Mrc1 (mannose receptor, C type 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mrc1 (mannose receptor, C type 1) Rattus norvegicus
Analyze
Symbol: Mrc1
Name: mannose receptor, C type 1
RGD ID: 1309353
Description: Predicted to enable D-mannose binding activity; cargo receptor activity; and transmembrane signaling receptor activity. Predicted to be involved in receptor-mediated endocytosis. Predicted to act upstream of or within cellular response to interleukin-4; cellular response to lipopolysaccharide; and cellular response to type II interferon. Predicted to be located in cell surface and endosome membrane. Predicted to be active in plasma membrane. Orthologous to human MRC1 (mannose receptor C-type 1); PARTICIPATES IN phagocytosis pathway; tuberculosis pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC291327; macrophage mannose receptor 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81782,157,725 - 82,239,411 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1782,157,705 - 82,239,410 (+)EnsemblGRCr8
mRatBN7.21777,249,187 - 77,330,857 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1777,249,187 - 77,330,857 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1780,698,196 - 80,779,156 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01784,533,598 - 84,614,569 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01778,581,501 - 78,662,470 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01781,352,700 - 81,433,743 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1781,352,700 - 81,433,743 (+)Ensemblrn6Rnor6.0
Rnor_5.01783,099,574 - 83,180,623 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41788,411,265 - 88,492,622 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1776,583,460 - 76,664,122 (+)NCBICelera
RGSC_v3.11788,422,190 - 88,503,040 (+)NCBI
Cytogenetic Map17q12.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,5-hexanedione  (EXP)
2,6-dinitrotoluene  (EXP)
2-methoxyethanol  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
adenine  (ISO)
aflatoxin B1  (ISO)
agathisflavone  (EXP)
AM6545  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
Azoxymethane  (ISO)
baicalein  (ISO)
Bardoxolone methyl  (ISO)
benzo[a]pyrene  (EXP,ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
bosentan  (ISO)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon monoxide  (EXP)
carbon nanotube  (ISO)
carveol  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
choline  (ISO)
cocaine  (EXP)
cordycepin  (ISO)
corosolic acid  (ISO)
Cyclopamine  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (EXP)
deoxycholic acid  (ISO)
dextran sulfate  (ISO)
dichlorine  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
diuron  (EXP)
dopamine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP,ISO)
ethylparaben  (ISO)
etoposide  (ISO)
excitatory amino acid agonist  (EXP)
Fast green FCF  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
Gingerenone A  (ISO)
glyburide  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
GSK-J4  (ISO)
Harpagide  (ISO)
HU-308  (EXP)
isoliquiritigenin  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lipopolysaccharide  (EXP,ISO)
Luteolin 7-methyl ether  (ISO)
maneb  (ISO)
mechlorethamine  (EXP,ISO)
metformin  (ISO)
methidathion  (ISO)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
Morroniside  (ISO)
N,N-dimethylformamide  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nevirapine  (EXP)
nickel atom  (ISO)
nickel subsulfide  (EXP)
nimesulide  (EXP)
ochratoxin A  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paclitaxel  (EXP)
paeoniflorin  (EXP)
paracetamol  (ISO)
paraquat  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perindopril  (ISO)
phenobarbital  (ISO)
phenylarsine oxide  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
rutin  (EXP)
selenium atom  (ISO)
sevoflurane  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium benzoate  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
streptozocin  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
testosterone  (EXP)
tetrachloromethane  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
trimethyltin  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
ursolic acid  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
vinclozolin  (EXP)
WIN 55212-2  (EXP)
zinc sulfate  (ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (IEA,ISO)
endosome membrane  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Human mesenchymal stem cells modulate inflammatory cytokines after spinal cord injury in rat. Urdzíková LM, etal., Int J Mol Sci. 2014 Jun 25;15(7):11275-93. doi: 10.3390/ijms150711275.
Additional References at PubMed
PMID:1421407   PMID:19224860   PMID:20035344   PMID:22354962   PMID:22832163   PMID:24105692  


Genomics

Comparative Map Data
Mrc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81782,157,725 - 82,239,411 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1782,157,705 - 82,239,410 (+)EnsemblGRCr8
mRatBN7.21777,249,187 - 77,330,857 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1777,249,187 - 77,330,857 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1780,698,196 - 80,779,156 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01784,533,598 - 84,614,569 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01778,581,501 - 78,662,470 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01781,352,700 - 81,433,743 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1781,352,700 - 81,433,743 (+)Ensemblrn6Rnor6.0
Rnor_5.01783,099,574 - 83,180,623 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41788,411,265 - 88,492,622 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1776,583,460 - 76,664,122 (+)NCBICelera
RGSC_v3.11788,422,190 - 88,503,040 (+)NCBI
Cytogenetic Map17q12.3NCBI
MRC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381017,809,348 - 17,911,164 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1017,809,014 - 17,911,164 (+)Ensemblhg38GRCh38
GRCh371018,098,337 - 18,200,093 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361018,138,358 - 18,240,097 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341018,138,357 - 18,240,096NCBI
Celera1017,784,841 - 17,886,612 (+)NCBICelera
Cytogenetic Map10p12.33NCBI
HuRef1017,764,080 - 17,866,209 (+)NCBIHuRef
CHM1_11018,109,965 - 18,199,387 (+)NCBICHM1_1
T2T-CHM13v2.01017,828,682 - 17,930,487 (+)NCBIT2T-CHM13v2.0
Mrc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39214,234,225 - 14,336,834 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl214,234,203 - 14,336,868 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38214,229,414 - 14,332,023 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl214,229,392 - 14,332,057 (+)Ensemblmm10GRCm38
MGSCv37214,151,041 - 14,253,650 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36214,147,168 - 14,249,543 (+)NCBIMGSCv36mm8
Celera214,132,507 - 14,234,218 (+)NCBICelera
Cytogenetic Map2A2NCBI
cM Map210.46NCBI
Mrc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542910,139,355 - 10,232,600 (-)Ensembl
ChiLan1.0NW_00495542910,139,398 - 10,232,541 (-)NCBIChiLan1.0ChiLan1.0
MRC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2830,653,624 - 30,756,013 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11030,658,945 - 30,761,336 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01018,128,280 - 18,230,438 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11018,398,310 - 18,500,367 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1018,398,310 - 18,500,367 (+)EnsemblpanPan2panpan1.1
MRC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1219,090,580 - 19,185,943 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl219,069,120 - 19,185,691 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha216,192,173 - 16,287,442 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0219,382,161 - 19,474,894 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl219,382,822 - 19,474,835 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1216,582,950 - 16,678,085 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0217,418,222 - 17,513,475 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0218,038,475 - 18,133,728 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mrc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934418,413,121 - 18,497,481 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365209,463,007 - 9,547,257 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365209,463,007 - 9,547,321 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1044,107,072 - 44,226,733 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11044,107,926 - 44,226,734 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21048,841,154 - 48,960,925 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1917,751,053 - 17,849,258 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl917,751,133 - 17,849,406 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605123,397,347 - 23,496,696 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479610,145,610 - 10,180,671 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla_female_1.0 EnsemblNW_00462479610,040,859 - 10,138,420 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479610,041,483 - 10,184,458 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mrc1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1149,311,830 - 9,388,735 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mrc1
722 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:242
Count of miRNA genes:156
Interacting mature miRNAs:183
Transcripts:ENSRNOT00000024736
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)177061350286062352Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176369714782818564Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)176456982086954580Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 87 59 6 349 187 11 143 79 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000024736   ⟹   ENSRNOP00000024736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1782,157,705 - 82,239,410 (+)Ensembl
mRatBN7.2 Ensembl1777,249,187 - 77,330,857 (+)Ensembl
Rnor_6.0 Ensembl1781,352,700 - 81,433,743 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112068   ⟹   ENSRNOP00000077081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1782,166,730 - 82,238,654 (+)Ensembl
mRatBN7.2 Ensembl1777,258,192 - 77,330,100 (+)Ensembl
RefSeq Acc Id: NM_001106123   ⟹   NP_001099593
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81782,157,725 - 82,239,411 (+)NCBI
mRatBN7.21777,249,187 - 77,330,857 (+)NCBI
Rnor_6.01781,352,700 - 81,433,743 (+)NCBI
Rnor_5.01783,099,574 - 83,180,623 (+)NCBI
RGSC_v3.41788,411,265 - 88,492,622 (+)RGD
Celera1776,583,460 - 76,664,122 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063276254   ⟹   XP_063132324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81782,168,532 - 82,239,411 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001099593 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132324 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL78733 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024736
  ENSRNOP00000024736.8
  ENSRNOP00000077081.1
RefSeq Acc Id: NP_001099593   ⟸   NM_001106123
- Peptide Label: precursor
- UniProtKB: D3ZD31 (UniProtKB/TrEMBL),   A6JM56 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024736   ⟸   ENSRNOT00000024736
Ensembl Acc Id: ENSRNOP00000077081   ⟸   ENSRNOT00000112068
RefSeq Acc Id: XP_063132324   ⟸   XM_063276254
- Peptide Label: isoform X1
- UniProtKB: A0A8I5XVS2 (UniProtKB/TrEMBL),   A6JM56 (UniProtKB/TrEMBL),   D3ZD31 (UniProtKB/TrEMBL)
Protein Domains
C-type lectin   Fibronectin type-II

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZD31-F1-model_v2 AlphaFold D3ZD31 1-1456 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700599
Promoter ID:EPDNEW_R11123
Type:single initiation site
Name:Mrc1_1
Description:mannose receptor, C type 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01781,352,684 - 81,352,744EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309353 AgrOrtholog
BioCyc Gene G2FUF-8602 BioCyc
Ensembl Genes ENSRNOG00000018251 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024736 ENTREZGENE
  ENSRNOT00000024736.9 UniProtKB/TrEMBL
  ENSRNOT00000112068.2 UniProtKB/TrEMBL
Gene3D-CATH 2.10.10.10 UniProtKB/TrEMBL
  2.80.10.50 UniProtKB/TrEMBL
  3.10.100.10 UniProtKB/TrEMBL
InterPro C-type_lectin UniProtKB/TrEMBL
  C-type_lectin-like UniProtKB/TrEMBL
  C-type_lectin/snaclec_domain UniProtKB/TrEMBL
  C-type_lectin_CS UniProtKB/TrEMBL
  C-type_lectin_fold UniProtKB/TrEMBL
  FN_type2_col-bd UniProtKB/TrEMBL
  FN_type2_sf UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  Ricin_B-like_lectins UniProtKB/TrEMBL
  Ricin_B_lectin UniProtKB/TrEMBL
NCBI Gene 291327 ENTREZGENE
PANTHER MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED UniProtKB/TrEMBL
Pfam CysR_MRC2_N UniProtKB/TrEMBL
  fn2 UniProtKB/TrEMBL
  Lectin_C UniProtKB/TrEMBL
PhenoGen Mrc1 PhenoGen
PRINTS FNTYPEII UniProtKB/TrEMBL
PROSITE C_TYPE_LECTIN_1 UniProtKB/TrEMBL
  C_TYPE_LECTIN_2 UniProtKB/TrEMBL
  FN2_1 UniProtKB/TrEMBL
  FN2_2 UniProtKB/TrEMBL
  RICIN_B_LECTIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018251 RatGTEx
SMART CLECT UniProtKB/TrEMBL
  FN2 UniProtKB/TrEMBL
  RICIN UniProtKB/TrEMBL
Superfamily-SCOP C-type_lectin_fold UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  RicinB_like UniProtKB/TrEMBL
UniProt A0A8I5XVS2 ENTREZGENE, UniProtKB/TrEMBL
  A6JM56 ENTREZGENE, UniProtKB/TrEMBL
  D3ZD31 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Mrc1  mannose receptor, C type 1   Mrc1_predicted  mannose receptor, C type 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mrc1_predicted  mannose receptor, C type 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED