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Gene: Enoph1 (enolase-phosphatase 1) Rattus norvegicus

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Symbol:

Enoph1

Name:

enolase-phosphatase 1

RGD ID:

1309016

Description:

Predicted to enable acireductone synthase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytoplasm and nucleus. Orthologous to human ENOPH1 (enolase-phosphatase 1); PARTICIPATES IN cysteine and methionine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

2,3-diketo-5-methylthio-1-phosphopentane phosphatase; E-1 enzyme; enolase-phosphatase E1; LOC305177; MASA homolog; MGC105720; RGD1309016; similar to RIKEN cDNA 2310057D15

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ENOPH1 (enolase-phosphatase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Enoph1 (enolase-phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Enoph1 (enolase-phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ENOPH1 (enolase-phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ENOPH1 (enolase-phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Enoph1 (enolase-phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ENOPH1 (enolase-phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ENOPH1 (enolase-phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Enoph1 (enolase-phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Enoph1 (enolase-phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Enoph1 (enolase-phosphatase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ENOPH1 (enolase-phosphatase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	enoph1 (enolase-phosphatase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12173	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12173	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F58H1.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F58H1.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	UTR4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	UTR4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	enoph1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	9,835,626 - 9,862,051 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	9,835,627 - 9,873,668 (-)	Ensembl				GRCr8
mRatBN7.2	14	9,531,336 - 9,557,797 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	9,531,339 - 9,569,273 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	9,503,609 - 9,529,449 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	10,803,450 - 10,829,288 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	9,500,061 - 9,525,899 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	11,172,359 - 11,198,799 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	11,172,362 - 11,198,194 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	11,116,182 - 11,142,029 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	10,833,647 - 10,859,844 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	9,632,567 - 9,658,325 (-)	NCBI		Celera
RGSC_v3.1	14	10,833,647 - 10,859,844 (-)	NCBI
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

pneumoconiosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4-hydroxyphenyl retinamide (ISO)

actinomycin D (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

chlorpyrifos (EXP,ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

folic acid (ISO)

furan (EXP)

gallic acid (ISO)

isoniazide (ISO)

ivermectin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

Nutlin-3 (ISO)

okadaic acid (ISO)

ozone (ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tetrachloromethane (EXP,ISO)

topotecan (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

tungsten (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amino acid biosynthetic process (IEA)

L-methionine salvage from methylthioadenosine (IBA,IEA,ISO,ISS)

methionine biosynthetic process (IEA)

Cellular Component

cytoplasm (IEA)

nucleus (IEA)

Molecular Function

acireductone synthase activity (IBA,IEA,ISO,ISS)

hydrolase activity (IEA)

magnesium ion binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

cysteine and methionine metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:15843022	PMID:23376485

Genomics

Comparative Map Data

Enoph1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	9,835,626 - 9,862,051 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	9,835,627 - 9,873,668 (-)	Ensembl				GRCr8
mRatBN7.2	14	9,531,336 - 9,557,797 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	9,531,339 - 9,569,273 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	9,503,609 - 9,529,449 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	10,803,450 - 10,829,288 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	9,500,061 - 9,525,899 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	11,172,359 - 11,198,799 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	11,172,362 - 11,198,194 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	11,116,182 - 11,142,029 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	10,833,647 - 10,859,844 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	9,632,567 - 9,658,325 (-)	NCBI		Celera
RGSC_v3.1	14	10,833,647 - 10,859,844 (-)	NCBI
Cytogenetic Map	14	p22	NCBI

ENOPH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	82,430,590 - 82,461,177 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	82,430,589 - 82,461,177 (+)	Ensembl			hg38	GRCh38
GRCh37	4	83,351,743 - 83,382,330 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	83,570,787 - 83,601,264 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	4	80,643,013 - 80,673,557 (+)	NCBI		Celera
Cytogenetic Map	4	q21.22	NCBI
HuRef	4	79,093,083 - 79,123,323 (+)	NCBI		HuRef
CHM1_1	4	83,328,211 - 83,358,759 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	85,760,198 - 85,790,791 (+)	NCBI		T2T-CHM13v2.0

Enoph1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	100,186,887 - 100,216,784 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	100,187,844 - 100,216,619 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	100,039,028 - 100,068,925 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	100,039,985 - 100,068,760 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	100,469,013 - 100,497,784 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	100,280,316 - 100,309,064 (+)	NCBI		MGSCv36	mm8
Celera	5	97,353,498 - 97,383,582 (+)	NCBI		Celera
Cytogenetic Map	5	E4	NCBI
cM Map	5	48.46	NCBI

Enoph1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955433	6,522,663 - 6,549,352 (+)	Ensembl
ChiLan1.0	NW_004955433	6,522,663 - 6,549,352 (+)	NCBI	ChiLan1.0	ChiLan1.0

ENOPH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	47,608,889 - 47,639,002 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	47,798,093 - 47,828,255 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	41,741,072 - 41,771,150 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	47,591,329 - 47,621,558 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	47,591,329 - 47,621,357 (-)	Ensembl			panPan2	panpan1.1

ENOPH1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	6,408,778 - 6,451,606 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	6,407,460 - 6,450,790 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	35,430,030 - 35,472,419 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	6,432,233 - 6,474,655 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	6,432,156 - 6,474,731 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	6,504,574 - 6,546,514 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	6,369,084 - 6,411,365 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	33,551,815 - 33,593,875 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Enoph1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	5,864,719 - 5,900,494 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936738	2,034,171 - 2,062,268 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936738	2,034,169 - 2,062,271 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ENOPH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	135,775,745 - 135,802,388 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	8	135,775,743 - 135,802,404 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	145,145,807 - 145,172,579 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ENOPH1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	30,810,727 - 30,843,252 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	30,810,816 - 30,844,852 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	9,372,057 - 9,406,234 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Enoph1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624757	8,456,966 - 8,488,229 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624757	8,456,021 - 8,488,262 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Enoph1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	10,286,461 - 10,313,268 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Enoph1
301 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	259
Count of miRNA genes:	155
Interacting mature miRNAs:	179
Transcripts:	ENSRNOT00000003083
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300114	Srn2	Serum renin concentration QTL 2	3.27		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	3957878	21572472	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	14	3957878	18558812	Rat
7411573	Bw139	Body weight QTL 139	4.7	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	14	1	40068101	Rat
9589814	Gluco67	Glucose level QTL 67	4.54	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	40068101	Rat
731183	Pia20	Pristane induced arthritis QTL 20	3.55		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	9393298	39411170	Rat
1331740	Bw26	Body weight QTL 26	3.028		body mass (VT:0001259)	body weight (CMO:0000012)	14	3957878	31121464	Rat
71115	Niddm15	Non-insulin dependent diabetes mellitus QTL 15	4.8		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	11334906	Rat
71117	Niddm17	Non-insulin dependent diabetes mellitus QTL 17	2.35		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	17877928	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8621398	53621398	Rat
70195	Mcs8	Mammary carcinoma susceptibility QTL 8	4.28		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	14	3957878	24886169	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41415516	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1	31893212	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8621398	53621398	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001009391	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC131411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087697	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000003083 ⟹ ENSRNOP00000003083

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	9,835,627 - 9,863,695 (-)	Ensembl
mRatBN7.2 Ensembl	14	9,531,339 - 9,557,292 (-)	Ensembl
Rnor_6.0 Ensembl	14	11,172,362 - 11,198,194 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103292 ⟹ ENSRNOP00000091321

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	9,835,627 - 9,873,668 (-)	Ensembl
mRatBN7.2 Ensembl	14	9,531,339 - 9,569,273 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000161979 ⟹ ENSRNOP00000105266

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	9,835,627 - 9,862,250 (-)	Ensembl

RefSeq Acc Id:

NM_001009391 ⟹ NP_001009391

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	9,835,626 - 9,861,459 (-)	NCBI
mRatBN7.2	14	9,531,338 - 9,557,173 (-)	NCBI
Rnor_6.0	14	11,172,361 - 11,198,194 (-)	NCBI
Rnor_5.0	14	11,116,182 - 11,142,029 (-)	NCBI
RGSC_v3.4	14	10,833,647 - 10,859,844 (-)	RGD
Celera	14	9,632,567 - 9,658,325 (-)	RGD

Sequence:

show sequence

TGCTGGGCCCTCGGGAGCTCAAAGGGTCCTGGGGCGCAGGCGGTGCTGCCCTCCTTACCAGCAA
GGCGGAGCCCGTAGTAACATCCGGCAGGGAAATGGTCGTGGTTTCTGTGCCCGCCGAAGTCACC
GTAATCCTGTTAGATATCGAAGGTACCACAACCCCGATTGCTTTCGTGAAGGACATTTTATTTC
CGTACATTAAGGAAAATGTCAAGGAGTATCTGCAGACACACTGGGAGGAGGAGGAGTGCCAGCA
GGATGTCAGCCTGCTGAGGAAGCAGGCTGAAGAAGATGCACATCTGGATGGGGCTGTCCCGATA
CCTGTGGCATCTGGTGGTGACGTGCAGCAGATGATCCAGGCTGTGGTAGACAATGTGTCCTGGC
AGATGTCTCATGACCGCAAGACCACGGCGCTCAAGCAGCTGCAGGGCCACATGTGGAAGGCGGC
GTTCACGGCTGGCCGCATGAAGGCAGAGGTCTTTGCAGATGTGGTCCCTGCCGTTAGAAGGTGG
CGGGAAGCCGGGATGAAGGTGTACATCTATTCCTCAGGGAGCGTGGAGGCGCAGAAGCTGCTCT
TCGGACATTCCACAGAGGGAGACATTCTGGAGCTCATCGATGGTCACTTTGATACCAAGATAGG
ACACAAAGTGGAAAGTGACAGTTACCGGAAGATTGCAGACAGCATCGGCTGCTCAACCAACAAC
ATCCTATTTCTCACGGATGTCACTGTAGAGGCCAGTGCTGCCGAGGAAGCAGACGTGCATGTGG
CTGTGGTGGTGAGGCCTGGCAATGCGGGGCTAACCGACGACGAGAAAACCTACTACAACCTCAT
CTCGTCCTTCAGCGAGCTCTACCTGCCGTCTACACAGAGCAAGGTCTGAGGAGAAGTCACTGTT
CCCCCTAGTGTCTAGCTTCATTCTATGTAAAAGTAACTTACTATGTGTGCACATAGGCATATGC
GAGAGTATATACGTGGCTATGCGCTCAGATTAATTTCCTTGGGCACATAATGTGAGAGAAGTAG
TCAGTTCCATGAGGCCAAATCCGTGTAAAGACACTTTGTGTGTAGACCGTAAATCTCAGTCTTG
CCAAGGCCAGAGTGTATTTGCTAAAGAAACTACAAAAATACAAATTTGTGATGTTTATCAAATT
GTTTACCAAAATGGAAAGCTAGTTTTGAGAAATTATTACCCTGAGACCATATATTTTAAAACCT
GGAAGTGCTTCGCAGGCACCCATAAGAGGAGCCCATTGCCCGTCCCAAGAGTGCGCGCCCAACC
GCCGCACTAAGACTCACGGCCCGGCCTTCACGAGACTGCGGCGTTGCTCCTGCTCAGAGCAGTT
CTGGGAAAGGCGGTTTGGTCTCAGGACGGACCGACCGGTGCTAGCAGGCGTGAGTGGAACAGCT
GAGGCCGAGGTGGGCACCCTAACCCTGTCAGTGTCAGCCTGTGTCATGGTTGCCTTTCTATGTC
TTACTGAGAATATATGTTAATGACTATTTTTTTTAAAAATGTTTTATTGAAACTGGTGTAACCC
CACAAAGAGCTCTAATGTGTAATATTTCCTCAGATGATATAAAGATGTAAATTTTATAACAGCA
TTGCTTGTCCTGATGCTGTTCTAACAGGATTTGGTGTCAGTTTCCTGTAGTTAATAATTAATAA
AAGCTTTTTCTTCTTTCAGTTTCAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017599169 ⟹ XP_017454658

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	9,845,563 - 9,862,051 (-)	NCBI
mRatBN7.2	14	9,541,277 - 9,557,797 (-)	NCBI
Rnor_6.0	14	11,182,314 - 11,198,799 (-)	NCBI

Sequence:

show sequence

AAGCGGGTCCGCGATGACCGCCTCCGTTCTGGCGTGGGCGGCGTTGGCTCAGAGGGCCTCCGCT
GCAGGATCTCCGCAGCCGGGTCCGTGCGTTCTCCCGGGCTGGCCGAGGCCGCGGCGGAGGGCGG
GGCCTGCTCGGATGACTGAAGATGTGCCAAAGCGCACGCGGTGGGCGGGGAAGGGGTCAGGTGC
CGGGGAAGGCAAGGGGCACTCACGTCCCGGGCGCGCCACTCAAGGGACTCCCGTCTGCACGCGC
CCCGGGCCTCCTGCGCGGGCTCCACCAGGCTGCGGAGGGCCGGCGCCCGCGCTCGGGGTTCCGG
GCTCCGGGCTCGGGTATTCGCTTCTTTGTTCCCGCCCACGCGAGGCCTACTTTGACGGATGGCG
TTCGCGGCTTTCCGGCGGCCAATGGGCGCGCGCGCCTTGTTTTCCCCGCCCATCGAATCCGGGG
GCCCCGCCCCTCCGACTGCCCACGTGGTCTGGGCCTGCGCCGCTCGCCTGCTCTCTGGGTGCAG
TACCTAGGGCGGCTTCCTCTGCAATTGCGGGTCCGCGCTGCCGGGCCTGTCTCCGCGCCTCTGG
TCGCTCGCTGTCGCCAGCTTCTAGATTGTTGCTGGGCCCTCGGGAGCTCAAAGGGTCCTGGGGC
GCAGGCGGTGCTGCCCTCCTTACCAGCAAGGCGGAGCCCGTAGTAACATCCGGCAGGGAAATGG
TCGTGGTTTCTGTGCCCGCCGAAGTCACCGTAATCCTGTTAGATATCGAAGGACATTTTATTTC
CGTACATTAAGGAAAATGTCAAGGAGTATCTGCAGACACACTGGGAGGAGGAGGAGTGCCAGCA
GGATGTCAGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001009391	(Get FASTA)	NCBI Sequence Viewer
	XP_017454658	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH87697	(Get FASTA)	NCBI Sequence Viewer
	EDL99583	(Get FASTA)	NCBI Sequence Viewer
	EDL99584	(Get FASTA)	NCBI Sequence Viewer
	EDL99585	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000003083.3
GenBank Protein	Q5PPH0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001009391 ⟸ NM_001009391

- UniProtKB:

Q5PPH0 (UniProtKB/Swiss-Prot), A6K613 (UniProtKB/TrEMBL), A0A8I6ADH3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVVVSVPAEVTVILLDIEGTTTPIAFVKDILFPYIKENVKEYLQTHWEEEECQQDVSLLRKQAE
EDAHLDGAVPIPVASGGDVQQMIQAVVDNVSWQMSHDRKTTALKQLQGHMWKAAFTAGRMKAEV
FADVVPAVRRWREAGMKVYIYSSGSVEAQKLLFGHSTEGDILELIDGHFDTKIGHKVESDSYRK
IADSIGCSTNNILFLTDVTVEASAAEEADVHVAVVVRPGNAGLTDDEKTYYNLISSFSELYLPS
TQSKV

hide sequence

RefSeq Acc Id:

XP_017454658 ⟸ XM_017599169

- Peptide Label:

isoform X1

- Sequence:

show sequence

MTASVLAWAALAQRASAAGSPQPGPCVLPGWPRPRRRAGPARMTEDVPKRTRWAGKGSGAGEGK
GHSRPGRATQGTPVCTRPGPPARAPPGCGGPAPALGVPGSGLGYSLLCSRPREAYFDGWRSRLS
GGQWARAPCFPRPSNPGAPPLRLPTWSGPAPLACSLGAVPRAASSAIAGPRCRACLRASGRSLS
PASRLLLGPRELKGSWGAGGAALLTSKAEPVVTSGREMVVVSVPAEVTVILLDIEGHFISVH

hide sequence

Ensembl Acc Id:

ENSRNOP00000003083 ⟸ ENSRNOT00000003083

Ensembl Acc Id:

ENSRNOP00000091321 ⟸ ENSRNOT00000103292

Ensembl Acc Id:

ENSRNOP00000105266 ⟸ ENSRNOT00000161979

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5PPH0-F1-model_v2	AlphaFold	Q5PPH0	1-261	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699197

Promoter ID:

EPDNEW_R9721

Type:

initiation region

Name:

Enoph1_1

Description:

enolase-phosphatase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	11,198,291 - 11,198,351	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309016	AgrOrtholog
BioCyc Gene	G2FUF-16390	BioCyc
Ensembl Genes	ENSRNOG00000002262	Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000003083.4	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.720.60	UniProtKB/Swiss-Prot
	3.40.50.1000	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7312419	IMAGE-MGC_LOAD
InterPro	Enolase-ppase_E1	UniProtKB/Swiss-Prot
	ENOPH1_eukaryotes	UniProtKB/Swiss-Prot
	HAD-like_sf	UniProtKB/Swiss-Prot
	HAD-SF_hydro_IA	UniProtKB/Swiss-Prot
	HAD_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:305177	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105720	IMAGE-MGC_LOAD
NCBI Gene	305177	ENTREZGENE
PANTHER	ENOLASE-PHOSPHATASE E1	UniProtKB/Swiss-Prot
	ENOLASE-PHOSPHATASE E1	UniProtKB/Swiss-Prot
Pfam	Hydrolase	UniProtKB/Swiss-Prot
PhenoGen	Enoph1	PhenoGen
RatGTEx	ENSRNOG00000002262	RatGTEx
Superfamily-SCOP	SSF56784	UniProtKB/Swiss-Prot
UniProt	A0A8I6ADH3	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LUN4_RAT	UniProtKB/TrEMBL
	A6K613	ENTREZGENE, UniProtKB/TrEMBL
	A6K614_RAT	UniProtKB/TrEMBL
	ENOPH_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-26	Enoph1	enolase-phosphatase 1	RGD1309016	similar to RIKEN cDNA 2310057D15	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1309016	similar to RIKEN cDNA 2310057D15	RGD1309016_predicted	similar to RIKEN cDNA 2310057D15 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1309016_predicted	similar to RIKEN cDNA 2310057D15 (predicted)	LOC305177_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC305177_predicted	similar to RIKEN cDNA 2310057D15 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)