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Gene: E2f7 (E2F transcription factor 7) Rattus norvegicus

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Symbol:

E2f7

Name:

E2F transcription factor 7

RGD ID:

1310258

Description:

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; regulation of cell cycle process; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of cell population proliferation and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human E2F7 (E2F transcription factor 7); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

E2F-7; LOC314818; transcription factor E2F7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	E2F7 (E2F transcription factor 7)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	E2f7 (E2F transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	E2f7 (E2F transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	E2F7 (E2F transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	E2F7 (E2F transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	E2f7 (E2F transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	E2F7 (E2F transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	E2F7 (E2F transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	E2f7 (E2F transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	E2f7 (E2F transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	E2F7 (E2F transcription factor 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	E2F7 (E2F transcription factor 7)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	E2f7 (E2F transcription factor 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	E2f7 (E2F transcription factor 7)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	e2f7 (E2F transcription factor 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	e2f7 (E2F transcription factor 7)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	efl-3	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	efl-3	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ctnnd2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	e2f7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	e2f7	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	48,036,881 - 48,079,055 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	48,037,749 - 48,079,055 (+)	Ensembl				GRCr8
mRatBN7.2	7	46,150,533 - 46,192,739 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	46,151,293 - 46,192,734 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	48,049,531 - 48,091,687 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	50,252,659 - 50,294,815 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	50,030,385 - 50,072,539 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	53,275,659 - 53,318,261 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	53,275,676 - 53,316,481 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	53,286,853 - 53,328,709 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	49,689,755 - 49,751,823 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	42,963,883 - 43,003,790 (+)	NCBI		Celera
RGSC_v3.1	7	49,710,871 - 49,771,412 (+)	NCBI
Cytogenetic Map	7	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Disease Progression (ISO)

lung non-small cell carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2,4-diaminotoluene (ISO)

2-butoxyethanol (ISO)

2-palmitoylglycerol (ISO)

3-methylcholanthrene (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

antimycin A (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (EXP)

azathioprine (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bromobenzene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

cisplatin (ISO)

cobalt atom (ISO)

copper atom (ISO)

copper(0) (ISO)

coptisine (ISO)

coumestrol (ISO)

CU-O LINKAGE (ISO)

cyclosporin A (ISO)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

dioxygen (ISO)

doxorubicin (ISO)

endosulfan (ISO)

Enterolactone (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

gallic acid (ISO)

gentamycin (EXP)

harmine (ISO)

Lasiocarpine (ISO)

lead(0) (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

MeIQx (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (ISO)

nickel atom (ISO)

niclosamide (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phosphoramide mustard (EXP)

picoxystrobin (ISO)

propanal (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sotorasib (ISO)

succimer (ISO)

sunitinib (ISO)

temozolomide (ISO)

testosterone (EXP,ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trametinib (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

trovafloxacin (ISO)

tungsten (ISO)

Tungsten carbide (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chorionic trophoblast cell differentiation (IEA,ISO,ISS)

DNA damage response (IEA)

DNA damage response, signal transduction by p53 class mediator (IEA,ISO,ISS)

DNA-templated transcription (IEA)

hepatocyte differentiation (IEA,ISO,ISS)

negative regulation of cell population proliferation (ISO)

negative regulation of cytokinesis (IEA,ISO,ISS)

negative regulation of G1/S transition of mitotic cell cycle (IEA,ISO,ISS)

negative regulation of transcription by RNA polymerase II (IEA,ISO,ISS)

placenta development (IEA,ISO,ISS)

positive regulation of DNA endoreduplication (IEA,ISO,ISS)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of DNA-templated transcription (IEA,ISO)

regulation of transcription by RNA polymerase II (IBA,IEA)

sprouting angiogenesis (IEA,ISO,ISS)

trophoblast giant cell differentiation (IEA,ISO,ISS)

Cellular Component

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

RNA polymerase II transcription regulator complex (IBA)

transcription regulator complex (IEA)

Molecular Function

cis-regulatory region sequence-specific DNA binding (IEA,ISO)

DNA binding (IEA)

DNA-binding transcription factor activity (IEA,ISO,ISS)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

DNA-binding transcription repressor activity (IEA,ISO,ISS)

DNA-binding transcription repressor activity, RNA polymerase II-specific (IEA,ISO)

identical protein binding (IEA,ISO)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,IEA,ISO,ISS)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IEA,ISO)

sequence-specific double-stranded DNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12893818	PMID:15133492	PMID:18541936	PMID:22180533	PMID:22516201	PMID:22802528	PMID:22903062	PMID:23064266

Genomics

Comparative Map Data

E2f7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	48,036,881 - 48,079,055 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	48,037,749 - 48,079,055 (+)	Ensembl				GRCr8
mRatBN7.2	7	46,150,533 - 46,192,739 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	46,151,293 - 46,192,734 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	48,049,531 - 48,091,687 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	50,252,659 - 50,294,815 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	50,030,385 - 50,072,539 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	53,275,659 - 53,318,261 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	53,275,676 - 53,316,481 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	53,286,853 - 53,328,709 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	49,689,755 - 49,751,823 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	42,963,883 - 43,003,790 (+)	NCBI		Celera
RGSC_v3.1	7	49,710,871 - 49,771,412 (+)	NCBI
Cytogenetic Map	7	q22	NCBI

E2F7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	77,021,251 - 77,065,569 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	77,021,246 - 77,065,572 (-)	Ensembl			hg38	GRCh38
GRCh37	12	77,415,031 - 77,459,349 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	75,939,157 - 75,983,491 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	77,080,472 - 77,124,821 (-)	NCBI		Celera
Cytogenetic Map	12	q21.2	NCBI
HuRef	12	74,467,815 - 74,512,166 (-)	NCBI		HuRef
CHM1_1	12	77,380,867 - 77,425,221 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	76,999,082 - 77,043,421 (-)	NCBI		T2T-CHM13v2.0

E2f7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	110,580,799 - 110,623,245 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	110,581,300 - 110,623,245 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	110,745,439 - 110,787,384 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	110,745,439 - 110,787,384 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	110,182,521 - 110,224,440 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	110,149,578 - 110,191,483 (+)	NCBI		MGSCv36	mm8
MGSCv36	10	110,874,175 - 110,915,960 (+)	NCBI		MGSCv36	mm8
Celera	10	112,679,553 - 112,721,244 (+)	NCBI		Celera
Cytogenetic Map	10	D1	NCBI
cM Map	10	57.74	NCBI

E2f7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	16,148,480 - 16,186,282 (-)	Ensembl
ChiLan1.0	NW_004955405	16,148,640 - 16,187,272 (-)	NCBI	ChiLan1.0	ChiLan1.0

E2F7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	85,057,718 - 85,102,581 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	85,054,112 - 85,098,451 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	74,540,049 - 74,582,561 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	77,388,950 - 77,433,262 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	77,388,950 - 77,433,262 (-)	Ensembl			panPan2	panpan1.1

E2F7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	19,856,093 - 19,895,657 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	19,857,227 - 19,895,225 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	20,339,285 - 20,381,001 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	20,194,252 - 20,236,238 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	20,195,500 - 20,234,063 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	19,793,846 - 19,832,959 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	19,851,678 - 19,893,451 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	19,980,571 - 20,022,547 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

E2f7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	40,476,352 - 40,522,277 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936568	5,206,135 - 5,244,450 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936568	5,206,135 - 5,245,324 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

E2F7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	104,127,731 - 104,163,212 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	104,126,924 - 104,163,582 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	109,254,285 - 109,289,365 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

E2F7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	72,598,220 - 72,642,366 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	72,599,353 - 72,641,420 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	172,897,900 - 172,942,501 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

E2f7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624750	21,010,339 - 21,063,757 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624750	21,010,347 - 21,063,655 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

E2f7
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	188,884,201 - 188,926,337 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in E2f7
187 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	387
Count of miRNA genes:	209
Interacting mature miRNAs:	252
Transcripts:	ENSRNOT00000031986
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354644	Spl4	Serum phospholipid level QTL 4	4.9		blood phospholipid amount (VT:0006084)	blood phospholipid level (CMO:0001169)	7	21541977	51639954	Rat
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	23807606	68807606	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	45113903	90113903	Rat
1578652	Bmd15	Bone mineral density QTL 15	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	7	10517086	62346019	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	7216097	52216097	Rat
1549840	Bss5	Bone structure and strength QTL 5	9.8		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	26638057	71638057	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	24179478	86817926	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	31770293	110435881	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	10112916	60150541	Rat
631513	Scl7	Serum cholesterol level QTL 7	4.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	39845902	84845902	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	9460877	54460877	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
1354637	Scl30	Serum cholesterol level QTL 30	3.7		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	7	21541977	51639954	Rat
10755453	Coatc12	Coat color QTL 12		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	32998702	77998702	Rat
7411605	Foco14	Food consumption QTL 14	24.1	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	36178764	81178764	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	10112916	99900612	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
631534	Lnnr1	Liver neoplastic nodule remodeling QTL 1	3.85	0.001	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	7	36178764	81178764	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2303629	Vencon3	Ventilatory control QTL 3	7.25		respiration trait (VT:0001943)	respiration rate (CMO:0000289)	7	42996226	58678836	Rat
70190	Mcs6	Mammary carcinoma susceptibility QTL 6	2.29		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	28624575	65788017	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	21541977	86817926	Rat
1300138	Hrtrt9	Heart rate QTL 9	4.72		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	10498820	55498820	Rat
738033	Anxrr6	Anxiety related response QTL 6	4.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	7	17460447	62460447	Rat
70207	Niddm31	Non-insulin dependent diabetes mellitus QTL 31	3.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	20057232	65057232	Rat
61439	Cia8	Collagen induced arthritis QTL 8	5.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	7	27182914	72182914	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	65	165	86	85	54	80	54	6	331	178	11	144	75	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000031986 ⟹ ENSRNOP00000030798

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	46,151,293 - 46,192,734 (+)	Ensembl
Rnor_6.0 Ensembl	7	53,275,676 - 53,316,481 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094983 ⟹ ENSRNOP00000089197

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	46,151,293 - 46,158,768 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104778 ⟹ ENSRNOP00000081093

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	48,037,749 - 48,079,055 (+)	Ensembl
mRatBN7.2 Ensembl	7	46,151,293 - 46,192,729 (+)	Ensembl

RefSeq Acc Id:

NM_001108092 ⟹ NP_001101562

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	48,036,903 - 48,079,055 (+)	NCBI
mRatBN7.2	7	46,150,578 - 46,192,734 (+)	NCBI
Rnor_6.0	7	53,275,676 - 53,316,481 (+)	NCBI
Rnor_5.0	7	53,286,853 - 53,328,709 (+)	NCBI
RGSC_v3.4	7	49,689,755 - 49,751,823 (+)	RGD
Celera	7	42,963,883 - 43,003,790 (+)	RGD

Sequence:

show sequence

GGTGTTTTAGCGGGGACCGCGATCCCGGGCTGGAGCTTGTCTTAGGCGGGTAGGAAACGCTGTC
GCTACCACGGGTGGAGCGGAGGGTCTGCGAACTTTGCCCTGTCCTGCCCATGTCGCCAGTCGGC
CGCTGAGATCTACACGGTCTGCCGGCGCACGCGTGCGGCTGCGGGCGTCCCCGGAGATAGCCTC
CATCGCGCTGCGGCAGTAAGGAAGCGTGCGGCCCCCGGATGGGGAGGCGGGAATGCGGAGAAGG
GTTACCCGCCGCCCTGGCTGCCATCCCACAGGCCCCGGGTCCGAGTGCCCCTGCGGTTGTGCTG
GCTGCAGCGCTGGATGGAGGTAAATTGTTTAACACTAAAAGACTTGATCAGCCCCAGGCAGACC
AGACTAGATTTTGCCGTTGAAGATGCAGAGACCGCACAAAAGGAAAATATATTCGTCGATCGAT
CAAGGATGACCCCAAAGACGCCAATGAAAAATGAACCCATCGATCTGTCAAAGCAAAGAATCTT
TACTCCGGAAAGAAGTCCCATTACTCCGGTAAAGCTGGTGGACCGGCAGCCGCAGGTGGAACCG
TGGACACCCACGGCCAACCTGAAGATGCTCATCAGTGCGGCCAGCCCAGACATAAGGGACCGGG
AGAAGAAAAAGGAGCTGTTCAGACCCATTGAGAATAAGGGGGATGCATTTGTGAACTCCCTGCA
GCTTGATGTGGTTGGCGACAGTGCTGTGGATGACTACGAGAAGCGAAGGCCAAGCAGGAAACAG
AAGAGCTTGGGGCTGCTGTGCCAGAAGTTTCTAGCTCGCTATCCAAGCTACCCCTTGTCCACGG
AGAAAACCACCATCTCCCTGGATGAGGTCGCCGTCAGCCTTGGTGTGGAAAGGAGACGCATCTA
TGACATCGTAAATGTGCTGGAGTCTCTGCATCTGGTCAGCCGGGTAGCTAAGAATCAGTATGGT
TGGCATGGTCGGCACAGCCTTCCCAAAACCCTGCGGACCCTACAGAGACTGGGAGAGGAACAGA
AATACGAGGAGCAGATGGCCTGCCTCCAGCAGAAGGAGCTGGACCTGATGGAGTATAGGTTTGG
AGAACGCAGGAAAGATGGGTCTCCAGATCCCCGAGATCAACACCTACTCGATTTTTCTGAATCC
GACTACCCCTCTTCATCTGCAAACAGTCGAAAAGATAAATCTCTAAGAATTATGAGCCAGAAGT
TTGTCATGCTGTTCCTCGTCTCTAAAACCAAGATTGTTACCCTGGATGTAGCTGCCAAAATCCT
CATAGAAGAAAGCCAAGATACCCCGGACCACAGTAAATTCAAAACAAAGGTACGGAGGCTCTAT
GACATAGCCAATGTGCTGACCAGCTTGGCTCTGATAAAGAAAGTTCACGTGACAGAAGAGCGAG
GCCGCAAACCAGCCTTCAAATGGATCGGGCCCGTGGACTTCAGCTCCATTGATGAAGAACTCTT
GGACGTCTCTGCATCTGTCTTACCGGAACTGAAGAAGGAAACATATGGTCAGATTCGAGTGTGT
GCAAAAGAGAGGCTGGCGCGGTACGGTTCCTTTAACACGGTTCAGACATCTGAGAAGATACAGA
GAAAAGTGAACTCCGAGCCCAGCAGCCCACAGGGAGGAAAACAAGGGCCAGCCTATTCCCTGGA
AATTGGGAGTCTGGCCGCCATCTACAGACAGAAAGTAGAAGACAGTTCGCAGGGGGAAGCCTTT
GTCAATAAGAGAGCTGCACCTCCAGCAAGTGTCTTGGACCCTACCCTCCCTGTTGACTCCGAAT
ACTGTGTTAAGCCTTTAGCCCAGCCAGTATTTTCTGTCGCGCAAACAGAAAACCCTCAAATTCC
ACAGACCTCGCCTTTCCTGTGACCACGGGAAATGGGAGAGCTACACCCCTGGAAGATGCCTGTG
TCAAGGGTCAGCTCCCTGCTGCAGAAGACGCTTCCGGAAGGGCTGTCCCAAATGGCTTCATTGC
TTCTGAATGTGGAAACCCATCAAGAAATCCAGACACTGAAAAGTCTTCCAACGACAACGAGATC
ACCAAAGACCCCTCCCTGCTGCAGTATCTGTATGTTCAGTCTCCCGCAGGTTTAAATGGTTTTA
ACATGCTCTTACCGGGCGGTCAAACCCCCCATGCGGTGGCACCATCATCGGCTGCGATGCCGTC
CTTCGGTGTGCCTTGCATGTTCTTACCGTCTCCAGGATTGGGCCCCTTTCCAGTTCTCTATTCT
CCCGCAATACCCGGGCCCATCTCTTCAGCTCCCGGCACTCTCCCAAACACCGGACCCATGAACT
TCGGCTTGTCCACCCTGGCATCGGCCTCCCATCTTCTCATCAGTCCAGCAGCCATGGTCAATCC
AAAGTCATCCACCCTCCCTTCCGCAGATCCTCAGCTTCGGTGTCAGCCCCCACTAAACCCGAAT
CCAGTGATGCCAGGCTCACATGGTGTCATCCACCCGGAGTCCCCTGGTTACATGAGACATCCAG
TGTCCATGGTGAAGGCAGAACAGTCCCCTGCACCAGCGACTCCCAAGAGCATCCAACGGAGACA
TCGGGAGACGTTCTTCAAGACTCCTGGCAGCCTCGGTGATCCGGCCTTTAGAAGAGAAAGGAAC
CAATCCCGGAACACTAGCTCAGCCCAGAGGAGACTAGAAATCTCTAGCAGCGGGCCTGACTAAC
CTGAATCTTCAGTGGGTGGGGTGGCTTCAGTACCTGACATTCCCTGTGTCCCAGACAAATGTCC
TAAGTGGAACACGGGCCACCCCAGTCCTCAACTGGTGTCCTTGCTCTCACGCTCGAATCCACTG
GTTCTGCTAACTTCCCGATATCATGAGTCATCTGTTTTCCTGGAAGTAATTATTACTAATTATG
CATTTAATACCACCTAGCGTCCAGGCTGTGTGCGGTGTCACCGTGGTATTGCTCTGTGACTGCT
GTGGTTTTTCTGAAGGGGGAGTTGCCTAGCACTTAACCAGGGTAAGGTTTGGTGTCTAAGCCTT
TCCACCTGCCCTGAGCAAGTCTGTAGTGAGAACTGTCTCTGCAGCCTAAACGTGCTACCGCTTC
CTTAGGCTCCGGGAAGCCGTCTTCAGTGAGGAATCCTACGGTATTATTTATTCTGTCCCTGCAA
CGGGACTTTACTGCACAAAGTTTACAACATCATCCTAACATTTTCAGGGTATTGCGACTTGAAT
GTTTATACTTTTGTTGTTATTGTTGTTGTTATGATTTGCCCTGCACTTACTCTACAGCTTATTA
ATAATGTGGATAAATGTATATACGTGATAAATGTCAAGACCAAAATAACTGTGAATGCTACACC
TAGCCATTAATGAACTGTGCTGATGCATCTGGAGGTGTGGG

hide sequence

RefSeq Acc Id:

XM_006241321 ⟹ XP_006241383

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	48,036,881 - 48,079,055 (+)	NCBI
mRatBN7.2	7	46,150,533 - 46,192,739 (+)	NCBI
Rnor_6.0	7	53,275,659 - 53,318,261 (+)	NCBI
Rnor_5.0	7	53,286,853 - 53,328,709 (+)	NCBI

Sequence:

show sequence

CTCAAGGCGCCAGAGGAGGTGTTTTAGCGGGGACCGCGATCCCGGGCTGGAGCTTGTCTTAGGC
GGATGGAGGTAAATTGTTTAACACTAAAAGACTTGATCAGCCCCAGGCAGACCAGACTAGATTT
TGCCGTTGAAGATGCAGAGACCGCACAAAAGGAAAATATATTCGTCGATCGATCAAGGATGACC
CCAAAGACGCCAATGAAAAATGAACCCATCGATCTGTCAAAGCAAAGAATCTTTACTCCGGAAA
GAAGTCCCATTACTCCGGTAAAGCTGGTGGACCGGCAGCCGCAGGTGGAACCGTGGACACCCAC
GGCCAACCTGAAGATGCTCATCAGTGCGGCCAGCCCAGACATAAGGGACCGGGAGAAGAAAAAG
GAGCTGTTCAGACCCATTGAGAATAAGGGGGATGCATTTGTGAACTCCCTGCAGCTTGATGTGG
TTGGCGACAGTGCTGTGGATGACTACGAGAAGCGAAGGCCAAGCAGGAAACAGAAGAGCTTGGG
GCTGCTGTGCCAGAAGTTTCTAGCTCGCTATCCAAGCTACCCCTTGTCCACGGAGAAAACCACC
ATCTCCCTGGATGAGGTCGCCGTCAGCCTTGGTGTGGAAAGGAGACGCATCTATGACATCGTAA
ATGTGCTGGAGTCTCTGCATCTGGTCAGCCGGGTAGCTAAGAATCAGTATGGTTGGCATGGTCG
GCACAGCCTTCCCAAAACCCTGCGGACCCTACAGAGACTGGGAGAGGAACAGAAATACGAGGAG
CAGATGGCCTGCCTCCAGCAGAAGGAGCTGGACCTGATGGAGTATAGGTTTGGAGAACGCAGGA
AAGATGGGTCTCCAGATCCCCGAGATCAACACCTACTCGATTTTTCTGAATCCGACTACCCCTC
TTCATCTGCAAACAGTCGAAAAGATAAATCTCTAAGAATTATGAGCCAGAAGTTTGTCATGCTG
TTCCTCGTCTCTAAAACCAAGATTGTTACCCTGGATGTAGCTGCCAAAATCCTCATAGAAGAAA
GCCAAGATACCCCGGACCACAGTAAATTCAAAACAAAGGTACGGAGGCTCTATGACATAGCCAA
TGTGCTGACCAGCTTGGCTCTGATAAAGAAAGTTCACGTGACAGAAGAGCGAGGCCGCAAACCA
GCCTTCAAATGGATCGGGCCCGTGGACTTCAGCTCCATTGATGAAGAACTCTTGGACGTCTCTG
CATCTGTCTTACCGGAACTGAAGAAGGAAACATATGGTCAGATTCGAGTGTGTGCAAAAGAGAG
GCTGGCGCGGTACGGTTCCTTTAACACGGTTCAGACATCTGAGAAGATACAGAGAAAAGTGAAC
TCCGAGCCCAGCAGCCCACAGGGAGGAAAACAAGGGCCAGCCTATTCCCTGGAAATTGGGAGTC
TGGCCGCCATCTACAGACAGAAAGTAGAAGACAGTTCGCAGGGGGAAGCCTTTGTCAATAAGAG
AGCTGCACCTCCAGCAAGTGTCTTGGACCCTACCCTCCCTGTTGACTCCGAATACTGTGTTAAG
CCTTTAGCCCAGCCAGTATTTTCTGTCGCGCAAACAGATTTGCAGGCCTTCTCCGCACAGAATG
GTCTAAACGGACAAGTAGGTGTCCCCGTTCCTTCTGCAGCCTCGGATGCGGAGACCTTAAAGTC
AGCTCTGCTTGCCAGCCAGCCCCTGGTATACGTGCCCTCCACGTCACTCTTCATGCTATACGGG
AGTGTGCAGGAGGCACTGTCCCCAGAGTCAAGGTCAGAGGAGGATGGTAGTGGCTCCGATGTCC
CAGCTGACCTGTCCCTGGCACCCACTGCTCAGAAGCGCCTGTGTGAGGAGAGGAATCCTCTGGA
GGATGATGAGCCTGCTGTGAAAAGGCAAAGTCGGGAATTTGAAGACAGCCCCTTATCCCTAGTT
ATGCCCAAGAAACCCTCAAATTCCACAGACCTCGCCTTTCCTGTGACCACGGGAAATGGGAGAG
CTACACCCCTGGAAGATGCCTGTGTCAAGGGTCAGCTCCCTGCTGCAGAAGACGCTTCCGGAAG
GGCTGTCCCAAATGGCTTCATTGCTTCTGAATGTGGAAACCCATCAAGAAATCCAGACACTGAA
AAGTCTTCCAACGACAACGAGATCACCAAAGACCCCTCCCTGCTGCAGTATCTGTATGTTCAGT
CTCCCGCAGGTTTAAATGGTTTTAACATGCTCTTACCGGGCGGTCAAACCCCCCATGCGGTGGC
ACCATCATCGGCTGCGATGCCGTCCTTCGGTGTGCCTTGCATGTTCTTACCGTCTCCAGGATTG
GGCCCCTTTCCAGTTCTCTATTCTCCCGCAATACCCGGGCCCATCTCTTCAGCTCCCGGCACTC
TCCCAAACACCGGACCCATGAACTTCGGCTTGTCCACCCTGGCATCGGCCTCCCATCTTCTCAT
CAGTCCAGCAGCCATGGTCAATCCAAAGTCATCCACCCTCCCTTCCGCAGATCCTCAGCTTCGG
TGTCAGCCCCCACTAAACCCGAATCCAGTGATGCCAGGCTCACATGGTGTCATCCACCCGGAGT
CCCCTGGTTACATGAGACATCCAGTGTCCATGGTGAAGGCAGAACAGTCCCCTGCACCAGCGAC
TCCCAAGAGCATCCAACGGAGACATCGGGAGACGTTCTTCAAGACTCCTGGCAGCCTCGGTGAT
CCGGCCTTTAGAAGAGAAAGGAACCAATCCCGGAACACTAGCTCAGCCCAGAGGAGACTAGAAA
TCTCTAGCAGCGGGCCTGACTAACCTGAATCTTCAGTGGGTGGGGTGGCTTCAGTACCTGACAT
TCCCTGTGTCCCAGACAAATGTCCTAAGTGGAACACGGGCCACCCCAGTCCTCAACTGGTGTCC
TTGCTCTCACGCTCGAATCCACTGGTTCTGCTAACTTCCCGATATCATGAGTCATCTGTTTTCC
TGGAAGTAATTATTACTAATTATGCATTTAATACCACCTAGCGTCCAGGCTGTGTGCGGTGTCA
CCGTGGTATTGCTCTGTGACTGCTGTGGTTTTTCTGAAGGGGGAGTTGCCTAGCACTTAACCAG
GGTAAGGTTTGGTGTCTAAGCCTTTCCACCTGCCCTGAGCAAGTCTGTAGTGAGAACTGTCTCT
GCAGCCTAAACGTGCTACCGCTTCCTTAGGCTCCGGGAAGCCGTCTTCAGTGAGGAATCCTACG
GTATTATTTATTCTGTCCCTGCAACGGGACTTTACTGCACAAAGTTTACAACATCATCCTAACA
TTTTCAGGGTATTGCGACTTGAATGTTTATACTTTTGTTGTTATTGTTGTTGTTATGATTTGCC
CTGCACTTACTCTACAGCTTATTAATAATGTGGATAAATGTATATACGTGATAAATGTCAAGAC
CAAAATAACTGTGAATGCTACACCTAGCCATTAATGAACTGTGCTGATGCATCTGGAGGTGTGG
GAACGAAAACTGAAGTCTAGGTGCCTTGTGACTGTTCCTCCAGCAACGATGAACGAGGTCTTGC
CATTTGTTTAAAACAAAACAAATCCTCCTTGTGCTCATCTCCCTTCACTCTGCACCCGTGTATC
CTAATTTAAATGTTCTCTGTAGCGTGCCAGGGTGTGTGCCTTCTCACGGCTGCCGTTTATAAGA
CAAATCAGGACGACATTGCGGAACGGAGGCCGTGGGAACCTGGATAAGAGTTTTGGTTGAATTA
TGAAGCACAATGAGAGGGAGACAGAGCGATAGACAATTATCTTCTTTTTTCCTTTCCACATTTC
CCTGTGTCCAGAGGAGAACGGGCATTCTGTCCATTTCTAACAGTGTTCATTCATACATCCCGTG
GTCCTCCCAGAACCAGCACAGTGAGCACGGTGTTGGTTGTTCTAATAGTTGTTCTGCAAAGTGC
ACAAGGCCCTCTGTGAGCCGCATTGCTCTAGGGTTCCCCGTGTTCTACACTGAAGTTACCACAC
GCTTGTCTCTTCTACTTCCTTTTCTCCTCTATTTTAGTCTGTCTTCTATTTAAACTTCTTAGAC
TCTAGTCTTAATATAAGGCTATTTTTCCCCTTTGTATTTTTGTACCCTGTGAAATACTATATAA
AAGGATAAAAAATATTAATTTAAGAGACTCTGGGAGTCCGATCAGAGTAGCTTTATATTAACTA
CAGGATGCTTTTAGCCTCACTACACCCAACACTAGCTTTGGGAAACTTGAGATAGGTAAAGCCT
GTTTAACACATTCGCTACTTCATCAAATTCTTCATCAACACTAAGCTTATAAAGTTGAAAAAAA
AGGTATTGTTCCTTTTTTAAATTTTTTTTTCTTGAGTTAGGTAAAAATTGCATGCTGTCTATGA
CTCTGAAGCCACACTGCTGGTCCCTTGCTGGAACATGAAAGTGACCCCCTTTCCAGGAGTGTAT
CAGACGTGCAGCAAGTGAGTCTCCTATGCACTGCTTGCTTTTAAGATCCCTGGAGCATAGGGAC
TTCCACAAAGCATTTCCGTCAAGAAATGCACATCTCCCCATAGACACAGACCTGTCTTCTCTCG
TTCCTGGATAGCCTTCATTTATCTTTAACCTTTTGCTATCCCTTCTTATTATACTCAGTTACCC
TGTGAATTGACCATTATTAACCTCAGAGAATTTATGATTCTTGGGAGGCGTCAAGCAATTCCAC
CCATGGGAAACGAAAGTTAACTTCTGGATTAGGGTCCCACTCGCCGTGGCTTCTGACTCTGCCA
GAAGACCGGTCTCTGAAGCTTTATGGCTAGACCTGAGTGCCTGAGACAGAGAAGCAGTGGCTTC
TCATTTAGTGCAAGAAGAAATAAGGGAGGGCATGGGCTTTGAGTCAGCACTGAGGGGGCGTGCT
ACCTCAAACCGTGCCGTCCGGGGTTTCCAAAACCCTTGCATTCCGGTACAAGAGCTGGGGATAT
AACTTATACTTGAACCTACCTACGAAGTTTACATTGCTCGATGCAAGGTGCTATTTTTGGACTT
AAGCGGCTGTGATGTGAAGCTGCTTCCTGCTTCTCTTGTTGCACTGCTAGACTTACGTAGGTGT
TGACTTCATTGCTGCTTGTCGCTTCTTCGTTGTCATGGGGCTTGGGCTCTGCTCTTTCCTAGTG
GCTGTATTATCTATGGCCATCTACTTGTAACGCTACTACATGTAAACCAATCTTTCCTTTTAGA
AAAGTACTAAGCTTTATAAAGTAGCCATGGAAATAAATGTATTTAGTAAGGCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101562	(Get FASTA)	NCBI Sequence Viewer
	XP_006241383	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D4A4D7	(Get FASTA)	NCBI Sequence Viewer
	EDM16748	(Get FASTA)	NCBI Sequence Viewer
	EDM16749	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000081093
	ENSRNOP00000081093.1

RefSeq Acc Id:

NP_001101562 ⟸ NM_001108092

- UniProtKB:

D4A4D7 (UniProtKB/Swiss-Prot), A0A0A0MY02 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEVNCLTLKDLISPRQTRLDFAVEDAETAQKENIFVDRSRMTPKTPMKNEPIDLSKQRIFTPER
SPITPVKLVDRQPQVEPWTPTANLKMLISAASPDIRDREKKKELFRPIENKGDAFVNSLQLDVV
GDSAVDDYEKRRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVN
VLESLHLVSRVAKNQYGWHGRHSLPKTLRTLQRLGEEQKYEEQMACLQQKELDLMEYRFGERRK
DGSPDPRDQHLLDFSESDYPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEES
QDTPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSIDEELLDVSA
SVLPELKKETYGQIRVCAKERLARYGSFNTVQTSEKIQRKVNSEPSSPQGGKQGPAYSLEIGSL
AAIYRQKVEDSSQGEAFVNKRAAPPASVLDPTLPVDSEYCVKPLAQPVFSVAQTENPQIPQTSP
FL

hide sequence

RefSeq Acc Id:	XP_006241383 ⟸ XM_006241321
- Peptide Label:	isoform X1
- UniProtKB:	D4A4D7 (UniProtKB/Swiss-Prot), A0A0A0MY02 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEVNCLTLKDLISPRQTRLDFAVEDAETAQKENIFVDRSRMTPKTPMKNEPIDLSKQRIFTPER SPITPVKLVDRQPQVEPWTPTANLKMLISAASPDIRDREKKKELFRPIENKGDAFVNSLQLDVV GDSAVDDYEKRRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVN VLESLHLVSRVAKNQYGWHGRHSLPKTLRTLQRLGEEQKYEEQMACLQQKELDLMEYRFGERRK DGSPDPRDQHLLDFSESDYPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEES QDTPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSIDEELLDVSA SVLPELKKETYGQIRVCAKERLARYGSFNTVQTSEKIQRKVNSEPSSPQGGKQGPAYSLEIGSL AAIYRQKVEDSSQGEAFVNKRAAPPASVLDPTLPVDSEYCVKPLAQPVFSVAQTDLQAFSAQNG LNGQVGVPVPSAASDAETLKSALLASQPLVYVPSTSLFMLYGSVQEALSPESRSEEDGSGSDVP ADLSLAPTAQKRLCEERNPLEDDEPAVKRQSREFEDSPLSLVMPKKPSNSTDLAFPVTTGNGRA TPLEDACVKGQLPAAEDASGRAVPNGFIASECGNPSRNPDTEKSSNDNEITKDPSLLQYLYVQS PAGLNGFNMLLPGGQTPHAVAPSSAAMPSFGVPCMFLPSPGLGPFPVLYSPAIPGPISSAPGTL PNTGPMNFGLSTLASASHLLISPAAMVNPKSSTLPSADPQLRCQPPLNPNPVMPGSHGVIHPES PGYMRHPVSMVKAEQSPAPATPKSIQRRHRETFFKTPGSLGDPAFRRERNQSRNTSSAQRRLEI SSSGPD hide sequence

Ensembl Acc Id:

ENSRNOP00000030798 ⟸ ENSRNOT00000031986

Ensembl Acc Id:

ENSRNOP00000081093 ⟸ ENSRNOT00000104778

Ensembl Acc Id:

ENSRNOP00000089197 ⟸ ENSRNOT00000094983

Protein Domains

E2F/DP family winged-helix DNA-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A4D7-F1-model_v2	AlphaFold	D4A4D7	1-902	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695185

Promoter ID:

EPDNEW_R5710

Type:

initiation region

Name:

E2f7_1

Description:

E2F transcription factor 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	53,275,691 - 53,275,751	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310258	AgrOrtholog
BioCyc Gene	G2FUF-34144	BioCyc
Ensembl Genes	ENSRNOG00000026252	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000104778	ENTREZGENE
	ENSRNOT00000104778.1	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.10.10	UniProtKB/Swiss-Prot
InterPro	E2F	UniProtKB/Swiss-Prot
	E2F_WHTH_DNA-bd_dom	UniProtKB/Swiss-Prot
	WH-like_DNA-bd_sf	UniProtKB/Swiss-Prot
	WH_DNA-bd_sf	UniProtKB/Swiss-Prot
NCBI Gene	314818	ENTREZGENE
PANTHER	PTHR12081	UniProtKB/Swiss-Prot
	TRANSCRIPTION FACTOR E2F7	UniProtKB/Swiss-Prot
Pfam	E2F_TDP	UniProtKB/Swiss-Prot
PhenoGen	E2f7	PhenoGen
RatGTEx	ENSRNOG00000026252	RatGTEx
SMART	E2F_TDP	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46785	UniProtKB/Swiss-Prot
UniProt	A0A0A0MY02	ENTREZGENE
	A6IGF0_RAT	UniProtKB/TrEMBL
	D4A4D7	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	E2f7	E2F transcription factor 7	E2f7_predicted	E2F transcription factor 7 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	E2f7_predicted	E2F transcription factor 7 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD