Rars1 (arginyl-tRNA synthetase 1) - Rat Genome Database

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Gene: Rars1 (arginyl-tRNA synthetase 1) Rattus norvegicus
Analyze
Symbol: Rars1
Name: arginyl-tRNA synthetase 1
RGD ID: 1309215
Description: Enables anion binding activity; arginine-tRNA ligase activity; and tRNA binding activity. Involved in arginyl-tRNA aminoacylation. Part of aminoacyl-tRNA synthetase multienzyme complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 9. Orthologous to human RARS1 (arginyl-tRNA synthetase 1); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: arginine--tRNA ligase; arginine--tRNA ligase, cytoplasmic; arginyl-tRNA synthetase; arginyl-tRNA synthetase, cytoplasmic; argRS; LOC287191; Rars
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81020,774,804 - 20,799,251 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1020,774,805 - 20,799,251 (-)EnsemblGRCr8
mRatBN7.21020,270,744 - 20,295,192 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1020,270,483 - 20,295,196 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1025,021,858 - 25,046,283 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01024,510,383 - 24,534,811 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01019,994,537 - 20,018,847 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01020,633,630 - 20,658,074 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1020,633,632 - 20,658,100 (-)Ensemblrn6Rnor6.0
Rnor_5.01020,505,807 - 20,530,334 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41020,721,170 - 20,745,484 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1019,889,464 - 19,913,910 (-)NCBICelera
RGSC_v3.11020,722,223 - 20,746,536 (-)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
actinomycin D  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
DDE  (ISO)
Di-n-octyl phthalate  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
flutamide  (EXP)
furfural  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
ivermectin  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
maneb  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methylparaben  (ISO)
nefazodone  (EXP)
Nutlin-3  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
aminoacyl-tRNA synthetase multienzyme complex  (IDA,IEA,ISO)
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO,ISS)
nucleus  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Physical and biochemical characterization of a purified arginyl-tRNA synthetase-lysyl-tRNA-synthetase complex from rat liver. Van Dang C, etal., Biochemistry. 1982 Apr 13;21(8):1959-66.
9. LysRS serves as a key signaling molecule in the immune response by regulating gene expression. Yannay-Cohen N, etal., Mol Cell. 2009 Jun 12;34(5):603-11. doi: 10.1016/j.molcel.2009.05.019.
Additional References at PubMed
PMID:8889548   PMID:10791971   PMID:12060739   PMID:12477932   PMID:12947022   PMID:18614015   PMID:19056867   PMID:19131329   PMID:19289464   PMID:19946888   PMID:22871113   PMID:23376485  
PMID:24710927   PMID:25288775   PMID:25468996  


Genomics

Comparative Map Data
Rars1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81020,774,804 - 20,799,251 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1020,774,805 - 20,799,251 (-)EnsemblGRCr8
mRatBN7.21020,270,744 - 20,295,192 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1020,270,483 - 20,295,196 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1025,021,858 - 25,046,283 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01024,510,383 - 24,534,811 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01019,994,537 - 20,018,847 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01020,633,630 - 20,658,074 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1020,633,632 - 20,658,100 (-)Ensemblrn6Rnor6.0
Rnor_5.01020,505,807 - 20,530,334 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41020,721,170 - 20,745,484 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1019,889,464 - 19,913,910 (-)NCBICelera
RGSC_v3.11020,722,223 - 20,746,536 (-)NCBI
Cytogenetic Map10q12NCBI
RARS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385168,486,471 - 168,519,301 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5168,486,447 - 168,519,306 (+)Ensemblhg38GRCh38
GRCh375167,913,476 - 167,946,306 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365167,846,041 - 167,878,889 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345167,846,040 - 167,878,885NCBI
Celera5163,948,808 - 163,981,683 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5163,012,238 - 163,045,058 (+)NCBIHuRef
CHM1_15167,346,530 - 167,379,378 (+)NCBICHM1_1
T2T-CHM13v2.05169,021,262 - 169,054,094 (+)NCBIT2T-CHM13v2.0
Rars1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,699,207 - 35,725,355 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,699,208 - 35,725,333 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381135,808,381 - 35,834,528 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,808,381 - 35,834,506 (-)Ensemblmm10GRCm38
MGSCv371135,621,883 - 35,648,030 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361135,651,806 - 35,677,929 (-)NCBIMGSCv36mm8
Celera1139,591,462 - 39,617,635 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1121.96NCBI
Rars1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540821,536,426 - 21,574,683 (+)Ensembl
ChiLan1.0NW_00495540821,536,426 - 21,574,683 (+)NCBIChiLan1.0ChiLan1.0
RARS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24163,649,100 - 163,682,236 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15161,788,645 - 161,821,781 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05163,851,644 - 163,884,787 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15170,616,819 - 170,649,655 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5170,616,819 - 170,649,655 (+)EnsemblpanPan2panpan1.1
RARS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1443,237,499 - 43,260,738 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl443,237,499 - 43,260,677 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha443,193,938 - 43,217,200 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0443,659,249 - 43,682,521 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl443,650,992 - 43,682,460 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1443,428,969 - 43,452,203 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0443,623,543 - 43,646,768 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0444,129,367 - 44,152,642 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rars1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721397,268,905 - 97,302,352 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936622884,423 - 918,650 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936622884,324 - 917,964 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RARS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1655,373,727 - 55,412,112 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11655,373,739 - 55,412,076 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21659,959,187 - 59,972,120 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RARS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12370,711,435 - 70,746,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2370,711,016 - 70,745,884 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660347,934,274 - 7,970,520 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rars1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473321,487,847 - 21,535,797 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473321,487,847 - 21,535,487 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rars1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1918,992,745 - 19,015,925 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rars1
111 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:21
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000010252
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
737823Alc12Alcohol consumption QTL 124.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101774978420796344Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat

Markers in Region
RH141338  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81020,774,929 - 20,775,631 (+)Marker Load Pipeline
mRatBN7.21020,270,869 - 20,271,571 (+)MAPPERmRatBN7.2
Rnor_6.01020,633,756 - 20,634,457NCBIRnor6.0
Rnor_5.01020,505,933 - 20,506,634UniSTSRnor5.0
RGSC_v3.41020,721,296 - 20,721,997UniSTSRGSC3.4
Celera1019,889,590 - 19,890,291UniSTS
RH 3.4 Map10240.01UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010252   ⟹   ENSRNOP00000010252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1020,774,805 - 20,799,251 (-)Ensembl
mRatBN7.2 Ensembl1020,270,483 - 20,295,196 (-)Ensembl
Rnor_6.0 Ensembl1020,633,632 - 20,658,100 (-)Ensembl
RefSeq Acc Id: NM_001105777   ⟹   NP_001099247
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,774,804 - 20,799,251 (-)NCBI
mRatBN7.21020,270,744 - 20,295,192 (-)NCBI
Rnor_6.01020,633,630 - 20,658,074 (-)NCBI
Rnor_5.01020,505,807 - 20,530,334 (-)NCBI
RGSC_v3.41020,721,170 - 20,745,484 (-)RGD
Celera1019,889,464 - 19,913,910 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099247 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI61929 (Get FASTA)   NCBI Sequence Viewer  
  EDM04095 (Get FASTA)   NCBI Sequence Viewer  
  EDM04096 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010252
  ENSRNOP00000010252.4
GenBank Protein P40329 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001099247   ⟸   NM_001105777
- UniProtKB: B1WBX8 (UniProtKB/Swiss-Prot),   P40329 (UniProtKB/Swiss-Prot),   A6HDJ0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010252   ⟸   ENSRNOT00000010252
Protein Domains
Arginyl tRNA synthetase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P40329-F1-model_v2 AlphaFold P40329 1-660 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697103
Promoter ID:EPDNEW_R7628
Type:initiation region
Name:Rars_1
Description:arginyl-tRNA synthetase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01020,658,074 - 20,658,134EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309215 AgrOrtholog
BioCyc Gene G2FUF-25537 BioCyc
BioCyc Pathway TRNA-CHARGING-PWY [tRNA charging] BioCyc
BioCyc Pathway Image TRNA-CHARGING-PWY BioCyc
Ensembl Genes ENSRNOG00000007739 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010252 ENTREZGENE
  ENSRNOT00000010252.7 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1360.70 UniProtKB/Swiss-Prot
  3.40.50.620 UniProtKB/Swiss-Prot
  Isoleucyl-tRNA Synthetase, Domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:8375237 IMAGE-MGC_LOAD
InterPro aa-tRNA-synth_I_CS UniProtKB/Swiss-Prot
  Arg-tRNA-ligase UniProtKB/Swiss-Prot
  Arg-tRNA-synth_N UniProtKB/Swiss-Prot
  Arg-tRNA-synth_N_sf UniProtKB/Swiss-Prot
  ArgRS_core UniProtKB/Swiss-Prot
  DALR_anticod-bd UniProtKB/Swiss-Prot
  Rossmann-like_a/b/a_fold UniProtKB/Swiss-Prot
  tRNAsynth_Ia_anticodon-bd UniProtKB/Swiss-Prot
KEGG Report rno:287191 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187703 IMAGE-MGC_LOAD
NCBI Gene 287191 ENTREZGENE
PANTHER ARGININE--TRNA LIGASE, CYTOPLASMIC UniProtKB/Swiss-Prot
  PTHR11956 UniProtKB/Swiss-Prot
Pfam Arg_tRNA_synt_N UniProtKB/Swiss-Prot
  DALR_1 UniProtKB/Swiss-Prot
  tRNA-synt_1d UniProtKB/Swiss-Prot
PhenoGen Rars1 PhenoGen
PRINTS TRNASYNTHARG UniProtKB/Swiss-Prot
PROSITE AA_TRNA_LIGASE_I UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007739 RatGTEx
SMART Arg_tRNA_synt_N UniProtKB/Swiss-Prot
  DALR_1 UniProtKB/Swiss-Prot
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/Swiss-Prot
  SSF47323 UniProtKB/Swiss-Prot
  SSF55190 UniProtKB/Swiss-Prot
UniProt A6HDJ0 ENTREZGENE, UniProtKB/TrEMBL
  B1WBX8 ENTREZGENE
  P40329 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B1WBX8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-09 Rars1  arginyl-tRNA synthetase 1  Rars  arginyl-tRNA synthetase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Rars  arginyl-tRNA synthetase   Rars_predicted  arginyl-tRNA synthetase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rars_predicted  arginyl-tRNA synthetase (predicted)      Symbol and Name status set to approved 70820 APPROVED