Evc2 (EvC ciliary complex subunit 2) - Rat Genome Database

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Pathways
Gene: Evc2 (EvC ciliary complex subunit 2) Rattus norvegicus
Analyze
Symbol: Evc2
Name: EvC ciliary complex subunit 2
RGD ID: 1310417
Description: Predicted to be involved in smoothened signaling pathway. Predicted to be located in cilium and nucleus. Predicted to be part of plasma membrane protein complex. Predicted to be active in ciliary membrane. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome and Weyers acrofacial dysostosis. Orthologous to human EVC2 (EvC ciliary complex subunit 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ellis van Creveld syndrome 2; Ellis van Creveld syndrome 2 (limbin); Ellis van Creveld syndrome 2 homolog; Ellis van Creveld syndrome 2 homolog (human); limbin; LOC289711
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81477,591,581 - 77,679,286 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1477,592,560 - 77,679,262 (-)EnsemblGRCr8
mRatBN7.21473,366,832 - 73,454,539 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1473,367,963 - 73,454,516 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1477,813,287 - 77,900,110 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01479,054,123 - 79,140,954 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01475,496,843 - 75,585,588 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01478,128,620 - 78,212,394 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1478,129,749 - 78,211,931 (-)Ensemblrn6Rnor6.0
Rnor_5.01478,102,369 - 78,186,380 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41478,915,869 - 79,018,416 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1472,323,360 - 72,407,276 (-)NCBICelera
RGSC_v3.11478,918,262 - 79,021,918 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
ciliary membrane  (IBA,IEA,ISO)
cilium  (IEA,ISO)
nucleus  (IEA,ISO)
plasma membrane  (IEA)
plasma membrane protein complex  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Mutations in two nonhomologous genes in a head-to-head configuration cause Ellis-van Creveld syndrome. Ruiz-Perez VL, etal., Am J Hum Genet. 2003 Mar;72(3):728-32. Epub 2003 Feb 4.
7. Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis. Ruiz-Perez VL, etal., Nat Genet 2000 Mar;24(3):283-6.
Additional References at PubMed
PMID:21356043   PMID:21630459   PMID:24582806  


Genomics

Comparative Map Data
Evc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81477,591,581 - 77,679,286 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1477,592,560 - 77,679,262 (-)EnsemblGRCr8
mRatBN7.21473,366,832 - 73,454,539 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1473,367,963 - 73,454,516 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1477,813,287 - 77,900,110 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01479,054,123 - 79,140,954 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01475,496,843 - 75,585,588 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01478,128,620 - 78,212,394 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1478,129,749 - 78,211,931 (-)Ensemblrn6Rnor6.0
Rnor_5.01478,102,369 - 78,186,380 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41478,915,869 - 79,018,416 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1472,323,360 - 72,407,276 (-)NCBICelera
RGSC_v3.11478,918,262 - 79,021,918 (-)NCBI
Cytogenetic Map14q21NCBI
EVC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3845,529,011 - 5,709,548 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl45,542,772 - 5,709,548 (-)Ensemblhg38GRCh38
GRCh3745,564,166 - 5,711,275 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3645,615,051 - 5,761,195 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3445,682,218 - 5,829,347NCBI
Celera45,461,794 - 5,609,016 (-)NCBICelera
Cytogenetic Map4p16.2NCBI
HuRef45,499,944 - 5,646,754 (-)NCBIHuRef
CHM1_145,562,086 - 5,709,281 (-)NCBICHM1_1
T2T-CHM13v2.045,498,451 - 5,681,203 (-)NCBIT2T-CHM13v2.0
Evc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39537,495,801 - 37,582,399 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl537,495,843 - 37,582,399 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38537,338,478 - 37,425,055 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl537,338,499 - 37,425,055 (+)Ensemblmm10GRCm38
MGSCv37537,729,717 - 37,816,293 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36537,626,757 - 37,713,304 (+)NCBIMGSCv36mm8
Celera534,789,138 - 34,876,031 (+)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.15NCBI
Evc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555144,333,066 - 4,430,902 (+)Ensembl
ChiLan1.0NW_0049555144,332,624 - 4,430,844 (+)NCBIChiLan1.0ChiLan1.0
EVC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v235,825,894 - 5,973,158 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan145,758,919 - 5,906,244 (-)NCBINHGRI_mPanPan1
PanPan1.145,635,151 - 5,782,657 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl45,635,151 - 5,782,657 (-)EnsemblpanPan2panpan1.1
EVC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1370,809,649 - 70,935,391 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl370,810,048 - 70,935,860 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha373,359,905 - 73,486,132 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0371,570,145 - 71,696,809 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl371,570,137 - 71,696,931 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1370,840,813 - 70,967,348 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0371,001,475 - 71,128,276 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0371,379,001 - 71,505,644 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Evc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528564,133,787 - 64,236,353 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647717,837,964 - 17,937,975 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647717,835,479 - 17,938,014 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EVC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl84,893,217 - 5,023,644 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.184,893,480 - 5,023,655 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.282,357,858 - 2,369,271 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EVC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12741,703,062 - 41,851,231 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2741,703,491 - 41,850,904 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604788,496,081 - 88,644,864 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Evc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475522,331,117 - 22,428,873 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475522,326,321 - 22,429,141 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Evc2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11167,731,686 - 67,818,857 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Evc2
545 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:259
Count of miRNA genes:158
Interacting mature miRNAs:178
Transcripts:ENSRNOT00000009914
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat

Markers in Region
D14Arb10  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81477,640,071 - 77,640,324 (+)Marker Load Pipeline
mRatBN7.21473,415,323 - 73,415,578 (+)MAPPERmRatBN7.2
Rnor_6.01478,172,765 - 78,173,017NCBIRnor6.0
Rnor_5.01478,146,760 - 78,147,012UniSTSRnor5.0
RGSC_v3.41478,978,644 - 78,978,896UniSTSRGSC3.4
Celera1472,367,960 - 72,368,212UniSTS
SHRSP x BN Map1443.03RGD
SHRSP x BN Map1443.03UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 12 67 160 91 90 59 53 59 6 314 153 11 139 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000009914   ⟹   ENSRNOP00000009914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1477,592,709 - 77,679,262 (-)Ensembl
mRatBN7.2 Ensembl1473,367,963 - 73,454,516 (-)Ensembl
Rnor_6.0 Ensembl1478,129,749 - 78,211,931 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000166300   ⟹   ENSRNOP00000103995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1477,592,560 - 77,679,262 (-)Ensembl
RefSeq Acc Id: NM_001106012   ⟹   NP_001099482
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81477,592,702 - 77,679,262 (-)NCBI
mRatBN7.21473,367,956 - 73,454,516 (-)NCBI
Rnor_6.01478,129,742 - 78,211,931 (-)NCBI
Rnor_5.01478,102,369 - 78,186,380 (-)NCBI
RGSC_v3.41478,915,869 - 79,018,416 (-)RGD
Celera1472,323,360 - 72,407,276 (-)RGD
Sequence:
RefSeq Acc Id: XM_017599114   ⟹   XP_017454603
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81477,591,581 - 77,679,166 (-)NCBI
mRatBN7.21473,366,832 - 73,454,408 (-)NCBI
Rnor_6.01478,128,620 - 78,211,772 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091722   ⟹   XP_038947650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81477,591,581 - 77,679,286 (-)NCBI
mRatBN7.21473,366,832 - 73,454,539 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001099482 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454603 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947650 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM00024 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009914
  ENSRNOP00000009914.4
  ENSRNOP00000103995
  ENSRNOP00000103995.1
RefSeq Acc Id: NP_001099482   ⟸   NM_001106012
- UniProtKB: D3ZWN3 (UniProtKB/TrEMBL),   A6IJW0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454603   ⟸   XM_017599114
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000009914   ⟸   ENSRNOT00000009914
RefSeq Acc Id: XP_038947650   ⟸   XM_039091722
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000103995   ⟸   ENSRNOT00000166300

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZWN3-F1-model_v2 AlphaFold D3ZWN3 1-1217 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699373
Promoter ID:EPDNEW_R9898
Type:initiation region
Name:Evc2_1
Description:EvC ciliary complex subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01478,211,952 - 78,212,012EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310417 AgrOrtholog
BioCyc Gene G2FUF-15357 BioCyc
Ensembl Genes ENSRNOG00000007025 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009914 ENTREZGENE
  ENSRNOT00000009914.8 UniProtKB/TrEMBL
  ENSRNOT00000166300 ENTREZGENE
  ENSRNOT00000166300.1 UniProtKB/TrEMBL
InterPro EVC2-like UniProtKB/TrEMBL
  Limbin/Ellis-van_Creveld UniProtKB/TrEMBL
KEGG Report rno:289711 UniProtKB/TrEMBL
NCBI Gene 289711 ENTREZGENE
PANTHER LIMBIN UniProtKB/TrEMBL
  PTHR16795 UniProtKB/TrEMBL
Pfam EVC2_like UniProtKB/TrEMBL
PhenoGen Evc2 PhenoGen
RatGTEx ENSRNOG00000007025 RatGTEx
UniProt A0ABK0L3S4_RAT UniProtKB/TrEMBL
  A6IJW0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZWN3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-19 Evc2  EvC ciliary complex subunit 2  Evc2  Ellis van Creveld syndrome 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-14 Evc2  Ellis van Creveld syndrome 2  Evc2  Ellis van Creveld syndrome 2 homolog (human)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Evc2  Ellis van Creveld syndrome 2 homolog (human)   Evc2_predicted  Ellis van Creveld syndrome 2 homolog (human) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Evc2_predicted  Ellis van Creveld syndrome 2 homolog (human) (predicted)    Ellis van Creveld syndrome 2 (limbin) (predicted)  Name updated 1299863 APPROVED
2005-01-12 Evc2_predicted  Ellis van Creveld syndrome 2 (limbin) (predicted)      Symbol and Name status set to approved 70820 APPROVED