Agap1 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 1) - Rat Genome Database

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Gene: Agap1 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 1) Rattus norvegicus
Analyze
Symbol: Agap1
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
RGD ID: 1309244
Description: Predicted to enable GTPase activator activity; GTPase activity; and phospholipid binding activity. Involved in regulation of modification of postsynaptic structure. Is active in postsynaptic endosome. Orthologous to human AGAP1 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 1); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1; centaurin, gamma 2; Centg2; LOC316611
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8997,487,382 - 97,922,870 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl997,487,406 - 97,922,870 (+)EnsemblGRCr8
mRatBN7.2990,039,720 - 90,475,196 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl990,039,605 - 90,470,958 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx998,466,362 - 98,901,849 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09103,602,274 - 104,037,749 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09101,967,803 - 102,403,281 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0996,718,901 - 97,034,400 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl996,621,586 - 97,030,163 (+)Ensemblrn6Rnor6.0
Rnor_5.0996,414,188 - 96,724,155 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4988,711,408 - 88,994,380 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera987,739,807 - 88,021,762 (+)NCBICelera
RGSC_v3.1988,861,495 - 89,198,155 (+)NCBI
Cytogenetic Map9q35-q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
fonofos  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
lead(0)  (ISO)
maleic acid  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctanoic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
terbufos  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin. Arnold M, etal., Front Cell Neurosci. 2016 Sep 22;10:218. doi: 10.3389/fncel.2016.00218. eCollection 2016.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15381706   PMID:18954304   PMID:20664521   PMID:25931508  


Genomics

Comparative Map Data
Agap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8997,487,382 - 97,922,870 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl997,487,406 - 97,922,870 (+)EnsemblGRCr8
mRatBN7.2990,039,720 - 90,475,196 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl990,039,605 - 90,470,958 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx998,466,362 - 98,901,849 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09103,602,274 - 104,037,749 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09101,967,803 - 102,403,281 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0996,718,901 - 97,034,400 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl996,621,586 - 97,030,163 (+)Ensemblrn6Rnor6.0
Rnor_5.0996,414,188 - 96,724,155 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4988,711,408 - 88,994,380 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera987,739,807 - 88,021,762 (+)NCBICelera
RGSC_v3.1988,861,495 - 89,198,155 (+)NCBI
Cytogenetic Map9q35-q36NCBI
AGAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382235,494,043 - 236,131,793 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2235,494,043 - 236,131,793 (+)Ensemblhg38GRCh38
GRCh372236,402,687 - 237,040,437 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,067,475 - 236,698,866 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342236,184,769 - 236,815,863NCBI
Celera2230,115,921 - 230,747,258 (+)NCBICelera
Cytogenetic Map2q37.2NCBI
HuRef2228,413,571 - 228,835,033 (+)NCBIHuRef
CHM1_12236,408,551 - 237,046,244 (+)NCBICHM1_1
T2T-CHM13v2.02235,983,538 - 236,621,510 (+)NCBIT2T-CHM13v2.0
Agap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39189,382,533 - 89,823,004 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl189,382,528 - 89,825,339 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38189,454,811 - 89,895,282 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl189,454,806 - 89,897,617 (+)Ensemblmm10GRCm38
MGSCv37191,351,386 - 91,791,857 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36191,285,982 - 91,726,453 (+)NCBIMGSCv36mm8
Celera192,388,739 - 92,836,477 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map145.06NCBI
AGAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213138,121,502 - 138,761,901 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B138,136,463 - 138,776,865 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B122,722,529 - 123,363,009 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B241,802,578 - 242,223,839 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B241,802,544 - 242,216,166 (+)EnsemblpanPan2panpan1.1
AGAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12546,449,668 - 46,980,358 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2546,449,705 - 46,973,719 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2546,949,451 - 47,480,836 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02546,800,549 - 47,332,157 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2546,800,415 - 47,326,012 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12546,707,383 - 47,240,212 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02546,502,287 - 47,033,741 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02546,731,544 - 47,263,667 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Agap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303188,689,998 - 189,037,540 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365251,904,777 - 2,221,147 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365251,898,006 - 2,249,698 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15135,441,906 - 135,993,311 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115135,442,440 - 135,999,162 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215149,877,134 - 150,433,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AGAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110121,508,992 - 122,144,519 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10121,719,490 - 122,142,090 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604077,254,495 - 77,917,718 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248471,370,693 - 1,846,449 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248471,370,699 - 1,863,698 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Agap1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14161,465,711 - 161,893,746 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Agap1
5108 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:159
Count of miRNA genes:124
Interacting mature miRNAs:136
Transcripts:ENSRNOT00000065720
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)986720043110356905Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)985262459109044727Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat

Markers in Region
DXRat70  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4988,953,520 - 88,953,765RGDRGSC3.4
RGSC_v3.4988,953,521 - 88,953,765UniSTSRGSC3.4
Celera987,980,690 - 87,980,934UniSTS
RGSC_v3.1989,158,289 - 89,158,534RGD
Cytogenetic Map9q35UniSTS
D9Got113  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4988,954,119 - 88,954,275RGDRGSC3.4
RGSC_v3.4988,954,120 - 88,954,275UniSTSRGSC3.4
Celera987,981,289 - 87,981,444UniSTS
RGSC_v3.1989,158,888 - 89,159,044RGD
RH 2.0 Map9933.3RGD
Cytogenetic Map9q35UniSTS
RH143503  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2990,417,404 - 90,417,529 (+)MAPPERmRatBN7.2
Rnor_6.0996,974,851 - 96,974,975NCBIRnor6.0
Rnor_5.0996,667,282 - 96,667,406UniSTSRnor5.0
RGSC_v3.4988,940,840 - 88,940,964UniSTSRGSC3.4
Celera987,968,028 - 87,968,152UniSTS
Cytogenetic Map9q35UniSTS
BF387139  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2990,208,769 - 90,208,947 (+)MAPPERmRatBN7.2
Rnor_6.0996,767,188 - 96,767,365NCBIRnor6.0
Rnor_5.0996,459,645 - 96,459,822UniSTSRnor5.0
RGSC_v3.4988,732,154 - 88,732,331UniSTSRGSC3.4
Celera987,760,552 - 87,760,729UniSTS
Cytogenetic Map9q35UniSTS
BE102881  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2990,301,943 - 90,302,108 (+)MAPPERmRatBN7.2
Rnor_6.0996,860,228 - 96,860,392NCBIRnor6.0
Rnor_5.0996,552,685 - 96,552,849UniSTSRnor5.0
RGSC_v3.4988,825,449 - 88,825,613UniSTSRGSC3.4
Celera987,853,784 - 87,853,948UniSTS
Cytogenetic Map9q35UniSTS
RH139308  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2990,301,014 - 90,301,213 (+)MAPPERmRatBN7.2
Rnor_6.0996,859,300 - 96,859,497NCBIRnor6.0
Rnor_5.0996,551,757 - 96,551,954UniSTSRnor5.0
RGSC_v3.4988,824,520 - 88,824,718UniSTSRGSC3.4
Celera987,852,855 - 87,853,053UniSTS
Cytogenetic Map9q35UniSTS
RH140788  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2990,395,802 - 90,396,008 (+)MAPPERmRatBN7.2
Rnor_6.0996,953,242 - 96,953,447NCBIRnor6.0
Rnor_5.0996,645,673 - 96,645,878UniSTSRnor5.0
RGSC_v3.4988,919,238 - 88,919,443UniSTSRGSC3.4
Celera987,946,457 - 87,946,662UniSTS
Cytogenetic Map9q35UniSTS
UniSTS:234171  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2990,469,482 - 90,469,691 (+)MAPPERmRatBN7.2
Rnor_6.0997,028,688 - 97,028,896NCBIRnor6.0
Rnor_5.0996,718,443 - 96,718,651UniSTSRnor5.0
RGSC_v3.4988,992,905 - 88,993,113UniSTSRGSC3.4
Celera988,020,287 - 88,020,495UniSTS
Cytogenetic Map9q35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
18 13 84 216 91 90 59 144 59 6 470 271 22 194 114 122 31 34 34

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC158781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000065720   ⟹   ENSRNOP00000060109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl997,487,406 - 97,922,870 (+)Ensembl
mRatBN7.2 Ensembl990,188,025 - 90,470,958 (+)Ensembl
Rnor_6.0 Ensembl996,746,440 - 97,030,163 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088192   ⟹   ENSRNOP00000074469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl997,487,406 - 97,922,870 (+)Ensembl
mRatBN7.2 Ensembl990,039,605 - 90,470,958 (+)Ensembl
Rnor_6.0 Ensembl996,621,586 - 97,028,280 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104807   ⟹   ENSRNOP00000086357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl997,611,218 - 97,922,870 (+)Ensembl
mRatBN7.2 Ensembl990,163,093 - 90,470,958 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105657   ⟹   ENSRNOP00000093401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl997,610,553 - 97,922,870 (+)Ensembl
mRatBN7.2 Ensembl990,163,093 - 90,470,958 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107897   ⟹   ENSRNOP00000085146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl997,610,553 - 97,922,870 (+)Ensembl
mRatBN7.2 Ensembl990,163,093 - 90,470,958 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000128951   ⟹   ENSRNOP00000104606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl997,487,406 - 97,922,870 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000137621   ⟹   ENSRNOP00000108422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl997,487,406 - 97,922,870 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000163080   ⟹   ENSRNOP00000108259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl997,611,218 - 97,922,870 (+)Ensembl
RefSeq Acc Id: NM_001108230   ⟹   NP_001101700
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,487,406 - 97,922,870 (+)NCBI
mRatBN7.2990,039,720 - 90,475,196 (+)NCBI
Rnor_6.0996,746,440 - 97,030,163 (+)NCBI
Rnor_5.0996,414,188 - 96,724,155 (+)NCBI
RGSC_v3.4988,711,408 - 88,994,380 (+)RGD
Celera987,739,807 - 88,021,762 (+)RGD
Sequence:
RefSeq Acc Id: NM_001401593   ⟹   NP_001388522
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,487,406 - 97,922,870 (+)NCBI
mRatBN7.2990,039,720 - 90,475,196 (+)NCBI
RefSeq Acc Id: XM_006245402   ⟹   XP_006245464
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,922,870 (+)NCBI
mRatBN7.2990,159,574 - 90,475,196 (+)NCBI
Rnor_6.0996,718,902 - 97,034,400 (+)NCBI
Rnor_5.0996,414,188 - 96,724,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596490   ⟹   XP_017451979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,922,870 (+)NCBI
mRatBN7.2990,159,574 - 90,475,196 (+)NCBI
Rnor_6.0996,718,901 - 97,034,400 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596493   ⟹   XP_017451982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,922,870 (+)NCBI
mRatBN7.2990,159,571 - 90,475,196 (+)NCBI
Rnor_6.0996,718,901 - 97,034,400 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083744   ⟹   XP_038939672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,922,870 (+)NCBI
mRatBN7.2990,160,947 - 90,475,196 (+)NCBI
RefSeq Acc Id: XM_039083746   ⟹   XP_038939674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,922,870 (+)NCBI
mRatBN7.2990,160,933 - 90,475,196 (+)NCBI
RefSeq Acc Id: XM_039083751   ⟹   XP_038939679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,487,426 - 97,922,870 (+)NCBI
mRatBN7.2990,039,760 - 90,475,196 (+)NCBI
RefSeq Acc Id: XM_039083752   ⟹   XP_038939680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,487,426 - 97,922,870 (+)NCBI
mRatBN7.2990,039,760 - 90,475,196 (+)NCBI
RefSeq Acc Id: XM_063267297   ⟹   XP_063123367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267298   ⟹   XP_063123368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267299   ⟹   XP_063123369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267300   ⟹   XP_063123370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,609,668 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267301   ⟹   XP_063123371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,609,670 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267302   ⟹   XP_063123372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,909,211 (+)NCBI
RefSeq Acc Id: XM_063267303   ⟹   XP_063123373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267304   ⟹   XP_063123374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,912,729 (+)NCBI
RefSeq Acc Id: XM_063267305   ⟹   XP_063123375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,909,211 (+)NCBI
RefSeq Acc Id: XM_063267306   ⟹   XP_063123376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,607,233 - 97,912,729 (+)NCBI
RefSeq Acc Id: XM_063267307   ⟹   XP_063123377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,487,426 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267308   ⟹   XP_063123378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,487,382 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267309   ⟹   XP_063123379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,487,426 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267310   ⟹   XP_063123380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,487,426 - 97,922,870 (+)NCBI
RefSeq Acc Id: XM_063267311   ⟹   XP_063123381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8997,487,426 - 97,922,870 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101700 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388522 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245464 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451979 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451982 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939672 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939674 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939679 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939680 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123367 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123368 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123369 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123370 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123371 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123372 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123373 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123374 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123375 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123376 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123377 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123378 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123379 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123380 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123381 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58782 (Get FASTA)   NCBI Sequence Viewer  
  EDL92081 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000060109
  ENSRNOP00000060109.2
  ENSRNOP00000074469
  ENSRNOP00000074469.2
  ENSRNOP00000085146
  ENSRNOP00000085146.2
  ENSRNOP00000086357
  ENSRNOP00000086357.2
  ENSRNOP00000093401
  ENSRNOP00000093401.2
  ENSRNOP00000104606
  ENSRNOP00000104606.1
  ENSRNOP00000108259
  ENSRNOP00000108259.1
  ENSRNOP00000108422
  ENSRNOP00000108422.1
RefSeq Acc Id: NP_001101700   ⟸   NM_001108230
- Peptide Label: isoform 1
- UniProtKB: A0A0G2K847 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245464   ⟸   XM_006245402
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017451979   ⟸   XM_017596490
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017451982   ⟸   XM_017596493
- Peptide Label: isoform X5
- Sequence:
Ensembl Acc Id: ENSRNOP00000060109   ⟸   ENSRNOT00000065720
Ensembl Acc Id: ENSRNOP00000074469   ⟸   ENSRNOT00000088192
RefSeq Acc Id: XP_038939679   ⟸   XM_039083751
- Peptide Label: isoform X21
- UniProtKB: A0A0G2K847 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939680   ⟸   XM_039083752
- Peptide Label: isoform X22
- UniProtKB: A0A0G2K847 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939674   ⟸   XM_039083746
- Peptide Label: isoform X14
- UniProtKB: A0A8I6GDZ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939672   ⟸   XM_039083744
- Peptide Label: isoform X11
- UniProtKB: A0A8I6AWZ3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093401   ⟸   ENSRNOT00000105657
Ensembl Acc Id: ENSRNOP00000086357   ⟸   ENSRNOT00000104807
Ensembl Acc Id: ENSRNOP00000085146   ⟸   ENSRNOT00000107897
RefSeq Acc Id: NP_001388522   ⟸   NM_001401593
- Peptide Label: isoform 2
- UniProtKB: A0A0G2K847 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123378   ⟸   XM_063267308
- Peptide Label: isoform X17
- UniProtKB: A0A0G2K847 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123377   ⟸   XM_063267307
- Peptide Label: isoform X16
- UniProtKB: A0A0G2K847 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123381   ⟸   XM_063267311
- Peptide Label: isoform X20
- UniProtKB: A0A0G2K847 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123379   ⟸   XM_063267309
- Peptide Label: isoform X18
- UniProtKB: A0A0G2K847 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123380   ⟸   XM_063267310
- Peptide Label: isoform X19
- UniProtKB: A0A0G2K847 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123368   ⟸   XM_063267298
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063123369   ⟸   XM_063267299
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AWZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123373   ⟸   XM_063267303
- Peptide Label: isoform X10
- UniProtKB: A0A8I6GDZ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123367   ⟸   XM_063267297
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063123374   ⟸   XM_063267304
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063123376   ⟸   XM_063267306
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063123372   ⟸   XM_063267302
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063123375   ⟸   XM_063267305
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063123370   ⟸   XM_063267300
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AWZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123371   ⟸   XM_063267301
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A118 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108422   ⟸   ENSRNOT00000137621
Ensembl Acc Id: ENSRNOP00000104606   ⟸   ENSRNOT00000128951
Ensembl Acc Id: ENSRNOP00000108259   ⟸   ENSRNOT00000163080
Protein Domains
Arf-GAP   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K847-F1-model_v2 AlphaFold A0A0G2K847 1-889 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309244 AgrOrtholog
BioCyc Gene G2FUF-26772 BioCyc
Ensembl Genes ENSRNOG00000019476 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000065720 ENTREZGENE
  ENSRNOT00000065720.3 UniProtKB/TrEMBL
  ENSRNOT00000088192 ENTREZGENE
  ENSRNOT00000088192.3 UniProtKB/TrEMBL
  ENSRNOT00000104807 ENTREZGENE
  ENSRNOT00000104807.2 UniProtKB/TrEMBL
  ENSRNOT00000105657 ENTREZGENE
  ENSRNOT00000105657.2 UniProtKB/TrEMBL
  ENSRNOT00000107897 ENTREZGENE
  ENSRNOT00000107897.2 UniProtKB/TrEMBL
  ENSRNOT00000128951 ENTREZGENE
  ENSRNOT00000128951.1 UniProtKB/TrEMBL
  ENSRNOT00000137621 ENTREZGENE
  ENSRNOT00000137621.1 UniProtKB/TrEMBL
  ENSRNOT00000163080 ENTREZGENE
  ENSRNOT00000163080.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.150 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7135166 IMAGE-MGC_LOAD
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Arf-GAP_GTPase_ANK_PH UniProtKB/TrEMBL
  ArfGAP UniProtKB/TrEMBL
  ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
KEGG Report rno:316611 UniProtKB/TrEMBL
MGC_CLONE MGC:188116 IMAGE-MGC_LOAD
NCBI Gene 316611 ENTREZGENE
PANTHER ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  CENTAURIN-GAMMA-1A UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  ArfGap UniProtKB/TrEMBL
  Ras UniProtKB/TrEMBL
PhenoGen Agap1 PhenoGen
PRINTS REVINTRACTNG UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  ARFGAP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019476 RatGTEx
SMART ANK UniProtKB/TrEMBL
  ArfGap UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  SSF57863 UniProtKB/TrEMBL
UniProt A0A0G2K847 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A118 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AWZ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GDZ1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LJI3_RAT UniProtKB/TrEMBL
  A0ABK0LSI4_RAT UniProtKB/TrEMBL
  A0ABK0LSX5_RAT UniProtKB/TrEMBL
  A6JQK5_RAT UniProtKB/TrEMBL
  G3V9U1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Agap1  ArfGAP with GTPase domain, ankyrin repeat and PH domain 1  Centg2  centaurin, gamma 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Centg2  centaurin, gamma 2   Centg2_predicted  centaurin, gamma 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Centg2_predicted  centaurin, gamma 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED