Gene: Kcng2 (potassium voltage-gated channel modifier subfamily G member 2) Rattus norvegicus
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Symbol:
Kcng2
Name:
potassium voltage-gated channel modifier subfamily G member 2
RGD ID:
1309521
Description:
Enables potassium channel regulator activity. Involved in regulation of potassium ion transport. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in membrane. Orthologous to human KCNG2 (potassium voltage-gated channel modifier subfamily G member 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
cardiac potassium channel subunit (Kv6.2); Kv6.2; LOC307234; potassium channel, voltage gated modifier subfamily G, member 2; potassium voltage-gated channel subfamily G member 2; potassium voltage-gated channel, subfamily G, member 2; voltage-gated potassium channel regulatory subunit KCNG2; voltage-gated potassium channel subunit Kv6.2
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Species
Gene symbol and name
Data Source
Assertion derived from
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Orthologs 1
Homo sapiens (human):
KCNG2 (potassium voltage-gated channel modifier subfamily G member 2)
HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):
Kcng2 (potassium voltage-gated channel, subfamily G, member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Kcng2 (potassium voltage-gated channel modifier subfamily G member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
KCNG2 (potassium voltage-gated channel modifier subfamily G member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
KCNG2 (potassium voltage-gated channel modifier subfamily G member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Kcng2 (potassium voltage-gated channel modifier subfamily G member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
KCNG2 (potassium voltage-gated channel modifier subfamily G member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
KCNG2 (potassium voltage-gated channel modifier subfamily G member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Kcng2 (potassium voltage-gated channel modifier subfamily G member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Kcng2 (potassium voltage-gated channel modifier subfamily G member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
PARP4 (poly(ADP-ribose) polymerase family member 4)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
KCNG2 (potassium voltage-gated channel modifier subfamily G member 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Kcng2 (potassium voltage-gated channel, subfamily G, member 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
kcng2 (potassium voltage-gated channel, subfamily G, member 2)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
C32C4.1
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Drosophila melanogaster (fruit fly):
Shab
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Caenorhabditis elegans (roundworm):
kvs-3
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Caenorhabditis elegans (roundworm):
kvs-4
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Xenopus tropicalis (tropical clawed frog):
kcng2
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
kcng2
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 18 76,017,225 - 76,085,377 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 18 76,018,047 - 76,083,688 (-) Ensembl GRCr8 mRatBN7.2 18 73,742,224 - 73,810,420 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 18 73,743,074 - 73,808,723 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 18 75,845,650 - 75,911,195 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 18 76,514,993 - 76,580,540 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 18 74,360,707 - 74,426,330 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 18 76,808,294 - 76,880,742 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 18 76,809,144 - 76,878,981 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 18 71,931,552 - 72,000,374 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 18 77,190,051 - 77,258,811 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 18 72,405,130 - 72,467,808 (-) NCBI Celera RGSC_v3.1 18 77,263,560 - 77,291,650 (-) NCBI Cytogenetic Map 18 q12.3 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Kcng2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Kcng2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcng2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Kcng2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcng2 Rat 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of KCNG2 mRNA CTD PMID:27291303 Kcng2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Kcng2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcng2 Rat 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO Kcng2 (Mus musculus) 6480464 2,3',4,4',5-pentachlorobiphenyl results in increased expression of KCNG2 mRNA CTD PMID:31388691 Kcng2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of KCNG2 mRNA CTD PMID:32109520 Kcng2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Kcng2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcng2 Rat 4,4'-sulfonyldiphenol increases expression ISO Kcng2 (Mus musculus) 6480464 bisphenol S results in increased expression of KCNG2 mRNA CTD PMID:39298647 Kcng2 Rat aflatoxin B1 decreases methylation ISO KCNG2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of KCNG2 gene CTD PMID:27153756 Kcng2 Rat all-trans-retinoic acid multiple interactions ISO Kcng2 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNG2 mRNA CTD PMID:36189433 Kcng2 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of KCNG2 mRNA CTD PMID:16483693 Kcng2 Rat arsane affects methylation ISO KCNG2 (Homo sapiens) 6480464 Arsenic affects the methylation of KCNG2 gene CTD PMID:25304211 Kcng2 Rat arsenic atom affects methylation ISO KCNG2 (Homo sapiens) 6480464 Arsenic affects the methylation of KCNG2 gene CTD PMID:25304211 Kcng2 Rat benzo[a]pyrene decreases methylation ISO KCNG2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of KCNG2 promoter CTD PMID:27901495 Kcng2 Rat benzo[a]pyrene decreases methylation ISO Kcng2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of KCNG2 intron CTD PMID:27901495 Kcng2 Rat bis(2-ethylhexyl) phthalate increases expression ISO KCNG2 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of KCNG2 mRNA CTD PMID:31163220 Kcng2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of KCNG2 mRNA CTD PMID:25181051 Kcng2 Rat bisphenol A affects methylation ISO KCNG2 (Homo sapiens) 6480464 bisphenol A affects the methylation of KCNG2 gene CTD PMID:31601247 Kcng2 Rat C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of KCNG2 mRNA CTD PMID:19167457 Kcng2 Rat cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of KCNG2 more ... CTD PMID:39012411 Kcng2 Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of KCNG2 mRNA CTD PMID:33453195 Kcng2 Rat cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of KCNG2 more ... CTD PMID:39012411 Kcng2 Rat CGP 52608 multiple interactions ISO KCNG2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to KCNG2 gene] CTD PMID:28238834 Kcng2 Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of KCNG2 mRNA CTD PMID:26577399 Kcng2 Rat cyclosporin A increases methylation ISO KCNG2 (Homo sapiens) 6480464 Cyclosporine results in increased methylation of KCNG2 promoter CTD PMID:27989131 Kcng2 Rat daidzein multiple interactions ISO KCNG2 (Homo sapiens) 6480464 [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA CTD PMID:16963248 Kcng2 Rat fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of KCNG2 mRNA CTD PMID:30307764 Kcng2 Rat formaldehyde increases expression ISO KCNG2 (Homo sapiens) 6480464 Formaldehyde results in increased expression of KCNG2 mRNA CTD PMID:27905399 Kcng2 Rat furan increases expression EXP 6480464 furan results in increased expression of KCNG2 mRNA CTD PMID:27387713 Kcng2 Rat genistein multiple interactions ISO KCNG2 (Homo sapiens) 6480464 [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA CTD PMID:16963248 Kcng2 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of KCNG2 mRNA CTD PMID:22061828 Kcng2 Rat glycitein multiple interactions ISO KCNG2 (Homo sapiens) 6480464 [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA CTD PMID:16963248 Kcng2 Rat Licochalcone B increases expression ISO KCNG2 (Homo sapiens) 6480464 licochalcone B results in increased expression of KCNG2 mRNA CTD PMID:33647349 Kcng2 Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of KCNG2 gene CTD PMID:35440735 Kcng2 Rat mono(2-ethylhexyl) phthalate decreases expression ISO Kcng2 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of KCNG2 mRNA CTD PMID:36189433 Kcng2 Rat mono(2-ethylhexyl) phthalate multiple interactions ISO Kcng2 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNG2 mRNA CTD PMID:36189433 Kcng2 Rat N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in increased methylation of KCNG2 gene CTD PMID:33148267 Kcng2 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO Kcng2 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KCNG2 mRNA CTD PMID:25566086 Kcng2 Rat PCB138 multiple interactions ISO Kcng2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcng2 Rat permethrin multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in increased methylation of KCNG2 gene CTD PMID:33148267 Kcng2 Rat resveratrol multiple interactions ISO KCNG2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of KCNG2 mRNA CTD PMID:23557933 Kcng2 Rat sodium arsenite decreases expression ISO Kcng2 (Mus musculus) 6480464 sodium arsenite results in decreased expression of KCNG2 mRNA CTD PMID:37682722 Kcng2 Rat sulforaphane increases expression ISO Kcng2 (Mus musculus) 6480464 sulforaphane results in increased expression of KCNG2 mRNA CTD PMID:30529165 Kcng2 Rat titanium dioxide decreases methylation ISO Kcng2 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of KCNG2 gene CTD PMID:35295148 Kcng2 Rat valproic acid increases methylation ISO KCNG2 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of KCNG2 gene CTD PMID:29154799