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Gene: Polq (DNA polymerase theta) Rattus norvegicus

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Symbol:

Polq

Name:

DNA polymerase theta

RGD ID:

1309795

Description:

Predicted to enable several functions, including catalytic activity, acting on DNA; identical protein binding activity; and magnesium ion binding activity. Predicted to be involved in several processes, including DNA metabolic process; negative regulation of double-strand break repair via homologous recombination; and somatic hypermutation of immunoglobulin genes. Predicted to act upstream of or within DNA repair. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and nucleoplasm. Predicted to be active in mitochondrial nucleoid; nucleus; and site of double-strand break. Orthologous to human POLQ (DNA polymerase theta); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC288079; polymerase (DNA directed), theta; polymerase (DNA) theta

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	POLQ (DNA polymerase theta)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Treefam
Mus musculus (house mouse):	Polq (polymerase (DNA directed), theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Polq (DNA polymerase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	POLQ (DNA polymerase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	POLQ (DNA polymerase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Polq (DNA polymerase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	POLQ (DNA polymerase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	POLQ (DNA polymerase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Polq (DNA polymerase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Polq (DNA polymerase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	POLQ (DNA polymerase theta)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Polq (polymerase (DNA directed), theta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	polq (polymerase (DNA directed), theta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	polq-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	mus308	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	polq	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	polq	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	77,179,190 - 77,281,270 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	77,179,209 - 77,281,268 (-)	Ensembl				GRCr8
mRatBN7.2	11	63,673,796 - 63,775,905 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	63,673,816 - 63,775,878 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	72,486,222 - 72,588,279 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	65,148,446 - 65,250,504 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	64,183,460 - 64,286,292 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	66,585,860 - 66,695,369 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	66,585,881 - 66,695,353 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	69,680,992 - 69,786,646 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	65,474,661 - 65,577,382 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	63,151,051 - 63,249,442 (-)	NCBI		Celera
RGSC_v3.1	11	65,533,019 - 65,634,858 (-)	NCBI
Cytogenetic Map	11	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

hereditary breast ovarian cancer syndrome (ISO)

teratoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1-naphthyl isothiocyanate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

4-hydroxynon-2-enal (ISO)

acetamide (EXP)

aflatoxin B1 (EXP)

Aflatoxin B2 alpha (ISO)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

bromobenzene (EXP)

cadmium dichloride (ISO)

calcitriol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

cypermethrin (ISO)

DDT (EXP)

diclofenac (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

etoposide (ISO)

gentamycin (EXP)

glyphosate (EXP)

Lasiocarpine (ISO)

lead diacetate (EXP)

lead(0) (ISO)

lidocaine (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methoxychlor (EXP)

mitomycin C (ISO)

N(4)-hydroxycytidine (ISO)

N-ethyl-N-nitrosourea (ISO)

N-Nitrosopyrrolidine (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

perfluorooctanoic acid (ISO)

potassium dichromate (ISO)

quercetin (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

base-excision repair (IEA,ISO)

DNA damage response (IEA,ISO)

DNA repair (IEA,ISO)

DNA replication (IEA)

DNA-templated DNA replication (IEA)

double-strand break repair (IEA,ISO)

double-strand break repair via alternative nonhomologous end joining (IBA,IEA,ISO)

error-prone translesion synthesis (IEA,ISO)

negative regulation of double-strand break repair via homologous recombination (IEA,ISO)

protein homooligomerization (IEA,ISO)

replication fork processing (IEA,ISO)

RNA-templated DNA biosynthetic process (IEA)

somatic hypermutation of immunoglobulin genes (IEA,ISO)

Cellular Component

chromosome (IEA)

mitochondrial nucleoid (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

site of DNA damage (IEA,ISO)

site of double-strand break (IEA,ISO)

Molecular Function

5'-deoxyribose-5-phosphate lyase activity (IEA,ISO)

ATP binding (IEA)

catalytic activity (IEA)

chromatin binding (IEA,ISO)

DNA binding (IEA)

DNA helicase activity (IEA,ISO)

DNA-directed DNA polymerase activity (IBA,IEA,ISO)

helicase activity (IEA)

hydrolase activity (IEA)

identical protein binding (ISO)

magnesium ion binding (IEA,ISO)

nucleic acid binding (IEA)

nucleotide binding (IEA)

nucleotidyltransferase activity (IEA)

protein binding (ISO)

RNA-directed DNA polymerase activity (IEA)

single-stranded DNA helicase activity (IEA,ISO)

transferase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12663541	PMID:14576298	PMID:15542845	PMID:16172387	PMID:16222339	PMID:16890500	PMID:19188258	PMID:22135286	PMID:25642960	PMID:25642963	PMID:25643323	PMID:26636256

Genomics

Comparative Map Data

Polq
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	77,179,190 - 77,281,270 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	77,179,209 - 77,281,268 (-)	Ensembl				GRCr8
mRatBN7.2	11	63,673,796 - 63,775,905 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	63,673,816 - 63,775,878 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	72,486,222 - 72,588,279 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	65,148,446 - 65,250,504 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	64,183,460 - 64,286,292 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	66,585,860 - 66,695,369 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	66,585,881 - 66,695,353 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	69,680,992 - 69,786,646 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	65,474,661 - 65,577,382 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	63,151,051 - 63,249,442 (-)	NCBI		Celera
RGSC_v3.1	11	65,533,019 - 65,634,858 (-)	NCBI
Cytogenetic Map	11	q21	NCBI

POLQ
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	121,431,431 - 121,545,988 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	121,431,426 - 121,546,002 (-)	Ensembl			hg38	GRCh38
GRCh37	3	121,150,278 - 121,264,835 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	122,632,963 - 122,747,543 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	122,632,970 - 122,747,543	NCBI
Celera	3	119,560,070 - 119,674,301 (-)	NCBI		Celera
Cytogenetic Map	3	q13.33	NCBI
HuRef	3	118,524,685 - 118,638,983 (-)	NCBI		HuRef
CHM1_1	3	121,113,983 - 121,228,541 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	124,151,355 - 124,265,920 (-)	NCBI		T2T-CHM13v2.0

Polq
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	36,832,104 - 36,922,321 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	36,832,148 - 36,915,779 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	37,011,741 - 37,095,419 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	37,011,786 - 37,095,417 (+)	Ensembl			mm10	GRCm38
MGSCv37	16	37,011,872 - 37,095,503 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	36,931,025 - 37,014,636 (+)	NCBI		MGSCv36	mm8
Celera	16	37,420,971 - 37,504,641 (+)	NCBI		Celera
Cytogenetic Map	16	B3	NCBI
cM Map	16	26.32	NCBI

Polq
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955427	20,778,952 - 20,894,989 (-)	Ensembl
ChiLan1.0	NW_004955427	20,779,332 - 20,895,094 (-)	NCBI	ChiLan1.0	ChiLan1.0

POLQ
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	119,390,769 - 119,503,189 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	119,393,209 - 119,507,966 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	118,535,968 - 118,648,275 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	125,446,829 - 125,558,642 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	125,446,829 - 125,559,283 (-)	Ensembl			panPan2	panpan1.1

POLQ
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	24,713,174 - 24,837,113 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	24,714,086 - 24,837,402 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	24,740,603 - 24,864,403 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	24,955,417 - 25,079,364 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	24,955,413 - 25,079,355 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	24,753,758 - 24,877,644 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	24,789,905 - 24,920,067 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	25,352,722 - 25,476,912 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Polq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	129,517,678 - 129,617,872 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936536	7,904,981 - 8,004,199 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936536	7,904,166 - 8,004,305 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POLQ
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	138,978,609 - 139,108,500 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	138,962,634 - 139,108,499 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

POLQ
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	59,336,506 - 59,448,609 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	59,336,842 - 59,448,604 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	106,844,576 - 106,989,077 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Polq
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	26,649,727 - 26,807,222 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624731	26,649,606 - 26,808,098 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Polq
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	21,870,521 - 21,981,074 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Polq
1318 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	109
Count of miRNA genes:	92
Interacting mature miRNAs:	98
Transcripts:	ENSRNOT00000063995
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	46443168	91443168	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	73308487	96070872	Rat
1598811	Bp291	Blood pressure QTL 291	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	33306008	78306008	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	58928336	99753367	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	32943067	89836615	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	36428416	81428416	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	73850894	99753367	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	34618760	79618760	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	58931822	92356038	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	57754837	96071021	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	20193549	96351019	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	67962184	99753367	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	73308315	99753367	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	51071021	96071021	Rat
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	22524746	82951192	Rat
1598841	Memor7	Memory QTL 7			exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	11	33306008	78306008	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	54415391	96071021	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	36749459	81749459	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	36749459	81749459	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	68599321	96497754	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	69855943	99753367	Rat

Markers in Region

RH137198

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	3	9,492,778 - 9,493,079	NCBI	Rnor5.0
RGSC_v3.4	3	4,859,269 - 4,859,569	UniSTS	RGSC3.4
Celera	11	63,200,736 - 63,200,942	UniSTS
Celera	3	4,325,822 - 4,326,122	UniSTS
Cytogenetic Map	11	q22	UniSTS
Cytogenetic Map	18	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	67	161	88	87	56	84	56	6	336	183	11	140	73	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105878	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248391	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008768716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270379	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270380	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270381	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000063995 ⟹ ENSRNOP00000061230

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	77,179,209 - 77,281,268 (-)	Ensembl
mRatBN7.2 Ensembl	11	63,673,816 - 63,775,878 (-)	Ensembl
Rnor_6.0 Ensembl	11	66,585,881 - 66,695,353 (-)	Ensembl

RefSeq Acc Id:

NM_001105878 ⟹ NP_001099348

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	77,179,209 - 77,281,268 (-)	NCBI
mRatBN7.2	11	63,673,816 - 63,775,878 (-)	NCBI
Rnor_6.0	11	66,585,881 - 66,695,353 (-)	NCBI
Rnor_5.0	11	69,680,992 - 69,786,646 (-)	NCBI
RGSC_v3.4	11	65,474,661 - 65,577,382 (-)	RGD
Celera	11	63,151,051 - 63,249,442 (-)	RGD

Sequence:

show sequence

GAAGCAGAGGCGGGAAGATGGTGGCGGTAGCTGTCACTAGGCTGGGGTTCTGTCGCACGGGAGG
CCTCTGGGACTGTGTCGTGTCCTGAACAGTTAAGAGGAACTTGTTTGCAATGAGTCTTCCGCGC
CGGAGTGGGAAACGGCGGCGTTCATCATCCGGCTCCGACTCATTCTCGTTCTCGGGAGACGGTG
ATAGCTGTGTCAGCCCTCAGCTCCTGTGTAGGCCGGTGCTGAGTCCACCTCCGGGGCTGGGACG
CGGCCGGAGGCTCGCAGGGACAGGAACATGCAAGCAAAGAGTTTCTGATGACCAGATAGACCAG
CTGCTATTGGCAAACTGGGGACTCCCTAAAGCAGTTCTGGAGAAATACCACAATTTTGGTGTAA
AAAAGATGTTCGAATGGCAGGCAGAGTGTCTTTTGCTCGGACAAGTCCTGGAAGGAAAGAATCT
GGTTTATTCAGCTCCTACAAGTGCTGGGAAGACGCTTGTTGCAGAGTTACTTATTTTGAAGCGG
GTTTTGGAAACGCGGAAGAAAGCGTTGTTCATTCTGCCCTTTGTGTCTGTGGCTAAAGAGAAGA
AATACTATCTCCAGAGTCTGTTTCAGGAAGTAGGAATAAAGGTAGATGGCTATATGGGCAGCAC
CTCACCAACTGGACGTTTCTCCTCCTTGGACGTTGCTGTTTGCACTATTGAGAGAGCCAATGGG
CTGATCAATCGCCTCATTGAGGAAAATAAGATGGATCTCTTAGGAACGGTGGTCGTGGATGAGC
TACACATGCTGGGGGACTCTCACCGAGGGTATCTGCTGGAACTCTTACTGACCAAGGTTTGCTT
TGTCACTCGGAAGTCAGCATCGTGCCAGGCAGATTCGGCCAGTGCTCTGGCTTGTGCTGTGCAG
ATTGTTGGCATGAGTGCTACTCTTCCTAACCTGCAGCTCGTGGCTTCCTGGCTGAATGCTGAAC
TTTACCATACTGACTTTCGCCCTGTTCCACTTTTGGAATCAATAAAAGTAGGAAATTCCATATA
TGACTCTTCAATGAAGCTTGTGAGAGAATTTCAACCCCTGCTCCAAGTGAAGGGAGATGAAGAC
CACATTGTTAGTTTATGCTATGAGACGGTTCGGGATAACCATTCAGTATTAGTCTTTTGTCCAT
CAAAAAAATGGTGTGAGAAGGTGGCCGATATCATTGCCCGGGAGTTTTATAATCTGCACCATCA
ACCCGAGGGATTAGTAAAGTCATCTGAATTTCCACCAGTGATTCTAGACCAAAAGAGCCTTCTT
GAAGTGATAGATCAGTTAAAACGCTCACCTTCAGGACTAGACTCGGTGCTGAAGAATACTGTGC
CATGGGGAGTAGCGTTTCATCATGCAGGTCTTACTTTTGAAGAGAGGGATATCATCGAAGGAGC
CTTCCGTCAAGGTCTTATTCGCGTTTTGGCAGCAACGTCTACTCTTTCTTCTGGAGTGAACCTT
CCTGCACGTCGGGTGATTATTCGCACTCCGGTTTTCGGTGGTCAGCCTTTAGATATCCTCACTT
ATAAGCAGATGGTTGGTCGTGCTGGCAGGAAAGGAGTAGACACAATGGGTGAAAGTATACTAGT
TTGTAAGAACTCTGAGAAATCCAAGGGCATTGCTCTGCTTCAAGGTTCGCTGGAGCCTGTGCAC
AGCTGTCTGCAAAGCCAGGGAGAAGTCACTTCTACCATGATACGAGCTATTCTGGAGATAATCG
TCAGTGGGGTGGCAAGTACGTCACAAGATATGCAGACTTATGCTGCCTGCACATTCTTGGCTGC
TGACGTAAAGGAAGGGAAGCAAGGGATTCAGAGGAACCGAGATGATGTTCAGCGTGGGGCAGTC
GATGCCTGTGTGACGTGGCTGTTAGAAAACGAGTTCATCCAGGCGGCAGAGCCCAGTGACGGCA
CAGGAGGAAAGGTGTATCACCCAACACACCTTGGATCAGCTACTCTTTCTTCCTCACTTTCTCC
AACTGATACCCTGGATATTTTTGCTGACCTCCAAAGAGCAATGAAAGGCTTTGTTTTAGAGAAT
GACCTTCATATCGTCTACCTGGTTACACCTGTGTTTGAAGATTGGACTAGTATTGATTGGTATC
GGTTTTTCTGTTTATGGGAAAAATTACCAACTTCTATGAAAAGGGTGGCAGAGCTGGTTGGAGT
GGAGGAAGGGTTCTTGGCTCGATGTGTGAAAGGAAAAGTAGTAGCCAGAACTGAGAGACAGCAT
CGACAAATGGCCATCCATAAAAGGTTTTTCACAAGCCTTGTGTTATTGGATTTAATCAGTGAAA
TTCCCTTAAAGGAAATTAACCAGAAATATGGATGTAATCGTGGGCAGATTCAGTCTTTGCAACA
GTCAGCTGCTGTCTATGCAGGAATGATTACGGTGTTTTCCAACCGTCTGGGCTGGCACAACATG
GAGCTACTGCTTTCTCAGTTTCAGAAGCGTCTTACGTTTGGCATCCAGAGAGAGCTGTGTGACC
TGATCCGGGTATCCTCGCTCAACGCTCAGAGAGCCAGGTTCCTGTATGCCTCTGGCTTTCTCAC
CGTGGCGGACCTCGCCAGAGCTGACACTGTAGAGGTGGAGGCGGCTCTGAAGGACGCTCTGCCT
TTCAAAAGTGCCCGGAAGGCAGTGGACGAAGAAGAGGAAGCAGCTGAAGAACGCCGGAGTATGC
GCACTATTTGGGTGGCTGGCAAGAGCTTATCTGCAAGGGAAGCAGCAGCTTTAATAGTAGAAGA
AGCCAAAGTGATTCTGCAGCAGGACTTAATTGAAATGGGAGTACAGTGGGGTCCACACTCACCC
TTGAGTTCTAGCACACACTCACTGACCAGTGGGTCAGAAGTAAAGGAGCACACGTTCAAGTCCC
AGACTAAGAGTTCTCATAAAAGGTTAGCATCAAAGAGCAGGAACAGCATGAGAGTGAGTGGTTC
TAATGGTAAGCAGTCACCAGAGGCAGGGCAAGGCCTAGACGAGTGCAGAGAGCGCCCAGACTCT
CTCTGTAAGTTCCAGGGGAATCACGAGATCCAGACACCCTCCGTTTATAGGGCAAGAAAACGGA
CTTCTTTAGGTGTAAACAAAGAAATGCTTCGAACCTCTCTGAAGGAAGGAAAACCAAGCACTAA
GGAAGTTCTTCAAACTCTCTCATTTGAGAAAACAAGAAAAGCTGCTTTGAGTTTTAGTTCAGAG
CAGGCGAACAACAGTTTTCCATCTGGGAGAGACAGAAAGTATCGGAAAAAATCTTGGGGTAGCA
GTCCCATGAGTGACTCTGTGATGCATAGAGATGATTTACAAGGACAGACTATGTGTAAATCTAC
TCTATGTGAAGACCCACAGAAGTCCTTAGAGGAGCAGAATACAGAATACAGAAGTCCAGGGCTA
TTTGCAAAAAATGTATCTTTTTGTGCCAAAGAAAAATGCAACAAAACCTCATTCCCCTTACAAA
TGCAGCAGCCTTGCTTAAGGAGAAAACCAGAAAGTGGTGCTGCCGTGGACCATTCCGTTGCGGT
GTCTCAGAATAAAAATGTGGTGGAGCAACCCCCTGGTGCTCCTAGGGACAGAAGAGGATTGGCT
GCTCATGGCAGAGCAGAGGTAAATGAGGTGCTCACAGAGAATGGTACAGAAAGCCAACTCCACG
ACACTCATCCTGTCAGCCAGTGCCTGGAAAACCACAGTGAGAAGCAGACAAACACGTGCACCAG
ACAGAAGACATTGACAGAGGGGCAAGCTGGTATTAGTCATGTGACTAGAGGCTCAAATGATCTC
ACACCCATCAGATGTGAACGTTTAAAGCTTAACAGCAAAGAACATGACTCAAATCCTTGTCCTC
AAGCATTGGGAACTAACGCAGGCAGAACTGAGGCACCTCAGTCATCTGAAGCACTTGGTCAAGC
AGGAGGCCAGTGTGAAAATCTTCTAAATTCTCCTGGTATACAAGAAAAAACAAGTGCTCATGCA
ACAAATAAAACTGAACATAGTCATGTTGCTAACCAAGCCTTCTGTGACTTTGGAGATAGCTTAT
ACTTAGACACTCAGTCAGAGGAAATAATTGAACAGATGGCAACTAAAAATGCCACGCAAGGAGC
AGAAGCAGCAGGGATAACGGAGGAGGGCTCCGCCACTCAGAACGAGCCTCACAGCACTACAGGT
GGCCAGCATATCCCAGGAGCAGCCAACACAGACCATGTGGACCGTAAGAACACAGAGTCTGTGA
AAGAAAACCCCGAAAAGAACATCGACAGAAGAACTCCACACAGCCTCATTTTCCATTCTCCAAC
ACCTCAGGGGGGAAACAGTGCTTGCTTTAAAGAGAATGAGCATTCTGTTACTGATTCCCAGTTA
AACAGTTTTCTTCAAGGGTTGGAAACACAGGACAAGCCAATCATACCTCTGGCTCCTCAAATGA
GAACTTCTACTGGTGTAGAGGAAGAAAGTCTGCCTGAAACCAGTTTGAATATGAGTGACAGTAT
ACTATTTGACAGTTTTGGAGAAGATAGCTTTGGACAAAGACAGTCACTTGATGTAAAGGCAAAA
CAGCCCCTCCTTTCCGAAATGACACCAAACCATTTCCACAATCCTCCATACCCACAAGAAGACC
CAGTTATGACACCACATATGAGCGAGCCTCAGGGTACTCTGGAGCGAATGGCTTGTCTCAGTGG
TGAATCTATTATATTTTCAGAGATAGACTCTGCTCAGGTGATCGAAGCCTTAGACAATATGGCT
GCATTTTACATGCAAGAAAACTGTAACCCAATAACTCTTAAAACAGAACCCAGAGATTTGGCAG
CGCTGGGTAATGAGTGTCCCCAAGGAGAAGTGGTCAGAGGAGAACAACATGAAGGGTCCTCAAA
GCCCAAATTCATGGAGATAAATCAAGATAATTCATTCACTTGGTCAGCAGCATCATTTAACTTA
AGTCCAGAGCTGCAAAGGATTTTAGATAAAGTGTCTACTCCTCGAGAAAATGAAGAGCCCGAAT
TGATGCATGCAGACTTGTCTTGCTTTGAAGAAAACAGCACAGAGTCACATGAGAGACAGGACAT
GAATTCAGACTTGGGGACAGTTCAGAGAACTTCATTTCTCCCCAGTAATGGAGTTAAAAGCAGG
ACTGAAGGGCTAGAGAGCAAAGCCAAGCATGGTGGAGCCTCATCTGCCTTGCCTCATAAAGCTG
CAGCTGATGACAACGGCCTCATTCCTCCTACACCCCTTCCTGCCTCTGCCTCTGCCTCTGCCTC
TAAGCTAGCACTTCCAGAGATTCTCGGAACATCTGTAAAACATCAGAAAGCCAGTTGTTTATTT
GACTCACCTTCAGATAATCAAAACCAGGATTTAAGTCAAGAGCTTAGAGACAGCCTCAAGGACT
CTGATGGTTCTGTTGTAGACACAAGTTTTTTTCTGCAGTCTCAGGATGGACTGCTGTTAACTCA
AGCCTCATGCAGCTCAGAGAGCCTGGCCATAATTGACGTAGCGAGTGACCAGATTCTCTTTCAG
ACATTTGTGAAGGAGTGGCAGTGCCAAAAGCGCTTTTCCATCTCTCTAGCTTGTGAAAAGATGA
CAAGTTCGACGTCTTCCAAAACTGCTACCATAGGTGGAAGGTTGAAGCAAGTTAACTCACCACA
GGAAGCCTCTGTTGAAGATGATGGGTTCCCTGTGCATGGCTCTGACTGTGCTGTGGTAGTTGGA
CTAGCAGTGTGCTGGGGTGGAAAGGATGCCTATTATTTGTCATTGCAGAAGGAACAAAAGCAGT
CTGAAATGAGTCCTAGTTTGGCCCCACCACCTCTGGATGCAACACTAACTGTTAAGGAGAGGAT
GGAGTACCTTCAGTCCTGCTTGCAAAAGAAGTCTGACCAAGAACGGTCTGTTGTCACCTATGAT
TTCATCCAGACCTATAAAGTTCTCCTCTTGTCCTGTGGCATCTCACTGGAACCCAGCTATGAAG
ACCCCAAGGTGGCTTGCTGGCTTCTTGACCCGGATTCTAAGGAGCCAACTCTTCATAGCATAGT
GACCAGTTTTCTCCCCCATGAGCTAGCACTCCTAGAAGGAATAGAGACAGGCCCAGGAATTCAG
AGCCTGGGGCTAAATGTGAACACAGACCATTCTGGGCGGTACAGAGCGAGTGTGGAGTCTGTTC
TCATCTTCAACTCCATGAATCAACTCAACTCTATGTTGCAGAAGGAAAACCTTCACGATATTTT
CTGCAAAGTGGAGATGCCCTCTCAGTACTGCCTGGCCTTGCTGGAACTAAATGGAATTGGCTTT
AGTACTGCTGAGTGTGAAACTCAGAAGCATATCATGCAAGCCAAGCTGGACGCCATTGAGACTC
AAGCCTATCAACTCGCTGGCCACAGCTTCTCCTTTACAAGTGCAGATGACATCGCACAGGTTTT
ATTTTTGGAACTAAAGCTACCACCGAATGGAGAGATGAAAACACAAGGCGGCAGAAAGACTCTG
GGTTCCACCAGAAGAGGGACGGAGAGCGACCGCAAACTCAGGCTGGGAAGACGGTTCAGCACTA
GTAAGGATATTTTAAATAAGTTAAAGGACTTGCATCCTTTACCAGGCCTGATACTGGAATGGAG
AAGAATCAGTAATGCTATTACCAAAGTGGTCTTCCCCTTGCAGCGGGAAAAGCACCTGAACCCC
TTTCTCAGAATGGAGAGGATCTATCCTGTATCACAGTCACACACGGCTACAGGACGGATAACCT
TTACAGAACCCAATATCCAAAATGTGCCAAGAGATTTTGAGATTAAAATGCCAACACTAGTAAG
AGAGAGCCCACCTTCTCAAGCTTCAGGCAAGGGCCAGCTCGCGATGGCCAGACAAAATCAGAAG
GTTTATGGCCTGCACCCGGGGCAAAGAACGGTGCTGGAGAAGACCTCAGATAGAGGCGTGCCAT
TTTCAGTGAGCATGCGCCATGCCTTTGTGCCTTTCCCAGGTGGTTTGATATTGGCTGCCGACTA
CTCTCAGCTCGAACTGAGGATCCTGGCACACTTATCTCGTGACTGTCGTCTCATTCAAGTTTTA
AACTCAGGAGCGGATGTGTTCAGGAGCATTGCCGCTGAGTGGAAGATGATTGAGCCCGATGCTG
TTGGTGACAATCTGAGGCAACAGGCAAAGCAGATTTGCTATGGAATTATATATGGGATGGGAGC
TAAATCGTTAGGAGAGCAGATGGGCATTAAAGAAAATGATGCTGCTTGCTATATCGACTCTTTC
AAGTCCAGGTATAAAGGGATTAATCATTTCATGAGGGACACAGTGAAGAACTGTAGAAGAGATG
GATTTGTTGAGACAATTTTGGGAAGACGTAGATATTTGCCAGGAATCAAAGACAATAATCCTTA
TCATAAGGCACACGCTGAGCGTCAGGCCATCAACACAACAGTTCAAGGCTCAGCTGCTGACATA
GTCAAAGTAGCCACAGTTAACATCCAGAAGCAGCTAGAGACCTTCCATCCAACCTTCAAATCCC
ATGGTCATCGGGAAAGCATGCTCCAGAGTGACCGAGCAGGATTGTTGCCAAAGAGAAAAGTTAA
AGGGATGTTTTGTCCTATGAGAGGAGGATTCTTCATCCTTCAACTTCACGACGAGCTTTTATAT
GAAGTGGCAGAAGAGGATGTTGTTCAGGTAGCTCAGATTGTCAAGAATGAAATGGAATGTGCTA
TTAAACTTTCTGTGAAGCTGAAAGTGAAAGTGAAAATAGGTGCCAGCTGGGGGGAGCTGAAGGA
CTTTGATGTGTGATGGTGCAGTGCCCAGGTCCCAGGGCAGCCTGGGACACAGTCACTCAGAAAG
CAGAGTCTGCCCTTTCGCCTGCTCTCAAGTACGATGCACTTAAACGAGCAGGTCTCTAGCGGGC
TTTAATGTCTACCTCTTCTGGTCCCTGTGGTGTTACAAGGCTTTGAGGGGAGATTTATTCGTTA
TCCTCACTCTCAAAGAGCATCTATGAATTTGTCTTTCATAATTTATTGGAGCGTTAAACAGTCT
CAGAATGTATGCTTGAAAAATGCACTTAGCACTTTGGGTCCTCAACTGTGTAGATTGTGAAGGA
GTGGAGCTGCTGCCTCAGGGCCATTTTTATTCCTGTCAAGGACTCCGGCACTCATGATGTAATC
CCTCAAGAGCCTCGGGCAGTGCTCAGTCTCAGTCATTAGAGCTATGCAGTATGTGTGGCCTTTT
CCTACAGTAAAGCTTCTGAAGTCGAATTTTAAAATCTCAAATTGAAATTCTATAAGATAGTTAA
TATGTGTGGAAGGAATCTAGAAATGAGTTTTCATGAACTGTTGCTGCTTGTTCTTTTCCTCACC
GTTCCGACAAGGAAGGATTGGAATGCTCTTAAAATGAACTGTCTGTCAGCTTAGACATTGAGAC
ACTTGAATCTAACACTGCCAGGCCAGAAAAATGCCCTTTTGCGAGCCCCTTAGTGCCTCCATCC
GTATTTGTGGTATGGAGAGAATTCTCAGGCTCAAAACATTGAATTTCTTTACTCATAACTAATA
TCCTTTTGCTGTTCA

hide sequence

RefSeq Acc Id:

XM_039088124 ⟹ XP_038944052

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	77,179,190 - 77,278,166 (-)	NCBI
mRatBN7.2	11	63,673,796 - 63,772,776 (-)	NCBI

RefSeq Acc Id:

XM_039088125 ⟹ XP_038944053

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	77,197,841 - 77,281,270 (-)	NCBI
mRatBN7.2	11	63,692,446 - 63,775,905 (-)	NCBI

RefSeq Acc Id:

XM_039088126 ⟹ XP_038944054

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	77,179,190 - 77,225,740 (-)	NCBI
mRatBN7.2	11	63,673,796 - 63,720,880 (-)	NCBI

RefSeq Acc Id:

XM_063270379 ⟹ XP_063126449

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	77,179,190 - 77,281,270 (-)	NCBI

RefSeq Acc Id:

XM_063270380 ⟹ XP_063126450

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	77,184,249 - 77,281,270 (-)	NCBI

RefSeq Acc Id:

XM_063270381 ⟹ XP_063126451

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	77,179,190 - 77,223,323 (-)	NCBI

RefSeq Acc Id:

XR_005491001

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	77,179,190 - 77,281,270 (-)	NCBI
mRatBN7.2	11	63,673,796 - 63,775,905 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099348	(Get FASTA)	NCBI Sequence Viewer
	XP_038944052	(Get FASTA)	NCBI Sequence Viewer
	XP_038944053	(Get FASTA)	NCBI Sequence Viewer
	XP_038944054	(Get FASTA)	NCBI Sequence Viewer
	XP_063126449	(Get FASTA)	NCBI Sequence Viewer
	XP_063126450	(Get FASTA)	NCBI Sequence Viewer
	XP_063126451	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM11249	(Get FASTA)	NCBI Sequence Viewer
	EDM11250	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000061230
	ENSRNOP00000061230.1

RefSeq Acc Id:

NP_001099348 ⟸ NM_001105878

- UniProtKB:

D4A628 (UniProtKB/TrEMBL), A6IR96 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSLPRRSGKRRRSSSGSDSFSFSGDGDSCVSPQLLCRPVLSPPPGLGRGRRLAGTGTCKQRVSD
DQIDQLLLANWGLPKAVLEKYHNFGVKKMFEWQAECLLLGQVLEGKNLVYSAPTSAGKTLVAEL
LILKRVLETRKKALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPTGRFSSLDVAVCTI
ERANGLINRLIEENKMDLLGTVVVDELHMLGDSHRGYLLELLLTKVCFVTRKSASCQADSASAL
ACAVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLESIKVGNSIYDSSMKLVREFQPLLQV
KGDEDHIVSLCYETVRDNHSVLVFCPSKKWCEKVADIIAREFYNLHHQPEGLVKSSEFPPVILD
QKSLLEVIDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLS
SGVNLPARRVIIRTPVFGGQPLDILTYKQMVGRAGRKGVDTMGESILVCKNSEKSKGIALLQGS
LEPVHSCLQSQGEVTSTMIRAILEIIVSGVASTSQDMQTYAACTFLAADVKEGKQGIQRNRDDV
QRGAVDACVTWLLENEFIQAAEPSDGTGGKVYHPTHLGSATLSSSLSPTDTLDIFADLQRAMKG
FVLENDLHIVYLVTPVFEDWTSIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVAR
TERQHRQMAIHKRFFTSLVLLDLISEIPLKEINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRL
GWHNMELLLSQFQKRLTFGIQRELCDLIRVSSLNAQRARFLYASGFLTVADLARADTVEVEAAL
KDALPFKSARKAVDEEEEAAEERRSMRTIWVAGKSLSAREAAALIVEEAKVILQQDLIEMGVQW
GPHSPLSSSTHSLTSGSEVKEHTFKSQTKSSHKRLASKSRNSMRVSGSNGKQSPEAGQGLDECR
ERPDSLCKFQGNHEIQTPSVYRARKRTSLGVNKEMLRTSLKEGKPSTKEVLQTLSFEKTRKAAL
SFSSEQANNSFPSGRDRKYRKKSWGSSPMSDSVMHRDDLQGQTMCKSTLCEDPQKSLEEQNTEY
RSPGLFAKNVSFCAKEKCNKTSFPLQMQQPCLRRKPESGAAVDHSVAVSQNKNVVEQPPGAPRD
RRGLAAHGRAEVNEVLTENGTESQLHDTHPVSQCLENHSEKQTNTCTRQKTLTEGQAGISHVTR
GSNDLTPIRCERLKLNSKEHDSNPCPQALGTNAGRTEAPQSSEALGQAGGQCENLLNSPGIQEK
TSAHATNKTEHSHVANQAFCDFGDSLYLDTQSEEIIEQMATKNATQGAEAAGITEEGSATQNEP
HSTTGGQHIPGAANTDHVDRKNTESVKENPEKNIDRRTPHSLIFHSPTPQGGNSACFKENEHSV
TDSQLNSFLQGLETQDKPIIPLAPQMRTSTGVEEESLPETSLNMSDSILFDSFGEDSFGQRQSL
DVKAKQPLLSEMTPNHFHNPPYPQEDPVMTPHMSEPQGTLERMACLSGESIIFSEIDSAQVIEA
LDNMAAFYMQENCNPITLKTEPRDLAALGNECPQGEVVRGEQHEGSSKPKFMEINQDNSFTWSA
ASFNLSPELQRILDKVSTPRENEEPELMHADLSCFEENSTESHERQDMNSDLGTVQRTSFLPSN
GVKSRTEGLESKAKHGGASSALPHKAAADDNGLIPPTPLPASASASASKLALPEILGTSVKHQK
ASCLFDSPSDNQNQDLSQELRDSLKDSDGSVVDTSFFLQSQDGLLLTQASCSSESLAIIDVASD
QILFQTFVKEWQCQKRFSISLACEKMTSSTSSKTATIGGRLKQVNSPQEASVEDDGFPVHGSDC
AVVVGLAVCWGGKDAYYLSLQKEQKQSEMSPSLAPPPLDATLTVKERMEYLQSCLQKKSDQERS
VVTYDFIQTYKVLLLSCGISLEPSYEDPKVACWLLDPDSKEPTLHSIVTSFLPHELALLEGIET
GPGIQSLGLNVNTDHSGRYRASVESVLIFNSMNQLNSMLQKENLHDIFCKVEMPSQYCLALLEL
NGIGFSTAECETQKHIMQAKLDAIETQAYQLAGHSFSFTSADDIAQVLFLELKLPPNGEMKTQG
GRKTLGSTRRGTESDRKLRLGRRFSTSKDILNKLKDLHPLPGLILEWRRISNAITKVVFPLQRE
KHLNPFLRMERIYPVSQSHTATGRITFTEPNIQNVPRDFEIKMPTLVRESPPSQASGKGQLAMA
RQNQKVYGLHPGQRTVLEKTSDRGVPFSVSMRHAFVPFPGGLILAADYSQLELRILAHLSRDCR
LIQVLNSGADVFRSIAAEWKMIEPDAVGDNLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAAC
YIDSFKSRYKGINHFMRDTVKNCRRDGFVETILGRRRYLPGIKDNNPYHKAHAERQAINTTVQG
SAADIVKVATVNIQKQLETFHPTFKSHGHRESMLQSDRAGLLPKRKVKGMFCPMRGGFFILQLH
DELLYEVAEEDVVQVAQIVKNEMECAIKLSVKLKVKVKIGASWGELKDFDV

hide sequence

Ensembl Acc Id:

ENSRNOP00000061230 ⟸ ENSRNOT00000063995

RefSeq Acc Id:	XP_038944052 ⟸ XM_039088124
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038944054 ⟸ XM_039088126
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038944053 ⟸ XM_039088125
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063126449 ⟸ XM_063270379
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063126451 ⟸ XM_063270381
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063126450 ⟸ XM_063270380
- Peptide Label:	isoform X2

Protein Domains

Helicase ATP-binding Helicase C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A628-F1-model_v2	AlphaFold	D4A628	1-2547	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309795	AgrOrtholog
BioCyc Gene	G2FUF-21250	BioCyc
Ensembl Genes	ENSRNOG00000002471	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000063995	ENTREZGENE
	ENSRNOT00000063995.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.3380.20	UniProtKB/TrEMBL
	3.30.420.10	UniProtKB/TrEMBL
	3.30.70.370	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
	5' to 3' exonuclease, C-terminal subdomain	UniProtKB/TrEMBL
	Taq DNA Polymerase, Chain T, domain 4	UniProtKB/TrEMBL
InterPro	DNA-dir_DNA_pol_A_CS	UniProtKB/TrEMBL
	DNA-dir_DNA_pol_A_palm_dom	UniProtKB/TrEMBL
	DNA/RNA_helicase_DEAD/DEAH_N	UniProtKB/TrEMBL
	DNA/RNA_pol_sf	UniProtKB/TrEMBL
	DNA_polymerase_A	UniProtKB/TrEMBL
	Helicase_ATP-bd	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
	HTH_61	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	POLQ-like_helical	UniProtKB/TrEMBL
	RNaseH-like_dom	UniProtKB/TrEMBL
	RNaseH_sf	UniProtKB/TrEMBL
KEGG Report	rno:288079	UniProtKB/TrEMBL
NCBI Gene	288079	ENTREZGENE
PANTHER	DNA POLYMERASE THETA	UniProtKB/TrEMBL
	PTHR10133	UniProtKB/TrEMBL
Pfam	DEAD	UniProtKB/TrEMBL
	DNA_pol_A	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
	HTH_61	UniProtKB/TrEMBL
	POLQ_helical	UniProtKB/TrEMBL
PhenoGen	Polq	PhenoGen
PRINTS	DNAPOLI	UniProtKB/TrEMBL
PROSITE	DNA_POLYMERASE_A	UniProtKB/TrEMBL
	HELICASE_ATP_BIND_1	UniProtKB/TrEMBL
	HELICASE_CTER	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000002471	RatGTEx
SMART	DEXDc	UniProtKB/TrEMBL
	HELICc	UniProtKB/TrEMBL
	POLAc	UniProtKB/TrEMBL
Superfamily-SCOP	RNaseH_fold	UniProtKB/TrEMBL
	Sec63 N-terminal domain-like	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
	SSF56672	UniProtKB/TrEMBL
UniProt	A6IR96	ENTREZGENE, UniProtKB/TrEMBL
	D4A628	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-21	Polq	DNA polymerase theta	Polq	polymerase (DNA) theta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-03-09	Polq	polymerase (DNA) theta	Polq	polymerase (DNA directed), theta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Polq	polymerase (DNA directed), theta	Polq_predicted	polymerase (DNA directed), theta (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Polq_predicted	polymerase (DNA directed), theta (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar