Unc80 (unc-80 subunit of NALCN channel complex) - Rat Genome Database

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Gene: Unc80 (unc-80 subunit of NALCN channel complex) Rattus norvegicus
Analyze
Symbol: Unc80
Name: unc-80 subunit of NALCN channel complex (Ensembl:unc-80 homolog, NALCN channel complex subunit)
RGD ID: 1309976
Description: Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation homeostasis. Predicted to be located in plasma membrane. Predicted to be part of sodium channel complex. Predicted to be active in axon. Orthologous to human UNC80 (unc-80 homolog, NALCN channel complex subunit); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC316460; LOC689982; LOC689991; LOC689998; ribulose-5-phosphate-3-epimerase; Rpe; similar to CG18437-PA; unc-80 homolog; unc-80 homolog (C. elegans); unc-80 homolog, NALCN activator; unc-80 homolog, NALCN channel complex subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8975,461,618 - 75,639,849 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl975,461,599 - 75,639,842 (+)EnsemblGRCr8
mRatBN7.2968,011,940 - 68,190,135 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl968,011,728 - 68,187,659 (+)EnsemblmRatBN7.2
Rnor_6.0973,492,907 - 73,686,578 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl973,493,027 - 73,683,000 (+)Ensemblrn6Rnor6.0
Rnor_5.0973,616,239 - 73,807,462 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4965,289,560 - 65,465,731 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera965,492,937 - 65,670,906 (+)NCBICelera
Cytogenetic Map9q32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The pentose phosphate pathway in the endoplasmic reticulum. Bublitz C and Steavenson S, J Biol Chem. 1988 Sep 15;263(26):12849-53.
2. The interdependence of glycolytic and pentose cycle intermediates in ad libitum fed rats. Casazza JP and Veech RL, J Biol Chem. 1986 Jan 15;261(2):690-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. UNC80 mutation causes a syndrome of hypotonia, severe intellectual disability, dyskinesia and dysmorphism, similar to that caused by mutations in its interacting cation channel NALCN. Perez Y, etal., J Med Genet. 2016 Jun;53(6):397-402. doi: 10.1136/jmedgenet-2015-103352. Epub 2015 Nov 6.
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. A humble hexose monophosphate pathway metabolite regulates short- and long-term control of lipogenesis. Veech RL Proc Natl Acad Sci U S A. 2003 May 13;100(10):5578-80. Epub 2003 Apr 29.

Genomics

Comparative Map Data
Unc80
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8975,461,618 - 75,639,849 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl975,461,599 - 75,639,842 (+)EnsemblGRCr8
mRatBN7.2968,011,940 - 68,190,135 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl968,011,728 - 68,187,659 (+)EnsemblmRatBN7.2
Rnor_6.0973,492,907 - 73,686,578 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl973,493,027 - 73,683,000 (+)Ensemblrn6Rnor6.0
Rnor_5.0973,616,239 - 73,807,462 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4965,289,560 - 65,465,731 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera965,492,937 - 65,670,906 (+)NCBICelera
Cytogenetic Map9q32NCBI
UNC80
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382209,771,832 - 209,999,296 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2209,771,569 - 209,999,300 (+)Ensemblhg38GRCh38
GRCh372210,636,556 - 210,864,020 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362210,344,962 - 210,369,516 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342210,462,222 - 210,486,777NCBI
Celera2204,404,518 - 204,632,058 (+)NCBICelera
Cytogenetic Map2q34NCBI
HuRef2202,481,632 - 202,708,824 (+)NCBIHuRef
CHM1_12210,642,543 - 210,870,219 (+)NCBICHM1_1
T2T-CHM13v2.02210,251,971 - 210,480,010 (+)NCBIT2T-CHM13v2.0
Unc80
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39166,507,093 - 66,738,309 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl166,507,526 - 66,738,307 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38166,467,915 - 66,699,150 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl166,468,367 - 66,699,148 (+)Ensemblmm10GRCm38
MGSCv37166,515,021 - 66,745,722 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36166,438,140 - 66,633,074 (+)NCBIMGSCv36mm8
Celera166,990,322 - 67,213,375 (+)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.56NCBI
Unc80
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554575,442,502 - 5,649,086 (-)Ensembl
ChiLan1.0NW_0049554575,445,255 - 5,649,286 (-)NCBIChiLan1.0ChiLan1.0
UNC80
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213112,394,604 - 112,622,962 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B112,409,575 - 112,637,941 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B97,029,102 - 97,257,181 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B215,434,345 - 215,660,429 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B215,434,343 - 215,660,423 (+)EnsemblpanPan2panpan1.1
UNC80
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13717,648,432 - 17,864,915 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3717,649,104 - 17,861,277 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3718,529,606 - 18,745,484 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03717,584,471 - 17,802,797 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3717,583,976 - 17,799,721 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13717,539,925 - 17,751,895 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03717,502,709 - 17,717,984 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03717,517,081 - 17,732,444 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Unc80
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303166,141,759 - 166,330,568 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936845268,919 - 454,031 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936845268,357 - 454,557 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC80
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15112,491,523 - 112,714,876 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115112,463,832 - 112,717,510 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215124,213,160 - 124,437,606 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UNC80
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11095,462,153 - 95,700,498 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1095,462,834 - 95,700,514 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040103,654,570 - 103,884,461 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc80
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247656,226,240 - 6,443,142 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247656,223,853 - 6,443,564 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Unc80
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14140,170,953 - 140,352,994 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Unc80
603 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:77
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000032430
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat

Markers in Region
D9Got72  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2968,158,390 - 68,158,588 (+)MAPPERmRatBN7.2
Rnor_6.0973,654,833 - 73,655,030NCBIRnor6.0
Rnor_5.0973,647,576 - 73,647,773UniSTSRnor5.0
RGSC_v3.4965,437,310 - 65,437,508RGDRGSC3.4
RGSC_v3.4965,437,311 - 65,437,508UniSTSRGSC3.4
Celera965,639,162 - 65,639,359UniSTS
RGSC_v3.1965,584,293 - 65,584,490RGD
RH 3.4 Map9604.9UniSTS
RH 3.4 Map9604.9RGD
RH 2.0 Map9649.9RGD
Cytogenetic Map9q32UniSTS
RH138119  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2968,046,945 - 68,047,066 (-)MAPPERmRatBN7.2
mRatBN7.2968,046,945 - 68,047,066 (+)MAPPERmRatBN7.2
Rnor_6.0973,528,792 - 73,528,912NCBIRnor6.0
Rnor_6.0972,665,120 - 72,665,240NCBIRnor6.0
Rnor_5.0973,771,317 - 73,771,437UniSTSRnor5.0
Rnor_5.0974,623,476 - 74,623,596UniSTSRnor5.0
RGSC_v3.4965,325,019 - 65,325,139UniSTSRGSC3.4
Celera965,527,789 - 65,527,909UniSTS
RH 3.4 Map9596.0UniSTS
Cytogenetic Map9q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 6 44 155 71 67 40 30 40 6 214 99 5 138 55 91 27 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003754536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide FQ214579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000032430   ⟹   ENSRNOP00000035988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl975,461,599 - 75,639,842 (+)Ensembl
mRatBN7.2 Ensembl968,011,728 - 68,187,659 (+)Ensembl
Rnor_6.0 Ensembl973,529,612 - 73,683,000 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000074427   ⟹   ENSRNOP00000064149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl973,493,027 - 73,521,913 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084340   ⟹   ENSRNOP00000074546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl973,528,681 - 73,529,120 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089478   ⟹   ENSRNOP00000068926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl975,461,599 - 75,639,842 (+)Ensembl
mRatBN7.2 Ensembl968,011,728 - 68,187,659 (+)Ensembl
Rnor_6.0 Ensembl973,493,027 - 73,528,829 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000142637   ⟹   ENSRNOP00000104902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl975,461,599 - 75,639,842 (+)Ensembl
RefSeq Acc Id: XM_039084598   ⟹   XP_038940526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
mRatBN7.2968,011,940 - 68,190,135 (+)NCBI
RefSeq Acc Id: XM_039084599   ⟹   XP_038940527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
mRatBN7.2968,011,940 - 68,186,556 (+)NCBI
RefSeq Acc Id: XM_039084600   ⟹   XP_038940528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
mRatBN7.2968,011,940 - 68,186,556 (+)NCBI
RefSeq Acc Id: XM_039084601   ⟹   XP_038940529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
mRatBN7.2968,011,940 - 68,186,556 (+)NCBI
RefSeq Acc Id: XM_039084602   ⟹   XP_038940530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
mRatBN7.2968,011,940 - 68,186,556 (+)NCBI
RefSeq Acc Id: XM_063268130   ⟹   XP_063124200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268131   ⟹   XP_063124201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268132   ⟹   XP_063124202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268133   ⟹   XP_063124203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268134   ⟹   XP_063124204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268135   ⟹   XP_063124205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268136   ⟹   XP_063124206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268137   ⟹   XP_063124207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268138   ⟹   XP_063124208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268139   ⟹   XP_063124209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268140   ⟹   XP_063124210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
RefSeq Acc Id: XM_063268141   ⟹   XP_063124211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,461,618 - 75,639,849 (+)NCBI
Ensembl Acc Id: ENSRNOP00000068926   ⟸   ENSRNOT00000089478
Ensembl Acc Id: ENSRNOP00000035988   ⟸   ENSRNOT00000032430
Ensembl Acc Id: ENSRNOP00000064149   ⟸   ENSRNOT00000074427
Ensembl Acc Id: ENSRNOP00000074546   ⟸   ENSRNOT00000084340
RefSeq Acc Id: XP_038940526   ⟸   XM_039084598
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038940529   ⟸   XM_039084601
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038940527   ⟸   XM_039084599
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038940528   ⟸   XM_039084600
- Peptide Label: isoform X7
- UniProtKB: D3ZXX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940530   ⟸   XM_039084602
- Peptide Label: isoform X17
RefSeq Acc Id: XP_063124204   ⟸   XM_063268134
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063124205   ⟸   XM_063268135
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063124206   ⟸   XM_063268136
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063124200   ⟸   XM_063268130
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063124207   ⟸   XM_063268137
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063124203   ⟸   XM_063268133
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063124208   ⟸   XM_063268138
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063124201   ⟸   XM_063268131
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063124209   ⟸   XM_063268139
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063124210   ⟸   XM_063268140
- Peptide Label: isoform X15
- UniProtKB: A0A0G2JU17 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124202   ⟸   XM_063268132
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063124211   ⟸   XM_063268141
- Peptide Label: isoform X16
Ensembl Acc Id: ENSRNOP00000104902   ⟸   ENSRNOT00000142637
Protein Domains
Cation channel complex component UNC80 N-terminal   Protein UNC80 C-terminal   Protein UNC80 central region

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R470-F1-model_v2 AlphaFold M0R470 1-298 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309976 AgrOrtholog
BioCyc Gene G2FUF-27292 BioCyc
Ensembl Genes ENSRNOG00000028362 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032430 ENTREZGENE
  ENSRNOT00000032430.6 UniProtKB/TrEMBL
  ENSRNOT00000089478 ENTREZGENE
  ENSRNOT00000089478.3 UniProtKB/TrEMBL
  ENSRNOT00000142637 ENTREZGENE
  ENSRNOT00000142637.1 UniProtKB/TrEMBL
InterPro UNC80 UniProtKB/TrEMBL
  UNC80_C UniProtKB/TrEMBL
  UNC80_N UniProtKB/TrEMBL
NCBI Gene Unc80 ENTREZGENE
PANTHER PROTEIN UNC-80 HOMOLOG UniProtKB/TrEMBL
  UNC80 UniProtKB/TrEMBL
Pfam UNC80 UniProtKB/TrEMBL
  UNC80 UniProtKB/TrEMBL
  UNC80_C UniProtKB/TrEMBL
PhenoGen Unc80 PhenoGen
RatGTEx ENSRNOG00000028362 RatGTEx
UniProt A0A0G2JU17 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LTR3_RAT UniProtKB/TrEMBL
  D3ZXX3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Unc80  unc-80 subunit of NALCN channel complex  Unc80  unc-80 homolog, NALCN channel complex subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-06-12 Unc80  unc-80 homolog, NALCN channel complex subunit  Unc80  unc-80 homolog, NALCN activator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-25 Unc80  unc-80 homolog, NALCN activator  Unc80  unc-80 homolog (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-09 Unc80  unc-80 homolog (C. elegans)  LOC689991  similar to CG18437-PA  Data merged from RGD:1586310 737654 APPROVED
2015-07-29 LOC689991  similar to CG18437-PA  LOC689982  similar to CG18437-PA  Data merged from RGD:1586319 737654 PROVISIONAL
2015-07-29 LOC689991  similar to CG18437-PA  LOC689998  similar to CG18437-PA  Data merged from RGD:1586303 737654 PROVISIONAL
2010-11-19 Unc80  unc-80 homolog (C. elegans)  LOC316460  similar to CG18437-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-05 LOC316460  similar to CG18437-PA  Rpe_predicted  ribulose-5-phosphate-3-epimerase (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC689982  similar to CG18437-PA      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC689991  similar to CG18437-PA      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC689998  similar to CG18437-PA      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Rpe_predicted  ribulose-5-phosphate-3-epimerase (predicted)      Symbol and Name status set to approved 70820 APPROVED