Trim16 (tripartite motif-containing 16) - Rat Genome Database

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Gene: Trim16 (tripartite motif-containing 16) Rattus norvegicus
Analyze
Symbol: Trim16 (Ensembl: Fbxw10)
Name: tripartite motif-containing 16
RGD ID: 1309749
Description: Predicted to be involved in positive regulation of autophagy. Orthologous to several human genes including FBXW10 (F-box and WD repeat domain containing 10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC303214; MGC93671; tripartite motif protein 16; tripartite motif-containing protein 16
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Pia26
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,985,235 - 48,008,242 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1047,958,677 - 48,051,136 (+)EnsemblGRCr8
mRatBN7.21047,485,982 - 47,509,010 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1047,486,297 - 47,551,907 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1052,189,625 - 52,212,030 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01051,680,165 - 51,702,570 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01047,183,586 - 47,205,991 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01049,231,660 - 49,254,653 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1049,231,730 - 49,254,621 (+)Ensemblrn6Rnor6.0
Rnor_5.01049,011,305 - 49,033,997 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41048,987,004 - 49,009,696 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1046,731,462 - 46,754,204 (+)NCBICelera
RGSC_v3.11049,000,664 - 49,021,215 (+)NCBI
Cytogenetic Map10q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-phenylprop-2-enal  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
ampicillin  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzylpenicillin  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
curcumin  (ISO)
decabromodiphenyl ether  (EXP,ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
diquat  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
isoeugenol  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
permethrin  (EXP)
phenoxymethylpenicillin  (ISO)
progesterone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trans-isoeugenol  (ISO)
vanillin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (ISO)
PML body  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9817599   PMID:11919186   PMID:12477932   PMID:16079077   PMID:16575408   PMID:16636064   PMID:19147277   PMID:33391467   PMID:34436665  


Genomics

Comparative Map Data
Trim16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,985,235 - 48,008,242 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1047,958,677 - 48,051,136 (+)EnsemblGRCr8
mRatBN7.21047,485,982 - 47,509,010 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1047,486,297 - 47,551,907 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1052,189,625 - 52,212,030 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01051,680,165 - 51,702,570 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01047,183,586 - 47,205,991 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01049,231,660 - 49,254,653 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1049,231,730 - 49,254,621 (+)Ensemblrn6Rnor6.0
Rnor_5.01049,011,305 - 49,033,997 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41048,987,004 - 49,009,696 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1046,731,462 - 46,754,204 (+)NCBICelera
RGSC_v3.11049,000,664 - 49,021,215 (+)NCBI
Cytogenetic Map10q23NCBI
TRIM16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381715,627,966 - 15,684,311 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1715,627,950 - 15,684,311 (-)Ensemblhg38GRCh38
GRCh371715,531,280 - 15,587,625 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361715,472,005 - 15,526,918 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341715,472,005 - 15,526,918NCBI
Cytogenetic Map17p12NCBI
HuRef1715,404,775 - 15,461,210 (-)NCBIHuRef
CHM1_11715,540,352 - 15,595,047 (-)NCBICHM1_1
T2T-CHM13v2.01715,534,188 - 15,590,551 (-)NCBIT2T-CHM13v2.0
Trim16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,711,034 - 62,733,774 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1162,711,057 - 62,741,634 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381162,820,198 - 62,842,948 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,820,231 - 62,850,808 (+)Ensemblmm10GRCm38
MGSCv371162,633,755 - 62,656,450 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361162,636,448 - 62,659,143 (+)NCBIMGSCv36mm8
Celera1169,742,229 - 69,768,302 (+)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1138.75NCBI
Trim16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554672,059,777 - 2,085,206 (+)Ensembl
ChiLan1.0NW_0049554672,059,793 - 2,084,221 (+)NCBIChiLan1.0ChiLan1.0
TRIM16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21958,070,809 - 58,127,342 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11762,877,474 - 62,934,040 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01735,973,775 - 36,028,767 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TRIM16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1539,146,505 - 39,167,857 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl539,148,868 - 39,213,203 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha539,291,568 - 39,312,872 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0539,254,975 - 39,276,316 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl539,254,781 - 39,321,526 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1539,227,812 - 39,249,105 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0539,173,103 - 39,194,393 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0539,361,457 - 39,382,765 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Trim16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560258,132,028 - 58,170,647 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367242,088,370 - 2,122,170 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367242,101,942 - 2,122,747 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1258,926,086 - 58,939,745 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11258,926,083 - 58,940,642 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TRIM16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11614,874,159 - 14,897,958 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1614,871,657 - 14,897,865 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660596,251,363 - 6,307,941 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trim16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248773,672,925 - 3,713,783 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248773,688,635 - 3,713,718 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Trim16
217 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:269
Count of miRNA genes:171
Interacting mature miRNAs:213
Transcripts:ENSRNOT00000065335
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103589345164140567Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
152025227Bw195Body weight QTL 1955.73body mass (VT:0001259)104748901769161158Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103589326364653589Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103589326352293000Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102937704652699134Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104786912992869129Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
D10Rat85  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81047,993,234 - 47,993,495 (+)Marker Load Pipeline
mRatBN7.21047,494,000 - 47,494,261 (+)MAPPERmRatBN7.2
Rnor_6.01049,239,646 - 49,239,906NCBIRnor6.0
Rnor_5.01049,018,990 - 49,019,250UniSTSRnor5.0
RGSC_v3.41048,994,688 - 48,994,949RGDRGSC3.4
RGSC_v3.41048,994,689 - 48,994,949UniSTSRGSC3.4
Celera1046,739,198 - 46,739,458UniSTS
RGSC_v3.11049,008,312 - 49,008,572RGD
RH 3.4 Map10549.6UniSTS
RH 3.4 Map10549.6RGD
RH 2.0 Map10531.8RGD
SHRSP x BN Map1041.9499RGD
Cytogenetic Map10q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 89 88 57 74 57 6 336 174 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000004390   ⟹   ENSRNOP00000004390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1047,513,330 - 47,551,907 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000065335   ⟹   ENSRNOP00000063404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1047,486,297 - 47,509,009 (+)Ensembl
Rnor_6.0 Ensembl1049,231,730 - 49,254,621 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099929   ⟹   ENSRNOP00000089597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1047,486,297 - 47,517,606 (+)Ensembl
RefSeq Acc Id: NM_001135033   ⟹   NP_001128505
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81047,985,550 - 48,008,242 (+)NCBI
mRatBN7.21047,486,321 - 47,509,009 (+)NCBI
Rnor_6.01049,231,961 - 49,254,653 (+)NCBI
Rnor_5.01049,011,305 - 49,033,997 (+)NCBI
RGSC_v3.41048,987,004 - 49,009,696 (+)RGD
Celera1046,731,462 - 46,754,204 (+)RGD
Sequence:
RefSeq Acc Id: XM_063269015   ⟹   XP_063125085
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81047,985,235 - 48,006,539 (+)NCBI
RefSeq Acc Id: NP_001128505   ⟸   NM_001135033
- UniProtKB: D3ZW47 (UniProtKB/TrEMBL),   A0A8I6GI85 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063404   ⟸   ENSRNOT00000065335
Ensembl Acc Id: ENSRNOP00000004390   ⟸   ENSRNOT00000004390
Ensembl Acc Id: ENSRNOP00000089597   ⟸   ENSRNOT00000099929
RefSeq Acc Id: XP_063125085   ⟸   XM_063269015
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GI85 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZW47-F1-model_v2 AlphaFold D3ZW47 1-557 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309749 AgrOrtholog
BioCyc Gene G2FUF-24750 BioCyc
Ensembl Genes ENSRNOG00000003219 Ensembl
  ENSRNOG00000003287 Ensembl
  ENSRNOG00000071275 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000120793 ENTREZGENE
  ENSRNOT00000120793.2 UniProtKB/TrEMBL
  ENSRNOT00000123252.1 UniProtKB/TrEMBL
  ENSRNOT00000128025.1 UniProtKB/TrEMBL
  ENSRNOT00000143393.1 UniProtKB/TrEMBL
  ENSRNOT00000153868 ENTREZGENE
  ENSRNOT00000153868.1 UniProtKB/TrEMBL
NCBI Gene 303214 ENTREZGENE
PhenoGen Trim16 PhenoGen
RatGTEx ENSRNOG00000003219 RatGTEx
  ENSRNOG00000003287 RatGTEx
  ENSRNOG00000071275 RatGTEx
UniProt A0A8I6GI85 ENTREZGENE
  A0ABK0KW71_RAT UniProtKB/TrEMBL
  A0ABK0L4Q7_RAT UniProtKB/TrEMBL
  A0ABK0L8W2_RAT UniProtKB/TrEMBL
  A0ABK0LFT2_RAT UniProtKB/TrEMBL
  A0ABK0M6V0_RAT UniProtKB/TrEMBL
  D3ZW47 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-05-01 Trim16  tripartite motif-containing 16  Trim16  tripartite motif protein 16   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Trim16  tripartite motif protein 16   Trim16_predicted  tripartite motif protein 16 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Trim16_predicted  tripartite motif protein 16 (predicted)      Symbol and Name status set to approved 70820 APPROVED