Cnot6l (CCR4-NOT transcription complex, subunit 6-like) - Rat Genome Database

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Gene: Cnot6l (CCR4-NOT transcription complex, subunit 6-like) Rattus norvegicus
Analyze
Symbol: Cnot6l
Name: CCR4-NOT transcription complex, subunit 6-like
RGD ID: 1309128
Description: Predicted to enable poly(A)-specific ribonuclease activity. Predicted to be involved in positive regulation of cytoplasmic mRNA processing body assembly. Predicted to act upstream of or within nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay and positive regulation of cell population proliferation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT complex. Orthologous to human CNOT6L (CCR4-NOT transcription complex subunit 6 like); PARTICIPATES IN microRNA pathway; RNA degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CCR4-NOT transcription complex subunit 6-like; LOC360917
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81413,714,475 - 13,806,481 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1413,714,475 - 13,806,481 (+)EnsemblGRCr8
mRatBN7.21413,410,499 - 13,502,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1413,411,281 - 13,498,203 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1413,379,451 - 13,466,326 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01414,679,308 - 14,766,183 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01413,395,794 - 13,482,664 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01415,059,101 - 15,148,255 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1415,059,387 - 15,146,586 (+)Ensemblrn6Rnor6.0
Rnor_5.01415,000,591 - 15,089,212 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41414,924,620 - 15,011,984 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1413,458,539 - 13,545,193 (+)NCBICelera
RGSC_v3.11414,877,885 - 15,010,870 (+)NCBI
Cytogenetic Map14p22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-butoxyethanol  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
dorsomorphin  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
gentamycin  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylphenidate  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
trichostatin A  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
CCR4-NOT complex  (IEA,ISO)
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
5. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Wahle E and Winkler GS, Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):561-70. doi: 10.1016/j.bbagrm.2013.01.003. Epub 2013 Jan 19.
Additional References at PubMed
PMID:17452450   PMID:19558367   PMID:21233283  


Genomics

Comparative Map Data
Cnot6l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81413,714,475 - 13,806,481 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1413,714,475 - 13,806,481 (+)EnsemblGRCr8
mRatBN7.21413,410,499 - 13,502,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1413,411,281 - 13,498,203 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1413,379,451 - 13,466,326 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01414,679,308 - 14,766,183 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01413,395,794 - 13,482,664 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01415,059,101 - 15,148,255 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1415,059,387 - 15,146,586 (+)Ensemblrn6Rnor6.0
Rnor_5.01415,000,591 - 15,089,212 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41414,924,620 - 15,011,984 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1413,458,539 - 13,545,193 (+)NCBICelera
RGSC_v3.11414,877,885 - 15,010,870 (+)NCBI
Cytogenetic Map14p22NCBI
CNOT6L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38477,713,387 - 77,820,269 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl477,713,387 - 77,819,615 (-)Ensemblhg38GRCh38
GRCh37478,634,541 - 78,741,423 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36478,853,565 - 78,959,568 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34479,004,337 - 79,097,701NCBI
Celera475,935,929 - 76,042,004 (-)NCBICelera
Cytogenetic Map4q21.1NCBI
HuRef474,386,458 - 74,492,461 (-)NCBIHuRef
CHM1_1478,611,478 - 78,717,345 (-)NCBICHM1_1
T2T-CHM13v2.0481,054,227 - 81,161,055 (-)NCBIT2T-CHM13v2.0
Cnot6l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39596,218,192 - 96,312,044 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl596,218,192 - 96,312,030 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38596,070,333 - 96,164,198 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl596,070,333 - 96,164,171 (-)Ensemblmm10GRCm38
MGSCv37596,504,756 - 96,591,009 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36596,315,891 - 96,402,292 (-)NCBIMGSCv36mm8
Celera593,419,034 - 93,505,443 (-)NCBICelera
Cytogenetic Map5E3NCBI
cM Map547.29NCBI
Cnot6l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554332,213,444 - 2,316,049 (-)Ensembl
ChiLan1.0NW_0049554332,206,462 - 2,290,773 (-)NCBIChiLan1.0ChiLan1.0
CNOT6L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2352,244,754 - 52,353,101 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1452,431,326 - 52,539,612 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0446,374,255 - 46,482,552 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1452,220,159 - 52,327,311 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl452,263,010 - 52,320,307 (+)EnsemblpanPan2panpan1.1
CNOT6L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1322,192,800 - 2,305,526 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl322,145,813 - 2,306,229 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3239,584,726 - 39,698,628 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0322,218,607 - 2,332,531 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl322,171,626 - 2,332,326 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1322,217,455 - 2,331,474 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0322,165,687 - 2,279,692 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03237,893,391 - 38,007,445 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cnot6l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528510,004,724 - 10,105,815 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366761,408,048 - 1,502,519 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366761,401,428 - 1,474,167 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNOT6L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl873,185,999 - 73,335,741 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1873,191,721 - 73,335,779 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2877,392,505 - 77,496,997 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CNOT6L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1726,210,368 - 26,312,938 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl726,217,371 - 26,312,567 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660374,562,902 - 4,666,026 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnot6l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475713,219,267 - 13,340,955 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475713,218,464 - 13,346,404 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cnot6l
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1118,083,319 - 8,174,256 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cnot6l
3521 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:366
Count of miRNA genes:188
Interacting mature miRNAs:261
Transcripts:ENSRNOT00000002843
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14395787818558812Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14939329839411170Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141133490630674469Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141133471628389666Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14117877928Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat

Markers in Region
D14Rat104  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81413,733,123 - 13,733,257 (+)Marker Load Pipeline
mRatBN7.21413,429,147 - 13,429,281 (+)MAPPERmRatBN7.2
Rnor_6.01415,077,242 - 15,077,375NCBIRnor6.0
Rnor_5.01415,018,327 - 15,018,460UniSTSRnor5.0
RGSC_v3.41414,942,398 - 14,942,531RGDRGSC3.4
RGSC_v3.41414,942,399 - 14,942,532UniSTSRGSC3.4
Celera1413,476,147 - 13,476,280UniSTS
RGSC_v3.11414,942,398 - 14,942,531RGD
SHRSP x BN Map146.9UniSTS
SHRSP x BN Map146.9RGD
Cytogenetic Map14p22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002843   ⟹   ENSRNOP00000002843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1413,715,253 - 13,801,950 (+)Ensembl
mRatBN7.2 Ensembl1413,411,281 - 13,498,203 (+)Ensembl
Rnor_6.0 Ensembl1415,059,387 - 15,146,586 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101961   ⟹   ENSRNOP00000085884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1413,714,475 - 13,806,481 (+)Ensembl
mRatBN7.2 Ensembl1413,436,952 - 13,498,203 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117565   ⟹   ENSRNOP00000096187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1413,732,201 - 13,806,481 (+)Ensembl
mRatBN7.2 Ensembl1413,413,054 - 13,498,203 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000136796   ⟹   ENSRNOP00000102495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1413,714,475 - 13,806,481 (+)Ensembl
RefSeq Acc Id: NM_001108355   ⟹   NP_001101825
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81413,715,257 - 13,806,481 (+)NCBI
mRatBN7.21413,411,281 - 13,502,511 (+)NCBI
Rnor_6.01415,059,387 - 15,146,586 (+)NCBI
Rnor_5.01415,000,591 - 15,089,212 (+)NCBI
RGSC_v3.41414,924,620 - 15,011,984 (+)RGD
Celera1413,458,539 - 13,545,193 (+)RGD
Sequence:
RefSeq Acc Id: NM_001414971   ⟹   NP_001401900
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81413,715,472 - 13,806,481 (+)NCBI
mRatBN7.21413,411,496 - 13,502,511 (+)NCBI
RefSeq Acc Id: NM_001415094   ⟹   NP_001402023
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81413,714,475 - 13,806,481 (+)NCBI
mRatBN7.21413,410,499 - 13,502,511 (+)NCBI
RefSeq Acc Id: XM_006250708   ⟹   XP_006250770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81413,715,188 - 13,806,481 (+)NCBI
mRatBN7.21413,411,212 - 13,502,511 (+)NCBI
Rnor_6.01415,059,287 - 15,148,255 (+)NCBI
Rnor_5.01415,000,591 - 15,089,212 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092161   ⟹   XP_038948089
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81413,715,433 - 13,806,481 (+)NCBI
mRatBN7.21413,411,464 - 13,502,511 (+)NCBI
RefSeq Acc Id: XM_039092162   ⟹   XP_038948090
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81413,715,030 - 13,806,481 (+)NCBI
mRatBN7.21413,411,058 - 13,502,511 (+)NCBI
RefSeq Acc Id: XM_039092164   ⟹   XP_038948092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81413,747,299 - 13,806,481 (+)NCBI
mRatBN7.21413,443,296 - 13,502,511 (+)NCBI
RefSeq Acc Id: XM_063273334   ⟹   XP_063129404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81413,715,885 - 13,806,481 (+)NCBI
RefSeq Acc Id: NP_001101825   ⟸   NM_001108355
- Peptide Label: isoform 1
- UniProtKB: F1M642 (UniProtKB/TrEMBL),   A6K672 (UniProtKB/TrEMBL),   A0A8I6A149 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250770   ⟸   XM_006250708
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A149 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002843   ⟸   ENSRNOT00000002843
RefSeq Acc Id: XP_038948090   ⟸   XM_039092162
- Peptide Label: isoform X2
- UniProtKB: F1M642 (UniProtKB/TrEMBL),   A6K672 (UniProtKB/TrEMBL),   A0A8I6A149 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948089   ⟸   XM_039092161
- Peptide Label: isoform X2
- UniProtKB: F1M642 (UniProtKB/TrEMBL),   A6K672 (UniProtKB/TrEMBL),   A0A8I6A149 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948092   ⟸   XM_039092164
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000085884   ⟸   ENSRNOT00000101961
Ensembl Acc Id: ENSRNOP00000096187   ⟸   ENSRNOT00000117565
RefSeq Acc Id: NP_001402023   ⟸   NM_001415094
- Peptide Label: isoform 1
- UniProtKB: F1M642 (UniProtKB/TrEMBL),   A6K672 (UniProtKB/TrEMBL),   A0A8I6A149 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401900   ⟸   NM_001414971
- Peptide Label: isoform 2
RefSeq Acc Id: XP_063129404   ⟸   XM_063273334
- Peptide Label: isoform X2
- UniProtKB: A6K672 (UniProtKB/TrEMBL),   F1M642 (UniProtKB/TrEMBL),   A0A8I6A149 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102495   ⟸   ENSRNOT00000136796
Protein Domains
Endonuclease/exonuclease/phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M642-F1-model_v2 AlphaFold F1M642 1-550 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309128 AgrOrtholog
BioCyc Gene G2FUF-16319 BioCyc
Ensembl Genes ENSRNOG00000002075 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002843 ENTREZGENE
  ENSRNOT00000002843.7 UniProtKB/TrEMBL
  ENSRNOT00000101961 ENTREZGENE
  ENSRNOT00000101961.2 UniProtKB/TrEMBL
  ENSRNOT00000117565 ENTREZGENE
  ENSRNOT00000117565.2 UniProtKB/TrEMBL
  ENSRNOT00000136796.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.10.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro CCR4/nocturin_mRNA_transcr UniProtKB/TrEMBL
  Deadenylase_CCR4b UniProtKB/TrEMBL
  Endo/exonu/phosph_ase_sf UniProtKB/TrEMBL
  Endo/exonuclease/phosphatase UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
KEGG Report rno:360917 UniProtKB/TrEMBL
NCBI Gene 360917 ENTREZGENE
PANTHER CARBON CATABOLITE REPRESSOR PROTEIN 4 UniProtKB/TrEMBL
  CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE UniProtKB/TrEMBL
Pfam Exo_endo_phos UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PhenoGen Cnot6l PhenoGen
PROSITE LRR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002075 RatGTEx
SMART LRR_TYP UniProtKB/TrEMBL
Superfamily-SCOP Exo_endo_phos UniProtKB/TrEMBL
  L domain-like UniProtKB/TrEMBL
UniProt A0A8I6A149 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AL98_RAT UniProtKB/TrEMBL
  A0ABK0LGS4_RAT UniProtKB/TrEMBL
  A6K672 ENTREZGENE, UniProtKB/TrEMBL
  F1M642 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Cnot6l  CCR4-NOT transcription complex, subunit 6-like   Cnot6l_predicted  CCR4-NOT transcription complex, subunit 6-like (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cnot6l_predicted  CCR4-NOT transcription complex, subunit 6-like (predicted)      Symbol and Name status set to approved 70820 APPROVED