Pptc7 (protein phosphatase targeting COQ7) - Rat Genome Database

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Pathways
Gene: Pptc7 (protein phosphatase targeting COQ7) Rattus norvegicus
Analyze
Symbol: Pptc7
Name: protein phosphatase targeting COQ7
RGD ID: 1310383
Description: Predicted to enable protein serine/threonine phosphatase activity and protein-macromolecule adaptor activity. Predicted to be involved in positive regulation of ubiquinone biosynthetic process. Predicted to act upstream of or within mitophagy and negative regulation of mitophagy. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrial outer membrane. Orthologous to human PPTC7 (protein phosphatase targeting COQ7); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC304488; protein phosphatase PTC7 homolog; PTC7 protein phosphatase homolog; PTC7 protein phosphatase homolog (S. cerevisiae); RGD1310383; similar to T-cell activation protein phosphatase 2C; T-cell activation protein phosphatase 2C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,910,728 - 39,949,101 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1239,910,742 - 39,949,101 (-)EnsemblGRCr8
mRatBN7.21234,249,963 - 34,288,339 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1234,249,977 - 34,288,339 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1235,422,353 - 35,460,753 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01236,033,599 - 36,071,984 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,086,069 - 35,124,449 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,731,107 - 39,769,480 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,731,121 - 39,769,480 (-)Ensemblrn6Rnor6.0
Rnor_5.01241,612,134 - 41,650,388 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41235,445,302 - 35,483,671 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1235,920,779 - 35,959,227 (-)NCBICelera
RGSC_v3.11235,311,411 - 35,347,052 (-)NCBI
Cytogenetic Map12q16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
copper(II) sulfate  (ISO)
Dibutyl phosphate  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenthion  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
GSK-J4  (ISO)
hydroquinone  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (EXP)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
tamoxifen  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17728463   PMID:18614015   PMID:25931508   PMID:30267671   PMID:34800366  


Genomics

Comparative Map Data
Pptc7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,910,728 - 39,949,101 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1239,910,742 - 39,949,101 (-)EnsemblGRCr8
mRatBN7.21234,249,963 - 34,288,339 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1234,249,977 - 34,288,339 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1235,422,353 - 35,460,753 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01236,033,599 - 36,071,984 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,086,069 - 35,124,449 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,731,107 - 39,769,480 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,731,121 - 39,769,480 (-)Ensemblrn6Rnor6.0
Rnor_5.01241,612,134 - 41,650,388 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41235,445,302 - 35,483,671 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1235,920,779 - 35,959,227 (-)NCBICelera
RGSC_v3.11235,311,411 - 35,347,052 (-)NCBI
Cytogenetic Map12q16NCBI
PPTC7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812110,533,245 - 110,583,318 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12110,533,245 - 110,583,383 (-)Ensemblhg38GRCh38
GRCh3712110,971,050 - 111,021,123 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612109,456,620 - 109,505,447 (-)NCBIBuild 36Build 36hg18NCBI36
Celera12110,598,937 - 110,647,770 (-)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12107,990,424 - 108,038,697 (-)NCBIHuRef
CHM1_112110,939,903 - 110,988,724 (-)NCBICHM1_1
T2T-CHM13v2.012110,510,939 - 110,561,010 (-)NCBIT2T-CHM13v2.0
Pptc7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395122,422,461 - 122,462,344 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5122,422,428 - 122,462,344 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385122,284,398 - 122,324,281 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5122,284,365 - 122,324,281 (+)Ensemblmm10GRCm38
MGSCv375122,734,407 - 122,774,290 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365122,545,015 - 122,584,898 (+)NCBIMGSCv36mm8
Celera5119,366,872 - 119,406,757 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.28NCBI
Pptc7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554827,445,218 - 7,484,952 (-)Ensembl
ChiLan1.0NW_0049554827,445,218 - 7,484,939 (-)NCBIChiLan1.0ChiLan1.0
PPTC7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210118,594,143 - 118,644,387 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112118,590,546 - 118,639,422 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012108,103,217 - 108,152,088 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112111,499,419 - 111,547,288 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12111,499,419 - 111,548,285 (-)EnsemblpanPan2panpan1.1
PPTC7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,345,690 - 8,383,902 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,349,453 - 8,383,617 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha268,509,240 - 8,547,247 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0268,606,290 - 8,642,035 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,603,767 - 8,642,254 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1268,562,698 - 8,600,724 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0268,621,651 - 8,659,686 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0268,577,006 - 8,615,042 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pptc7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118155,947,536 - 155,988,201 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365583,490,808 - 3,532,345 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365583,491,225 - 3,531,886 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPTC7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1431,906,262 - 31,946,554 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11431,905,379 - 31,946,555 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21433,827,421 - 33,868,659 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPTC7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111105,774,912 - 105,823,882 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11105,778,596 - 105,823,836 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037139,293,778 - 139,344,004 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pptc7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474721,320,617 - 21,358,904 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474721,320,525 - 21,358,830 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pptc7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11631,525,594 - 31,564,035 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pptc7
242 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:752
Count of miRNA genes:305
Interacting mature miRNAs:393
Transcripts:ENSRNOT00000036137
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122977552242298555Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)123424347543352593Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat

Markers in Region
BF387255  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,277,240 - 34,277,391 (+)MAPPERmRatBN7.2
Rnor_6.01239,758,385 - 39,758,535NCBIRnor6.0
Rnor_5.01241,639,293 - 41,639,443UniSTSRnor5.0
RGSC_v3.41235,472,576 - 35,472,726UniSTSRGSC3.4
Celera1235,948,134 - 35,948,284UniSTS
RH 3.4 Map12606.7UniSTS
Cytogenetic Map12q16UniSTS
RH137022  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,249,708 - 34,249,877 (+)MAPPERmRatBN7.2
Rnor_6.01239,730,853 - 39,731,021NCBIRnor6.0
Rnor_5.01241,611,880 - 41,612,048UniSTSRnor5.0
RGSC_v3.41235,445,048 - 35,445,216UniSTSRGSC3.4
Celera1235,920,525 - 35,920,693UniSTS
RH 3.4 Map12594.0UniSTS
Cytogenetic Map12q16UniSTS
AI502108  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,250,754 - 34,250,938 (+)MAPPERmRatBN7.2
Rnor_6.01239,731,899 - 39,732,082NCBIRnor6.0
Rnor_5.01241,612,926 - 41,613,109UniSTSRnor5.0
RGSC_v3.41235,446,094 - 35,446,277UniSTSRGSC3.4
Celera1235,921,571 - 35,921,754UniSTS
RH 3.4 Map12605.8UniSTS
Cytogenetic Map12q16UniSTS
G44856  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,284,469 - 34,284,743 (+)MAPPERmRatBN7.2
Rnor_6.01239,765,611 - 39,765,884NCBIRnor6.0
Rnor_5.01241,646,519 - 41,646,792UniSTSRnor5.0
RGSC_v3.41235,479,802 - 35,480,075UniSTSRGSC3.4
Celera1235,955,360 - 35,955,631UniSTS
Cytogenetic Map12q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000036137   ⟹   ENSRNOP00000030546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1239,910,742 - 39,949,101 (-)Ensembl
mRatBN7.2 Ensembl1234,249,977 - 34,288,339 (-)Ensembl
Rnor_6.0 Ensembl1239,731,121 - 39,769,480 (-)Ensembl
RefSeq Acc Id: NM_001107141   ⟹   NP_001100611
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,910,728 - 39,949,101 (-)NCBI
mRatBN7.21234,249,963 - 34,288,339 (-)NCBI
Rnor_6.01239,731,107 - 39,769,480 (-)NCBI
Rnor_5.01241,612,134 - 41,650,388 (-)NCBI
RGSC_v3.41235,445,302 - 35,483,671 (-)RGD
Celera1235,920,779 - 35,959,227 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100611 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM13696 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030546
  ENSRNOP00000030546.4
RefSeq Acc Id: NP_001100611   ⟸   NM_001107141
- UniProtKB: D4A520 (UniProtKB/TrEMBL),   A6J1A7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030546   ⟸   ENSRNOT00000036137
Protein Domains
PPM-type phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A520-F1-model_v2 AlphaFold D4A520 1-307 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698649
Promoter ID:EPDNEW_R9174
Type:multiple initiation site
Name:Pptc7_1
Description:PTC7 protein phosphatase homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01239,769,473 - 39,769,533EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310383 AgrOrtholog
BioCyc Gene G2FUF-19242 BioCyc
Ensembl Genes ENSRNOG00000021440 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036137 ENTREZGENE
  ENSRNOT00000036137.6 UniProtKB/TrEMBL
Gene3D-CATH 3.60.40.10 UniProtKB/TrEMBL
InterPro PP2C-related UniProtKB/TrEMBL
  PPM-type_dom_sf UniProtKB/TrEMBL
  PPTC7 UniProtKB/TrEMBL
KEGG Report rno:304488 UniProtKB/TrEMBL
NCBI Gene 304488 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE PTC7 HOMOLOG UniProtKB/TrEMBL
  PTHR12320 UniProtKB/TrEMBL
Pfam SpoIIE UniProtKB/TrEMBL
PhenoGen Pptc7 PhenoGen
PROSITE PPM_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021440 RatGTEx
SMART PP2C_SIG UniProtKB/TrEMBL
  PP2Cc UniProtKB/TrEMBL
Superfamily-SCOP PP2C-related UniProtKB/TrEMBL
UniProt A6J1A7 ENTREZGENE, UniProtKB/TrEMBL
  D4A520 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Pptc7  protein phosphatase targeting COQ7  Pptc7  PTC7 protein phosphatase homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-17 Pptc7  PTC7 protein phosphatase homolog  Pptc7  PTC7 protein phosphatase homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-27 Pptc7  PTC7 protein phosphatase homolog (S. cerevisiae)  RGD1310383_predicted  similar to T-cell activation protein phosphatase 2C (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1310383_predicted  similar to T-cell activation protein phosphatase 2C (predicted)  LOC304488_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC304488_predicted  similar to T-cell activation protein phosphatase 2C (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL