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Gene: P4ha2 (prolyl 4-hydroxylase subunit alpha 2) Rattus norvegicus

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Symbol:

P4ha2

Name:

prolyl 4-hydroxylase subunit alpha 2

RGD ID:

1309673

Description:

Predicted to enable procollagen-proline 4-dioxygenase activity. Predicted to be located in cytosol; endoplasmic reticulum lumen; and nucleoplasm. Predicted to be part of procollagen-proline 4-dioxygenase complex. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in myopia. Orthologous to human P4HA2 (prolyl 4-hydroxylase subunit alpha 2); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC360526; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II; prolyl 4-hydroxylase subunit alpha-2; prolyl 4-hydroxylase, alpha polypeptide II

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	38,743,894 - 38,772,741 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	38,743,894 - 38,772,993 (+)	Ensembl				GRCr8
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	38,243,139 - 38,287,314 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	42,928,504 - 42,957,355 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	42,418,604 - 42,447,453 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	37,922,310 - 37,951,165 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	39,435,227 - 39,464,134 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	39,435,227 - 39,464,188 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	39,214,791 - 39,243,698 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	39,522,157 - 39,551,063 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	37,584,460 - 37,613,368 (+)	NCBI		Celera
RGSC_v3.1	10	39,535,833 - 39,564,271 (+)	NCBI
Cytogenetic Map	10	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Myopia 25, Autosomal Dominant (ISO)

retinitis pigmentosa 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,10-phenanthroline (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

5-chloro-7-iodoquinolin-8-ol (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP,ISO)

calciol (ISO)

calcium silicate (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (EXP,ISO)

cyclosporin A (ISO)

cytarabine (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

diclofenac (ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

dioxygen (ISO)

diquat (ISO)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (ISO)

fentanyl (EXP)

fluoranthene (ISO)

folic acid (ISO)

ivermectin (ISO)

L-ascorbic acid (ISO)

L-methionine (ISO)

lead diacetate (ISO)

lead(0) (ISO)

methamphetamine (EXP)

N(4)-hydroxycytidine (ISO)

nickel dichloride (EXP,ISO)

nickel subsulfide (ISO)

nickel sulfate (ISO)

okadaic acid (ISO)

oxaliplatin (EXP,ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

potassium dichromate (EXP)

progesterone (ISO)

propiconazole (ISO)

SB 431542 (ISO)

SCH 23390 (EXP)

serpentine asbestos (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

tetrachloromethane (EXP,ISO)

thifluzamide (ISO)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc dichloride (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

peptidyl-proline hydroxylation to 4-hydroxy-L-proline (ISO)

Cellular Component

endoplasmic reticulum (IBA,IEA,ISO)

endoplasmic reticulum lumen (IEA)

procollagen-proline 4-dioxygenase complex (IEA,ISO)

Molecular Function

dioxygenase activity (IEA)

iron ion binding (IEA)

L-ascorbic acid binding (IEA)

metal ion binding (IEA)

oxidoreductase activity (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (IEA)

procollagen-proline 4-dioxygenase activity (IBA,IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

arginine and proline metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7753822

Genomics

Comparative Map Data

P4ha2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	38,743,894 - 38,772,741 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	38,743,894 - 38,772,993 (+)	Ensembl				GRCr8
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	38,243,139 - 38,287,314 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	42,928,504 - 42,957,355 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	42,418,604 - 42,447,453 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	37,922,310 - 37,951,165 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	39,435,227 - 39,464,134 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	39,435,227 - 39,464,188 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	39,214,791 - 39,243,698 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	39,522,157 - 39,551,063 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	37,584,460 - 37,613,368 (+)	NCBI		Celera
RGSC_v3.1	10	39,535,833 - 39,564,271 (+)	NCBI
Cytogenetic Map	10	q22	NCBI

P4HA2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	132,190,147 - 132,227,853 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	132,190,094 - 132,295,315 (-)	Ensembl			hg38	GRCh38
GRCh37	5	131,525,840 - 131,563,546 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	131,556,202 - 131,591,455 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	131,556,201 - 131,590,458	NCBI
Celera	5	127,658,410 - 127,693,660 (-)	NCBI		Celera
Cytogenetic Map	5	q31.1	NCBI
HuRef	5	126,720,651 - 126,756,017 (-)	NCBI		HuRef
CHM1_1	5	130,961,055 - 130,996,320 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	132,710,021 - 132,747,731 (-)	NCBI		T2T-CHM13v2.0

P4ha2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	53,991,750 - 54,022,494 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	53,990,921 - 54,022,491 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	54,100,924 - 54,131,668 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	54,100,095 - 54,131,665 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	53,914,426 - 53,945,169 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	53,944,939 - 53,975,071 (+)	NCBI		MGSCv36	mm8
Celera	11	58,688,554 - 58,719,297 (+)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	32.13	NCBI

P4ha2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	3,574,860 - 3,607,015 (-)	Ensembl
ChiLan1.0	NW_004955408	3,574,860 - 3,607,015 (-)	NCBI	ChiLan1.0	ChiLan1.0

P4HA2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	127,447,132 - 127,546,038 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	125,583,719 - 125,685,655 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	127,613,037 - 127,650,647 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	133,778,520 - 133,813,779 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	133,778,520 - 133,813,779 (-)	Ensembl			panPan2	panpan1.1

P4HA2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	20,514,982 - 20,548,261 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	20,514,978 - 20,549,541 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	19,310,369 - 19,350,017 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	21,300,346 - 21,333,655 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	21,300,356 - 21,333,637 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	20,019,425 - 20,052,694 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	19,867,545 - 19,900,820 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	20,509,393 - 20,542,685 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

P4ha2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	115,927,933 - 115,960,406 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936647	2,930,494 - 2,964,550 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936647	2,930,748 - 2,963,168 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

P4HA2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	134,502,212 - 134,595,430 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	134,502,210 - 134,595,444 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	139,853,792 - 139,886,023 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

P4HA2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	35,022,675 - 35,058,128 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	35,020,535 - 35,058,009 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666034	42,885,975 - 42,923,550 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

P4ha2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	39,871,180 - 39,903,377 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624733	39,871,156 - 39,902,266 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

P4ha2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	36,568,982 - 36,590,304 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in P4ha2
107 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	89
Count of miRNA genes:	74
Interacting mature miRNAs:	87
Transcripts:	ENSRNOT00000042144
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35893451	64140567	Rat
152025229	Scl83	Serum cholesterol level QTL 83	4.33		blood cholesterol amount (VT:0000180)		10	36211556	69161158	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31796281	76796281	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15776754	60776754	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	27023535	98502431	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	27443787	72443787	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	35509383	91417879	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	19939207	64939207	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	18035782	63035782	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18668419	63668419	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21833758	61843633	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28950353	73950353	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35893263	64653589	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29800910	64653589	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	27443787	72443787	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22931373	91127454	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
634329	Pia15	Pristane induced arthritis QTL 15	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	24662123	73695339	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	27023535	61843633	Rat
2298480	Eau7	Experimental allergic uveoretinitis QTL 7		0.0049	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	35509383	80509383	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29800910	91417879	Rat
2298495	Eae23	Experimental allergic encephalomyelitis QTL 23	16.93		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	10	16175525	61175525	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	20110614	65110614	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat
1354614	Hpcl1	Hepatic cholesterol level QTL 1	3.3		liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	35893263	52293000	Rat
2289985	Bp305	Blood pressure QTL 305			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	29076978	74076978	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	27587226	96099902	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	18035782	63035782	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
1600371	Mcs21	Mammary carcinoma susceptibility QTL 21	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	29377046	52699134	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	27443787	72443787	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31129113	76129113	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	35509383	88177745	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	20110614	65110614	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	27023535	99451848	Rat

Markers in Region

BI276296

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	10	38,772,508 - 38,772,671 (+)	Marker Load Pipeline
mRatBN7.2	10	38,271,750 - 38,271,913 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	39,463,896 - 39,464,058	NCBI	Rnor6.0
Rnor_5.0	10	39,243,460 - 39,243,622	UniSTS	Rnor5.0
RGSC_v3.4	10	39,550,825 - 39,550,987	UniSTS	RGSC3.4
Celera	10	37,613,130 - 37,613,292	UniSTS
RH 3.4 Map	10	413.5	UniSTS
Cytogenetic Map	10	q22	UniSTS

UniSTS:546912

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	38,271,480 - 38,271,917 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	39,463,626 - 39,464,062	NCBI	Rnor6.0
Rnor_5.0	10	39,243,190 - 39,243,626	UniSTS	Rnor5.0
Celera	10	37,612,860 - 37,613,296	UniSTS
Cytogenetic Map	10	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	52	59	6	316	152	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399543	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000042144 ⟹ ENSRNOP00000048172

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	38,243,142 - 38,271,990 (+)	Ensembl
Rnor_6.0 Ensembl	10	39,435,227 - 39,464,134 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000077185 ⟹ ENSRNOP00000070701

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	38,743,894 - 38,772,993 (+)	Ensembl
mRatBN7.2 Ensembl	10	38,243,139 - 38,271,991 (+)	Ensembl
Rnor_6.0 Ensembl	10	39,435,283 - 39,464,188 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104075 ⟹ ENSRNOP00000089755

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	38,743,894 - 38,772,741 (+)	Ensembl
mRatBN7.2 Ensembl	10	38,243,196 - 38,271,967 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106136 ⟹ ENSRNOP00000097385

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	38,743,958 - 38,772,729 (+)	Ensembl
mRatBN7.2 Ensembl	10	38,243,175 - 38,287,314 (+)	Ensembl

RefSeq Acc Id:

NM_001108275 ⟹ NP_001101745

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,894 - 38,772,741 (+)	NCBI
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI
Rnor_6.0	10	39,435,227 - 39,464,134 (+)	NCBI
Rnor_5.0	10	39,214,791 - 39,243,698 (+)	NCBI
RGSC_v3.4	10	39,522,157 - 39,551,063 (+)	RGD
Celera	10	37,584,460 - 37,613,368 (+)	RGD

Sequence:

show sequence

GCGGGAGGTGGGGATCGTGGCGGAGGCTCAAGCAGGCGGAGCTTCTGACGAGGGCGGAGCCGAG
AGCGCCCGGGCGACGCCGCGGGAGGTTCTGGAAACGCCGGCTGCTGCGCGTGTCCAGTTTCAGA
GACCGGTGGCGATTGGCTGACTGATTCAACAAATAGAGCATTCTCTGTGCCTGGAGACTTTCAA
GGACGGAGGCAGGCAGAAGGGAAGACTCAGAAAGTCCGTGTCCAGAGCACCGGCAAGGTCCCGC
CCTTTCCAGTCATGAAGCTCCAGGTGTTGGTGTTGCTGATGTCCTGGTTTGGTGTCCTGAGCTG
GGTGCAGGCGGAATTCTTCACCTCCATTGGGCACATGACCGACCTGATTTATGCAGAGAAGGAC
CTCGTCCAGTCTCTGAAGGAGTACATCCTGGCAGAGGAAGCCAAGCTCTCCAAGATTAAGAGCT
GGGCCAGTAAGATGGAGGCCCTGACCAGCAAGTCAGCTGCTGACCCCGAGGGCTACCTGGCCCA
TCCTGTGAACGCCTATAAGCTGGTGAAGCGATTGAACACAGACTGGCCTGCCCTGGGGGACCTT
GTCCTCCAGGACGCGGCTGCAGGTTTTGTGGCTAACCTCTCAGTTCAGCGGCAGTTCTTCCCCA
CTGACGAGGACGAGTCTGGAGCTGCCAGAGCCCTGATGCGACTTCAGGACACCTACAAACTGGA
TCCGGACATGATTTCTAGAGGGGAGCTTCCAGGAACAAAGTACCAGGCCATGCTGAGTGTGGAT
GACTGCTTTGGGATGGGCCGCTCAGCTTACAACGAAGGAGACTATTACCACACCGTGTTGTGGA
TGGAGCAGGTGCTGAAGCAGCTGGATGCTGGGGAGGAGGCCACTGTTACCAAATCCCTGGTGCT
GGACTACCTGAGCTATGCCGTCTTCCAGCTGGGTGACCTGCACCGTGCGGTGGAACTCACCCGT
CGCCTGCTCTCTCTTGACCCGAGCCATGAACGAGCCGGAGGGAACCTGCGGTACTTTGAGCGGC
TGTTAGAGGAAGAAAGAGGAAAATCATTGTCGAATCAGACGGACGCTGGACTAGCATCGCAGGA
AAACTTGTACGAGAGGCCTGTAGACTACCTGCCCGAGAGGGACGTGTATGAGAGCCTGTGTCGA
GGGGAGGGCATCAAAATGACACCCCGGAGGCAGAAGAGGCTTTTCTGTAGATACCACCATGGAA
ACAGAGTGCCACAGCTCCTCATTGCCCCCTTCAAAGAGGAAGACGAGTGGGACAGCCCACACAT
CGTCAGGTACTATGATGTGATGTCGGACGAAGAGATCGAGAGGATCAAGGAGATTGCTAAGCCC
AAACTCGCACGAGCCACTGTGCGTGATCCCAAGACAGGTGTCCTCACTGTTGCTAGCTACAGAG
TTTCCAAAAGCTCCTGGCTAGAGGAAGACGATGACCCTGTTGTGGCCCGAGTCAACCGCAGGAT
GCAGCACATCACAGGGCTGACGGTGAAGACTGCAGAGCTATTGCAGGTCGCAAACTACGGAATG
GGGGGACAGTACGAACCACACTTTGACTTCTCGAGGAGCGATGAGCGAGATGCTTTCAAGCGTT
TAGGGACTGGGAACCGTGTGGCCACATTTCTAAACTACATGAGTGATGTTGAAGCTGGTGGCGC
CACTGTCTTCCCCGACTTGGGAGCTGCGATTTGGCCCAAGAAGGGCACGGCTGTATTTTGGTAT
AACCTTCTTCGGAGCGGGGAAGGCGATTATCGAACGAGGCACGCGGCCTGCCCTGTGCTTGTGG
GCTGCAAGTGGGTCTCCAATAAGTGGTTCCATGAGCGAGGACAGGAGTTCTTGAGGCCTTGTGG
GACAACGGAAGTCGATTGACGTCCTTTTCTGCTCTGCCCCTCCCTGTCCCACAGTCCAAATCAT
CTTCAAGTTCAGTGTGACAGCTTCCTTTGTATGTCCCAGCTCCTGTCAAGCAGGCCATTGGGGG
AGCCAGTGTTTGTCTGAATTGAGAGAGTGTGTCCTGAGCCGAGTCCTGGGTGACCTGGGCCGCA
GGCTCTGGCCAGCCTATGCCTGCCCTGGCTCCCAGGGTAGTCTTGTCATGGCTGTAGTAGAGCC
AGACTGTAGCACCCAGCACGGTGCCTTTGTACCTCAGATATTTCAGGTGGACGATGTTTCAGTG
AAACCAAAGTTCTGACACTGTTTACATGTTTGTTTTCTATGACATTTCTATTTGTTGTGGCTTT
AACCAAAAAATAAAATAAAACAAAACAAAACAAAATAAAATGTTCCTGCCAGAAGCCTTAAAGA
GCTTTACTTCGG

hide sequence

RefSeq Acc Id:

NM_001399539 ⟹ NP_001386468

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,894 - 38,772,741 (+)	NCBI
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

NM_001399540 ⟹ NP_001386469

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,894 - 38,772,741 (+)	NCBI
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

NM_001399541 ⟹ NP_001386470

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,894 - 38,772,741 (+)	NCBI
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

NM_001399542 ⟹ NP_001386471

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,894 - 38,772,741 (+)	NCBI
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

NM_001399543 ⟹ NP_001386472

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,894 - 38,772,741 (+)	NCBI
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

XM_008767691 ⟹ XP_008765913

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,941 - 38,772,741 (+)	NCBI
mRatBN7.2	10	38,243,280 - 38,271,983 (+)	NCBI
Rnor_6.0	10	39,435,421 - 39,464,128 (+)	NCBI

Sequence:

show sequence

CGCGGAGCCGGGAGCTGGATCCGGGGTCACTCAGTCTCGCTCTCGGCGCCCTGATTCTGCACCC
GCCTGGGTTCCTGTTCCCGCCCGTGTCCCTTCCCAGGGTTAGGGCGGTGAGTTTCAGAGACCGG
TGGCGATTGGCTGACTGATTCAACAAATAGAGCATTCTCTGTGCCTGGAGACTTTCAAGGACGG
AGGCAGGCAGAAGGGAAGACTCAGAAAGTCCGTGTCCAGAGCACCGGCAAGGTCCCGCCCTTTC
CAGTCATGAAGCTCCAGGTGTTGGTGTTGCTGATGTCCTGGTTTGGTGTCCTGAGCTGGGTGCA
GGCGGAATTCTTCACCTCCATTGGGCACATGACCGACCTGATTTATGCAGAGAAGGACCTCGTC
CAGTCTCTGAAGGAGTACATCCTGGCAGAGGAAGCCAAGCTCTCCAAGATTAAGAGCTGGGCCA
GTAAGATGGAGGCCCTGACCAGCAAGTCAGCTGCTGACCCCGAGGGCTACCTGGCCCATCCTGT
GAACGCCTATAAGCTGGTGAAGCGATTGAACACAGACTGGCCTGCCCTGGGGGACCTTGTCCTC
CAGGACGCGGCTGCAGGTTTTGTGGCTAACCTCTCAGTTCAGCGGCAGTTCTTCCCCACTGACG
AGGACGAGTCTGGAGCTGCCAGAGCCCTGATGCGACTTCAGGACACCTACAAACTGGATCCGGA
CATGATTTCTAGAGGGGAGCTTCCAGGAACAAAGTACCAGGCCATGCTGAGTGTGGATGACTGC
TTTGGGATGGGCCGCTCAGCTTACAACGAAGGAGACTATTACCACACCGTGTTGTGGATGGAGC
AGGTGCTGAAGCAGCTGGATGCTGGGGAGGAGGCCACTGTTACCAAATCCCTGGTGCTGGACTA
CCTGAGCTATGCCGTCTTCCAGCTGGGTGACCTGCACCGTGCGGTGGAACTCACCCGTCGCCTG
CTCTCTCTTGACCCGAGCCATGAACGAGCCGGAGGGAACCTGCGGTACTTTGAGCGGCTGTTAG
AGGAAGAAAGAGGAAAATCATTGTCGAATCAGACGGACGCTGGACTAGCATCGCAGGAAAACTT
GTACGAGAGGCCTGTAGACTACCTGCCCGAGAGGGACGTGTATGAGAGCCTGTGTCGAGGGGAG
GGCATCAAAATGACACCCCGGAGGCAGAAGAGGCTTTTCTGTAGATACCACCATGGAAACAGAG
TGCCACAGCTCCTCATTGCCCCCTTCAAAGAGGAAGACGAGTGGGACAGCCCACACATCGTCAG
GTACTATGATGTGATGTCGGACGAAGAGATCGAGAGGATCAAGGAGATTGCTAAGCCCAAACTC
GCACGAGCCACTGTGCGTGATCCCAAGACAGGTGTCCTCACTGTTGCTAGCTACAGAGTTTCCA
AAAGCTCCTGGCTAGAGGAAGACGATGACCCTGTTGTGGCCCGAGTCAACCGCAGGATGCAGCA
CATCACAGGGCTGACGGTGAAGACTGCAGAGCTATTGCAGGTCGCAAACTACGGAATGGGGGGA
CAGTACGAACCACACTTTGACTTCTCGAGGAGCGATGAGCGAGATGCTTTCAAGCGTTTAGGGA
CTGGGAACCGTGTGGCCACATTTCTAAACTACATGAGTGATGTTGAAGCTGGTGGCGCCACTGT
CTTCCCCGACTTGGGAGCTGCGATTTGGCCCAAGAAGGGCACGGCTGTATTTTGGTATAACCTT
CTTCGGAGCGGGGAAGGCGATTATCGAACGAGGCACGCGGCCTGCCCTGTGCTTGTGGGCTGCA
AGTGGGTCTCCAATAAGTGGTTCCATGAGCGAGGACAGGAGTTCTTGAGGCCTTGTGGGACAAC
GGAAGTCGATTGACGTCCTTTTCTGCTCTGCCCCTCCCTGTCCCACAGTCCAAATCATCTTCAA
GTTCAGTGTGACAGCTTCCTTTGTATGTCCCAGCTCCTGTCAAGCAGGCCATTGGGGGAGCCAG
TGTTTGTCTGAATTGAGAGAGTGTGTCCTGAGCCGAGTCCTGGGTGACCTGGGCCGCAGGCTCT
GGCCAGCCTATGCCTGCCCTGGCTCCCAGGGTAGTCTTGTCATGGCTGTAGTAGAGCCAGACTG
TAGCACCCAGCACGGTGCCTTTGTACCTCAGATATTTCAGGTGGACGATGTTTCAGTGAAACCA
AAGTTCTGACACTGTTTACATGTTTGTTTTCTATGACATTTCTATTTGTTGTGGCTTTAACCAA
AAAATAAAATAAAACAAAACAAAACAAAATAAAATGTTCCTGCCAGAAGCCTTAAAGAGCTTTA

hide sequence

RefSeq Acc Id:

XM_017597370 ⟹ XP_017452859

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,969 - 38,772,741 (+)	NCBI
mRatBN7.2	10	38,243,238 - 38,271,983 (+)	NCBI
Rnor_6.0	10	39,435,358 - 39,464,128 (+)	NCBI

Sequence:

show sequence

TCTGCGGGGTCGTCGTCCGGGCTGGCCTCGGGTCCCGGTGACCCGGCGTTTCAGAGACCGGTGG
CGATTGGCTGACTGATTCAACAAATAGAGCATTCTCTGTGCCTGGAGACTTTCAAGGACGGAGG
CAGGCAGAAGGGAAGACTCAGAAAGTCCGTGTCCAGAGCACCGGCAAGGTCCCGCCCTTTCCAG
TCATGAAGCTCCAGGTGTTGGTGTTGCTGATGTCCTGGTTTGGTGTCCTGAGCTGGGTGCAGGC
GGAATTCTTCACCTCCATTGGGCACATGACCGACCTGATTTATGCAGAGAAGGACCTCGTCCAG
TCTCTGAAGGAGTACATCCTGGCAGAGGAAGCCAAGCTCTCCAAGATTAAGAGCTGGGCCAGTA
AGATGGAGGCCCTGACCAGCAAGTCAGCTGCTGACCCCGAGGGCTACCTGGCCCATCCTGTGAA
CGCCTATAAGCTGGTGAAGCGATTGAACACAGACTGGCCTGCCCTGGGGGACCTTGTCCTCCAG
GACGCGGCTGCAGGTTTTGTGGCTAACCTCTCAGTTCAGCGGCAGTTCTTCCCCACTGACGAGG
ACGAGTCTGGAGCTGCCAGAGCCCTGATGCGACTTCAGGACACCTACAAACTGGATCCGGACAT
GATTTCTAGAGGGGAGCTTCCAGGAACAAAGTACCAGGCCATGCTGAGTGTGGATGACTGCTTT
GGGATGGGCCGCTCAGCTTACAACGAAGGAGACTATTACCACACCGTGTTGTGGATGGAGCAGG
TGCTGAAGCAGCTGGATGCTGGGGAGGAGGCCACTGTTACCAAATCCCTGGTGCTGGACTACCT
GAGCTATGCCGTCTTCCAGCTGGGTGACCTGCACCGTGCGGTGGAACTCACCCGTCGCCTGCTC
TCTCTTGACCCGAGCCATGAACGAGCCGGAGGGAACCTGCGGTACTTTGAGCGGCTGTTAGAGG
AAGAAAGAGGAAAATCATTGTCGAATCAGACGGACGCTGGACTAGCATCGCAGGAAAACTTGTA
CGAGAGGCCTGTAGACTACCTGCCCGAGAGGGACGTGTATGAGAGCCTGTGTCGAGGGGAGGGC
ATCAAAATGACACCCCGGAGGCAGAAGAGGCTTTTCTGTAGATACCACCATGGAAACAGAGTGC
CACAGCTCCTCATTGCCCCCTTCAAAGAGGAAGACGAGTGGGACAGCCCACACATCGTCAGGTA
CTATGATGTGATGTCGGACGAAGAGATCGAGAGGATCAAGGAGATTGCTAAGCCCAAACTCGCA
CGAGCCACTGTGCGTGATCCCAAGACAGGTGTCCTCACTGTTGCTAGCTACAGAGTTTCCAAAA
GCTCCTGGCTAGAGGAAGACGATGACCCTGTTGTGGCCCGAGTCAACCGCAGGATGCAGCACAT
CACAGGGCTGACGGTGAAGACTGCAGAGCTATTGCAGGTCGCAAACTACGGAATGGGGGGACAG
TACGAACCACACTTTGACTTCTCGAGGAGCGATGAGCGAGATGCTTTCAAGCGTTTAGGGACTG
GGAACCGTGTGGCCACATTTCTAAACTACATGAGTGATGTTGAAGCTGGTGGCGCCACTGTCTT
CCCCGACTTGGGAGCTGCGATTTGGCCCAAGAAGGGCACGGCTGTATTTTGGTATAACCTTCTT
CGGAGCGGGGAAGGCGATTATCGAACGAGGCACGCGGCCTGCCCTGTGCTTGTGGGCTGCAAGT
GGGTCTCCAATAAGTGGTTCCATGAGCGAGGACAGGAGTTCTTGAGGCCTTGTGGGACAACGGA
AGTCGATTGACGTCCTTTTCTGCTCTGCCCCTCCCTGTCCCACAGTCCAAATCATCTTCAAGTT
CAGTGTGACAGCTTCCTTTGTATGTCCCAGCTCCTGTCAAGCAGGCCATTGGGGGAGCCAGTGT
TTGTCTGAATTGAGAGAGTGTGTCCTGAGCCGAGTCCTGGGTGACCTGGGCCGCAGGCTCTGGC
CAGCCTATGCCTGCCCTGGCTCCCAGGGTAGTCTTGTCATGGCTGTAGTAGAGCCAGACTGTAG
CACCCAGCACGGTGCCTTTGTACCTCAGATATTTCAGGTGGACGATGTTTCAGTGAAACCAAAG
TTCTGACACTGTTTACATGTTTGTTTTCTATGACATTTCTATTTGTTGTGGCTTTAACCAAAAA
ATAAAATAAAACAAAACAAAACAAAATAAAATGTTCCTGCCAGAAGCCTTAAAGAGCTTTA

hide sequence

RefSeq Acc Id:

XM_039086302 ⟹ XP_038942230

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,964 - 38,772,741 (+)	NCBI
mRatBN7.2	10	38,243,196 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

XM_063269331 ⟹ XP_063125401

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,743,964 - 38,772,741 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101745	(Get FASTA)	NCBI Sequence Viewer
	NP_001386468	(Get FASTA)	NCBI Sequence Viewer
	NP_001386469	(Get FASTA)	NCBI Sequence Viewer
	NP_001386470	(Get FASTA)	NCBI Sequence Viewer
	NP_001386471	(Get FASTA)	NCBI Sequence Viewer
	NP_001386472	(Get FASTA)	NCBI Sequence Viewer
	XP_008765913	(Get FASTA)	NCBI Sequence Viewer
	XP_017452859	(Get FASTA)	NCBI Sequence Viewer
	XP_038942230	(Get FASTA)	NCBI Sequence Viewer
	XP_063125401	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM04421	(Get FASTA)	NCBI Sequence Viewer
	EDM04422	(Get FASTA)	NCBI Sequence Viewer
	EDM04423	(Get FASTA)	NCBI Sequence Viewer
	EDM04424	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000070701.2
	ENSRNOP00000089755
	ENSRNOP00000089755.1
	ENSRNOP00000097385
	ENSRNOP00000097385.1

RefSeq Acc Id:	NP_001101745 ⟸ NM_001108275
- Peptide Label:	isoform 1 precursor
- UniProtKB:	A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLQVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASK MEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDED ESGAARALMRLQDTYKLDPDMISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQV LKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEE ERGKSLSNQTDAGLASQENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCRYHHGNRVP QLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKS SWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDERDAFKRLGTG NRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKW VSNKWFHERGQEFLRPCGTTEVD hide sequence

RefSeq Acc Id:	XP_008765913 ⟸ XM_008767691
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLQVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASK MEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDED ESGAARALMRLQDTYKLDPDMISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQV LKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEE ERGKSLSNQTDAGLASQENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCRYHHGNRVP QLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKS SWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDERDAFKRLGTG NRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKW VSNKWFHERGQEFLRPCGTTEVD hide sequence

RefSeq Acc Id:	XP_017452859 ⟸ XM_017597370
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLQVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASK MEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDED ESGAARALMRLQDTYKLDPDMISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQV LKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEE ERGKSLSNQTDAGLASQENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCRYHHGNRVP QLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKS SWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDERDAFKRLGTG NRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKW VSNKWFHERGQEFLRPCGTTEVD hide sequence

Ensembl Acc Id:

ENSRNOP00000070701 ⟸ ENSRNOT00000077185

Ensembl Acc Id:

ENSRNOP00000048172 ⟸ ENSRNOT00000042144

RefSeq Acc Id:	XP_038942230 ⟸ XM_039086302
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000089755 ⟸ ENSRNOT00000104075

Ensembl Acc Id:

ENSRNOP00000097385 ⟸ ENSRNOT00000106136

RefSeq Acc Id:	NP_001386472 ⟸ NM_001399543
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A0A8I6ACJ4 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386471 ⟸ NM_001399542
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A0A8I6ACJ4 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386469 ⟸ NM_001399540
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A0A8I6ACJ4 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386468 ⟸ NM_001399539
- Peptide Label:	isoform 1 precursor
- UniProtKB:	A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386470 ⟸ NM_001399541
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A0A8I6ACJ4 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125401 ⟸ XM_063269331
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6ACJ4 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

Protein Domains

Fe2OG dioxygenase Prolyl 4-hydroxylase alpha subunit

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZGT6-F1-model_v2	AlphaFold	D3ZGT6	1-535	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697193

Promoter ID:

EPDNEW_R7710

Type:

initiation region

Name:

P4ha2_1

Description:

prolyl 4-hydroxylase subunit alpha 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	39,435,287 - 39,435,347	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309673	AgrOrtholog
BioCyc Gene	G2FUF-25120	BioCyc
Ensembl Genes	ENSRNOG00000033663	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000077185.3	UniProtKB/TrEMBL
	ENSRNOT00000104075	ENTREZGENE
	ENSRNOT00000104075.2	UniProtKB/TrEMBL
	ENSRNOT00000106136	ENTREZGENE
	ENSRNOT00000106136.2	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/TrEMBL
	6.10.140.1460	UniProtKB/TrEMBL
	q2cbj1_9rhob like domain	UniProtKB/TrEMBL
InterPro	Oxoglutarate/Fe-dep_oxygenase	UniProtKB/TrEMBL
	P4HA-like	UniProtKB/TrEMBL
	Pro_4_hyd_alph	UniProtKB/TrEMBL
	Pro_4_hyd_alph_FE2OG_OXY	UniProtKB/TrEMBL
	Pro_4_hyd_alph_N	UniProtKB/TrEMBL
	TPR-like_helical	UniProtKB/TrEMBL
	TPR_repeat	UniProtKB/TrEMBL
KEGG Report	rno:360526	UniProtKB/TrEMBL
NCBI Gene	360526	ENTREZGENE
PANTHER	PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2	UniProtKB/TrEMBL
	PTHR10869	UniProtKB/TrEMBL
Pfam	2OG-FeII_Oxy_3	UniProtKB/TrEMBL
	P4Ha_N	UniProtKB/TrEMBL
	TPR_P4H	UniProtKB/TrEMBL
PhenoGen	P4ha2	PhenoGen
PROSITE	FE2OG_OXY	UniProtKB/TrEMBL
	TPR	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000033663	RatGTEx
SMART	P4Hc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48452	UniProtKB/TrEMBL
UniProt	A0A0G2JYL4_RAT	UniProtKB/TrEMBL
	A0A8I6ACJ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ASK1	ENTREZGENE, UniProtKB/TrEMBL
	A6HEG7	ENTREZGENE, UniProtKB/TrEMBL
	A6HEG8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-03	P4ha2	prolyl 4-hydroxylase subunit alpha 2	P4ha2	prolyl 4-hydroxylase, alpha polypeptide II	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-04-23	P4ha2	prolyl 4-hydroxylase, alpha polypeptide II	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	P4ha2_predicted	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	P4ha2_predicted	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide (predicted)			Symbol and Name status set to approved	70820	APPROVED

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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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