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Gene: Sec24a (SEC24 homolog A, COPII component) Rattus norvegicus

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Symbol:

Sec24a

Name:

SEC24 homolog A, COPII component (Ensembl:SEC24 homolog A, COPII coat complex component)

RGD ID:

1309451

Description:

Predicted to enable SNARE binding activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading. Predicted to act upstream of or within cholesterol homeostasis; positive regulation of protein secretion; and regulation of cholesterol transport. Predicted to be located in ER to Golgi transport vesicle membrane; cytosol; and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Orthologous to human SEC24A (SEC24 homolog A, COPII coat complex component); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC103689920; LOC287275; protein transport protein Sec24A; SEC24 family member A; SEC24 family, member A; SEC24 family, member A (S. cerevisiae); SEC24 homolog A, COPII coat complex component; SEC24 related gene family, member A; SEC24 related gene family, member A (S. cerevisiae); uncharacterized LOC103689920

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SEC24A (SEC24 homolog A, COPII component)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Sec24a (SEC24 homolog A, COPII coat complex component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sec24a (SEC24 homolog A, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SEC24A (SEC24 homolog A, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SEC24A (SEC24 homolog A, COPII coat complex component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sec24a (SEC24 homolog A, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SEC24A (SEC24 homolog A, COPII coat complex component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SEC24A (SEC24 homolog A, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sec24a (SEC24 homolog A, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Sec24a (SEC24 homolog A, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SEC24B (SEC24 homolog B, COPII component)	HGNC	OrthoDB
Homo sapiens (human):	RAB5C (RAB5C, member RAS oncogene family)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SEC24A (SEC24 homolog A, COPII component)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sec24a (SEC24 homolog A, COPII coat complex component)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sec24a (SEC24 homolog A, COPII coat complex component)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	sec-24.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SEC24	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SFB2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Sec24AB	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sec24a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sec24a	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	36,450,043 - 36,525,303 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	36,450,043 - 36,525,303 (-)	Ensembl				GRCr8
mRatBN7.2	10	35,946,901 - 36,024,353 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	35,947,031 - 36,024,353 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	40,642,849 - 40,718,575 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	40,132,834 - 40,208,555 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	35,636,547 - 35,712,284 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	37,138,539 - 37,215,899 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	37,139,806 - 37,215,899 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	34,817,549 - 34,826,602 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	10	36,911,427 - 36,988,825 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	37,208,603 - 37,283,895 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	35,304,430 - 35,379,024 (-)	NCBI		Celera
RGSC_v3.1	10	37,215,390 - 37,284,473 (-)	NCBI
Cytogenetic Map	10	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

progressive muscular atrophy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-palmitoylglycerol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

cadmium dichloride (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

DDE (ISO)

deoxynivalenol (ISO)

dibutyl phthalate (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethyl methanesulfonate (ISO)

fluoranthene (ISO)

folic acid (ISO)

gentamycin (EXP)

gold atom (ISO)

gold(0) (ISO)

ivermectin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methamphetamine (EXP)

methapyrilene (EXP,ISO)

methyl methanesulfonate (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

rotenone (ISO)

sodium arsenite (ISO)

thioacetamide (EXP)

thiram (ISO)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cholesterol homeostasis (ISO)

COPII-coated vesicle cargo loading (IBA,ISO)

endoplasmic reticulum to Golgi vesicle-mediated transport (IEA,ISO)

intracellular protein transport (IEA)

positive regulation of protein secretion (ISO)

protein transport (IEA)

regulation of cholesterol transport (ISO)

vesicle-mediated transport (IEA)

Cellular Component

COPII vesicle coat (IBA,IEA,ISO)

cytoplasmic vesicle (IEA)

cytosol (IEA)

endoplasmic reticulum exit site (IBA)

endoplasmic reticulum membrane (IEA)

ER to Golgi transport vesicle membrane (IEA)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

SNARE binding (IBA)

zinc ion binding (IBA,IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Endoplasmic Reticulum-associated degradation pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:17499046	PMID:18843296	PMID:20427317	PMID:23580231

Genomics

Comparative Map Data

Sec24a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	36,450,043 - 36,525,303 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	36,450,043 - 36,525,303 (-)	Ensembl				GRCr8
mRatBN7.2	10	35,946,901 - 36,024,353 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	35,947,031 - 36,024,353 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	40,642,849 - 40,718,575 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	40,132,834 - 40,208,555 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	35,636,547 - 35,712,284 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	37,138,539 - 37,215,899 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	37,139,806 - 37,215,899 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	34,817,549 - 34,826,602 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	10	36,911,427 - 36,988,825 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	37,208,603 - 37,283,895 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	35,304,430 - 35,379,024 (-)	NCBI		Celera
RGSC_v3.1	10	37,215,390 - 37,284,473 (-)	NCBI
Cytogenetic Map	10	q22	NCBI

SEC24A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	134,648,382 - 134,727,909 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	134,648,588 - 134,727,909 (+)	Ensembl			hg38	GRCh38
GRCh37	5	133,984,475 - 134,063,599 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	134,012,378 - 134,091,500 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	134,012,709 - 134,091,398	NCBI
Celera	5	130,110,657 - 130,189,971 (+)	NCBI		Celera
Cytogenetic Map	5	q31.1	NCBI
HuRef	5	129,170,647 - 129,249,607 (+)	NCBI		HuRef
CHM1_1	5	133,417,069 - 133,496,225 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	135,172,809 - 135,253,535 (+)	NCBI		T2T-CHM13v2.0

Sec24a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	51,583,090 - 51,649,172 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	51,583,091 - 51,654,461 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	51,692,263 - 51,757,161 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	51,692,264 - 51,763,634 (-)	Ensembl			mm10	GRCm38
MGSCv37	11	51,505,765 - 51,570,336 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	51,538,243 - 51,600,008 (-)	NCBI		MGSCv36	mm8
Celera	11	56,259,252 - 56,323,967 (-)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	31.28	NCBI

Sec24a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	5,803,455 - 5,848,093 (+)	Ensembl
ChiLan1.0	NW_004955408	5,803,438 - 5,850,879 (+)	NCBI	ChiLan1.0	ChiLan1.0

SEC24A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	129,945,473 - 130,023,324 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	128,085,052 - 128,162,886 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	130,050,625 - 130,128,212 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	136,197,495 - 136,273,158 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	136,197,746 - 136,273,158 (+)	Ensembl			panPan2	panpan1.1

SEC24A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	22,749,633 - 22,813,045 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	22,750,046 - 22,810,199 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	21,499,013 - 21,562,145 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	23,555,714 - 23,619,270 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	23,555,703 - 23,619,248 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	22,254,959 - 22,318,573 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	22,121,201 - 22,184,878 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	22,763,524 - 22,826,917 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Sec24a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	113,607,154 - 113,686,258 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936647	612,976 - 688,552 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936647	612,640 - 689,963 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SEC24A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	136,883,854 - 136,952,178 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	136,833,399 - 136,952,181 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	142,447,631 - 142,565,796 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SEC24A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	37,448,344 - 37,501,745 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666034	40,396,807 - 40,476,728 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sec24a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	37,620,211 - 37,693,636 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624733	37,620,326 - 37,693,753 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Sec24a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	34,274,642 - 34,345,680 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Sec24a
659 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	301
Count of miRNA genes:	200
Interacting mature miRNAs:	223
Transcripts:	ENSRNOT00000006356
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35893451	64140567	Rat
152025229	Scl83	Serum cholesterol level QTL 83	4.33		blood cholesterol amount (VT:0000180)		10	36211556	69161158	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31796281	76796281	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15776754	60776754	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	27023535	98502431	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	27443787	72443787	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	35509383	91417879	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	19939207	64939207	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	18035782	63035782	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18668419	63668419	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21833758	61843633	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28950353	73950353	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35893263	64653589	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29800910	64653589	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	27443787	72443787	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22931373	91127454	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
634329	Pia15	Pristane induced arthritis QTL 15	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	24662123	73695339	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	27023535	61843633	Rat
2298480	Eau7	Experimental allergic uveoretinitis QTL 7		0.0049	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	35509383	80509383	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29800910	91417879	Rat
2298495	Eae23	Experimental allergic encephalomyelitis QTL 23	16.93		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	10	16175525	61175525	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	20110614	65110614	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat
1354614	Hpcl1	Hepatic cholesterol level QTL 1	3.3		liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	35893263	52293000	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	27587226	96099902	Rat
2289985	Bp305	Blood pressure QTL 305			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	29076978	74076978	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	18035782	63035782	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	27443787	72443787	Rat
1600371	Mcs21	Mammary carcinoma susceptibility QTL 21	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	29377046	52699134	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31129113	76129113	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	35509383	88177745	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	20110614	65110614	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	27023535	99451848	Rat

Markers in Region

D10Arb18

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	35,987,481 - 35,987,588 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	37,179,147 - 37,179,253	NCBI	Rnor6.0
Rnor_5.0	10	36,952,001 - 36,952,107	UniSTS	Rnor5.0
RGSC_v3.4	10	37,246,992 - 37,247,099	RGD	RGSC3.4
RGSC_v3.4	10	37,246,993 - 37,247,099	UniSTS	RGSC3.4
Celera	10	35,342,010 - 35,342,116	UniSTS
RGSC_v3.1	10	37,253,422 - 37,253,529	RGD
Cytogenetic Map	10	q22	UniSTS

AI180289

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	35,948,889 - 35,949,023 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	37,140,528 - 37,140,661	NCBI	Rnor6.0
Rnor_6.0	10	35,046,839 - 35,046,972	NCBI	Rnor6.0
Rnor_5.0	10	36,913,416 - 36,913,549	UniSTS	Rnor5.0
Rnor_5.0	10	34,819,538 - 34,819,671	UniSTS	Rnor5.0
RGSC_v3.4	10	37,208,408 - 37,208,541	UniSTS	RGSC3.4
Celera	10	35,304,235 - 35,304,368	UniSTS
RH 3.4 Map	10	387.21	UniSTS
Cytogenetic Map	10	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105780	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC096219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC105470	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC110466	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006356 ⟹ ENSRNOP00000006356

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	36,450,043 - 36,525,303 (-)	Ensembl
mRatBN7.2 Ensembl	10	35,949,085 - 36,024,353 (-)	Ensembl
Rnor_6.0 Ensembl	10	37,140,723 - 37,215,899 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084136

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	10	35,044,234 - 35,054,225 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000090459

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	10	35,044,234 - 35,054,225 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000090475 ⟹ ENSRNOP00000069364

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	36,450,043 - 36,525,303 (-)	Ensembl
mRatBN7.2 Ensembl	10	35,947,031 - 36,018,377 (-)	Ensembl
Rnor_6.0 Ensembl	10	37,139,806 - 37,209,881 (-)	Ensembl

RefSeq Acc Id:

NM_001105780 ⟹ NP_001099250

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,450,043 - 36,525,303 (-)	NCBI
mRatBN7.2	10	35,949,085 - 36,024,353 (-)	NCBI
Rnor_6.0	10	37,140,723 - 37,215,899 (-)	NCBI
Rnor_5.0	10	36,911,427 - 36,988,825 (-)	NCBI
RGSC_v3.4	10	37,208,603 - 37,283,895 (-)	RGD
Celera	10	35,304,430 - 35,379,024 (-)	NCBI

Sequence:

show sequence

GCCCTCAGTTCCGCCTCCTTGCGGTCTTGCCACCAATCACTGTGCCCCGGACCATTTCACGCCA
ACCCCAAGAGCATCCGCTGAGCCACCAGCGGAAGATGATGACATCGGTCGTTTCAGGTAATCCT
CAAAGATTCCCGGAAGAGGAGCCCGGTTTCTCCTATCCCACCCGATCGACTCTAAAAGTCCGCA
CCACCCTCAGATCCCCGGTCTGTCAAGAAGGTGACGTTCTCCATGCCGGGGATTTTCGTAGTGG
TGACACAGGCTACTTCCGGCGGGCGGCGGGAGTCAGTGACGTGGCAGGCGAGTCTGTGCACGGT
CCTCCCGGCCAGGACACGGGACTGTCAGCTGGCCTCGGGGCAGCTCCCCGGGACAGAGAGCACG
GCCGCAGCCTCCAGCCGGAACCGGAAGTGCCACGTGTCCCCACTGTGCCTGCGCGGCCGGCGGC
TCCGCCCAGGGCCTCCCTCCTCTCCGGGTTCGGCTGCCGCCTCCGAGCCCGGCGTTCGCAGCCC
CGCCGGCCTGACTCCGGAGCCTCTCCGAGCCCAGGCCGGGTCGTGGCCGCCGGCGGGCTGAAGA
GACCGAGACGCCATGCCTCGACTTTGACGCGCCACCCCCGCGTGTTCCGCTTCTCCAGTTTCAG
CTCCCTTCCCTCGGCTTTCCTGTTGGAGCTCTTAGGATCGGCGCTGCGGTCGACCCCGACGGCT
CTGTCCTACCCTGAGATCCCCGGGCGCCATGGCCCAGCCCAGGATCCCGGCTGCCCGCGGCGCC
GCAGCCGGCCTCCAGGCCCAGAACGGAGCCGCCTCAGCCTCGGGGTCTCCCTACACCAACGGTC
CTGTCCAACATACACTGATGTCTTCACAAGTATCACTGAGCCAAGGATATGATTCCCAACTTCC
AGGATCCTACCCTCATCCAATGCCAGCAAAGACTTTGAATCCATTCTCTGCACAGTCGAACTAT
GGTGGTTCTCAGGGATCTGGACAGGCTCTTAATAGTCCACTTGTGACTTCCAGTCCAGTACCAC
CCTCACTTCATAGTGGTCCTGTTCCCCGAATGGCACTACCTACTTCTCAGAACCCAGCTGCTAC
ACCAATGCCTTCTGGTAGCTTTCCTCCTGGAACCAACCCCGCCCCGCCTCTGAATTGGCAATAT
AACCATCCATCCACAGGACCACAGACCAATCATTTTCCTCATGTAGCTCAGCCAACTATACCTG
GGAATACAGATTTCACAGCAGATCATCCGTATGTTTCTTCTGGAGACCCTGCACTTCAAACCAG
CTTCAAAAAGCCAGGTTCTGCACTTCCCTTACAGAATCCACCTCTGCCTCCCACTTTTCAGCCA
GGAGCCCCTCCTGGGCCTCCTCCAGCTGGAGGCCCGCCTCCCAGCCGGGGCCCTGTGCCCCAGA
AAACACCTCCTAGGGCTGCGTTCCCACCCTCACTTAACTCAGCTGTCAATCAAGAAGGTATTAC
ATCAAATGCCAATACCGGATCTGCGGCTCACAGCACTTACGATGAAATTGAAGGAGGTGGCTTC
TTGGCAACACCACAGCTTGTTAATCAGAACCCCAAAACAAGCCGAAGTGTGGGATATGCATACC
CCTCCCTACCACCAGGCTACCAGAACACCGCACCACCAGTGGCTGGAATGCCACCCTCCTCCCT
GAATTACCCAAGTGGTCCCCAGGCCTTTACTCAGGCTCCCTTAGGTGCTAATCATTTAACTGCG
AGCATGAGTGGATTAAGTCTACATCCAGAGGGTCTAAGAGTTGTCAATCTTCTTCAAGAAAGGA
ATATGCTTCCTTCGACACCATTGCAGCCTCCAGTCCCAAACTTGCTTGAAGACGTCCAGAAACT
CAACTGTAACCCAGAGTTATTTCGCTGCACACTGACTAGTGTCCCTCAGACTCAGGCCTTACTG
AATAAAGCCAAGCTTCCTTTGGGGCTGCTGCTCCACCCTTTCAAGGACCTAGTGCAGTTGCCCG
TAGTCACCTCCAGTACAATTGTGAGATGCCGGTCATGCAGGACCTACATCAACCCCTTTGTCAA
CTTTCTGGATCAAAGAAGGTGGAAATGTAACTTATGTTATCGAGTCAATGATGTTCCTGAAGAA
TTCATGTACAATCCTTTAACCAGAGTTTATGGTGAACCTCACAAAAGACCTGAAGTCCAGAATG
CTACTATTGAGTTTATGGCTCCTTCAGAGTACATGTTACGACCACCACAACCTCCAGTGTACCT
CTTTGTATTTGACGTATCTCACAACGCAATAGAAACTGGATACTTGAATTCAGTTTGCCAGAGT
TTGTTAGACAATCTGGATCTGCTTCCTGGCAACACTAGGACGAAGATCGGTTTCATAACGTTTG
ATAGCACTATCCATTTCTACAGCCTTCAGGAAGGTCTCTCCCAGCCTCAGATGCTAATAGTTTC
AGATATTGACGATGTTTTTATACCGATGCCAGAGAACTTACTAGTAAACTTAAATGAAAGTAAA
GAGCTTGTCCAAGATTTACTGAAAACGTTACCGCAAATGTTTACTAAGACGCTGGAGACCCAGA
GCGCCTTGGGTCCTGCACTTCAGGCTGCATTTAAGCTGATATCACCAACTGGTGGTCGAATGTC
TGTCTTCCAAACACAACTCCCAACGCTTGGTGTCGGAGCCCTGAAACCACGAGAGGAACCCAAC
CAAAGGTCATCTGCTAAGGAAATACACCTGACACCATCCACTGACTTCTATAAGAAGTTAGCCT
TGGACTGCTCTGGGCAGCAGGCAGCCGTAGACCTATTCCTTCTCAGTGGACAGTATTCCGATTT
GGCTTCTCTAGGCTGTATCTCTCGGTACTCAGCAGGCAGTGTGTATTACTATCCCTCGTACCAC
CATCAGCACAATCCAGTGCAAGTTCAGAAATTCCAGAAGGAACTCCACAGGTACCTTACTCGCA
AGATTGGATTTGAGGCAGTCATGAGGATCCGGTGCACCAAAGGTCTTTCCATCCATACTTTCCA
TGGAAACTTCTTCGTCCGTTCTACAGACTTACTGTCTCTTCCCAACGTAAACCCGGATGCTGGG
TACGCAGTACAGATGTCCGTAGAAGAGAGCCTCACCGACACGCAGCTGGTTTCCTTTCAGTCAG
CACTCTTATATACATCGAGTAAAGGTGAAAGAAGAATCCGAGTCCATACTTTGTGTTTGCCTGT
AGTCTCTACCCTGAATGAAGTCTTTCTTGGAGCTGATGTGCAAGCAATTTCAGGGTTATTGGCC
AATATGGCTGTTGATAGGTCAGTGACTGCCAGCCTAAGTGATGCCCGGGATGCTCTGGTGAACG
CTGTCATAGACTCTCTCTCAGCTTACCGCTCTTCAGTCCTGAGTAGCCAGCAGCCAGGCCTCAT
GGTTCCTTTCTCCTTGAGGCTTTTCCCACTTTTTGTGTTGGCTCTCCTTAAACAGAAATCTTTC
CAGACTGGGACAAATGTACGTCTAGATGAACGAATTTTTGCCATGTGTCAAGTGAAAAACCAGC
CGTTGGTTCACCTCATGCTCACAACGCACCCCAGTTTGTACAGAGTTGACAACCTCTCAGATGA
GGGAGCTCTCAACATCAATGACAGAACCATACCTCAGCCCCCCATTCTTCAGCTGTCGGTGGAG
AAGTTGAGCAGAGATGGAGCGTTCCTCATGGATGCAGGCTCAGTACTGATGCTTTGGGTTGGAA
GAAATTGTGCACAGAATTTTCTCAGCCAAGTTCTGGGAGTTCAAAACTATGCATCAATTCCACA
GACAATGACAGACCTTCCAGAACTTGATACACCAGAATCTGCCAGAATGACAGCTTTTATCTCC
TGGCTTAGAGAACAGAGGCCATTTTTCCCAATACTCTATGTAATCAGAGAGGAGAGTCTGATGA
AGGCAGCCTTCCTTCAGAACCTGGTAGAAGACAGAACGGAGTCAGCGCTGTCATATTATGAATT
CCTCCTGCACATACAGCAGCAAGTGAACAAGTGACGAGTCGTGGGCTGCTGAGGAACCACTTTC
AGAGTTCCTGGGGATACAGTACCTTCCTTTCCTCCTTAAAATTGTGAACAAATGTGATGATGAT
TACGATGTTTCACTGTGATTTTAACCAACTATAGCAAATAAAGGACCACAGCTGAGGGTCAGAC
GTGCAACTCCAAAATACTGTATTTTTCAAATCAAAATAGATGTCTACACGATTGGAAACCTTTT
TTTCCCCTTTGCTGCCAACTATGTTTGAGTTGTTATGGATTGAAATGAGACAATATTGCAGAGG
CAAAGTACATTTTATAAAATAAAGACTTCTGTGTTCTGCATTTCTATTTCTCATTTTTTTTTAT
TAGTTTTTGGCTGCTACATTTAAAAAACCTCACAAGACTACGTGTTGCAGGGAGTTTCAAGTCT
ATCAATAATGATCTTTTTCAAATTGGGAAATCCAAAAGTCAACAGACTGTAGAAAAGCTGGAAT
CCATTCCCTTTACATGTTTGGTTTTTGCCCCACCCCCCACCTTTTTTTAAGGAAGGCAAAAGAT
CATGTTAACTAAAGTTGGAGTAAGCCAGCTCTGGTCCTGCTTGGGAAGAACATAAAGTAACTGT
CAAGCTTTAAAGTCTGTCAGTATTTTCTCTACTTGAACAAAGTCACTTTAATTTGAGGTGAAAA
CTAATTAGGTGGT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099250	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM04330	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006356
	ENSRNOP00000006356.5
	ENSRNOP00000069364.3

RefSeq Acc Id:

NP_001099250 ⟸ NM_001105780

- UniProtKB:

D3ZZA8 (UniProtKB/TrEMBL), A6HE75 (UniProtKB/TrEMBL), A0A0G2JV63 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAQPRIPAARGAAAGLQAQNGAASASGSPYTNGPVQHTLMSSQVSLSQGYDSQLPGSYPHPMPA
KTLNPFSAQSNYGGSQGSGQALNSPLVTSSPVPPSLHSGPVPRMALPTSQNPAATPMPSGSFPP
GTNPAPPLNWQYNHPSTGPQTNHFPHVAQPTIPGNTDFTADHPYVSSGDPALQTSFKKPGSALP
LQNPPLPPTFQPGAPPGPPPAGGPPPSRGPVPQKTPPRAAFPPSLNSAVNQEGITSNANTGSAA
HSTYDEIEGGGFLATPQLVNQNPKTSRSVGYAYPSLPPGYQNTAPPVAGMPPSSLNYPSGPQAF
TQAPLGANHLTASMSGLSLHPEGLRVVNLLQERNMLPSTPLQPPVPNLLEDVQKLNCNPELFRC
TLTSVPQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCRSCRTYINPFVNFLDQRRWKC
NLCYRVNDVPEEFMYNPLTRVYGEPHKRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNA
IETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYSLQEGLSQPQMLIVSDIDDVFIPM
PENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLISPTGGRMSVFQTQLPTL
GVGALKPREEPNQRSSAKEIHLTPSTDFYKKLALDCSGQQAAVDLFLLSGQYSDLASLGCISRY
SAGSVYYYPSYHHQHNPVQVQKFQKELHRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTD
LLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNEVFL
GADVQAISGLLANMAVDRSVTASLSDARDALVNAVIDSLSAYRSSVLSSQQPGLMVPFSLRLFP
LFVLALLKQKSFQTGTNVRLDERIFAMCQVKNQPLVHLMLTTHPSLYRVDNLSDEGALNINDRT
IPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGRNCAQNFLSQVLGVQNYASIPQTMTDLPELD
TPESARMTAFISWLREQRPFFPILYVIREESLMKAAFLQNLVEDRTESALSYYEFLLHIQQQVN
K

hide sequence

Ensembl Acc Id:

ENSRNOP00000006356 ⟸ ENSRNOT00000006356

Ensembl Acc Id:

ENSRNOP00000069364 ⟸ ENSRNOT00000090475

Protein Domains

Gelsolin-like Sec23/Sec24 beta-sandwich Sec23/Sec24 helical Sec23/Sec24 trunk Zinc finger Sec23/Sec24-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZZA8-F1-model_v2	AlphaFold	D3ZZA8	1-1089	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697165

Promoter ID:

EPDNEW_R7689

Type:

initiation region

Name:

Sec24a_1

Description:

SEC24 homolog A, COPII coat complex component

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	37,209,876 - 37,209,936	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309451	AgrOrtholog
BioCyc Gene	G2FUF-25189	BioCyc
Ensembl Genes	ENSRNOG00000004563	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000056265	Ensembl
Ensembl Transcript	ENSRNOT00000006356	ENTREZGENE
	ENSRNOT00000006356.7	UniProtKB/TrEMBL
	ENSRNOT00000090475.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.20.10	UniProtKB/TrEMBL
	3.40.50.410	UniProtKB/TrEMBL
	beta-sandwich domain of Sec23/24	UniProtKB/TrEMBL
	Sec23/Sec24 helical domain	UniProtKB/TrEMBL
	Zn-finger domain of Sec23/24	UniProtKB/TrEMBL
InterPro	ADF-H/Gelsolin-like_dom	UniProtKB/TrEMBL
	Gelsolin-like_dom_sf	UniProtKB/TrEMBL
	Gelsolin_dom	UniProtKB/TrEMBL
	Sec23/24_helical_dom	UniProtKB/TrEMBL
	Sec23/24_helical_dom_sf	UniProtKB/TrEMBL
	Sec23/24_trunk_dom	UniProtKB/TrEMBL
	Sec23_24_beta_S	UniProtKB/TrEMBL
	SEC23_SEC24_subfamily	UniProtKB/TrEMBL
	Sec24-like_trunk_dom	UniProtKB/TrEMBL
	vWFA_dom_sf	UniProtKB/TrEMBL
	Znf_Sec23_Sec24	UniProtKB/TrEMBL
	Znf_Sec23_Sec24_sf	UniProtKB/TrEMBL
KEGG Report	rno:287275	UniProtKB/TrEMBL
NCBI Gene	287275	ENTREZGENE
PANTHER	PROTEIN TRANSPORT PROTEIN SEC24A	UniProtKB/TrEMBL
	SEC24-RELATED PROTEIN	UniProtKB/TrEMBL
Pfam	Gelsolin	UniProtKB/TrEMBL
	Sec23_BS	UniProtKB/TrEMBL
	Sec23_helical	UniProtKB/TrEMBL
	Sec23_trunk	UniProtKB/TrEMBL
	zf-Sec23_Sec24	UniProtKB/TrEMBL
PhenoGen	Sec24a	PhenoGen
RatGTEx	ENSRNOG00000004563	RatGTEx
	ENSRNOG00000056265	RatGTEx
Superfamily-SCOP	beta-sandwich domain of Sec23/24	UniProtKB/TrEMBL
	Sec23_helical	UniProtKB/TrEMBL
	SSF53300	UniProtKB/TrEMBL
	SSF82754	UniProtKB/TrEMBL
	SSF82919	UniProtKB/TrEMBL
UniProt	A0A0G2JV63	ENTREZGENE, UniProtKB/TrEMBL
	A6HE75	ENTREZGENE, UniProtKB/TrEMBL
	D3ZZA8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2025-11-13	Sec24a	SEC24 homolog A, COPII component	Sec24a	SEC24 homolog A, COPII coat complex component	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2021-03-09	Sec24a	SEC24 homolog A, COPII coat complex component	LOC103689920	uncharacterized LOC103689920	Data merged from RGD:9221572	737654	PROVISIONAL
2015-08-13	Sec24a	SEC24 homolog A, COPII coat complex component	Sec24a	SEC24 family member A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-08-25	LOC103689920	uncharacterized LOC103689920			Symbol and Name status set to provisional	70820	PROVISIONAL
2013-11-11	Sec24a	SEC24 family member A	Sec24a	SEC24 family, member A (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-20	Sec24a	SEC24 family, member A (S. cerevisiae)	Sec24a	SEC24 related gene family, member A (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Sec24a	SEC24 related gene family, member A (S. cerevisiae)	Sec24a_predicted	SEC24 related gene family, member A (S. cerevisiae) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Sec24a_predicted	SEC24 related gene family, member A (S. cerevisiae) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)