081206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl845,516,733 - 45,542,740 (+)Ensembl
mRatBN7.2 Ensembl837,328,228 - 37,353,996 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000163574   ⟹   ENSRNOP00000112523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl845,520,676 - 45,542,740 (+)Ensembl
RefSeq Acc Id: NM_001108759   ⟹   NP_001102229
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8845,507,490 - 45,542,740 (+)NCBI
mRatBN7.2837,318,747 - 37,353,996 (+)NCBI
Dahl_SR_JrHsd845,574,646 - 45,609,996 (+)NCBI
Lyon_Normotensive847,745,013 - 47,780,363 (+)NCBI
Lyon_Hypertensive846,287,578 - 46,322,928 (+)NCBI
F344_StmMcwi837,619,012 - 37,654,369 (+)NCBI
Rnor_6.0840,078,269 - 40,113,514 (+)NCBI
Rnor_5.0840,079,093 - 40,114,338 (+)NCBI
RGSC_v3.4838,854,154 - 38,889,452 (+)RGD
Celera837,101,383 - 37,136,604 (-)RGD
Sequence:
RefSeq Acc Id: XM_039081721   ⟹   XP_038937649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8845,520,846 - 45,542,683 (+)NCBI
mRatBN7.2837,331,609 - 37,354,004 (+)NCBI
RefSeq Acc Id: XR_010053992
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8845,507,465 - 45,537,264 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102229 (Get FASTA)   NCBI Sequence Viewer  
  XP_038937649 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL84072 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000042202
  ENSRNOP00000112523
GenBank Protein P82450 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001102229   ⟸   NM_001108759
- Peptide Label: precursor
- UniProtKB: A6KRK4 (UniProtKB/TrEMBL),   A0A0A0MY22 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000042202   ⟸   ENSRNOT00000044293
RefSeq Acc Id: XP_038937649   ⟸   XM_039081721
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G7N7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000081206   ⟸   ENSRNOT00000118472
Ensembl Acc Id: ENSRNOP00000112523   ⟸   ENSRNOT00000163574

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P82450-F1-model_v2 AlphaFold P82450 1-542 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695865
Promoter ID:EPDNEW_R6390
Type:initiation region
Name:Siae_1
Description:sialic acid acetylesterase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0840,078,258 - 40,078,318EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310431 AgrOrtholog
BioCyc Gene G2FUF-31053 BioCyc
Ensembl Genes ENSRNOG00000031266 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000044293 ENTREZGENE
  ENSRNOT00000163574 ENTREZGENE
Gene3D-CATH 3.40.50.1110 UniProtKB/Swiss-Prot
InterPro SGNH_hydro_sf UniProtKB/Swiss-Prot
  SIAE UniProtKB/Swiss-Prot
NCBI Gene 363045 ENTREZGENE
PANTHER PTHR22901 UniProtKB/Swiss-Prot
  SIALATE O-ACETYLESTERASE UniProtKB/Swiss-Prot
PhenoGen Siae PhenoGen
RatGTEx ENSRNOG00000031266 RatGTEx
Superfamily-SCOP SGNH hydrolase UniProtKB/Swiss-Prot
UniProt A0A0A0MY22 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G7N7 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0MAX8_RAT UniProtKB/TrEMBL
  A6KRK4 ENTREZGENE, UniProtKB/TrEMBL
  P82450 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Siae  sialic acid acetylesterase   Siae_predicted  sialic acid acetylesterase (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Siae_predicted  sialic acid acetylesterase (predicted)  RGD1310431_predicted  similar to sialic-acid O-acetylesterase (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1310431_predicted  similar to sialic-acid O-acetylesterase (predicted)  LOC363045_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC363045_predicted  similar to sialic-acid O-acetylesterase (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL