Brwd1 (bromodomain and WD repeat domain containing 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Brwd1 (bromodomain and WD repeat domain containing 1) Rattus norvegicus
Analyze
Symbol: Brwd1
Name: bromodomain and WD repeat domain containing 1
RGD ID: 1309030
Description: Predicted to be involved in cytoskeleton organization; regulation of cell shape; and regulation of transcription by RNA polymerase II. Predicted to be located in axoneme and motile cilium. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Orthologous to human BRWD1 (bromodomain and WD repeat domain containing 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bromodomain and WD repeat-containing protein 1; bromodomain and WD repeat-containing protein 1-like; LOC100911399; LOC304061; WD repeat domain 9; Wdr9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81148,756,174 - 48,853,692 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1148,756,811 - 48,848,256 (-)EnsemblGRCr8
mRatBN7.21135,286,364 - 35,378,768 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,288,313 - 35,378,768 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1143,950,645 - 44,035,956 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01136,622,022 - 36,707,333 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,767,803 - 35,853,171 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01136,338,080 - 36,430,473 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1136,337,635 - 36,430,413 (-)Ensemblrn6Rnor6.0
Rnor_5.01139,868,355 - 39,961,118 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41136,303,503 - 36,385,878 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1133,077,458 - 33,183,375 (+)NCBICelera
RGSC_v3.11136,360,190 - 36,443,550 (-)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axoneme  (ISO)
motile cilium  (ISO)
nucleolus  (ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12889071   PMID:16780588   PMID:21834987  


Genomics

Comparative Map Data
Brwd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81148,756,174 - 48,853,692 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1148,756,811 - 48,848,256 (-)EnsemblGRCr8
mRatBN7.21135,286,364 - 35,378,768 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,288,313 - 35,378,768 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1143,950,645 - 44,035,956 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01136,622,022 - 36,707,333 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,767,803 - 35,853,171 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01136,338,080 - 36,430,473 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1136,337,635 - 36,430,413 (-)Ensemblrn6Rnor6.0
Rnor_5.01139,868,355 - 39,961,118 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41136,303,503 - 36,385,878 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1133,077,458 - 33,183,375 (+)NCBICelera
RGSC_v3.11136,360,190 - 36,443,550 (-)NCBI
Cytogenetic Map11q11NCBI
BRWD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382139,184,176 - 39,321,212 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2139,184,176 - 39,321,559 (-)Ensemblhg38GRCh38
GRCh372140,556,102 - 40,685,558 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362139,479,274 - 39,607,426 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342139,484,018 - 39,607,426NCBI
Celera2125,755,073 - 25,883,187 (-)NCBICelera
Cytogenetic Map21q22.2NCBI
HuRef2126,027,732 - 26,155,294 (-)NCBIHuRef
CHM1_12140,118,763 - 40,246,909 (-)NCBICHM1_1
T2T-CHM13v2.02137,568,748 - 37,705,729 (-)NCBIT2T-CHM13v2.0
Brwd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391695,793,289 - 95,883,905 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1695,793,292 - 95,883,726 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381695,992,089 - 96,082,703 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1695,992,092 - 96,082,526 (-)Ensemblmm10GRCm38
MGSCv371696,213,699 - 96,304,035 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361696,097,357 - 96,187,336 (-)NCBIMGSCv36mm8
Celera1697,066,204 - 97,156,016 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1656.77NCBI
Brwd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540738,003,386 - 38,107,958 (-)NCBIChiLan1.0ChiLan1.0
BRWD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22235,286,126 - 35,420,317 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12130,143,922 - 30,276,149 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02125,535,009 - 25,666,943 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12138,886,009 - 39,001,390 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2138,896,768 - 39,002,805 (-)EnsemblpanPan2panpan1.1
BRWD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13134,122,477 - 34,240,555 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3134,122,463 - 34,240,639 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3133,234,759 - 33,354,028 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03133,468,719 - 33,587,748 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3133,455,704 - 33,587,841 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13133,341,959 - 33,460,975 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03133,346,073 - 33,465,317 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03133,836,495 - 33,956,003 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Brwd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497133,470,876 - 33,594,248 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365003,873,615 - 3,984,523 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365003,873,570 - 3,995,725 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRWD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13202,777,305 - 202,896,509 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113202,776,040 - 202,896,545 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213212,916,565 - 212,952,696 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BRWD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1283,115,290 - 83,245,798 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl283,113,757 - 83,230,423 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605410,971,963 - 11,104,909 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brwd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474524,700,822 - 24,850,041 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Brwd1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1448,588,598 - 48,681,872 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Brwd1
716 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:66
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000002231
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11381815448818154Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
D11Got102  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,352,626 - 35,352,874 (+)MAPPERmRatBN7.2
Rnor_6.01136,404,334 - 36,404,581NCBIRnor6.0
Rnor_5.01139,934,610 - 39,934,857UniSTSRnor5.0
Rnor_5.01139,934,610 - 39,935,210UniSTSRnor5.0
RGSC_v3.41136,360,106 - 36,360,353UniSTSRGSC3.4
Cytogenetic Map11q11UniSTS
RH132723  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,361,363 - 35,361,581 (+)MAPPERmRatBN7.2
Rnor_6.01136,413,071 - 36,413,288NCBIRnor6.0
Rnor_5.01139,943,700 - 39,943,917UniSTSRnor5.0
RGSC_v3.41136,368,843 - 36,369,060UniSTSRGSC3.4
Celera1133,108,531 - 33,108,748UniSTS
Cytogenetic Map11q11UniSTS
RH143961  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,289,238 - 35,289,381 (+)MAPPERmRatBN7.2
Rnor_6.01136,340,955 - 36,341,097NCBIRnor6.0
Rnor_5.01139,871,230 - 39,871,372UniSTSRnor5.0
RGSC_v3.41136,296,727 - 36,296,869UniSTSRGSC3.4
Celera1133,180,358 - 33,180,500UniSTS
RH 3.4 Map11263.4UniSTS
Cytogenetic Map11q11UniSTS
AA944760  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,294,119 - 35,294,305 (+)MAPPERmRatBN7.2
Rnor_6.01136,345,836 - 36,346,021NCBIRnor6.0
Rnor_5.01139,876,111 - 39,876,296UniSTSRnor5.0
RGSC_v3.41136,301,608 - 36,301,793UniSTSRGSC3.4
Celera1133,175,434 - 33,175,619UniSTS
RH 3.4 Map11263.4UniSTS
Cytogenetic Map11q11UniSTS
REN19887  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,339,257 - 35,339,491 (+)MAPPERmRatBN7.2
Rnor_6.01136,390,965 - 36,391,198NCBIRnor6.0
Rnor_5.01139,921,241 - 39,921,474UniSTSRnor5.0
RGSC_v3.41136,346,737 - 36,346,970UniSTSRGSC3.4
Celera1133,130,275 - 33,130,508UniSTS
Cytogenetic Map11q11UniSTS
REN19888  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,339,467 - 35,339,674 (+)MAPPERmRatBN7.2
Rnor_6.01136,391,175 - 36,391,381NCBIRnor6.0
Rnor_5.01139,921,451 - 39,921,657UniSTSRnor5.0
RGSC_v3.41136,346,947 - 36,347,153UniSTSRGSC3.4
Celera1133,130,092 - 33,130,298UniSTS
Cytogenetic Map11q11UniSTS
ECD17717  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,378,365 - 35,378,641 (-)MAPPERmRatBN7.2
mRatBN7.21135,378,365 - 35,378,641 (+)MAPPERmRatBN7.2
Rnor_6.01136,430,071 - 36,430,346NCBIRnor6.0
Rnor_6.01139,532,009 - 39,532,284NCBIRnor6.0
Rnor_5.01142,741,543 - 42,741,818UniSTSRnor5.0
Rnor_5.01139,960,700 - 39,960,975UniSTSRnor5.0
RGSC_v3.41136,385,843 - 36,386,118UniSTSRGSC3.4
Cytogenetic Map11q11UniSTS
ECD05402  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,317,710 - 35,318,684 (+)MAPPERmRatBN7.2
Rnor_6.01136,369,422 - 36,370,395NCBIRnor6.0
Rnor_5.01139,899,698 - 39,900,671UniSTSRnor5.0
RGSC_v3.41136,325,194 - 36,326,167UniSTSRGSC3.4
Celera1133,151,080 - 33,152,053UniSTS
Cytogenetic Map11q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002231   ⟹   ENSRNOP00000002231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1148,756,811 - 48,848,256 (-)Ensembl
mRatBN7.2 Ensembl1135,288,313 - 35,378,768 (-)Ensembl
Rnor_6.0 Ensembl1136,337,635 - 36,430,413 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108092   ⟹   ENSRNOP00000076448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1148,762,892 - 48,848,256 (-)Ensembl
mRatBN7.2 Ensembl1135,293,393 - 35,378,768 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133842   ⟹   ENSRNOP00000111518
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1148,762,892 - 48,848,256 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155372   ⟹   ENSRNOP00000111509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1148,756,811 - 48,848,256 (-)Ensembl
RefSeq Acc Id: NM_001371922   ⟹   NP_001358851
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81148,762,892 - 48,848,256 (-)NCBI
mRatBN7.21135,293,393 - 35,378,768 (-)NCBI
RefSeq Acc Id: XM_006248186   ⟹   XP_006248248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81148,756,174 - 48,853,692 (-)NCBI
mRatBN7.21135,286,364 - 35,378,764 (-)NCBI
Rnor_6.01136,338,080 - 36,430,473 (-)NCBI
Rnor_5.01139,868,355 - 39,961,118 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039088408   ⟹   XP_038944336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81148,768,715 - 48,853,692 (-)NCBI
mRatBN7.21135,299,213 - 35,378,764 (-)NCBI
RefSeq Acc Id: XM_039088409   ⟹   XP_038944337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81148,771,597 - 48,853,692 (-)NCBI
mRatBN7.21135,302,098 - 35,378,764 (-)NCBI
RefSeq Acc Id: XP_006248248   ⟸   XM_006248186
- Peptide Label: isoform X1
- UniProtKB: D4AAI9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002231   ⟸   ENSRNOT00000002231
RefSeq Acc Id: NP_001358851   ⟸   NM_001371922
- UniProtKB: A0A8I5XUX5 (UniProtKB/TrEMBL),   D4AAI9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944336   ⟸   XM_039088408
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944337   ⟸   XM_039088409
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000076448   ⟸   ENSRNOT00000108092
Ensembl Acc Id: ENSRNOP00000111518   ⟸   ENSRNOT00000133842
Ensembl Acc Id: ENSRNOP00000111509   ⟸   ENSRNOT00000155372
Protein Domains
Bromo

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AAI9-F1-model_v2 AlphaFold D4AAI9 1-2303 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698093
Promoter ID:EPDNEW_R8610
Type:multiple initiation site
Name:Brwd1_1
Description:bromodomain and WD repeat domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01136,430,507 - 36,430,567EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309030 AgrOrtholog
BioCyc Gene G2FUF-21717 BioCyc
Ensembl Genes ENSRNOG00000001632 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002231.8 UniProtKB/TrEMBL
  ENSRNOT00000108092 ENTREZGENE
  ENSRNOT00000108092.2 UniProtKB/TrEMBL
  ENSRNOT00000133842.1 UniProtKB/TrEMBL
  ENSRNOT00000155372 ENTREZGENE
  ENSRNOT00000155372.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
  2.30.30.1040 UniProtKB/TrEMBL
InterPro Bromo_WD_repeat UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/TrEMBL
  BRWD/PHIP_AD UniProtKB/TrEMBL
  BRWD/PHIP_N UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene 304061 ENTREZGENE
PANTHER BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  WD REPEAT DOMAIN 9 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  BRWD1_N UniProtKB/TrEMBL
  BRWD_AD UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Brwd1 PhenoGen
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001632 RatGTEx
SMART BROMO UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP Bromodomain UniProtKB/TrEMBL
  WD40_like UniProtKB/TrEMBL
UniProt A0A8I5XUX5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LKM2_RAT UniProtKB/TrEMBL
  A0ABK0M716_RAT UniProtKB/TrEMBL
  D4AAI9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Brwd1  bromodomain and WD repeat domain containing 1  LOC100911399  bromodomain and WD repeat-containing protein 1-like  Data merged from RGD:6493193 737654 PROVISIONAL
2012-07-05 LOC100911399  bromodomain and WD repeat-containing protein 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Brwd1  bromodomain and WD repeat domain containing 1   Brwd1_predicted  bromodomain and WD repeat domain containing 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Brwd1_predicted  bromodomain and WD repeat domain containing 1 (predicted)  Wdr9_predicted  WD repeat domain 9 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Wdr9_predicted  WD repeat domain 9 (predicted)      Symbol and Name status set to approved 70820 APPROVED