Jade2 (jade family PHD finger 2) - Rat Genome Database

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Gene: Jade2 (jade family PHD finger 2) Rattus norvegicus
Analyze
Symbol: Jade2
Name: jade family PHD finger 2
RGD ID: 1309152
Description: Predicted to enable histone H4 acetyltransferase activity and ubiquitin protein ligase activity. Predicted to contribute to histone H3K14 acetyltransferase activity. Predicted to be involved in regulation of cell cycle and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within neuron projection extension; positive regulation of neurogenesis; and protein ubiquitination. Predicted to be located in nucleoplasm. Predicted to be part of histone acetyltransferase complex. Orthologous to human JADE2 (jade family PHD finger 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase Jade-2; LOC303113; PHD finger protein 15; Phf15; protein Jade-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81036,576,187 - 36,625,129 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1036,576,187 - 36,623,532 (-)EnsemblGRCr8
mRatBN7.21036,075,239 - 36,124,210 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1036,078,917 - 36,116,984 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1040,773,970 - 40,817,631 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01040,263,950 - 40,307,612 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01035,767,677 - 35,811,341 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01037,269,132 - 37,315,638 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1037,270,183 - 37,311,625 (-)Ensemblrn6Rnor6.0
Rnor_5.01037,042,215 - 37,089,638 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41037,338,457 - 37,379,931 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1035,433,709 - 35,474,835 (-)NCBICelera
RGSC_v3.11037,344,531 - 37,389,056 (-)NCBI
Cytogenetic Map10q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-deoxy-D-glucose  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chlordecone  (ISO)
chloroprene  (ISO)
ciguatoxin CTX1B  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
Cuprizon  (EXP)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
ibuprofen  (ISO)
isoprenaline  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
melphalan  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
methylparaben  (ISO)
naled  (ISO)
niclosamide  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
pentanal  (ISO)
phenethyl isothiocyanate  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16387653   PMID:19056867   PMID:23390484   PMID:25018020  


Genomics

Comparative Map Data
Jade2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81036,576,187 - 36,625,129 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1036,576,187 - 36,623,532 (-)EnsemblGRCr8
mRatBN7.21036,075,239 - 36,124,210 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1036,078,917 - 36,116,984 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1040,773,970 - 40,817,631 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01040,263,950 - 40,307,612 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01035,767,677 - 35,811,341 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01037,269,132 - 37,315,638 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1037,270,183 - 37,311,625 (-)Ensemblrn6Rnor6.0
Rnor_5.01037,042,215 - 37,089,638 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41037,338,457 - 37,379,931 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1035,433,709 - 35,474,835 (-)NCBICelera
RGSC_v3.11037,344,531 - 37,389,056 (-)NCBI
Cytogenetic Map10q22NCBI
JADE2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385134,524,009 - 134,583,227 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5134,523,979 - 134,583,230 (+)Ensemblhg38GRCh38
GRCh375133,860,006 - 133,918,917 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365133,889,697 - 133,946,817 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345133,889,696 - 133,946,817NCBI
Celera5129,987,691 - 130,044,831 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5129,048,205 - 129,105,144 (+)NCBIHuRef
CHM1_15133,294,423 - 133,351,557 (+)NCBICHM1_1
T2T-CHM13v2.05135,049,629 - 135,108,849 (+)NCBIT2T-CHM13v2.0
Jade2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391151,704,278 - 51,749,835 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1151,704,282 - 51,748,480 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381151,813,448 - 51,859,011 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1151,813,455 - 51,857,653 (-)Ensemblmm10GRCm38
MGSCv371151,626,958 - 51,670,983 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361151,656,879 - 51,700,904 (-)NCBIMGSCv36mm8
Celera1156,380,578 - 56,416,174 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.5NCBI
Jade2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554085,687,544 - 5,723,122 (+)Ensembl
ChiLan1.0NW_0049554085,676,590 - 5,722,726 (+)NCBIChiLan1.0ChiLan1.0
JADE2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24129,824,142 - 129,881,507 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15127,963,704 - 128,021,068 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05129,929,127 - 129,986,367 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15136,076,613 - 136,133,837 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5136,087,999 - 136,129,929 (+)EnsemblpanPan2panpan1.1
JADE2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,646,487 - 22,698,436 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,648,221 - 22,698,448 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1121,391,897 - 21,443,605 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01123,448,186 - 23,499,936 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1123,449,501 - 23,499,907 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,147,768 - 22,199,512 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01122,013,922 - 22,065,838 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,655,998 - 22,707,942 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Jade2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213113,737,927 - 113,790,850 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936647740,651 - 782,810 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936647740,689 - 795,252 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JADE2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2136,788,372 - 136,832,001 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12136,686,056 - 136,832,004 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22142,285,898 - 142,446,232 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JADE2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12337,329,090 - 37,385,910 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2337,330,498 - 37,386,035 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603440,546,434 - 40,603,456 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jade2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473337,742,789 - 37,776,802 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473337,742,903 - 37,787,613 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Jade2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1934,405,731 - 34,449,753 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Jade2
498 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:43
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000043343
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103589345164140567Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103589326364653589Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103589326352293000Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102937704652699134Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000043343   ⟹   ENSRNOP00000045638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1036,578,195 - 36,615,171 (-)Ensembl
mRatBN7.2 Ensembl1036,078,917 - 36,116,984 (-)Ensembl
Rnor_6.0 Ensembl1037,270,461 - 37,311,625 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082585   ⟹   ENSRNOP00000068977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1037,270,183 - 37,305,956 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000165733   ⟹   ENSRNOP00000099332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1036,576,187 - 36,623,532 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000171455   ⟹   ENSRNOP00000103578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1036,576,187 - 36,615,838 (-)Ensembl
RefSeq Acc Id: NM_001106998   ⟹   NP_001100468
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,623,709 (-)NCBI
mRatBN7.21036,075,239 - 36,122,765 (-)NCBI
Rnor_6.01037,270,461 - 37,311,625 (-)NCBI
Rnor_5.01037,042,215 - 37,089,638 (-)NCBI
RGSC_v3.41037,338,457 - 37,379,931 (-)RGD
Celera1035,433,709 - 35,474,835 (-)RGD
Sequence:
RefSeq Acc Id: XM_006246254   ⟹   XP_006246316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,625,080 (-)NCBI
mRatBN7.21036,076,483 - 36,124,210 (-)NCBI
Rnor_6.01037,269,132 - 37,315,638 (-)NCBI
Rnor_5.01037,042,215 - 37,089,638 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006246257   ⟹   XP_006246319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,624,193 (-)NCBI
mRatBN7.21036,076,483 - 36,123,145 (-)NCBI
Rnor_6.01037,269,132 - 37,314,370 (-)NCBI
Rnor_5.01037,042,215 - 37,089,638 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006246258   ⟹   XP_006246320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,623,237 (-)NCBI
mRatBN7.21036,076,483 - 36,122,264 (-)NCBI
Rnor_6.01037,269,132 - 37,313,846 (-)NCBI
Rnor_5.01037,042,215 - 37,089,638 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006246260   ⟹   XP_006246322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,622,741 (-)NCBI
mRatBN7.21036,076,483 - 36,121,794 (-)NCBI
Rnor_6.01037,269,132 - 37,313,608 (-)NCBI
Rnor_5.01037,042,215 - 37,089,638 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597252   ⟹   XP_017452741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,623,752 (-)NCBI
mRatBN7.21036,076,483 - 36,123,145 (-)NCBI
Rnor_6.01037,269,132 - 37,314,370 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039085923   ⟹   XP_038941851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,623,237 (-)NCBI
mRatBN7.21036,076,483 - 36,122,264 (-)NCBI
RefSeq Acc Id: XM_039085924   ⟹   XP_038941852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,623,698 (-)NCBI
mRatBN7.21036,076,483 - 36,123,147 (-)NCBI
RefSeq Acc Id: XM_063268972   ⟹   XP_063125042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,625,129 (-)NCBI
RefSeq Acc Id: XM_063268973   ⟹   XP_063125043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,576,187 - 36,622,741 (-)NCBI
RefSeq Acc Id: NP_001100468   ⟸   NM_001106998
- UniProtKB: G3V9F5 (UniProtKB/TrEMBL),   A6HE78 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246316   ⟸   XM_006246254
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006246319   ⟸   XM_006246257
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006246320   ⟸   XM_006246258
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006246322   ⟸   XM_006246260
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017452741   ⟸   XM_017597252
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000045638   ⟸   ENSRNOT00000043343
Ensembl Acc Id: ENSRNOP00000068977   ⟸   ENSRNOT00000082585
RefSeq Acc Id: XP_038941852   ⟸   XM_039085924
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941851   ⟸   XM_039085923
- Peptide Label: isoform X2
- UniProtKB: G3V9F5 (UniProtKB/TrEMBL),   A6HE78 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125042   ⟸   XM_063268972
- Peptide Label: isoform X2
- UniProtKB: A6HE78 (UniProtKB/TrEMBL),   G3V9F5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125043   ⟸   XM_063268973
- Peptide Label: isoform X2
- UniProtKB: A6HE78 (UniProtKB/TrEMBL),   G3V9F5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000103578   ⟸   ENSRNOT00000171455
Ensembl Acc Id: ENSRNOP00000099332   ⟸   ENSRNOT00000165733
Protein Domains
PHD-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V9F5-F1-model_v2 AlphaFold G3V9F5 1-829 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309152 AgrOrtholog
BioCyc Gene G2FUF-25185 BioCyc
Ensembl Genes ENSRNOG00000004956 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000043343 ENTREZGENE
  ENSRNOT00000043343.5 UniProtKB/TrEMBL
  ENSRNOT00000165733 ENTREZGENE
  ENSRNOT00000165733.1 UniProtKB/TrEMBL
  ENSRNOT00000171455 ENTREZGENE
  ENSRNOT00000171455.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Enhancer_polycomb-like_N UniProtKB/TrEMBL
  EPHD UniProtKB/TrEMBL
  Histone_Mod_Regulator UniProtKB/TrEMBL
  JADE2_PHD UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:303113 UniProtKB/TrEMBL
NCBI Gene 303113 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE JADE-2 UniProtKB/TrEMBL
  PHD FINGER PROTEINS UniProtKB/TrEMBL
Pfam EPL1 UniProtKB/TrEMBL
  PHD_2 UniProtKB/TrEMBL
  zf-HC5HC2H_2 UniProtKB/TrEMBL
PhenoGen Jade2 PhenoGen
PROSITE EPHD UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004956 RatGTEx
SMART PHD UniProtKB/TrEMBL
Superfamily-SCOP FYVE_PHD_ZnF UniProtKB/TrEMBL
UniProt A0ABK0LGP6_RAT UniProtKB/TrEMBL
  A0ABK0LGU8_RAT UniProtKB/TrEMBL
  A6HE78 ENTREZGENE, UniProtKB/TrEMBL
  G3V9F5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-22 Jade2  jade family PHD finger 2  Phf15  PHD finger protein 15  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Phf15  PHD finger protein 15   Phf15_predicted  PHD finger protein 15 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Phf15_predicted  PHD finger protein 15 (predicted)      Symbol and Name status set to approved 70820 APPROVED