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Gene: Irgq (immunity-related GTPase Q) Rattus norvegicus

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Symbol:

Irgq

Name:

immunity-related GTPase Q

RGD ID:

1309409

Description:

Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in positive regulation of autophagy; protein quality control for misfolded or incompletely synthesized proteins; and substrate localization to autophagosome. Predicted to be active in autophagosome and lysosome. Orthologous to human IRGQ (immunity related GTPase Q); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

immunity-related GTPase family, Q; LOC292708; RGD1309409; similar to FKSG27

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IRGQ (immunity related GTPase Q)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Irgq (immunity-related GTPase family, Q)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Irgq (immunity related GTPase Q)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IRGQ (immunity related GTPase Q)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IRGQ (immunity related GTPase Q)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Irgq (immunity related GTPase Q)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IRGQ (immunity related GTPase Q)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IRGQ (immunity related GTPase Q)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Irgq (immunity related GTPase Q)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Irgq (immunity related GTPase Q)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	IRGQ (immunity related GTPase Q)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Irgq (immunity-related GTPase family, Q)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	irgq2 (immunity-related GTPase family, q2)	Alliance	DIOPT (OMA\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	89,251,846 - 89,259,799 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	89,239,205 - 89,259,799 (+)	Ensembl				GRCr8
mRatBN7.2	1	80,123,925 - 80,131,881 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	80,123,925 - 80,131,881 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	85,517,541 - 85,525,491 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	94,067,378 - 94,075,331 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	87,273,366 - 87,281,317 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	81,395,922 - 81,403,872 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	81,395,841 - 81,399,672 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	82,656,242 - 82,664,190 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	79,816,826 - 79,824,777 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	74,576,973 - 74,584,923 (+)	NCBI		Celera
RGSC_v3.1	1	79,893,608 - 79,902,886 (+)	NCBI
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

acrylamide (ISO)

actinomycin D (ISO)

aflatoxin B1 (EXP,ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

dimethylselenide (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

ivermectin (ISO)

lead(0) (ISO)

leflunomide (ISO)

Nutlin-3 (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

reactive oxygen species (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

torcetrapib (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of autophagy (ISO)

protein quality control for misfolded or incompletely synthesized proteins (ISO)

substrate localization to autophagosome (ISO)

Cellular Component

autophagosome (ISO)

lysosome (ISO)

Molecular Function

GTP binding (IEA,ISO)

GTPase activity (ISO)

protein binding (ISO)

protein-macromolecule adaptor activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:28131823

Genomics

Comparative Map Data

Irgq
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	89,251,846 - 89,259,799 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	89,239,205 - 89,259,799 (+)	Ensembl				GRCr8
mRatBN7.2	1	80,123,925 - 80,131,881 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	80,123,925 - 80,131,881 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	85,517,541 - 85,525,491 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	94,067,378 - 94,075,331 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	87,273,366 - 87,281,317 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	81,395,922 - 81,403,872 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	81,395,841 - 81,399,672 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	82,656,242 - 82,664,190 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	79,816,826 - 79,824,777 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	74,576,973 - 74,584,923 (+)	NCBI		Celera
RGSC_v3.1	1	79,893,608 - 79,902,886 (+)	NCBI
Cytogenetic Map	1	q21	NCBI

IRGQ
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	43,584,367 - 43,596,134 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	43,584,367 - 43,596,145 (-)	Ensembl			hg38	GRCh38
GRCh37	19	44,088,519 - 44,100,286 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	48,787,866 - 48,791,516 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	40,890,998 - 40,902,768 (-)	NCBI		Celera
Cytogenetic Map	19	q13.31	NCBI
HuRef	19	40,519,278 - 40,531,046 (-)	NCBI		HuRef
CHM1_1	19	44,090,267 - 44,102,035 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	46,406,008 - 46,417,777 (-)	NCBI		T2T-CHM13v2.0

Irgq
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	24,230,073 - 24,238,025 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	24,230,114 - 24,238,025 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	24,530,648 - 24,538,600 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	24,530,689 - 24,538,600 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	25,315,667 - 25,323,619 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	24,239,449 - 24,247,360 (+)	NCBI		MGSCv36	mm8
Celera	7	19,144,746 - 19,152,698 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	11.32	NCBI

Irgq
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955555	1,329,812 - 1,334,317 (-)	Ensembl
ChiLan1.0	NW_004955555	1,328,187 - 1,335,018 (-)	NCBI	ChiLan1.0	ChiLan1.0

IRGQ
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	49,744,895 - 49,755,300 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	51,613,857 - 51,624,292 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	40,533,711 - 40,538,157 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	49,141,775 - 49,146,061 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	49,141,775 - 49,146,061 (-)	Ensembl			panPan2	panpan1.1

IRGQ
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	111,532,975 - 111,540,585 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	111,532,317 - 111,537,042 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	111,012,412 - 111,020,311 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	112,142,811 - 112,150,712 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	112,143,862 - 112,149,648 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	111,730,931 - 111,738,826 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	111,364,761 - 111,372,662 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	112,249,011 - 112,256,913 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Irgq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	16,443,535 - 16,451,766 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936706	790,963 - 798,969 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936706	790,878 - 799,100 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IRGQ
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	50,433,862 - 50,445,575 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	50,433,858 - 50,442,106 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	46,188,729 - 46,206,689 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IRGQ
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	37,111,782 - 37,116,258 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	37,112,015 - 37,115,322 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	16,654,203 - 16,658,672 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Irgq
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624907	1,125,465 - 1,129,088 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624907	1,121,208 - 1,129,714 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Irgq
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	170,178,103 - 170,182,490 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Irgq
50 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	861
Count of miRNA genes:	320
Interacting mature miRNAs:	440
Transcripts:	ENSRNOT00000072750
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	51909206	91302615	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat

Markers in Region

RH138812

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	80,128,968 - 80,129,100 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	81,400,960 - 81,401,091	NCBI	Rnor6.0
Rnor_5.0	1	82,661,278 - 82,661,409	UniSTS	Rnor5.0
RGSC_v3.4	1	79,821,865 - 79,821,996	UniSTS	RGSC3.4
Celera	1	74,582,014 - 74,582,145	UniSTS
RH 3.4 Map	1	822.1	UniSTS
Cytogenetic Map	1	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001135742	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000072750 ⟹ ENSRNOP00000064929

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	81,395,841 - 81,399,386 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081829 ⟹ ENSRNOP00000071992

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	81,396,558 - 81,399,672 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119508 ⟹ ENSRNOP00000082584

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	89,251,753 - 89,259,791 (+)	Ensembl
mRatBN7.2 Ensembl	1	80,123,925 - 80,131,881 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000160415 ⟹ ENSRNOP00000112362

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	89,239,205 - 89,259,799 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000172042 ⟹ ENSRNOP00000109417

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	89,248,631 - 89,259,799 (+)	Ensembl

RefSeq Acc Id:

NM_001135742 ⟹ NP_001129214

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	89,251,846 - 89,259,799 (+)	NCBI
mRatBN7.2	1	80,123,925 - 80,131,881 (+)	NCBI
Rnor_6.0	1	81,395,922 - 81,403,872 (+)	NCBI
Rnor_5.0	1	82,656,242 - 82,664,190 (+)	NCBI
RGSC_v3.4	1	79,816,826 - 79,824,777 (+)	RGD
Celera	1	74,576,973 - 74,584,923 (+)	NCBI

Sequence:

show sequence

CTCCAAGACACACCCGGTCGTGGAAGGAATGACGTCAGGATAGAGCCACCTGAAGGAGTCCGGA
TGTCTCTAAATCCGGACACCCCTTCCCCTTCAGCCGCTGTCATTTCGTCTTAAGGGGCCGGGCC
TCCGTGTTCTCCAGGCGTGTCACCTCTCTGCTCGCAATGCCTCTGCCTCAGGGTGATGTGACTG
CCTTATTCTTGGGGCCTCCCGGCTCGGGAAAGTCCGCGCTGATCGCCGCGTTATGCGGTAAGAA
TGTGGACGCGGTAGAAATTCCCGATGGACGGCCGGACTCTGGGGTCCCCAGCCTAAGAGCTGCA
GCTCCGGGCCTCTTCCTGGGTGAGCTGAGTTGCCCACCCGCAGCCCCCGGGCCCTGGGCGGCGG
AGGCCAACTTGCTGGTATTGGTGCTACCAGGATCTGAGGGAAGCGAGGAACCCTTGACCCCAGC
TCTGGGAGAGGCAGCACGGGCCGCCCTGGCCAGAGGAACCCCGCTGCTGGCTGTACGGAATCTG
CGTCCTGGAGATTCCCAGAATGCAGCTCAGGCCCGGGATGAGACTGCGGCCTTGCTGGACAGTG
CTGGGTTAGGAGCTGCGCCTCTCTTTGTGCTGCCCGCGGATTGCAGCAGCAGTGACGGCTGCGA
GGAGCTAGAGCGCCTGCAGGTGGTGCTGCGGACCCAGGCGGAGGCACTGCAGAGGCTCCTGCCT
CCTGCCCAGGATGGCTTCGAGGTGCTGGGCGCAGCAGAGCTGGAAGCTGTTCGTGAGGCCTTCG
AGACTGGTGGCCTGGAGGCGGCGCTGTCGTGGGTGCGCGCTGGTCTGGAGCGCCTAGGCAGCGC
TCGAGTGGACTTGGCGGTGGCCGGCACCACCAACGTAGGCCTTGTGCTGGACATGCTACTGGGG
TTGGAGCCTGGCGACGCGGGTGCTGCGCCTGCCTCTGCACCCACTGAGCCCACCCCTTATCCTG
CTCCAGAGCGCCCCAATGTAGTGCTCTGGACCGTTCCCCTGGGCCCCACAGCCACATCCCCTGC
CGTCACCCCTCACCCGACCCACTACGATGCCCTGATCCTCGTCACCCCTGGGGCTCCTACGGAG
GAGAACTGGGCCCAGGTCCGCTCGTTGGTGTCCCCAGATGCTCCACTCGTCGGTGTGCGCACTG
ACGGCCAGGGCGAAGATCCACCCGAGGTTCTGGAAGAAGAAAAGGCTGGGAATGCAAGGGATGG
GAACTCAGGCGATGCACGCAGCGAAGGAAAGAAACCTGGCATCGGGGACTCAGGATGCTCTGCG
GTTCGGAGCCCAGAGGATGAGCAGTGGGAGGTGCTGGAGGAGGCGCCTCCGCCCGTGTTCCCTC
TGAGGCCCGGCGGCCTCCCGGGCCTGGGAACTTGGCTGCAGCGGGCACTGCCCACAGCTCAGGC
GGGAGCGCTGCTGCTGGCGCTGCCACCCGCAAGTCCTCGGGCGGCGCGGAGGAAGGCGGCAGCA
TTGCGGGCAGGGGCGTGGAGGCCAGCCCTCCTGGCTAGCCTGGCGGCAGCCGCCGCTCCAGTAC
CAGGACTGGGCTGGGCTTGCGATGTGGCGCTTCTCCGGGGACAGCTGGCCGAGTGGAGGCGCGC
GCTGGGCATCGAACCTGCGGCCGTGGCACGAGAGCGCGCCTTGGGCCTGGCTCCCGGAGTACTG
GCCACGCGCACGCGCTTCCCGGGGCCGGTGACGCGAGCCGAGGTAGAGGCCAGGCTGGGGTCCT
GGGCAGGTGAGGGCACGGCCGGAGGTGCGGCATTGGGCGCGCTCTCCTTCCTATGGCCGGCCGG
TGGTGCAGCGGCAACAGGTGGGCTGGGTTACCGTGCTGCGCATGGTGTACTGCTGCAAGCCTTG
GATGAGATGCTGGCTGATGCTGAGGCGGTGCTGGGACCCCCAGAGCACAATCAGTAAGGCGCGC
GGTGGGGCTTGGGGCAACTGGTGACTTGGTTCGTAGCCCCATAGCCTCTGAGATTAAGGAGTGA
AGTTGTGTTACTCAAATCCGGAGACTTGAAGGAGACTGGCATCTCGTTGAAATCCGAGACCTAC
AGTCACCCGATTTCCGTGGCTCTGAATGGGAGTAAGGTCTATGCGCCAGAAGTGTGTCAGCCAG
ATACCAATGCAGTAAAGGGAATTGAGGGCCTGGGACTCATAGAAATGGGAGCCTTTTGGCGTCC
AGCTGACACCTGGTCCTCAATCTCTAGAAGCCTTGATTCCTGCCTTCCTATGAGTGAACCTATG
ACTATGGACCGGGTGCTTCAGGGAGTTAGAATCCTTGGAGCGCTGGGTCCCAAAGGGAAACGAG
ACGTAAGTTGTCCGATGAAAGAACAGATTTGCCGGAGCTGTGAGAGTCTTAGAAAAAGTCTGGT
TCCTAAGAAGGCTCTAGAGATTGGTTGTCATTTCTTGGGTGGTGGGAAGCCTGTGGGAGACCAG
GGGCCTGCTGGAGACCCTTTGATCTGGAGTGTGGAAGATTGTCATTTGCTCTTCAAGGCTTTGG
TGTAGAGAATACTGTCCCACAAAATTGAAGAGAAGGGACAGGGAGGGTCTGGGTAAGGTAGTCT
TCCGATGGTCAGAGCCTAAGAATGGGGCCTATAGGGTATGGAAAAATAGCAACCCACACTTGGA
AATACCTCCCTTGAGCCTCTGATGAACTGGGATCGTGGCTTTACTGGAAAAGGGTGTGACTACC
CCCATTTTATAGGTGCTGGGTGATTCAGGGTCTCCGGCATGTGTGCTCCTGTTTATTACTGGTT
TTTTCTGCCATATGGACCTTAACCGTTGGACCTCCTGCTCATCCGGAAAGGCAAGAGTCCTACT
GTGGCAGCCTATGGTTTTCTGCATGACGACCTCTGATCGATTTCTCCAAGATACGTGCTGCTGG
TCCACACAGGATGCTGCTGAGAGTGGGGGTCCCCCACAGGATAGCTGGGTAGGCCATTGACGCT
GGAGGAAAGTGCCAGGAGGGAGGCAGAGGCAGAAACCACAGTGCGCATGCGCATCAGCTTTGCA
CAGATGCGAGAAGCCATGTATGATTCCCCAGTGTTGAAAACAGGAGGGCGTGGCAGATGGGCCC
ACCCGGTTCAGAGAGGCAGTGTGTGGCCTGACCCTGCCTATTCTCGGTTCCCAGCCCATCTCCA
GCAAGCCTGATTTGTTGTTCTGATGCTCAGGTCCCGCCTCGGGACTTAGGCATGGTTTTCTATG
GAACACTCTGCCTCTCCGTCTTTTATGAGGTAGGGTCCTCATTGTCAGGTCTCCCCGAAATGGC
TCTATGATCACCCAAAGTAGCTTGCATTGATCCTGGCCACTTGATCGTCCCTGTAGCGAACATT
GCTATCAATGGCTTTATTTATTCACTCATTCATTTATTTGCCTGTTCATTGGCTCTTGCTCCTT
GCCTGTCTTTCTCTTGGGTGTACCCTAGTACCCAGAGCAGTGCCTGACACACGGTAGGTGCCTA
GTATTTATTATCCTGGTTTATTGATCATTGGCACATGGCCTGGAATTCAGGTTGTCAGTAACCT
TGTTACAAAAAAGGGACAAGCTAGGGAGAAGCGAGCCCCTGGTGGGAGAGCAAACCGAAGCAGG
AGAGCTTGGCCCCTGTCACCTCATGAGCAAGTGCCGTATATTTTCACCTGGTAGATGAAAGGAC
TGGACTAGAACCATAAGAGTTTCTGAGGGCTAGTGATTGGAGGTTGCATAGCTGGGCTTTACCC
CATCTAACCTTGAATTCTCACCTCTGACACCATTCACCCTATGAAAGGGGGCATCGGATTTGGC
TGTTCATGCCTGTAATCCCCGCGCCTCAGGTTGACACAGGAGAATTTGAAATGTAAGGCTGTCT
TCGGTGACATAGAGAATTGCAGGCCCATAAGCTTCATGCCTGATCCCATCAGAGTCTAGATGGA
CCTTGAACTCCACATGGTCTGGCCCTGAATCTTCTCATTCCCTGTTCAGCCCATCTCCAGCCAG
CCTGATACTAAGTCCTTCTCCATGCTTGACCAGCTTTGGCCCTGCCTCGGCCTCCCCAGTGCCA
GGGTTATGGCTCTAAACCACAGCACCTGGCTTCGATGTTAAAGCTCTTAGGTCAGCCTGACACT
TATCACCGAGTCACCAGAACAGATGCGTTCCTTACACCTGAGCACACCTCAGGTCACGTGATAG
ATCTAATTGGAAATACTTGATAGATTGAGGACCCAATTCACATACCCGTGTTTTAATTATATTT
GACAGGTCCCCCCCCCCCCCAATAGTTCAATCAATGCCTCACATATTAGAGGCAAACAGTCTGA
TGGAACCGTATCCCCAGCTCTGGGGGCTGGGGGTGGAGTTCTGGGCAGGGCCTCCACCACTAAG
CCACGCCCACAGGCCCTCATTGGGGGAGTCTAGGCAGGGGCTGTACCTCTGAGCTATGTCCATA
TTTCTAGACAAGGTCTCACTAAGTTGCCTGGGCTGCCCTTGAACTCACTGTATTCCAGACAGGC
CTTGAATTTGGGATCCTACTCTCAGCCTCCCAAGTAAGTGGGATCACAGGCCTGTCTCACCTCC
TGGCTCAGTTTTCTCAAACCTGCGATGTTCTGGTGGATCGAATACAAATAGGATCTGAGATTGA
TTCTTTTCCTCAGTGGCATTTGCCACACATTTGGATCACAGTTCAATAGCACAGCCCATTGTGG
GAGAACTATAGCGGCAAGAGAGGAGACGGGTATCCACATTGCACAGCCGCATTTGGGAAGTAGA
GAAATCACTCTCTCCTTTGTCTTCATCCCAGGACCACAGCTCTGAGGACTAGTGCCTCTAACAG
TAGGTGACCCCGCCTCATTTATCCCAGTCTAGACACTCCTCCACAGCCCTGGCCAGAGTTAATG
TGAATTCTGTCAGTTAACACTGACCATCACAGACAGCAGGTAGCTGAGGATTTGCTGTTACACA
CGCATGTGGCTAAGCATATGCATACTGGCACGTAAGTGTGCTCAAACACATACCCAGCTCACAG
GTACTGCAGCCCCTCCTCAGAAGCTTGGAACTCAATGTTATTCCTCTACTGCCTTGGCCCTATT
TCTTTGGTCTGGCTACAGTAACAGCCACCTTGCTCTCCTGTGACTTCCTGTTAAGTGTCCTGCA
TTCTCTAAACCCTCTGGTCCTTTGACTTCTTTTTTGGTATTTTGACATAGCCTAGGCTTGCCTT
CAACTCTGTATGTAGCCAGTGATGGCCTTGAAGTCCCAATCCTCCCTCCACCTCTCAAGTGCTG
GGATCACAGGCATGCGGCCCTATGCTCGGCTCTGACCATGTCCTGCTTTGGTGCCGCATGGCGT
CCCTGTCCTGTGCTTTGCTGCCGTCTCTTCTCCTTGAGGCCGGAGGCCCATGGTAGAGGCATCG
GGAAAAAGCACAATGTGGTCATTGTGCACGTTCTGGTCAGCTCCATAAACTTGTATACGGGCAC
TTTTGTGTGTTGGGATTCCTTGCCCATTTTTGTTTTGTTGCTTGGAGAGAGAATCTAGGCCATC
TCAAACACCTGAGGCCAGGTGCTCCTCCTGTCCCAGCCTCTCCTTGTCCTGGATTATAGGTAGA
GGTGGCTGCCTTTTAAACTATAATTCCCCCTCCCCCGAGATAGGGCCTTACTTACTCTATAACT
CTAACTCATGGCTTGGCATCTGAAGAGCTGGGGTTACCGGTGCAAATGACTACATGTTGCCTAT
GTGATCTTTTGTTAGGGTTTCTCAGCTTTTCCAGAATGTAAGTAAAGCTAAGAGTGAGACCTCC
GGAAGCCTCCAAATAGAAAAGGTTCAGTCTCCCTTGTCACAGGTCACTGGCTGCCAGCCGAGCT
CCCATGAGGCACTTCAGGTCTGGAAGAGCCTGGACACAGGAATTCTGGGAAATGTCAGTCTTCC
ATGCTGGAATTGCAACTATACAATCTTGGCATTGCCCTTGAAAGACAAGCAGGTTTCAGAAGTC
GGTGAATGAATGAGGTGCCCTCCTCAACATGGACAGAGTCTCACACTTCTGGCTCATGAAGGAA
CTGTCTATTAGAATGTGTGTGTGTGGGGGGGGGGGGGAATCTGTCTGGTCAACCTGTGGTGTGT
TTTGGAAAAAAGAATAAAAGGGTAGAAATACTA

hide sequence

RefSeq Acc Id:

XM_006228410 ⟹ XP_006228472

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	89,252,018 - 89,259,799 (+)	NCBI
mRatBN7.2	1	80,124,093 - 80,131,881 (+)	NCBI
Rnor_6.0	1	81,396,090 - 81,403,872 (+)	NCBI
Rnor_5.0	1	82,656,242 - 82,664,190 (+)	NCBI

Sequence:

show sequence

GATTTGGAACGGGGAGGGGAAAGACCATCCTCGAGTTCCCGAGTGATTGGCAGTCAGGTTTCTG
AGGGTTTTTGGGTTTTGTTTTGTTTTCTTTTTTTTTAAATAGAGAAATGCATTCGTGTGGAGAA
TGGGTATACACCTGACTCTCCAGGAAATAGGCCCTGGGGGTTGGGTTTCTAGGTCCTACAGTCT
GACGCTCGAGAATAGAAGTAGGCTGGAGGACTGAAACCTGGATCTACAGTGAAGCAGTTAGGAA
AGGGTGTTGACGGGTGTGGCGGCGCACGCCTTTAATCTCAGCACTCTGGGAGGCAAAGGCAAGA
AGATCTGAGTTTCAGGGCAACCTGGTCTACATAATGAGTTCAGGCCAGCCAGGGCTACACAGCG
AGACGCTGTCTTAGAAAAGAAGCAAACAAGACAGTCTTACATGTTTTCTGAGGGATGTCTTTCC
CCGCCTCTTGCTTTCCAGCAATGCCTCTGCCTCAGGGTGATGTGACTGCCTTATTCTTGGGGCC
TCCCGGCTCGGGAAAGTCCGCGCTGATCGCCGCGTTATGCGGTAAGAATGTGGACGCGGTAGAA
ATTCCCGATGGACGGCCGGACTCTGGGGTCCCCAGCCTAAGAGCTGCAGCTCCGGGCCTCTTCC
TGGGTGAGCTGAGTTGCCCACCCGCAGCCCCCGGGCCCTGGGCGGCGGAGGCCAACTTGCTGGT
ATTGGTGCTACCAGGATCTGAGGGAAGCGAGGAACCCTTGACCCCAGCTCTGGGAGAGGCAGCA
CGGGCCGCCCTGGCCAGAGGAACCCCGCTGCTGGCTGTACGGAATCTGCGTCCTGGAGATTCCC
AGAATGCAGCTCAGGCCCGGGATGAGACTGCGGCCTTGCTGGACAGTGCTGGGTTAGGAGCTGC
GCCTCTCTTTGTGCTGCCCGCGGATTGCAGCAGCAGTGACGGCTGCGAGGAGCTAGAGCGCCTG
CAGGTGGTGCTGCGGACCCAGGCGGAGGCACTGCAGAGGCTCCTGCCTCCTGCCCAGGATGGCT
TCGAGGTGCTGGGCGCAGCAGAGCTGGAAGCTGTTCGTGAGGCCTTCGAGACTGGTGGCCTGGA
GGCGGCGCTGTCGTGGGTGCGCGCTGGTCTGGAGCGCCTAGGCAGCGCTCGAGTGGACTTGGCG
GTGGCCGGCACCACCAACGTAGGCCTTGTGCTGGACATGCTACTGGGGTTGGAGCCTGGCGACG
CGGGTGCTGCGCCTGCCTCTGCACCCACTGAGCCCACCCCTTATCCTGCTCCAGAGCGCCCCAA
TGTAGTGCTCTGGACCGTTCCCCTGGGCCCCACAGCCACATCCCCTGCCGTCACCCCTCACCCG
ACCCACTACGATGCCCTGATCCTCGTCACCCCTGGGGCTCCTACGGAGGAGAACTGGGCCCAGG
TCCGCTCGTTGGTGTCCCCAGATGCTCCACTCGTCGGTGTGCGCACTGACGGCCAGGGCGAAGA
TCCACCCGAGGTTCTGGAAGAAGAAAAGGCTGGGAATGCAAGGGATGGGAACTCAGGCGATGCA
CGCAGCGAAGGAAAGAAACCTGGCATCGGGGACTCAGGATGCTCTGCGGTTCGGAGCCCAGAGG
ATGAGCAGTGGGAGGTGCTGGAGGAGGCGCCTCCGCCCGTGTTCCCTCTGAGGCCCGGCGGCCT
CCCGGGCCTGGGAACTTGGCTGCAGCGGGCACTGCCCACAGCTCAGGCGGGAGCGCTGCTGCTG
GCGCTGCCACCCGCAAGTCCTCGGGCGGCGCGGAGGAAGGCGGCAGCATTGCGGGCAGGGGCGT
GGAGGCCAGCCCTCCTGGCTAGCCTGGCGGCAGCCGCCGCTCCAGTACCAGGACTGGGCTGGGC
TTGCGATGTGGCGCTTCTCCGGGGACAGCTGGCCGAGTGGAGGCGCGCGCTGGGCATCGAACCT
GCGGCCGTGGCACGAGAGCGCGCCTTGGGCCTGGCTCCCGGAGTACTGGCCACGCGCACGCGCT
TCCCGGGGCCGGTGACGCGAGCCGAGGTAGAGGCCAGGCTGGGGTCCTGGGCAGGTGAGGGCAC
GGCCGGAGGTGCGGCATTGGGCGCGCTCTCCTTCCTATGGCCGGCCGGTGGTGCAGCGGCAACA
GGTGGGCTGGGTTACCGTGCTGCGCATGGTGTACTGCTGCAAGCCTTGGATGAGATGCTGGCTG
ATGCTGAGGCGGTGCTGGGACCCCCAGAGCACAATCAGTAAGGCGCGCGGTGGGGCTTGGGGCA
ACTGGTGACTTGGTTCGTAGCCCCATAGCCTCTGAGATTAAGGAGTGAAGTTGTGTTACTCAAA
TCCGGAGACTTGAAGGAGACTGGCATCTCGTTGAAATCCGAGACCTACAGTCACCCGATTTCCG
TGGCTCTGAATGGGAGTAAGGTCTATGCGCCAGAAGTGTGTCAGCCAGATACCAATGCAGTAAA
GGGAATTGAGGGCCTGGGACTCATAGAAATGGGAGCCTTTTGGCGTCCAGCTGACACCTGGTCC
TCAATCTCTAGAAGCCTTGATTCCTGCCTTCCTATGAGTGAACCTATGACTATGGACCGGGTGC
TTCAGGGAGTTAGAATCCTTGGAGCGCTGGGTCCCAAAGGGAAACGAGACGTAAGTTGTCCGAT
GAAAGAACAGATTTGCCGGAGCTGTGAGAGTCTTAGAAAAAGTCTGGTTCCTAAGAAGGCTCTA
GAGATTGGTTGTCATTTCTTGGGTGGTGGGAAGCCTGTGGGAGACCAGGGGCCTGCTGGAGACC
CTTTGATCTGGAGTGTGGAAGATTGTCATTTGCTCTTCAAGGCTTTGGTGTAGAGAATACTGTC
CCACAAAATTGAAGAGAAGGGACAGGGAGGGTCTGGGTAAGGTAGTCTTCCGATGGTCAGAGCC
TAAGAATGGGGCCTATAGGGTATGGAAAAATAGCAACCCACACTTGGAAATACCTCCCTTGAGC
CTCTGATGAACTGGGATCGTGGCTTTACTGGAAAAGGGTGTGACTACCCCCATTTTATAGGTGC
TGGGTGATTCAGGGTCTCCGGCATGTGTGCTCCTGTTTATTACTGGTTTTTTCTGCCATATGGA
CCTTAACCGTTGGACCTCCTGCTCATCCGGAAAGGCAAGAGTCCTACTGTGGCAGCCTATGGTT
TTCTGCATGACGACCTCTGATCGATTTCTCCAAGATACGTGCTGCTGGTCCACACAGGATGCTG
CTGAGAGTGGGGGTCCCCCACAGGATAGCTGGGTAGGCCATTGACGCTGGAGGAAAGTGCCAGG
AGGGAGGCAGAGGCAGAAACCACAGTGCGCATGCGCATCAGCTTTGCACAGATGCGAGAAGCCA
TGTATGATTCCCCAGTGTTGAAAACAGGAGGGCGTGGCAGATGGGCCCACCCGGTTCAGAGAGG
CAGTGTGTGGCCTGACCCTGCCTATTCTCGGTTCCCAGCCCATCTCCAGCAAGCCTGATTTGTT
GTTCTGATGCTCAGGTCCCGCCTCGGGACTTAGGCATGGTTTTCTATGGAACACTCTGCCTCTC
CGTCTTTTATGAGGTAGGGTCCTCATTGTCAGGTCTCCCCGAAATGGCTCTATGATCACCCAAA
GTAGCTTGCATTGATCCTGGCCACTTGATCGTCCCTGTAGCGAACATTGCTATCAATGGCTTTA
TTTATTCACTCATTCATTTATTTGCCTGTTCATTGGCTCTTGCTCCTTGCCTGTCTTTCTCTTG
GGTGTACCCTAGTACCCAGAGCAGTGCCTGACACACGGTAGGTGCCTAGTATTTATTATCCTGG
TTTATTGATCATTGGCACATGGCCTGGAATTCAGGTTGTCAGTAACCTTGTTACAAAAAAGGGA
CAAGCTAGGGAGAAGCGAGCCCCTGGTGGGAGAGCAAACCGAAGCAGGAGAGCTTGGCCCCTGT
CACCTCATGAGCAAGTGCCGTATATTTTCACCTGGTAGATGAAAGGACTGGACTAGAACCATAA
GAGTTTCTGAGGGCTAGTGATTGGAGGTTGCATAGCTGGGCTTTACCCCATCTAACCTTGAATT
CTCACCTCTGACACCATTCACCCTATGAAAGGGGGCATCGGATTTGGCTGTTCATGCCTGTAAT
CCCCGCGCCTCAGGTTGACACAGGAGAATTTGAAATGTAAGGCTGTCTTCGGTGACATAGAGAA
TTGCAGGCCCATAAGCTTCATGCCTGATCCCATCAGAGTCTAGATGGACCTTGAACTCCACATG
GTCTGGCCCTGAATCTTCTCATTCCCTGTTCAGCCCATCTCCAGCCAGCCTGATACTAAGTCCT
TCTCCATGCTTGACCAGCTTTGGCCCTGCCTCGGCCTCCCCAGTGCCAGGGTTATGGCTCTAAA
CCACAGCACCTGGCTTCGATGTTAAAGCTCTTAGGTCAGCCTGACACTTATCACCGAGTCACCA
GAACAGATGCGTTCCTTACACCTGAGCACACCTCAGGTCACGTGATAGATCTAATTGGAAATAC
TTGATAGATTGAGGACCCAATTCACATACCCGTGTTTTAATTATATTTGACAGGTCCCCCCCCC
CCCCAATAGTTCAATCAATGCCTCACATATTAGAGGCAAACAGTCTGATGGAACCGTATCCCCA
GCTCTGGGGGCTGGGGGTGGAGTTCTGGGCAGGGCCTCCACCACTAAGCCACGCCCACAGGCCC
TCATTGGGGGAGTCTAGGCAGGGGCTGTACCTCTGAGCTATGTCCATATTTCTAGACAAGGTCT
CACTAAGTTGCCTGGGCTGCCCTTGAACTCACTGTATTCCAGACAGGCCTTGAATTTGGGATCC
TACTCTCAGCCTCCCAAGTAAGTGGGATCACAGGCCTGTCTCACCTCCTGGCTCAGTTTTCTCA
AACCTGCGATGTTCTGGTGGATCGAATACAAATAGGATCTGAGATTGATTCTTTTCCTCAGTGG
CATTTGCCACACATTTGGATCACAGTTCAATAGCACAGCCCATTGTGGGAGAACTATAGCGGCA
AGAGAGGAGACGGGTATCCACATTGCACAGCCGCATTTGGGAAGTAGAGAAATCACTCTCTCCT
TTGTCTTCATCCCAGGACCACAGCTCTGAGGACTAGTGCCTCTAACAGTAGGTGACCCCGCCTC
ATTTATCCCAGTCTAGACACTCCTCCACAGCCCTGGCCAGAGTTAATGTGAATTCTGTCAGTTA
ACACTGACCATCACAGACAGCAGGTAGCTGAGGATTTGCTGTTACACACGCATGTGGCTAAGCA
TATGCATACTGGCACGTAAGTGTGCTCAAACACATACCCAGCTCACAGGTACTGCAGCCCCTCC
TCAGAAGCTTGGAACTCAATGTTATTCCTCTACTGCCTTGGCCCTATTTCTTTGGTCTGGCTAC
AGTAACAGCCACCTTGCTCTCCTGTGACTTCCTGTTAAGTGTCCTGCATTCTCTAAACCCTCTG
GTCCTTTGACTTCTTTTTTGGTATTTTGACATAGCCTAGGCTTGCCTTCAACTCTGTATGTAGC
CAGTGATGGCCTTGAAGTCCCAATCCTCCCTCCACCTCTCAAGTGCTGGGATCACAGGCATGCG
GCCCTATGCTCGGCTCTGACCATGTCCTGCTTTGGTGCCGCATGGCGTCCCTGTCCTGTGCTTT
GCTGCCGTCTCTTCTCCTTGAGGCCGGAGGCCCATGGTAGAGGCATCGGGAAAAAGCACAATGT
GGTCATTGTGCACGTTCTGGTCAGCTCCATAAACTTGTATACGGGCACTTTTGTGTGTTGGGAT
TCCTTGCCCATTTTTGTTTTGTTGCTTGGAGAGAGAATCTAGGCCATCTCAAACACCTGAGGCC
AGGTGCTCCTCCTGTCCCAGCCTCTCCTTGTCCTGGATTATAGGTAGAGGTGGCTGCCTTTTAA
ACTATAATTCCCCCTCCCCCGAGATAGGGCCTTACTTACTCTATAACTCTAACTCATGGCTTGG
CATCTGAAGAGCTGGGGTTACCGGTGCAAATGACTACATGTTGCCTATGTGATCTTTTGTTAGG
GTTTCTCAGCTTTTCCAGAATGTAAGTAAAGCTAAGAGTGAGACCTCCGGAAGCCTCCAAATAG
AAAAGGTTCAGTCTCCCTTGTCACAGGTCACTGGCTGCCAGCCGAGCTCCCATGAGGCACTTCA
GGTCTGGAAGAGCCTGGACACAGGAATTCTGGGAAATGTCAGTCTTCCATGCTGGAATTGCAAC
TATACAATCTTGGCATTGCCCTTGAAAGACAAGCAGGTTTCAGAAGTCGGTGAATGAATGAGGT
GCCCTCCTCAACATGGACAGAGTCTCACACTTCTGGCTCATGAAGGAACTGTCTATTAGAATGT
GTGTGTGTGGGGGGGGGGGGGAATCTGTCTGGTCAACCTGTGGTGTGTTTTGGAAAAAAGAATA
AAAGGGTAGAAATACTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001129214	(Get FASTA)	NCBI Sequence Viewer
	XP_006228472	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM08089	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000082584
	ENSRNOP00000082584.1
	ENSRNOP00000109417.1
	ENSRNOP00000112362.1

RefSeq Acc Id:

NP_001129214 ⟸ NM_001135742

- UniProtKB:

A0A8I5ZUT2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPLPQGDVTALFLGPPGSGKSALIAALCGKNVDAVEIPDGRPDSGVPSLRAAAPGLFLGELSCP
PAAPGPWAAEANLLVLVLPGSEGSEEPLTPALGEAARAALARGTPLLAVRNLRPGDSQNAAQAR
DETAALLDSAGLGAAPLFVLPADCSSSDGCEELERLQVVLRTQAEALQRLLPPAQDGFEVLGAA
ELEAVREAFETGGLEAALSWVRAGLERLGSARVDLAVAGTTNVGLVLDMLLGLEPGDAGAAPAS
APTEPTPYPAPERPNVVLWTVPLGPTATSPAVTPHPTHYDALILVTPGAPTEENWAQVRSLVSP
DAPLVGVRTDGQGEDPPEVLEEEKAGNARDGNSGDARSEGKKPGIGDSGCSAVRSPEDEQWEVL
EEAPPPVFPLRPGGLPGLGTWLQRALPTAQAGALLLALPPASPRAARRKAAALRAGAWRPALLA
SLAAAAAPVPGLGWACDVALLRGQLAEWRRALGIEPAAVARERALGLAPGVLATRTRFPGPVTR
AEVEARLGSWAGEGTAGGAALGALSFLWPAGGAAATGGLGYRAAHGVLLQALDEMLADAEAVLG
PPEHNQ

hide sequence

RefSeq Acc Id:

XP_006228472 ⟸ XM_006228410

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSFPASCFPAMPLPQGDVTALFLGPPGSGKSALIAALCGKNVDAVEIPDGRPDSGVPSLRAAAP
GLFLGELSCPPAAPGPWAAEANLLVLVLPGSEGSEEPLTPALGEAARAALARGTPLLAVRNLRP
GDSQNAAQARDETAALLDSAGLGAAPLFVLPADCSSSDGCEELERLQVVLRTQAEALQRLLPPA
QDGFEVLGAAELEAVREAFETGGLEAALSWVRAGLERLGSARVDLAVAGTTNVGLVLDMLLGLE
PGDAGAAPASAPTEPTPYPAPERPNVVLWTVPLGPTATSPAVTPHPTHYDALILVTPGAPTEEN
WAQVRSLVSPDAPLVGVRTDGQGEDPPEVLEEEKAGNARDGNSGDARSEGKKPGIGDSGCSAVR
SPEDEQWEVLEEAPPPVFPLRPGGLPGLGTWLQRALPTAQAGALLLALPPASPRAARRKAAALR
AGAWRPALLASLAAAAAPVPGLGWACDVALLRGQLAEWRRALGIEPAAVARERALGLAPGVLAT
RTRFPGPVTRAEVEARLGSWAGEGTAGGAALGALSFLWPAGGAAATGGLGYRAAHGVLLQALDE
MLADAEAVLGPPEHNQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000064929 ⟸ ENSRNOT00000072750

Ensembl Acc Id:

ENSRNOP00000071992 ⟸ ENSRNOT00000081829

Ensembl Acc Id:

ENSRNOP00000082584 ⟸ ENSRNOT00000119508

Ensembl Acc Id:

ENSRNOP00000109417 ⟸ ENSRNOT00000172042

Ensembl Acc Id:

ENSRNOP00000112362 ⟸ ENSRNOT00000160415

Protein Domains

IRG-type G

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K1U9-F1-model_v2	AlphaFold	A0A0G2K1U9	1-582	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689806

Promoter ID:

EPDNEW_R322

Type:

initiation region

Name:

Irgq_1

Description:

immunity-related GTPase Q

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	81,395,858 - 81,395,918	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309409	AgrOrtholog
BioCyc Gene	G2FUF-60440	BioCyc
Ensembl Genes	ENSRNOG00000046500	Ensembl
	ENSRNOG00000070901	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000119508	ENTREZGENE
	ENSRNOT00000119508.2	UniProtKB/TrEMBL
	ENSRNOT00000160415.1	UniProtKB/TrEMBL
	ENSRNOT00000172042.1	UniProtKB/TrEMBL
InterPro	G_IRG_dom	UniProtKB/TrEMBL
	IRGQ	UniProtKB/TrEMBL
NCBI Gene	292708	ENTREZGENE
PANTHER	IMMUNITY-RELATED GTPASE FAMILY Q PROTEIN	UniProtKB/TrEMBL
	PTHR19364	UniProtKB/TrEMBL
PhenoGen	Irgq	PhenoGen
PROSITE	G_IRG	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000046500	RatGTEx
	ENSRNOG00000070901	RatGTEx
UniProt	A0A8I5ZUT2	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0M2S5_RAT	UniProtKB/TrEMBL
	A0ABK0M8A2_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-05-04	Irgq	immunity-related GTPase Q	Irgq	immunity-related GTPase family, Q	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Irgq	immunity-related GTPase family, Q	Irgq_predicted	immunity-related GTPase family, Q (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Irgq_predicted	immunity-related GTPase family, Q (predicted)	RGD1309409_predicted	similar to FKSG27 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1309409_predicted	similar to FKSG27 (predicted)	LOC292708_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC292708_predicted	similar to FKSG27 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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