Ints6 (integrator complex subunit 6) - Rat Genome Database

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Gene: Ints6 (integrator complex subunit 6) Rattus norvegicus
Analyze
Symbol: Ints6
Name: integrator complex subunit 6
RGD ID: 1309480
Description: Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in RNA polymerase II transcription initiation surveillance; protein localization to chromatin; and snRNA 3'-end processing. Predicted to act upstream of or within transcription elongation by RNA polymerase II. Predicted to be located in actin cytoskeleton and nucleoplasm. Predicted to be part of INTAC complex and integrator complex. Predicted to be active in chromatin and nucleus. Orthologous to human INTS6 (integrator complex subunit 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ddx26; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26; LOC108352937; LOC361057; LRRGT00024; uncharacterized LOC108352937
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81541,080,584 - 41,224,350 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1541,109,125 - 41,197,519 (-)EnsemblGRCr8
mRatBN7.21536,908,966 - 37,048,043 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1536,933,724 - 37,021,527 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1538,799,204 - 38,868,188 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01539,950,048 - 40,019,034 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01538,393,782 - 38,462,771 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01545,844,050 - 45,929,996 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1545,858,608 - 45,947,030 (-)Ensemblrn6Rnor6.0
Rnor_5.01549,624,906 - 49,739,832 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41541,984,682 - 42,030,867 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1536,619,448 - 36,687,788 (-)NCBICelera
RGSC_v3.11541,941,623 - 42,027,088 (-)NCBI
Cytogenetic Map15p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP)
casticin  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
Diisodecyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
methapyrilene  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone enanthate  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA,ISO)
INTAC complex  (IEA,ISO)
integrator complex  (IBA,IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16239144   PMID:23904267  


Genomics

Comparative Map Data
Ints6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81541,080,584 - 41,224,350 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1541,109,125 - 41,197,519 (-)EnsemblGRCr8
mRatBN7.21536,908,966 - 37,048,043 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1536,933,724 - 37,021,527 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1538,799,204 - 38,868,188 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01539,950,048 - 40,019,034 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01538,393,782 - 38,462,771 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01545,844,050 - 45,929,996 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1545,858,608 - 45,947,030 (-)Ensemblrn6Rnor6.0
Rnor_5.01549,624,906 - 49,739,832 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41541,984,682 - 42,030,867 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1536,619,448 - 36,687,788 (-)NCBICelera
RGSC_v3.11541,941,623 - 42,027,088 (-)NCBI
Cytogenetic Map15p12NCBI
INTS6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381351,334,405 - 51,453,036 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1351,354,077 - 51,454,264 (-)Ensemblhg38GRCh38
GRCh371351,935,713 - 52,027,172 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361350,833,702 - 50,925,276 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341350,837,364 - 50,925,135NCBI
Celera1332,984,868 - 33,076,442 (-)NCBICelera
Cytogenetic Map13q14.3NCBI
HuRef1332,724,944 - 32,816,521 (-)NCBIHuRef
CHM1_11351,903,233 - 51,994,807 (-)NCBICHM1_1
T2T-CHM13v2.01350,555,225 - 50,667,956 (-)NCBIT2T-CHM13v2.0
Ints6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391462,913,774 - 62,998,617 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1462,913,779 - 62,998,618 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381462,676,325 - 62,761,163 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1462,676,330 - 62,761,169 (-)Ensemblmm10GRCm38
MGSCv371463,295,162 - 63,379,949 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361461,630,435 - 61,715,222 (-)NCBIMGSCv36mm8
Celera1460,435,077 - 60,519,880 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.23NCBI
Ints6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554314,728,533 - 4,809,494 (-)Ensembl
ChiLan1.0NW_0049554314,728,011 - 4,810,236 (-)NCBIChiLan1.0ChiLan1.0
INTS6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21452,788,177 - 52,886,749 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11351,432,185 - 51,530,680 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01332,487,169 - 32,583,415 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11351,233,645 - 51,328,618 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1351,242,452 - 51,327,882 (-)EnsemblpanPan2panpan1.1
INTS6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.122549,221 - 636,810 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl22549,179 - 636,523 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha22581,744 - 671,909 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.022529,584 - 620,164 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl22529,579 - 617,511 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.122451,170 - 541,417 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.022500,389 - 590,600 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.022518,661 - 608,887 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ints6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945160,714,609 - 160,798,393 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365654,199,195 - 4,282,443 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365654,198,659 - 4,282,443 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INTS6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1116,375,452 - 16,465,635 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11116,373,376 - 16,468,246 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21116,715,763 - 16,804,299 (+)NCBISscrofa10.2Sscrofa10.2susScr3
INTS6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1329,250,059 - 29,341,933 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl329,253,152 - 29,341,933 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605714,483,196 - 14,684,022 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ints6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247482,747,917 - 2,836,488 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247482,748,012 - 2,832,822 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ints6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11261,609,928 - 61,724,024 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ints6
709 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:34
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000035888
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat

Markers in Region
BF397819  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21536,940,276 - 36,940,466 (+)MAPPERmRatBN7.2
Rnor_6.01545,865,761 - 45,865,950NCBIRnor6.0
Rnor_5.01549,632,059 - 49,632,248UniSTSRnor5.0
RGSC_v3.41541,949,323 - 41,949,512UniSTSRGSC3.4
Celera1536,626,601 - 36,626,790UniSTS
RH 3.4 Map15211.7UniSTS
Cytogenetic Map15p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
19 13 79 209 91 90 59 142 59 6 456 264 22 187 106 117 31 33 33

Sequence


Ensembl Acc Id: ENSRNOT00000035888   ⟹   ENSRNOP00000034419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1545,901,196 - 45,947,030 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086271   ⟹   ENSRNOP00000074321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1541,109,125 - 41,178,114 (-)Ensembl
mRatBN7.2 Ensembl1536,933,724 - 37,021,527 (-)Ensembl
Rnor_6.0 Ensembl1545,858,608 - 45,927,804 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101257   ⟹   ENSRNOP00000095908
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1541,109,125 - 41,178,114 (-)Ensembl
mRatBN7.2 Ensembl1536,933,894 - 37,002,368 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109941   ⟹   ENSRNOP00000079529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1536,933,894 - 37,002,368 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000124714   ⟹   ENSRNOP00000100107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1541,151,573 - 41,197,519 (-)Ensembl
RefSeq Acc Id: NM_001271488   ⟹   NP_001258417
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,109,125 - 41,178,114 (-)NCBI
mRatBN7.21536,933,124 - 37,002,119 (-)NCBI
Rnor_6.01545,858,608 - 45,927,804 (-)NCBI
Rnor_5.01549,624,906 - 49,739,832 (-)NCBI
Celera1536,619,448 - 36,687,788 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003751499   ⟹   XP_003751547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,109,743 - 41,224,350 (-)NCBI
mRatBN7.21536,931,047 - 37,002,371 (-)NCBI
Rnor_6.01545,859,400 - 45,929,995 (-)NCBI
Rnor_5.01549,624,906 - 49,739,832 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093511   ⟹   XP_038949439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,109,743 - 41,224,350 (-)NCBI
mRatBN7.21536,933,742 - 37,048,043 (-)NCBI
RefSeq Acc Id: XM_063274422   ⟹   XP_063130492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,109,743 - 41,224,350 (-)NCBI
RefSeq Acc Id: XM_063274423   ⟹   XP_063130493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,109,743 - 41,224,350 (-)NCBI
RefSeq Acc Id: XM_063274424   ⟹   XP_063130494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,109,743 - 41,223,170 (-)NCBI
RefSeq Acc Id: XM_063274425   ⟹   XP_063130495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,109,743 - 41,224,298 (-)NCBI
RefSeq Acc Id: XM_063274426   ⟹   XP_063130496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,106,155 - 41,224,350 (-)NCBI
RefSeq Acc Id: XM_063274427   ⟹   XP_063130497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,098,797 - 41,224,350 (-)NCBI
RefSeq Acc Id: XM_063274428   ⟹   XP_063130498
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,106,155 - 41,224,350 (-)NCBI
RefSeq Acc Id: XR_005493766
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,080,584 - 41,224,350 (-)NCBI
mRatBN7.21536,908,966 - 37,002,371 (-)NCBI
RefSeq Acc Id: XP_003751547   ⟸   XM_003751499
- Peptide Label: isoform X2
- UniProtKB: A6K6E2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258417   ⟸   NM_001271488
- UniProtKB: A0A8I6AP01 (UniProtKB/TrEMBL),   A6K6E2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000034419   ⟸   ENSRNOT00000035888
Ensembl Acc Id: ENSRNOP00000074321   ⟸   ENSRNOT00000086271
RefSeq Acc Id: XP_038949439   ⟸   XM_039093511
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AP01 (UniProtKB/TrEMBL),   A6K6E2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095908   ⟸   ENSRNOT00000101257
Ensembl Acc Id: ENSRNOP00000079529   ⟸   ENSRNOT00000109941
RefSeq Acc Id: XP_063130497   ⟸   XM_063274427
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AP01 (UniProtKB/TrEMBL),   A6K6E2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130498   ⟸   XM_063274428
- Peptide Label: isoform X2
- UniProtKB: A6K6E2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130496   ⟸   XM_063274426
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AP01 (UniProtKB/TrEMBL),   A6K6E2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130493   ⟸   XM_063274423
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AP01 (UniProtKB/TrEMBL),   A6K6E2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130492   ⟸   XM_063274422
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AP01 (UniProtKB/TrEMBL),   A6K6E2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130495   ⟸   XM_063274425
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AP01 (UniProtKB/TrEMBL),   A6K6E2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130494   ⟸   XM_063274424
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AP01 (UniProtKB/TrEMBL),   A6K6E2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100107   ⟸   ENSRNOT00000124714
Protein Domains
Integrator complex subunit 6-like beta-barrel   INTS6/SAGE1/DDX26B/CT45 C-terminal   VWFA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7S2-F1-model_v2 AlphaFold A0A0G2K7S2 1-883 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309480 AgrOrtholog
BioCyc Gene G2FUF-13454 BioCyc
Ensembl Genes ENSRNOG00000009873 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000086271.3 UniProtKB/TrEMBL
  ENSRNOT00000101257 ENTREZGENE
  ENSRNOT00000101257.2 UniProtKB/TrEMBL
  ENSRNOT00000124714.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
InterPro Beta-barrel_INTS6 UniProtKB/TrEMBL
  INT_SG_DDX_CT_C UniProtKB/TrEMBL
  Integrator_subunit6 UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
KEGG Report rno:361057 UniProtKB/TrEMBL
NCBI Gene 361057 ENTREZGENE
PANTHER DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED UniProtKB/TrEMBL
  INTEGRATOR COMPLEX SUBUNIT 6 UniProtKB/TrEMBL
Pfam Beta-barrel_INTS6 UniProtKB/TrEMBL
  INT_SG_DDX_CT_C UniProtKB/TrEMBL
  VWA_2 UniProtKB/TrEMBL
PhenoGen Ints6 PhenoGen
PROSITE VWFA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009873 RatGTEx
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
UniProt A0A8I6AP01 ENTREZGENE, UniProtKB/TrEMBL
  A0ABZ3NN61_RAT UniProtKB/TrEMBL
  A6K6E2 ENTREZGENE, UniProtKB/TrEMBL
  Q6TXH5_RAT UniProtKB/TrEMBL
UniProt Secondary A0A0G2K7S2 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ints6  integrator complex subunit 6  LOC108352937  uncharacterized LOC108352937  Data merged from RGD:11414186 737654 PROVISIONAL
2016-08-02 LOC108352937  uncharacterized LOC108352937      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-03 Ints6  integrator complex subunit 6  Ddx26  DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ddx26  DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26  Ddx26_predicted  DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ddx26_predicted  DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26 (predicted)      Symbol and Name status set to approved 70820 APPROVED