Nfx1 (nuclear transcription factor, X-box binding 1)

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Gene: Nfx1 (nuclear transcription factor, X-box binding 1) Rattus norvegicus

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Symbol:

Nfx1

Name:

nuclear transcription factor, X-box binding 1

RGD ID:

1310277

Description:

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and protein autoubiquitination. Predicted to act upstream of or within negative regulation of MHC class II biosynthetic process. Predicted to be active in nucleus. Orthologous to human NFX1 (nuclear transcription factor, X-box binding 1); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC313166; transcriptional repressor NF-X1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NFX1 (nuclear transcription factor, X-box binding 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nfx1 (nuclear transcription factor, X-box binding 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nfx1 (nuclear transcription factor, X-box binding 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NFX1 (nuclear transcription factor, X-box binding 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NFX1 (nuclear transcription factor, X-box binding 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nfx1 (nuclear transcription factor, X-box binding 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NFX1 (nuclear transcription factor, X-box binding 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NFX1 (nuclear transcription factor, X-box binding 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nfx1 (nuclear transcription factor, X-box binding 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Nfx1 (nuclear transcription factor, X-box binding 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RHOG (ras homolog family member G)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	NFX1 (nuclear transcription factor, X-box binding 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nfx1 (nuclear transcription factor, X-box binding 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-10f23.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	FAP1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	FAP1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nfx-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	stc	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nfx1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	60,900,140 - 60,958,889 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	60,901,217 - 60,958,889 (+)	Ensembl				GRCr8
mRatBN7.2	5	56,104,945 - 56,162,912 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	56,105,234 - 56,162,912 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	58,071,542 - 58,129,118 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	59,890,692 - 59,948,268 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	59,885,062 - 59,942,987 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	57,290,916 - 57,348,720 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	57,291,156 - 57,348,720 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	61,822,485 - 61,879,030 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	58,366,449 - 58,424,124 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	54,717,075 - 54,774,576 (+)	NCBI		Celera
RGSC_v3.1	5	58,366,721 - 58,408,789 (+)	NCBI
Cytogenetic Map	5	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-hydroxypropanoic acid (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amiodarone (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

casticin (ISO)

clofibrate (EXP)

cobalt dichloride (EXP)

coumarin (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

finasteride (EXP)

flutamide (EXP)

formaldehyde (ISO)

FR900359 (ISO)

fulvestrant (ISO)

gentamycin (EXP)

L-ethionine (EXP)

methimazole (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

nefazodone (EXP)

omeprazole (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

pentachlorophenol (ISO)

perfluorohexanesulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (EXP)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

rac-lactic acid (ISO)

rotenone (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

succimer (ISO)

sulfadimethoxine (EXP)

thioacetamide (EXP)

topotecan (EXP)

triphenyl phosphate (ISO)

troglitazone (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

negative regulation of MHC class II biosynthetic process (ISO)

negative regulation of transcription by RNA polymerase II (IBA,IEA,ISO)

protein autoubiquitination (ISO)

regulation of DNA-templated transcription (IEA)

Cellular Component

nucleolus (ISO)

nucleoplasm (ISO)

nucleus (IBA,IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

metal ion binding (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA,ISO)

transferase activity (IEA)

ubiquitin protein ligase activity (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7964459	PMID:10500182	PMID:12047746	PMID:12477932	PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Nfx1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	60,900,140 - 60,958,889 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	60,901,217 - 60,958,889 (+)	Ensembl				GRCr8
mRatBN7.2	5	56,104,945 - 56,162,912 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	56,105,234 - 56,162,912 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	58,071,542 - 58,129,118 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	59,890,692 - 59,948,268 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	59,885,062 - 59,942,987 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	57,290,916 - 57,348,720 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	57,291,156 - 57,348,720 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	61,822,485 - 61,879,030 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	58,366,449 - 58,424,124 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	54,717,075 - 54,774,576 (+)	NCBI		Celera
RGSC_v3.1	5	58,366,721 - 58,408,789 (+)	NCBI
Cytogenetic Map	5	q22	NCBI

NFX1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	33,290,516 - 33,371,157 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	33,290,428 - 33,371,872 (+)	Ensembl			hg38	GRCh38
GRCh37	9	33,290,514 - 33,371,155 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	33,280,510 - 33,361,155 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	33,280,509 - 33,338,719	NCBI
Celera	9	33,220,555 - 33,301,274 (+)	NCBI		Celera
Cytogenetic Map	9	p13.3	NCBI
HuRef	9	33,247,318 - 33,327,704 (+)	NCBI		HuRef
CHM1_1	9	33,290,194 - 33,370,948 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	33,309,149 - 33,389,758 (+)	NCBI		T2T-CHM13v2.0

Nfx1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	40,970,906 - 41,025,992 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	40,970,906 - 41,025,993 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	40,970,906 - 41,025,992 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	40,970,906 - 41,025,993 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	40,917,976 - 40,973,025 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	41,159,652 - 41,213,849 (+)	NCBI		MGSCv36	mm8
Celera	4	40,631,709 - 40,686,644 (+)	NCBI		Celera
Cytogenetic Map	4	A5	NCBI
cM Map	4	20.72	NCBI

Nfx1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	2,307,682 - 2,371,433 (-)	Ensembl
ChiLan1.0	NW_004955472	2,306,961 - 2,371,597 (-)	NCBI	ChiLan1.0	ChiLan1.0

NFX1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	91,232,589 - 91,315,646 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	91,238,531 - 91,321,602 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	33,068,235 - 33,149,271 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	33,876,836 - 33,959,924 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	33,876,836 - 33,959,924 (+)	Ensembl			panPan2	panpan1.1

NFX1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	50,387,368 - 50,462,978 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	50,387,883 - 50,462,428 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	49,017,302 - 49,092,686 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	51,327,657 - 51,403,266 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	51,328,098 - 51,404,681 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	49,991,742 - 50,067,296 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	49,859,107 - 49,935,686 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	50,624,061 - 50,699,626 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Nfx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	165,277,056 - 165,339,742 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	1,823,813 - 1,886,721 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	1,824,629 - 1,886,726 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NFX1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	33,126,607 - 33,200,680 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	10	33,126,460 - 33,200,819 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	37,446,410 - 37,473,033 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NFX1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	46,899,208 - 46,982,237 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	46,900,920 - 46,982,518 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	43,791,151 - 43,876,000 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nfx1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	38,044,117 - 38,127,512 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624736	38,054,231 - 38,124,497 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Nfx1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	117,166,828 - 117,210,894 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Nfx1
469 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	378
Count of miRNA genes:	213
Interacting mature miRNAs:	242
Transcripts:	ENSRNOT00000060691, ENSRNOT00000060692
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	32751649	77751649	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	38011670	83011670	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	52665372	94894052	Rat
6907115	Mcs29	Mammary carcinoma susceptibility QTL 29			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	38004331	83004331	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	23671493	79046465	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	17576633	62576633	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	38011670	83011670	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	38011670	83011670	Rat
1331782	Rf36	Renal function QTL 36	3.296		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	39019942	102105896	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	33311673	78311673	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	32751649	77751649	Rat
1641922	Alcrsp8	Alcohol response QTL 8			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	5	17486080	62486080	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	39985948	84985948	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	6922282	81330203	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33311673	78311673	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	39526924	84526924	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	48523123	91770353	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	91770353	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	60511627	105511627	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	7065535	74335773	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	17486080	62486080	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	87027358	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	26023211	71023211	Rat
2303577	Gluco47	Glucose level QTL 47	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	16520019	61520019	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	56546393	101546393	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	23671493	68671493	Rat

Markers in Region

D5Rat224

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	60,917,664 - 60,917,872 (+)	Marker Load Pipeline
RGSC_v3.4	5	58,382,896 - 58,383,103	RGD	RGSC3.4
RGSC_v3.4	5	58,382,897 - 58,383,104	UniSTS	RGSC3.4
Celera	5	54,733,466 - 54,733,663	UniSTS
RGSC_v3.1	5	58,383,075 - 58,383,282	RGD
SHRSP x BN Map	5	36.2599	RGD
SHRSP x BN Map	5	36.2599	UniSTS
Cytogenetic Map	5	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287600	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121205	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC098037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000060691 ⟹ ENSRNOP00000057422

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	60,901,217 - 60,942,232 (+)	Ensembl
mRatBN7.2 Ensembl	5	56,105,234 - 56,146,252 (+)	Ensembl
Rnor_6.0 Ensembl	5	57,291,301 - 57,332,697 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000060692 ⟹ ENSRNOP00000057423

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	60,901,217 - 60,958,889 (+)	Ensembl
mRatBN7.2 Ensembl	5	56,105,234 - 56,162,912 (+)	Ensembl
Rnor_6.0 Ensembl	5	57,291,156 - 57,348,720 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105959 ⟹ ENSRNOP00000096312

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	60,901,299 - 60,944,611 (+)	Ensembl
mRatBN7.2 Ensembl	5	56,109,875 - 56,148,630 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108374 ⟹ ENSRNOP00000093949

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	60,905,787 - 60,958,889 (+)	Ensembl
mRatBN7.2 Ensembl	5	56,109,804 - 56,162,912 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000157209 ⟹ ENSRNOP00000108823

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	60,901,217 - 60,955,839 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000160551 ⟹ ENSRNOP00000108253

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	60,901,217 - 60,955,839 (+)	Ensembl

RefSeq Acc Id:

NM_001024784 ⟹ NP_001019955

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	60,901,217 - 60,958,889 (+)	NCBI
mRatBN7.2	5	56,105,234 - 56,162,912 (+)	NCBI
Rnor_6.0	5	57,291,156 - 57,348,720 (+)	NCBI
Rnor_5.0	5	61,822,485 - 61,879,030 (+)	NCBI
RGSC_v3.4	5	58,366,449 - 58,424,124 (+)	RGD
Celera	5	54,717,075 - 54,774,576 (+)	RGD

Sequence:

show sequence

ACTGTATCTTCGGGCGGCACCACCCCCTTGGCCGTCTACACGCGCGTAGGAACGAATAGTCTCT
GGACGCCGGAAATCCGGGACACGTGACCAGGTGACAGCCCTCGCTCGGTGGCGGGGCTCGCTTG
AGGTGCTGCGGCACGGGATGGCGGAGGCGCCTCCGGTCTCAGGCACTTTTAAATTTAATACAGA
TGCTGCTGAGTTCATTCCGCAGGAGAGAAAAAATTCTGGTCTAAATTGTGGGACCCAAAGAAGA
CTAGATTCTAATAGGATTGGCAGAAGAAATTATAGTTCCTCACCTCCCTGCCACCTTCCTAGAC
ACATCCCTTACGATGATGTCTCTGCTGTTCACCAGCACGGTTATGCCTCCGGAAGCAAGCCTAA
GAGTCCACAGGGTTTTTTCCAGTCATCTAATAAATCACTCAAGAACCATGGGCTTCAGAATCAG
CCATGGCAGAAATTAAGGAATGAAAAGCACCAAAACAGAATCAAGAAAGCACAAGGGCTCACTG
AGCAGACGTCAGATACATCCAGTTTAGAAAGCGTAGCCAGATCCGAGAGTGGAACAAACCCTAG
AGAACACAGCCCTTCTGAGAGCGAGAAGGAGGTAGTTATTGCAGATCCCAGGGGAGCGAAACCC
AAAAAAGCCACGCAGCTTACATACAACTATGGCCGAGGGCCAAAGGCCAAAGGGAGACTCAGAA
GCGAGTGGGGTAACAGAATGAGCCCAAAGTCTGAGGATGAAAATGCCAGACCTGTGGCCATTTC
CCACTCTGACTCTTCAGAAGCCTCCTGTAGAAAACCTGTAGTGGATCCATGTGTGTGCAGACGG
AGTGAGCAGAGAAGATATCCCCAGAAAAGGCCTCCCTGGGAAGTAGAGGGGGCCAGACCACGGC
CAGGCAGGAACCCACCGAAACAGGAGAGTCAGCGGCATATAAATGCAGGGCCCAAAAACAACAT
GCCCCCCCTTCCAAAGGATAATCTCAGAGAGAGGCCAACGAAGTCAGCCTGTGACACTGGGAAT
TTGGCAGTTGTCACCAAGTCTTCCAGAAGAGTTGACCAAGAGAAAAATGCTGGAAGGAGACAGG
ATCCTCAAGTGCTGTCTCCTTTTCCCAGAGGCAAGCAGAACCATATGCTGAAGAATGTGGAAAC
TCATACAGGTTCCCTGATTGAGCAGCTAACTACAGAAAAGTACGAGTGTATGGTGTGCTGCGAG
TTGGTTCAGGTCACAGCCCCGGTGTGGAGCTGCCAGAGCTGTTTCCATGTCTTTCATCTGAACT
GCATCAAGAAATGGGCTCGCTCTCCAGCGTCCCACGCAGATGGCCAGAGTGGTTGGAGGTGCCC
CGCTTGTCAGAATGTTTCTGCACATGTTCCCAGTACCTACACTTGTTTCTGTGGCAAAGTAAAG
AACCCTGAATGGAGCAGAAATGAAATTCCGCACAGTTGTGGTGAAGTTTGTAGAAAGAAACAGC
CTGGCCAGGACTGTCCACATTCCTGTAATCTTCTCTGCCATCCTGGACCCTGCCCACCCTGCCC
TGCTTTTACAACTAAAACATGTGAATGTGGACGGACCAGGCACACGGTTCGCTGTGGTCAGCCT
GTCTCAGTCCACTGTTCTAATGTGTGTGAGAATATTTTGAACTGTGGTCAGCACCGCTGTGCTG
AGCTGTGCCATGCGGGTCAGTGCCAGCCTTGCCGGATCATATTGAACCAGGTGTGCTACTGTGG
CAGCACCTCCCGAGATGTGTTGTGTGGAACCGATGTGGGCAAGTCTGATGGATTTGGGGACTTC
AGCTGTTTAAAGATATGTGGCAAGGACTTGAAATGTGGGAGCCATACCTGTTCTCAGGTTTGCC
ACCCTCAGCCCTGTCAGCCTTGCCCAAGGCTCCCCCATTTGGTGCGATATTGCCCTTGCGGCCA
AACACCTCTCAGCCAGTTGCTGGAACATGGAAGTAATGGTCGGAAGACGTGCATGGATCCTGTT
CCTTCCTGTGGAAAAGTGTGTGGCAAACCCTTGTCCTGTGGGTCCTCAGATTTCATCCACACCT
GTGAAAAGCTCTGCCATGAGGGAGACTGTGGGCCGTGCTCGCGCACATCAGTCATTTCCTGCAG
ATGCTCCTTCAGAACAAAGGAGCTCCCGTGTACCAGTCTTAAAAGTGAAGATGCTACATTCATG
TGTGACAAGCGGTGTAACAAGAAACGATTGTGTGGACGGCATAAATGTAACGAGATCTGCTGTG
TGGACAAGGAGCACAAGTGTCCTTTGATTTGTGGGAGGAAACTCCGTTGTGGCCTTCATCGGTG
TGAAGAACCTTGTCACCGAGGGAACTGTCAGACCTGCTGGCAAGCCAGCTTTGATGAATTAACC
TGCCATTGTGGCGCCTCTGTGATCTACCCACCAGTTCCCTGTGGGACTAGGCCTCCTGAGTGTA
CCCAGACCTGTGCGAGGATCCATGAATGTGACCATCCAGTATATCATTCTTGTCATAGTGAGGA
GAAGTGTCCCCCTTGTACTTTCCTAACTCAGAAGTGGTGCATGGGCAAGCATGAGTTACGAAGC
AACATCCCCTGTCACCTGGTTGATATCTCTTGCGGATTACCCTGCAGTGCCATGCTACCCTGTG
GGATGCACAAATGTCAAAGACTCTGTCACAAAGGAGAATGTCTTGTGGATGAGGCCTGCAAGCA
GCCCTGTACCACACCCAGAGCTGACTGTGGCCACCCATGTATGGCTCCCTGCCACCCCAGTTTA
CCCTGCCCTGTGACAGCTTGTAAAGCCAAGGTAGAGTTACAGTGTGAATGTGGAAGAAGAAAGG
AGATGGTGATTTGCTCTGAAGCATCCGGGACTTATCAAAGGATAGCTGCCATTTCGATGGCCTC
TAAAATAACGGACATGCAGCTTGGAGACTCAGTGGAGATCAGCAAGTTCATTACCAAGAAGGAA
GTCCAACAAGCCAGGTTGCAGTGTGATGAGGAGTGTGCTGCCCTGGAAAGGAAAAAGAGATTGG
CAGAGGCATTCGACATCACTGATGACTCTGATCCTTTCAACGTACGCTCTTCAGCATCGAAATT
CAGTGACAGCCTGAAAGACGATGCCAGGAAAGACTTCAAGTTTGTCAGTGACATCGAGAAGGAA
ATGGAAGCGCTTGTGGAGGCCGTGAATAAGGGAAAGAGTAATAAGAAAAGCTACTGCTTCCCTC
CCATGAACAGAGACCACCGCCGCATCATCCATGACCTAGCCCAGGTTTATGGCCTGGAGAGTGT
GAGCTATGACAGTGAACCAAAGCGCAATGTCGTGGTCACTGCCATCAGAGGGAAGTCCATCTGT
CCTCCTACCACGCTGACCAGTGTTATTGAAAGGGAGACACAGACACGGCCTCCACCACCAATTC
CTCATCACCGACACCAAGCAGACAAGAATCCTGGGAGCAGTAATTTACAGAAGATCGTGAAGGA
GCCTGTGATTGACTACTTTGACGTCCAGGACTGAGAAGATAGATATATTTAGATAAAAGGATAA
TGCTGTGCACTGGAGACTCATTTGCCGGCAGATAAATCATGCCCGCTCCTCCTGCCTGGCATGG
CCGCAGCACCCGTGCTGTCTTGTTCCGATACAGCCAAGCATGAATGTGTCAGGACCCCAGTCTC
TCCAGCCCACAGGCCCCTGGCTCCGTGGCCACTGGATTTTTAGTCACGTTTTGAAGAGGCTGCT
CACACCATCACTGTGATTACTAAGAGATTGGGGGAGTATCAGATTTTATTTGGATAAACCAGAA
TTTTTATCCCAAACTGGCTTTGTGGCACTTGGTGTCCCACTTGTTCCCCCGTGGGCCTCACCTT
CCTCATGAGGAAAGACACACGAAGCCCTGACCGTCAGTAAGCTGTCTGGAACCATGTGTCTTAA
ACCTAGCCATCTTATCCAAAAGCTTCCGATGTCTCTCACGACTGGTCAGGTTGCTTGATAGAAT
TCCGTCTTCTCAAATCCCTGGCATTCTCTCACCATGTCACCAAGCCTACCCAGGAACAGTTTAG
CTGTCTGCCATAATGGTAAGACCTTGGGCAAGCTCTTCTGTCGTGTTCACAACTGTGGGTCTAT
GCACTGTCCACTGTAGCCCTAAGTTCTCTGTGGTTGATAGCAGCTCTCACATAGACAGCAGGAC
GGGGTAGCTTTTCCCTGGGCTTTCAGCAGCCACAGACTCTCCCTACATCTGAGCTCTGAACCAC
TGTTCCGATATTCAAAGAAGTGTGTGGACAGTCCAGGGCCTGTGCCAAGTGCCCTACTGTAGGC
CCTCAGCCTCCTTAAAGCAGGCGTGTGCCTTCTGTGTCGGCCCCCTCTGCACAAGCTGGACTCC
TCTCTTTGTTGTTTTTTCTTTTTCTTTCTTTTTTTTTTTTTTTGTTTTTTCTTTCTTTGTTTTT
GTTTTTTGTTTGTTTTGGTTTTGGCTTTTTTTCAAGACAGGGTTTTTCTGTGTAGCCCTGGCTG
TCCTGGAGCTCACTCCTGTAGATCCATCTGCCTCTGCCTTCTGAGTGCTGGGATTAAAGGCATG
TGCCACCACCGCCTAGCTTCTTTTTGCTTTAAAATAAACTTTGAGCCCCCAAAACTTGGAATCA
TTAAACAAGGTACTTAGTTTGTA

hide sequence

RefSeq Acc Id:

XM_008763623 ⟹ XP_008761845

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	60,900,140 - 60,943,310 (+)	NCBI
mRatBN7.2	5	56,104,965 - 56,148,633 (+)	NCBI
Rnor_6.0	5	57,290,916 - 57,334,506 (+)	NCBI

Sequence:

show sequence

TGTCGCCTGCGTGAGTCACTCCAAGCGGACTCTTATCTGAAGGACATTTGAAGCTGGGCGGATG
ACAGTACTTGATAAAAAGGCGTTGCAGCTGGAGAACCCAGCATCTCTCGAAAAACAATTACGCA
AGTTCGGTCACTAGATCCCGCGATCGGGAACACCCCTCCAGCCACACTCTCCCCGACCCCGGGC
TTCCGCCCTGGCCGGCGCATTTATCTGACGTCCCAAATGCGCCATTTCACTGTATCTTCGGGCG
GCACCACCCCCTTGGCCGTCTACACGCGCGTAGGAACGAATAGTCTCTGGACGCCGGAAATCCG
GGACACGTGACCAGGTGACAGCCCTCGCTCGGTGGCGGGGCTCGCTTGAGGTGCTGCGGCACGG
GATGGCGGAGGCGCCTCCGGTCTCAGGCACTTTTAAATTTAATACAGATGCTGCTGAGTTCATT
CCGCAGGAGAGAAAAAATTCTGGTCTAAATTGTGGGACCCAAAGAAGACTAGATTCTAATAGGA
TTGGCAGAAGAAATTATAGTTCCTCACCTCCCTGCCACCTTCCTAGACACATCCCTTACGATGA
TGTCTCTGCTGTTCACCAGCACGGTTATGCCTCCGGAAGCAAGCCTAAGAGTCCACAGGGTTTT
TTCCAGTCATCTAATAAATCACTCAAGAACCATGGGCTTCAGAATCAGCCATGGCAGAAATTAA
GGAATGAAAAGCACCAAAACAGAATCAAGAAAGCACAAGGGCTCACTGAGCAGACGTCAGATAC
ATCCAGTTTAGAAAGCGTAGCCAGATCCGAGAGTGGAACAAACCCTAGAGAACACAGCCCTTCT
GAGAGCGAGAAGGAGGTAGTTATTGCAGATCCCAGGGGAGCGAAACCCAAAAAAGCCACGCAGC
TTACATACAACTATGGCCGAGGGCCAAAGGCCAAAGGGAGACTCAGAAGCGAGTGGGGTAACAG
AATGAGCCCAAAGTCTGAGGATGAAAATGCCAGACCTGTGGCCATTTCCCACTCTGACTCTTCA
GAAGCCTCCTGTAGAAAACCTGTAGTGGATCCATGTGTGTGCAGACGGAGTGAGCAGAGAAGAT
ATCCCCAGAAAAGGCCTCCCTGGGAAGTAGAGGGGGCCAGACCACGGCCAGGCAGGAACCCACC
GAAACAGGAGAGTCAGCGGCATATAAATGCAGGGCCCAAAAACAACATGCCCCCCCTTCCAAAG
GATAATCTCAGAGAGAGGCCAACGAAGTCAGCCTGTGACACTGGGAATTTGGCAGTTGTCACCA
AGTCTTCCAGAAGAGTTGACCAAGAGAAAAATGCTGGAAGGAGACAGGATCCTCAAGTGCTGTC
TCCTTTTCCCAGAGGCAAGCAGAACCATATGCTGAAGAATGTGGAAACTCATACAGGTTCCCTG
ATTGAGCAGCTAACTACAGAAAAGTACGAGTGTATGGTGTGCTGCGAGTTGGTTCAGGTCACAG
CCCCGGTGTGGAGCTGCCAGAGCTGTTTCCATGTCTTTCATCTGAACTGCATCAAGAAATGGGC
TCGCTCTCCAGCGTCCCACGCAGATGGCCAGAGTGGTTGGAGGTGCCCCGCTTGTCAGAATGTT
TCTGCACATGTTCCCAGTACCTACACTTGTTTCTGTGGCAAAGTAAAGAACCCTGAATGGAGCA
GAAATGAAATTCCGCACAGTTGTGGTGAAGTTTGTAGAAAGAAACAGCCTGGCCAGGACTGTCC
ACATTCCTGTAATCTTCTCTGCCATCCTGGACCCTGCCCACCCTGCCCTGCTTTTACAACTAAA
ACATGTGAATGTGGACGGACCAGGCACACGGTTCGCTGTGGTCAGCCTGTCTCAGTCCACTGTT
CTAATGTGTGTGAGAATATTTTGAACTGTGGTCAGCACCGCTGTGCTGAGCTGTGCCATGCGGG
TCAGTGCCAGCCTTGCCGGATCATATTGAACCAGGTGTGCTACTGTGGCAGCACCTCCCGAGAT
GTGTTGTGTGGAACCGATGTGGGCAAGTCTGATGGATTTGGGGACTTCAGCTGTTTAAAGATAT
GTGGCAAGGACTTGAAATGTGGGAGCCATACCTGTTCTCAGGTTTGCCACCCTCAGCCCTGTCA
GCCTTGCCCAAGGCTCCCCCATTTGGTGCGATATTGCCCTTGCGGCCAAACACCTCTCAGCCAG
TTGCTGGAACATGGAAGTAATGGTCGGAAGACGTGCATGGATCCTGTTCCTTCCTGTGGAAAAG
TGTGTGGCAAACCCTTGTCCTGTGGGTCCTCAGATTTCATCCACACCTGTGAAAAGCTCTGCCA
TGAGGGAGACTGTGGGCCGTGCTCGCGCACATCAGTCATTTCCTGCAGATGCTCCTTCAGAACA
AAGGAGCTCCCGTGTACCAGTCTTAAAAGTGAAGATGCTACATTCATGTGTGACAAGCGGTGTA
ACAAGAAACGATTGTGTGGACGGCATAAATGTAACGAGATCTGCTGTGTGGACAAGGAGCACAA
GTGTCCTTTGATTTGTGGGAGGAAACTCCGTTGTGGCCTTCATCGGTGTGAAGAACCTTGTCAC
CGAGGGAACTGTCAGACCTGCTGGCAAGCCAGCTTTGATGAATTAACCTGCCATTGTGGCGCCT
CTGTGATCTACCCACCAGTTCCCTGTGGGACTAGGCCTCCTGAGTGTACCCAGACCTGTGCGAG
GATCCATGAATGTGACCATCCAGTATATCATTCTTGTCATAGTGAGGAGAAGTGTCCCCCTTGT
ACTTTCCTAACTCAGAAGTGGTGCATGGGCAAGCATGAGGAGCTCACAATTAAGAAACTTTGGA
CTTTTAAAGAGACTTTGGACTTTTGAAGTGTTGGAATTTTTGAAGACTTTGGGGGGCTTTTTTG
GAGTTGGACTATATTTTATATTAAGATTGTTACCATGAGATTTGGGGACAAGAAATGGAAAGTT
ATTGCACAAAGTGACATATTTGTTTGTTAAGTTGACATGAAATGAATTGTGCTGGTTTAACTGT
CAACTTAACACAACCTAGAATCACCCAGAAAGAGTCTTAGTGAGGAATTGCTTAGATCAGATTT
GGTTTATGGGTGTGTCTGTGGGGGATTGTCTTGATTGTTAATTGATGTGGGAAGACAAAGCCCA
CTGTGAGAGGCACCATTCCCTAGGCAGAAAATCCTAAACTGTGTGAACAAAAAAAATCAAGCTG
AGCAGCAAGCAAGCAACATGCATGTATTCATTTCTCTCTTCCCTTGACTGTGGACATGATAAGA
CTAGCTGCTGGAGTTCCTGCCTTGACCTAATGCAATAATGAGCTGTAACCTGGAATTGTAAGCC
AAATAAACCCTTTCCTCCTCTATGTTTCTTTTTGTCAGGCTATTTTATCACAGCAACAGAAATG
GCAAGGGTCCTGTGACTCATCTATATCCCTAGCCAATGAAAGAAAATTGTGTTGTATAACCAGG
GATATGTGATACTTGCTTCTCCTACTCCAAGATGACATATTTTCTAACCTGCTCTTGTTACTTC
ATAACATAATTCTTGATATCTGTAACATGTTTTCAATATTCTTTTATCTTTAGTAGACTTTCTT
TTCTGTACATATTTCCTATGGTAGTTTTGTTTGTTTTACTCTGTAGCCCTGGCTGGCCTCGAAC
TCACAGAAGCCACACTGCCCAGCCTCCTGCGATAGCTCTTAAGTCTCTATAAATTGTGTGTGTA
TGTGTGTGTGCATGCGCTTGCTTAGAGGCAGGATTTTATATTGGCCTCAAACTTGCCATGTAGC
CAAACATCTTGAATTCCTGTTTCTCTTGCCTCTGTGCCTCAGGTGCTGTGATTACAGGCATGTG
CCACCGTGTGCATATTGTGAATCTTACTTTCTCTGTTAGCTTATCTACCATAAAATACTCGTTT
ATTAGCTTTAGTCAATAAATAATAATCGAATATGTAATCTATGCCGGGTAACAGAGGAGGTGTG
GGGTGACTGAGAAGTTAACAAGACCGACACACCCCTGCCTATATGGATCAATCATTCAGGGATG
GACATGTAGTCAGAAACAGACAGTTGTGAGTAGAGTAATTTGAGGACTGCAGAGTCCTGGGGAG
ATAGTTCCTGCCAAAGAAAGGCATTCTAGAGGAAGAAGCTCATACAGGACACTAAGGTAGTACA
GTAAGCCAGGCATGAGTCATGCATGGGAAGCACAAGGTCTCCCTAAGTCCAAAGTGACTGGGAG
CATGTGTGTTCTACATCTGGAGGCCTCCAGTGTTAGAAGTCAGGAGTCATGGCAGCTGGACACA
CTAGCATGTGCTTGTAAATCTCAGCATTAGAAAGGCTGAGAGGCAGATTGAGAGTTGAGGCCAG
CCTAGGTGACCCATGACAAAATTAAAAAGTCAAAAATTATCTCCACATTCAAGGGCTTTTGAAG
GAATTTGAGGGAATCTATGAGAGTGACCCTGAAGCCGAGCTCAGTAGCTCACTCCTGTAATCCA
GCACTTGGGGAAGTGTGAGCAGGAGGATCAGTTCACAGCCAGCCTGTACTGCGAGACCCTGTTT
CCGAAAAGTAATCTTTGATCCCATAGTAATGAATTTCCAATGTATTTAACAGCCATGGGAGACC
TAGGAGCAGATAATTTCTCAAGAAATAAAATGAGTTGGGAGTT

hide sequence

RefSeq Acc Id:

XM_063287600 ⟹ XP_063143670

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	60,900,415 - 60,955,839 (+)	NCBI

RefSeq Acc Id:

XM_063287601 ⟹ XP_063143671

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	60,900,415 - 60,955,839 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001019955	(Get FASTA)	NCBI Sequence Viewer
	XP_008761845	(Get FASTA)	NCBI Sequence Viewer
	XP_063143670	(Get FASTA)	NCBI Sequence Viewer
	XP_063143671	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH98037	(Get FASTA)	NCBI Sequence Viewer
	EDL98652	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000057422.3
	ENSRNOP00000057423
	ENSRNOP00000057423.2
	ENSRNOP00000093949.1
	ENSRNOP00000096312
	ENSRNOP00000096312.2
	ENSRNOP00000108253
	ENSRNOP00000108253.1
	ENSRNOP00000108823.1

RefSeq Acc Id:

NP_001019955 ⟸ NM_001024784

- UniProtKB:

D4AE50 (UniProtKB/TrEMBL), A6IIT2 (UniProtKB/TrEMBL), A0A8I6AMR9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEAPPVSGTFKFNTDAAEFIPQERKNSGLNCGTQRRLDSNRIGRRNYSSSPPCHLPRHIPYDD
VSAVHQHGYASGSKPKSPQGFFQSSNKSLKNHGLQNQPWQKLRNEKHQNRIKKAQGLTEQTSDT
SSLESVARSESGTNPREHSPSESEKEVVIADPRGAKPKKATQLTYNYGRGPKAKGRLRSEWGNR
MSPKSEDENARPVAISHSDSSEASCRKPVVDPCVCRRSEQRRYPQKRPPWEVEGARPRPGRNPP
KQESQRHINAGPKNNMPPLPKDNLRERPTKSACDTGNLAVVTKSSRRVDQEKNAGRRQDPQVLS
PFPRGKQNHMLKNVETHTGSLIEQLTTEKYECMVCCELVQVTAPVWSCQSCFHVFHLNCIKKWA
RSPASHADGQSGWRCPACQNVSAHVPSTYTCFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCP
HSCNLLCHPGPCPPCPAFTTKTCECGRTRHTVRCGQPVSVHCSNVCENILNCGQHRCAELCHAG
QCQPCRIILNQVCYCGSTSRDVLCGTDVGKSDGFGDFSCLKICGKDLKCGSHTCSQVCHPQPCQ
PCPRLPHLVRYCPCGQTPLSQLLEHGSNGRKTCMDPVPSCGKVCGKPLSCGSSDFIHTCEKLCH
EGDCGPCSRTSVISCRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVDKEHK
CPLICGRKLRCGLHRCEEPCHRGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCAR
IHECDHPVYHSCHSEEKCPPCTFLTQKWCMGKHELRSNIPCHLVDISCGLPCSAMLPCGMHKCQ
RLCHKGECLVDEACKQPCTTPRADCGHPCMAPCHPSLPCPVTACKAKVELQCECGRRKEMVICS
EASGTYQRIAAISMASKITDMQLGDSVEISKFITKKEVQQARLQCDEECAALERKKRLAEAFDI
TDDSDPFNVRSSASKFSDSLKDDARKDFKFVSDIEKEMEALVEAVNKGKSNKKSYCFPPMNRDH
RRIIHDLAQVYGLESVSYDSEPKRNVVVTAIRGKSICPPTTLTSVIERETQTRPPPPIPHHRHQ
ADKNPGSSNLQKIVKEPVIDYFDVQD

hide sequence

RefSeq Acc Id:	XP_008761845 ⟸ XM_008763623
- Peptide Label:	isoform X3
- UniProtKB:	Q4V7B3 (UniProtKB/TrEMBL), A0A8I6ALJ0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEAPPVSGTFKFNTDAAEFIPQERKNSGLNCGTQRRLDSNRIGRRNYSSSPPCHLPRHIPYDD VSAVHQHGYASGSKPKSPQGFFQSSNKSLKNHGLQNQPWQKLRNEKHQNRIKKAQGLTEQTSDT SSLESVARSESGTNPREHSPSESEKEVVIADPRGAKPKKATQLTYNYGRGPKAKGRLRSEWGNR MSPKSEDENARPVAISHSDSSEASCRKPVVDPCVCRRSEQRRYPQKRPPWEVEGARPRPGRNPP KQESQRHINAGPKNNMPPLPKDNLRERPTKSACDTGNLAVVTKSSRRVDQEKNAGRRQDPQVLS PFPRGKQNHMLKNVETHTGSLIEQLTTEKYECMVCCELVQVTAPVWSCQSCFHVFHLNCIKKWA RSPASHADGQSGWRCPACQNVSAHVPSTYTCFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCP HSCNLLCHPGPCPPCPAFTTKTCECGRTRHTVRCGQPVSVHCSNVCENILNCGQHRCAELCHAG QCQPCRIILNQVCYCGSTSRDVLCGTDVGKSDGFGDFSCLKICGKDLKCGSHTCSQVCHPQPCQ PCPRLPHLVRYCPCGQTPLSQLLEHGSNGRKTCMDPVPSCGKVCGKPLSCGSSDFIHTCEKLCH EGDCGPCSRTSVISCRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVDKEHK CPLICGRKLRCGLHRCEEPCHRGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCAR IHECDHPVYHSCHSEEKCPPCTFLTQKWCMGKHEELTIKKLWTFKETLDF hide sequence

Ensembl Acc Id:

ENSRNOP00000057423 ⟸ ENSRNOT00000060692

Ensembl Acc Id:

ENSRNOP00000057422 ⟸ ENSRNOT00000060691

Ensembl Acc Id:

ENSRNOP00000093949 ⟸ ENSRNOT00000108374

Ensembl Acc Id:

ENSRNOP00000096312 ⟸ ENSRNOT00000105959

RefSeq Acc Id:	XP_063143670 ⟸ XM_063287600
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AMR9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063143671 ⟸ XM_063287601
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AMR9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000108253 ⟸ ENSRNOT00000160551

Ensembl Acc Id:

ENSRNOP00000108823 ⟸ ENSRNOT00000157209

Protein Domains

PHD-type R3H RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4AE50-F1-model_v2	AlphaFold	D4AE50	1-1114	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693640

Promoter ID:

EPDNEW_R4165

Type:

initiation region

Name:

Nfx1_1

Description:

nuclear transcription factor, X-box binding 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	57,291,255 - 57,291,315	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310277	AgrOrtholog
BioCyc Gene	G2FUF-41582	BioCyc
Ensembl Genes	ENSRNOG00000009015	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000060691.5	UniProtKB/TrEMBL
	ENSRNOT00000060692	ENTREZGENE
	ENSRNOT00000060692.6	UniProtKB/TrEMBL
	ENSRNOT00000105959	ENTREZGENE
	ENSRNOT00000105959.2	UniProtKB/TrEMBL
	ENSRNOT00000108374.2	UniProtKB/TrEMBL
	ENSRNOT00000157209.1	UniProtKB/TrEMBL
	ENSRNOT00000160551	ENTREZGENE
	ENSRNOT00000160551.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.1370.50	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7456610	IMAGE-MGC_LOAD
InterPro	NFX1_fam	UniProtKB/TrEMBL
	R3H_dom_sf	UniProtKB/TrEMBL
	R3H_NF-X1	UniProtKB/TrEMBL
	R3H_ss-bd	UniProtKB/TrEMBL
	Znf_NFX1	UniProtKB/TrEMBL
	Znf_PHD-finger	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
KEGG Report	rno:313166	UniProtKB/TrEMBL
MGC_CLONE	MGC:116193	IMAGE-MGC_LOAD
NCBI Gene	313166	ENTREZGENE
PANTHER	PTHR12360	UniProtKB/TrEMBL
	TRANSCRIPTIONAL REPRESSOR NF-X1	UniProtKB/TrEMBL
Pfam	R3H	UniProtKB/TrEMBL
	zf-NF-X1	UniProtKB/TrEMBL
PhenoGen	Nfx1	PhenoGen
PROSITE	R3H	UniProtKB/TrEMBL
	ZF_PHD_2	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000009015	RatGTEx
SMART	R3H	UniProtKB/TrEMBL
	ZnF_NFX	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
	SSF82708	UniProtKB/TrEMBL
UniProt	A0A8I6ALJ0	ENTREZGENE
	A0A8I6AMR9	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0M1C8_RAT	UniProtKB/TrEMBL
	A0ABK0M2K1_RAT	UniProtKB/TrEMBL
	A6IIT2	ENTREZGENE, UniProtKB/TrEMBL
	D4AE50	ENTREZGENE, UniProtKB/TrEMBL
	F7F8T5_RAT	UniProtKB/TrEMBL
	Q4V7B3	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A8I6ALJ0	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Nfx1	nuclear transcription factor, X-box binding 1	Nfx1_predicted	nuclear transcription factor, X-box binding 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Nfx1_predicted	nuclear transcription factor, X-box binding 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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