Prxl2a (peroxiredoxin like 2A) - Rat Genome Database

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Pathways
Gene: Prxl2a (peroxiredoxin like 2A) Rattus norvegicus
Analyze
Symbol: Prxl2a
Name: peroxiredoxin like 2A
RGD ID: 1309676
Description: Predicted to enable antioxidant activity. Predicted to be involved in regulation of osteoclast differentiation. Predicted to be located in extracellular region. Predicted to be active in cytoplasm. Orthologous to human PRXL2A (peroxiredoxin like 2A); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fam213a; family with sequence similarity 213, member A; hypothetical protein LOC361118; LOC361118; PAMM; peroxiredoxin-like 2 activated in M-CSF stimulated monocytes; peroxiredoxin-like 2A; redox-regulatory protein FAM213A; redox-regulatory protein PAMM; RGD1309676; similar to RIKEN cDNA 5730469M10; sperm head protein 1; UPF0765 protein C10orf58 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81616,900,697 - 16,920,521 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1616,900,699 - 16,920,561 (-)EnsemblGRCr8
mRatBN7.21616,866,601 - 16,886,378 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1616,866,603 - 16,886,433 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1616,930,779 - 16,950,429 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,057,541 - 18,077,191 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01616,983,676 - 17,003,327 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01617,494,000 - 17,513,781 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1617,493,953 - 17,513,870 (+)Ensemblrn6Rnor6.0
Rnor_5.01617,376,841 - 17,396,622 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41617,425,527 - 17,445,308 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1617,092,238 - 17,112,513 (-)NCBICelera
RGSC_v3.11617,425,526 - 17,445,306 (-)NCBI
Cytogenetic Map16p14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dimethoxyphenol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
clofibric acid  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
eugenol  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
furfural  (ISO)
genistein  (ISO)
gentamycin  (EXP)
haloperidol  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
naled  (ISO)
nickel atom  (ISO)
nitrofen  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
potassium chromate  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
tributylstannane  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
extracellular region  (IEA)

Molecular Function
antioxidant activity  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:18614015   PMID:19951071   PMID:23376485   PMID:29476059  


Genomics

Comparative Map Data
Prxl2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81616,900,697 - 16,920,521 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1616,900,699 - 16,920,561 (-)EnsemblGRCr8
mRatBN7.21616,866,601 - 16,886,378 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1616,866,603 - 16,886,433 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1616,930,779 - 16,950,429 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,057,541 - 18,077,191 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01616,983,676 - 17,003,327 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01617,494,000 - 17,513,781 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1617,493,953 - 17,513,870 (+)Ensemblrn6Rnor6.0
Rnor_5.01617,376,841 - 17,396,622 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41617,425,527 - 17,445,308 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1617,092,238 - 17,112,513 (-)NCBICelera
RGSC_v3.11617,425,526 - 17,445,306 (-)NCBI
Cytogenetic Map16p14NCBI
PRXL2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381080,407,829 - 80,437,115 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1080,406,443 - 80,437,115 (+)Ensemblhg38GRCh38
GRCh371082,167,585 - 82,196,871 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361082,158,222 - 82,182,733 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341082,158,277 - 82,182,727NCBI
Celera1076,158,574 - 76,183,083 (+)NCBICelera
Cytogenetic Map10q23.1NCBI
HuRef1076,010,785 - 76,035,953 (+)NCBIHuRef
CHM1_11082,450,611 - 82,475,759 (+)NCBICHM1_1
T2T-CHM13v2.01081,276,927 - 81,306,214 (+)NCBIT2T-CHM13v2.0
Prxl2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391440,715,692 - 40,735,790 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1440,715,697 - 40,735,745 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381440,993,735 - 41,013,833 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1440,993,740 - 41,013,788 (-)Ensemblmm10GRCm38
MGSCv371441,807,029 - 41,827,064 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361439,902,453 - 39,922,488 (-)NCBIMGSCv36mm8
Celera1437,152,444 - 37,172,479 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1422.36NCBI
Prxl2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955510400,469 - 423,056 (+)Ensembl
ChiLan1.0NW_004955510400,454 - 420,900 (+)NCBIChiLan1.0ChiLan1.0
PRXL2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2892,374,121 - 92,398,591 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11092,379,450 - 92,403,912 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01076,808,869 - 76,837,447 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11080,407,861 - 80,432,032 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1080,412,903 - 80,432,032 (+)EnsemblpanPan2panpan1.1
PRXL2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1429,539,182 - 29,559,353 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl429,538,781 - 29,558,961 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha429,664,527 - 29,684,707 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0429,842,305 - 29,862,483 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl429,841,958 - 29,862,479 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1429,711,907 - 29,732,079 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0429,914,243 - 29,934,411 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0430,268,661 - 30,288,845 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Prxl2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721351,144,036 - 51,163,838 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936716246,345 - 266,531 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936716246,735 - 266,513 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRXL2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1482,249,452 - 82,271,214 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11482,249,450 - 82,271,227 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21488,856,827 - 88,878,595 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRXL2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1951,403,837 - 51,428,015 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl951,404,808 - 51,427,599 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604811,725,400 - 11,751,897 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prxl2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248416,671,604 - 6,682,854 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248416,672,204 - 6,690,991 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Prxl2a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11319,508,763 - 19,528,262 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Prxl2a
350 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:296
Count of miRNA genes:199
Interacting mature miRNAs:234
Transcripts:ENSRNOT00000014819
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161574800625801629Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)161627818427244292Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16423433317730812Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat

Markers in Region
RH134489  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2161,504,078 - 1,504,283 (-)MAPPERmRatBN7.2
Rnor_6.0163,820,918 - 3,821,122NCBIRnor6.0
Rnor_5.0163,786,961 - 3,787,165UniSTSRnor5.0
RGSC_v3.4161,542,394 - 1,542,598UniSTSRGSC3.4
Celera161,479,882 - 1,480,086UniSTS
Cytogenetic Map16p16UniSTS
BI286434  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21616,866,666 - 16,866,835 (-)MAPPERmRatBN7.2
Rnor_6.01617,513,548 - 17,513,719NCBIRnor6.0
Rnor_5.01617,396,389 - 17,396,560UniSTSRnor5.0
RGSC_v3.41617,425,589 - 17,425,760UniSTSRGSC3.4
Celera1617,092,300 - 17,092,471UniSTS
RH 3.4 Map16164.11UniSTS
Cytogenetic Map16p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 355 192 11 141 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000014819   ⟹   ENSRNOP00000014819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1616,900,699 - 16,920,561 (-)Ensembl
mRatBN7.2 Ensembl1616,866,603 - 16,886,433 (-)Ensembl
Rnor_6.0 Ensembl1617,493,953 - 17,513,870 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113272   ⟹   ENSRNOP00000078597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1616,900,699 - 16,914,279 (-)Ensembl
mRatBN7.2 Ensembl1616,866,603 - 16,880,274 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000158328   ⟹   ENSRNOP00000102558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1616,900,699 - 16,914,496 (-)Ensembl
RefSeq Acc Id: NM_001014140   ⟹   NP_001014162
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81616,900,697 - 16,920,478 (-)NCBI
mRatBN7.21616,866,601 - 16,886,378 (-)NCBI
Rnor_6.01617,494,000 - 17,513,781 (+)NCBI
Rnor_5.01617,376,841 - 17,396,622 (+)NCBI
RGSC_v3.41617,425,527 - 17,445,308 (-)RGD
Celera1617,092,238 - 17,112,513 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252791   ⟹   XP_006252853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81616,900,697 - 16,914,486 (-)NCBI
mRatBN7.21616,866,601 - 16,880,389 (-)NCBI
Rnor_6.01617,500,028 - 17,513,781 (+)NCBI
Rnor_5.01617,376,841 - 17,396,622 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063275493   ⟹   XP_063131563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81616,900,697 - 16,920,521 (-)NCBI
RefSeq Acc Id: NP_001014162   ⟸   NM_001014140
- UniProtKB: P85300 (UniProtKB/Swiss-Prot),   Q6AXX6 (UniProtKB/Swiss-Prot),   A6K9L0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252853   ⟸   XM_006252791
- Peptide Label: isoform X2
- UniProtKB: P85300 (UniProtKB/Swiss-Prot),   Q6AXX6 (UniProtKB/Swiss-Prot),   A6K9L0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014819   ⟸   ENSRNOT00000014819
Ensembl Acc Id: ENSRNOP00000078597   ⟸   ENSRNOT00000113272
RefSeq Acc Id: XP_063131563   ⟸   XM_063275493
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q6Y2 (UniProtKB/TrEMBL),   A0A8I6G216 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102558   ⟸   ENSRNOT00000158328

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXX6-F1-model_v2 AlphaFold Q6AXX6 1-229 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699968
Promoter ID:EPDNEW_R10491
Type:initiation region
Name:Fam213a_1
Description:family with sequence similarity 213, member A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01617,493,962 - 17,494,022EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309676 AgrOrtholog
BioCyc Gene G2FUF-11913 BioCyc
Ensembl Genes ENSRNOG00000011140 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000014819 ENTREZGENE
  ENSRNOT00000113272 ENTREZGENE
  ENSRNOT00000158328 ENTREZGENE
Gene3D-CATH Glutaredoxin UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134042 IMAGE-MGC_LOAD
InterPro PXL2A/B/C UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:361118 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94395 IMAGE-MGC_LOAD
NCBI Gene 361118 ENTREZGENE
PANTHER PEROXIREDOXIN-LIKE 2A UniProtKB/Swiss-Prot
  PTHR28630 UniProtKB/Swiss-Prot
Pfam AhpC-TSA_2 UniProtKB/Swiss-Prot
PhenoGen Prxl2a PhenoGen
RatGTEx ENSRNOG00000011140 RatGTEx
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot
UniProt A0A8I6G216 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q6Y2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L1X3_RAT UniProtKB/TrEMBL
  A6K9L0 ENTREZGENE, UniProtKB/TrEMBL
  P85300 ENTREZGENE
  PXL2A_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P85300 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-07-26 Prxl2a  peroxiredoxin like 2A  Fam213a  family with sequence similarity 213, member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-10 Fam213a  family with sequence similarity 213, member A  RGD1309676  similar to RIKEN cDNA 5730469M10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1309676  similar to RIKEN cDNA 5730469M10  RGD1309676_predicted  similar to RIKEN cDNA 5730469M10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309676_predicted  similar to RIKEN cDNA 5730469M10 (predicted)  LOC361118_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361118_predicted  similar to RIKEN cDNA 5730469M10 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL