Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tppp | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TPPP mRNA] | CTD | PMID:31150632 | Tppp | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TPPP mRNA | CTD | PMID:36331819 | Tppp | Rat | 1,1-dichloroethene | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of TPPP mRNA | CTD | PMID:26682919 | Tppp | Rat | 1,2-dichloroethane | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TPPP mRNA | CTD | PMID:28960355 | Tppp | Rat | 17beta-estradiol | multiple interactions | ISO | TPPP (Homo sapiens) | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of TPPP mRNA | CTD | PMID:20404318 | Tppp | Rat | 17beta-estradiol | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | Estradiol results in decreased expression of TPPP mRNA | CTD | PMID:39298647 | Tppp | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression more ... | CTD | PMID:25975270 | Tppp | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tppp (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TPPP mRNA | CTD | PMID:28922406 | Tppp | Rat | 2-palmitoylglycerol | increases expression | ISO | TPPP (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of TPPP mRNA | CTD | PMID:37199045 | Tppp | Rat | aflatoxin B1 | increases methylation | ISO | TPPP (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of TPPP intron; Aflatoxin B1 results in increased methylation more ... | CTD | PMID:30157460 | Tppp | Rat | benzo[a]pyrene | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of TPPP mRNA] | CTD | PMID:22228805 | Tppp | Rat | benzo[a]pyrene | increases methylation | ISO | TPPP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TPPP promoter | CTD | PMID:27901495 | Tppp | Rat | benzo[a]pyrene | affects methylation | ISO | TPPP (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TPPP 5' UTR | CTD | PMID:27901495 | Tppp | Rat | benzo[a]pyrene | increases expression | ISO | Tppp (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TPPP mRNA | CTD | PMID:22228805 | Tppp | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TPPP mRNA | CTD | PMID:28085963 | Tppp | Rat | bisphenol A | decreases expression | ISO | TPPP (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of TPPP mRNA | CTD | PMID:22576693 | Tppp | Rat | bisphenol A | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TPPP mRNA | CTD | PMID:37894381 | Tppp | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TPPP mRNA | CTD | PMID:25181051 | Tppp | Rat | bisphenol A | increases methylation | ISO | TPPP (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of TPPP gene | CTD | PMID:22576693 | Tppp | Rat | bisphenol F | increases expression | ISO | Tppp (Mus musculus) | 6480464 | bisphenol F results in increased expression of TPPP mRNA | CTD | PMID:38685157 | Tppp | Rat | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of TPPP protein | CTD | PMID:28903499 | Tppp | Rat | cadmium atom | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TPPP more ... | CTD | PMID:37325564 | Tppp | Rat | cadmium dichloride | decreases expression | ISO | TPPP (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TPPP mRNA | CTD | PMID:26472689 | Tppp | Rat | cadmium dichloride | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TPPP more ... | CTD | PMID:37325564 | Tppp | Rat | cadmium dichloride | increases expression | ISO | TPPP (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of TPPP mRNA | CTD | PMID:38568856 | Tppp | Rat | carbon nanotube | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of TPPP mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Tppp | Rat | copper(II) chloride | increases expression | ISO | Tppp (Mus musculus) | 6480464 | cupric chloride results in increased expression of TPPP protein | CTD | PMID:29617964 | Tppp | Rat | Dibutyl phosphate | affects expression | ISO | TPPP (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TPPP mRNA | CTD | PMID:37042841 | Tppp | Rat | dimethylarsinic acid | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Tppp | Rat | dioxygen | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TPPP mRNA | CTD | PMID:30529165 | Tppp | Rat | doxorubicin | decreases expression | ISO | TPPP (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TPPP mRNA | CTD | PMID:29803840 | Tppp | Rat | epoxiconazole | increases expression | ISO | Tppp (Mus musculus) | 6480464 | epoxiconazole results in increased expression of TPPP mRNA | CTD | PMID:35436446 | Tppp | Rat | ethanol | affects splicing | ISO | Tppp (Mus musculus) | 6480464 | Ethanol affects the splicing of TPPP mRNA | CTD | PMID:30319688 | Tppp | Rat | folic acid | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | Folic Acid results in decreased expression of TPPP mRNA | CTD | PMID:25629700 | Tppp | Rat | FR900359 | affects phosphorylation | ISO | TPPP (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TPPP protein | CTD | PMID:37730182 | Tppp | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TPPP mRNA | CTD | PMID:33387578 | Tppp | Rat | hydrogen cyanide | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | Hydrogen Cyanide results in decreased expression of TPPP mRNA | CTD | PMID:33914522 | Tppp | Rat | irinotecan | increases expression | ISO | TPPP (Homo sapiens) | 6480464 | Irinotecan analog results in increased expression of TPPP mRNA | CTD | PMID:18927307 | Tppp | Rat | lead(0) | affects expression | ISO | TPPP (Homo sapiens) | 6480464 | Lead affects the expression of TPPP mRNA | CTD | PMID:28903495 | Tppp | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of TPPP gene | CTD | PMID:35440735 | Tppp | Rat | methylarsonic acid | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Tppp | Rat | niclosamide | increases expression | ISO | TPPP (Homo sapiens) | 6480464 | Niclosamide results in increased expression of TPPP mRNA | CTD | PMID:36318118 | Tppp | Rat | okadaic acid | increases expression | ISO | TPPP (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of TPPP mRNA | CTD | PMID:38832940 | Tppp | Rat | ozone | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:27106289|PMID:34911549 | Tppp | Rat | ozone | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | Ozone results in decreased expression of TPPP mRNA | CTD | PMID:33026818 | Tppp | Rat | paracetamol | affects expression | ISO | Tppp (Mus musculus) | 6480464 | Acetaminophen affects the expression of TPPP mRNA | CTD | PMID:17562736 | Tppp | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TPPP mRNA | CTD | PMID:33387578 | Tppp | Rat | paracetamol | increases expression | ISO | TPPP (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TPPP mRNA | CTD | PMID:29067470 | Tppp | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of TPPP mRNA | CTD | PMID:32680482 | Tppp | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TPPP mRNA | CTD | PMID:36331819 | Tppp | Rat | phenformin | decreases expression | EXP | | 6480464 | Phenformin results in decreased expression of TPPP mRNA | CTD | PMID:31324951 | Tppp | Rat | phenobarbital | affects expression | ISO | Tppp (Mus musculus) | 6480464 | Phenobarbital affects the expression of TPPP mRNA | CTD | PMID:23091169 | Tppp | Rat | potassium cyanide | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | Potassium Cyanide results in decreased expression of TPPP mRNA | CTD | PMID:33914522 | Tppp | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of TPPP mRNA | CTD | PMID:28903501 | Tppp | Rat | progesterone | increases expression | ISO | Tppp (Mus musculus) | 6480464 | Progesterone results in increased expression of TPPP mRNA | CTD | PMID:22238285 | Tppp | Rat | resveratrol | multiple interactions | ISO | TPPP (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of TPPP mRNA | CTD | PMID:23557933 | Tppp | Rat | rotenone | decreases expression | ISO | TPPP (Homo sapiens) | 6480464 | Rotenone results in decreased expression of TPPP protein | CTD | PMID:39603559 | Tppp | Rat | sevoflurane | increases expression | ISO | Tppp (Mus musculus) | 6480464 | Sevoflurane results in increased expression of TPPP protein | CTD | PMID:35249202 | Tppp | Rat | sodium arsenate | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Tppp | Rat | sodium arsenite | multiple interactions | ISO | Tppp (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Tppp | Rat | sodium arsenite | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TPPP mRNA | CTD | PMID:37682722 | Tppp | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TPPP mRNA | CTD | PMID:31150632 | Tppp | Rat | tetrachloromethane | decreases expression | ISO | Tppp (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of TPPP mRNA | CTD | PMID:31919559 | Tppp | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TPPP mRNA] | CTD | PMID:31150632 | Tppp | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TPPP mRNA | CTD | PMID:34492290 | Tppp | Rat | titanium dioxide | increases methylation | ISO | Tppp (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of TPPP gene | CTD | PMID:35295148 | Tppp | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of TPPP mRNA | CTD | PMID:33387578 | Tppp | Rat | trichostatin A | affects expression | ISO | TPPP (Homo sapiens) | 6480464 | trichostatin A affects the expression of TPPP mRNA | CTD | PMID:28542535 | Tppp | Rat | triptonide | increases expression | ISO | Tppp (Mus musculus) | 6480464 | triptonide results in increased expression of TPPP mRNA | CTD | PMID:33045310 | Tppp | Rat | urethane | increases expression | ISO | TPPP (Homo sapiens) | 6480464 | Urethane results in increased expression of TPPP mRNA | CTD | PMID:28818685 | Tppp | Rat | valproic acid | affects expression | ISO | Tppp (Mus musculus) | 6480464 | Valproic Acid affects the expression of TPPP mRNA | CTD | PMID:17963808 | Tppp | Rat | valproic acid | increases methylation | ISO | TPPP (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TPPP gene | CTD | PMID:29154799 | Tppp | Rat | valproic acid | increases expression | ISO | TPPP (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TPPP mRNA | CTD | PMID:23179753|PMID:28001369 | Tppp | Rat | valproic acid | affects expression | ISO | TPPP (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TPPP mRNA | CTD | PMID:25979313 | | 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