Ppp1r12b (protein phosphatase 1, regulatory subunit 12B) - Rat Genome Database

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Pathways
Gene: Ppp1r12b (protein phosphatase 1, regulatory subunit 12B) Rattus norvegicus
Analyze
Symbol: Ppp1r12b
Name: protein phosphatase 1, regulatory subunit 12B
RGD ID: 1309287
Description: Predicted to enable enzyme inhibitor activity and myosin phosphatase regulator activity. Predicted to be involved in neuron projection morphogenesis. Predicted to be located in stress fiber. Predicted to be active in A band and Z disc. Orthologous to human PPP1R12B (protein phosphatase 1 regulatory subunit 12B); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC304813; protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81348,751,256 - 48,948,933 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1348,751,477 - 48,948,922 (-)EnsemblGRCr8
mRatBN7.21346,199,418 - 46,397,108 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,201,251 - 46,397,108 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1348,805,925 - 49,003,623 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,093,993 - 50,291,695 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,360,066 - 47,557,419 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01351,583,603 - 51,784,641 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,584,299 - 51,784,639 (-)Ensemblrn6Rnor6.0
Rnor_5.01356,637,005 - 56,836,014 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41347,705,569 - 47,917,673 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1346,526,402 - 46,722,920 (-)NCBICelera
RGSC_v3.11347,729,746 - 47,931,553 (-)NCBI
Cytogenetic Map13q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
A band  (IBA,IEA,ISO)
cytoplasm  (IBA,IEA)
stress fiber  (IEA)
Z disc  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11067852   PMID:33096475   PMID:35352799  


Genomics

Comparative Map Data
Ppp1r12b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81348,751,256 - 48,948,933 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1348,751,477 - 48,948,922 (-)EnsemblGRCr8
mRatBN7.21346,199,418 - 46,397,108 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,201,251 - 46,397,108 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1348,805,925 - 49,003,623 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,093,993 - 50,291,695 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,360,066 - 47,557,419 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01351,583,603 - 51,784,641 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,584,299 - 51,784,639 (-)Ensemblrn6Rnor6.0
Rnor_5.01356,637,005 - 56,836,014 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41347,705,569 - 47,917,673 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1346,526,402 - 46,722,920 (-)NCBICelera
RGSC_v3.11347,729,746 - 47,931,553 (-)NCBI
Cytogenetic Map13q13NCBI
PPP1R12B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381202,348,699 - 202,592,702 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1202,348,666 - 202,592,706 (+)Ensemblhg38GRCh38
GRCh371202,317,827 - 202,561,830 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361200,584,459 - 200,824,320 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341199,049,492 - 199,289,354NCBI
Celera1175,441,739 - 175,684,836 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1173,483,918 - 173,723,526 (+)NCBIHuRef
CHM1_11203,740,082 - 203,979,944 (+)NCBICHM1_1
T2T-CHM13v2.01201,610,813 - 201,854,508 (+)NCBIT2T-CHM13v2.0
Ppp1r12b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,682,396 - 134,883,699 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1134,682,396 - 134,883,680 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381134,754,658 - 134,955,963 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,754,658 - 134,955,942 (-)Ensemblmm10GRCm38
MGSCv371136,662,520 - 136,852,517 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361136,571,069 - 136,772,351 (-)NCBIMGSCv36mm8
Celera1137,390,041 - 137,584,808 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
Ppp1r12b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540638,405,535 - 38,629,688 (+)Ensembl
ChiLan1.0NW_00495540638,405,297 - 38,636,503 (+)NCBIChiLan1.0ChiLan1.0
PPP1R12B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2146,793,994 - 47,036,171 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1146,760,651 - 46,998,751 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01177,945,674 - 178,185,871 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11182,243,497 - 182,482,216 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1182,243,497 - 182,482,216 (+)EnsemblpanPan2panpan1.1
PPP1R12B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17512,692 - 713,848 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7512,575 - 713,709 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha7561,883 - 766,819 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.07517,183 - 722,439 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl7517,388 - 722,447 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.17505,819 - 710,889 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07616,770 - 819,263 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07637,977 - 843,111 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ppp1r12b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,757,815 - 72,973,959 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365671,992,495 - 2,208,684 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365671,992,487 - 2,208,611 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R12B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1024,465,041 - 24,637,358 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11024,463,900 - 24,637,361 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21028,860,843 - 28,972,139 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R12B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,832,411 - 27,063,528 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2526,833,355 - 27,062,870 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605527,605,675 - 27,842,303 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r12b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248078,209,547 - 8,414,511 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248078,203,118 - 8,414,121 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ppp1r12b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v110751,603 - 943,297 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ppp1r12b
1365 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:892
Count of miRNA genes:327
Interacting mature miRNAs:441
Transcripts:ENSRNOT00000006671
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134627292251216694Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134599007750392939Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
12879472Bp399Blood pressure QTL 399arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134778041850392939Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
BF386425  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21346,208,309 - 46,208,459 (+)MAPPERmRatBN7.2
Rnor_6.01351,592,262 - 51,592,411NCBIRnor6.0
Rnor_5.01356,645,153 - 56,645,302UniSTSRnor5.0
RGSC_v3.41347,713,431 - 47,713,580UniSTSRGSC3.4
Celera1346,535,040 - 46,535,189UniSTS
RH 3.4 Map13180.0UniSTS
Cytogenetic Map13q13UniSTS
AU048021  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21346,350,695 - 46,350,988 (+)MAPPERmRatBN7.2
Rnor_6.01351,736,625 - 51,736,915NCBIRnor6.0
Rnor_5.01356,788,000 - 56,788,290UniSTSRnor5.0
RGSC_v3.41347,869,521 - 47,869,811UniSTSRGSC3.4
Celera1346,677,179 - 46,677,469UniSTS
Cytogenetic Map13q13UniSTS
RH138368  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21346,384,010 - 46,384,182 (+)MAPPERmRatBN7.2
Rnor_6.01351,769,938 - 51,770,109NCBIRnor6.0
Rnor_5.01356,821,313 - 56,821,484UniSTSRnor5.0
RGSC_v3.41347,902,834 - 47,903,005UniSTSRGSC3.4
Celera1346,710,497 - 46,710,668UniSTS
RH 3.4 Map13168.4UniSTS
Cytogenetic Map13q13UniSTS
BF390593  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21346,256,618 - 46,256,789 (+)MAPPERmRatBN7.2
Rnor_6.01351,640,919 - 51,641,089NCBIRnor6.0
Rnor_5.01356,693,435 - 56,693,605UniSTSRnor5.0
RGSC_v3.41347,765,746 - 47,765,916UniSTSRGSC3.4
Celera1346,583,352 - 46,583,522UniSTS
RH 3.4 Map13181.7UniSTS
Cytogenetic Map13q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010056917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000089068   ⟹   ENSRNOP00000069748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1348,751,477 - 48,948,922 (-)Ensembl
mRatBN7.2 Ensembl1346,201,251 - 46,397,108 (-)Ensembl
Rnor_6.0 Ensembl1351,584,299 - 51,784,639 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100428   ⟹   ENSRNOP00000087409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1348,756,370 - 48,948,922 (-)Ensembl
mRatBN7.2 Ensembl1346,204,743 - 46,397,090 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100540   ⟹   ENSRNOP00000087080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1348,762,420 - 48,948,922 (-)Ensembl
mRatBN7.2 Ensembl1346,210,583 - 46,397,108 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107681   ⟹   ENSRNOP00000086607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1348,756,370 - 48,948,922 (-)Ensembl
mRatBN7.2 Ensembl1346,204,743 - 46,397,090 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119339   ⟹   ENSRNOP00000090864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1348,756,370 - 48,798,104 (-)Ensembl
mRatBN7.2 Ensembl1346,204,743 - 46,247,470 (-)Ensembl
RefSeq Acc Id: NM_001107178   ⟹   NP_001100648
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,751,477 - 48,948,922 (-)NCBI
mRatBN7.21346,199,639 - 46,397,108 (-)NCBI
Rnor_6.01351,583,603 - 51,784,639 (-)NCBI
Rnor_5.01356,637,005 - 56,836,014 (-)NCBI
RGSC_v3.41347,705,569 - 47,917,673 (-)RGD
Celera1346,526,402 - 46,722,920 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249875   ⟹   XP_006249937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,757,314 - 48,948,916 (-)NCBI
mRatBN7.21346,205,477 - 46,397,102 (-)NCBI
Rnor_6.01351,589,479 - 51,784,640 (-)NCBI
Rnor_5.01356,637,005 - 56,836,014 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249876   ⟹   XP_006249938
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,751,256 - 48,948,916 (-)NCBI
mRatBN7.21346,199,418 - 46,397,102 (-)NCBI
Rnor_6.01351,587,214 - 51,784,639 (-)NCBI
Rnor_5.01356,637,005 - 56,836,014 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249880   ⟹   XP_006249942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,757,319 - 48,948,605 (-)NCBI
mRatBN7.21346,205,487 - 46,396,786 (-)NCBI
Rnor_6.01351,589,488 - 51,784,267 (-)NCBI
Rnor_5.01356,637,005 - 56,836,014 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769558   ⟹   XP_008767780
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,866,459 - 48,948,916 (-)NCBI
mRatBN7.21346,314,621 - 46,397,102 (-)NCBI
Rnor_6.01351,706,887 - 51,784,641 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769561   ⟹   XP_008767783
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,751,256 - 48,801,029 (-)NCBI
mRatBN7.21346,199,418 - 46,247,839 (-)NCBI
Rnor_6.01351,587,214 - 51,631,731 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598793   ⟹   XP_017454282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,773,464 - 48,948,916 (-)NCBI
mRatBN7.21346,221,638 - 46,397,102 (-)NCBI
Rnor_6.01351,609,964 - 51,784,640 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090718   ⟹   XP_038946646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,762,583 - 48,948,916 (-)NCBI
mRatBN7.21346,211,324 - 46,397,102 (-)NCBI
RefSeq Acc Id: XM_039090719   ⟹   XP_038946647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,757,319 - 48,948,916 (-)NCBI
mRatBN7.21346,205,487 - 46,397,102 (-)NCBI
RefSeq Acc Id: XM_039090720   ⟹   XP_038946648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,773,486 - 48,948,916 (-)NCBI
mRatBN7.21346,221,652 - 46,397,102 (-)NCBI
RefSeq Acc Id: XM_063272300   ⟹   XP_063128370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,827,410 - 48,948,916 (-)NCBI
RefSeq Acc Id: XM_063272301   ⟹   XP_063128371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,757,319 - 48,845,362 (-)NCBI
RefSeq Acc Id: XM_063272303   ⟹   XP_063128373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,751,256 - 48,948,933 (-)NCBI
RefSeq Acc Id: XR_005492243
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,866,427 - 48,948,916 (-)NCBI
mRatBN7.21346,315,687 - 46,397,102 (-)NCBI
RefSeq Acc Id: XR_010056917
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,867,516 - 48,948,916 (-)NCBI
RefSeq Acc Id: NP_001100648   ⟸   NM_001107178
- UniProtKB: D3ZIC4 (UniProtKB/TrEMBL),   A6ICC9 (UniProtKB/TrEMBL),   A0A8I6A534 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249938   ⟸   XM_006249876
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A6B6 (UniProtKB/TrEMBL),   A0A8I6A534 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249937   ⟸   XM_006249875
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A534 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249942   ⟸   XM_006249880
- Peptide Label: isoform X8
- UniProtKB: A0A8I6A534 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767783   ⟸   XM_008769561
- Peptide Label: isoform X11
- UniProtKB: A0A8I6GIK9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767780   ⟸   XM_008769558
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017454282   ⟸   XM_017598793
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A534 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069748   ⟸   ENSRNOT00000089068
RefSeq Acc Id: XP_038946647   ⟸   XM_039090719
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A534 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946646   ⟸   XM_039090718
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A534 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946648   ⟸   XM_039090720
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A534 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000087080   ⟸   ENSRNOT00000100540
Ensembl Acc Id: ENSRNOP00000090864   ⟸   ENSRNOT00000119339
Ensembl Acc Id: ENSRNOP00000087409   ⟸   ENSRNOT00000100428
Ensembl Acc Id: ENSRNOP00000086607   ⟸   ENSRNOT00000107681
RefSeq Acc Id: XP_063128373   ⟸   XM_063272303
- Peptide Label: isoform X12
- UniProtKB: A0A8I6A534 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128371   ⟸   XM_063272301
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063128370   ⟸   XM_063272300
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A534 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIC4-F1-model_v2 AlphaFold D3ZIC4 1-993 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698836
Promoter ID:EPDNEW_R9360
Type:multiple initiation site
Name:Ppp1r12b_1
Description:protein phosphatase 1, regulatory subunit 12B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01351,784,634 - 51,784,694EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309287 AgrOrtholog
BioCyc Gene G2FUF-18223 BioCyc
Ensembl Genes ENSRNOG00000051440 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000089068 ENTREZGENE
  ENSRNOT00000089068.3 UniProtKB/TrEMBL
  ENSRNOT00000100428 ENTREZGENE
  ENSRNOT00000100428.2 UniProtKB/TrEMBL
  ENSRNOT00000100540 ENTREZGENE
  ENSRNOT00000100540.2 UniProtKB/TrEMBL
  ENSRNOT00000107681 ENTREZGENE
  ENSRNOT00000107681.2 UniProtKB/TrEMBL
  ENSRNOT00000119339 ENTREZGENE
  ENSRNOT00000119339.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  6.10.140.390 UniProtKB/TrEMBL
  6.10.250.1820 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  MYPT1/MYPT2/Mbs85 UniProtKB/TrEMBL
  PP1_Regulatory_Subunit UniProtKB/TrEMBL
  PRKG1_interact UniProtKB/TrEMBL
KEGG Report rno:304813 UniProtKB/TrEMBL
NCBI Gene 304813 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 UniProtKB/TrEMBL
  PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12B UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  PRKG1_interact UniProtKB/TrEMBL
PhenoGen Ppp1r12b PhenoGen
PIRSF PP1_12ABC_vert UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051440 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
UniProt A0A8I6A534 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A6B6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GFZ2_RAT UniProtKB/TrEMBL
  A0A8I6GIK9 ENTREZGENE, UniProtKB/TrEMBL
  A6ICC9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIC4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-10-18 Ppp1r12b  protein phosphatase 1, regulatory subunit 12B  Ppp1r12b  protein phosphatase 1, regulatory (inhibitor) subunit 12B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ppp1r12b  protein phosphatase 1, regulatory (inhibitor) subunit 12B   Ppp1r12b_predicted  protein phosphatase 1, regulatory (inhibitor) subunit 12B (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ppp1r12b_predicted  protein phosphatase 1, regulatory (inhibitor) subunit 12B (predicted)      Symbol and Name status set to approved 70820 APPROVED