Sec62 (SEC62 preprotein translocation factor) - Rat Genome Database

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Gene: Sec62 (SEC62 preprotein translocation factor) Rattus norvegicus
Analyze
Symbol: Sec62
Name: SEC62 preprotein translocation factor (Ensembl:SEC62 homolog, preprotein translocation factor)
RGD ID: 1308862
Description: Predicted to be involved in post-translational protein targeting to membrane, translocation. Predicted to act upstream of or within post-translational protein targeting to endoplasmic reticulum membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum and membrane. Orthologous to human SEC62 (SEC62 homolog, preprotein translocation factor); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ab2-292; LOC294912; SEC62 homolog; SEC62 homolog (S. cerevisiae); SEC62 homolog, preprotein translocation factor; Tloc1; translocation protein 1; translocation protein SEC62
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82114,499,317 - 114,526,705 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2114,499,317 - 114,530,321 (-)EnsemblGRCr8
mRatBN7.22112,570,810 - 112,598,198 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2112,570,819 - 112,601,814 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2119,225,136 - 119,252,553 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02117,337,700 - 117,365,117 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02112,047,361 - 112,074,776 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02116,188,736 - 116,225,510 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2116,189,862 - 116,219,750 (-)Ensemblrn6Rnor6.0
Rnor_5.02135,884,297 - 135,920,134 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42116,990,256 - 117,025,688 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2107,753,442 - 107,789,092 (-)NCBICelera
RGSC_v3.12116,934,101 - 116,970,650 (-)NCBI
Cytogenetic Map2q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chlorogenic acid  (EXP)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
erianin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
finasteride  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glucose  (EXP)
kojic acid  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
metformin  (EXP)
methyl methanesulfonate  (ISO)
miconazole  (ISO)
mifepristone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
ozone  (EXP)
paracetamol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
quercetin  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rimonabant  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
tungsten  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:22375059   PMID:29719251  


Genomics

Comparative Map Data
Sec62
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82114,499,317 - 114,526,705 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2114,499,317 - 114,530,321 (-)EnsemblGRCr8
mRatBN7.22112,570,810 - 112,598,198 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2112,570,819 - 112,601,814 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2119,225,136 - 119,252,553 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02117,337,700 - 117,365,117 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02112,047,361 - 112,074,776 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02116,188,736 - 116,225,510 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2116,189,862 - 116,219,750 (-)Ensemblrn6Rnor6.0
Rnor_5.02135,884,297 - 135,920,134 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42116,990,256 - 117,025,688 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2107,753,442 - 107,789,092 (-)NCBICelera
RGSC_v3.12116,934,101 - 116,970,650 (-)NCBI
Cytogenetic Map2q24NCBI
SEC62
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383169,966,807 - 169,998,373 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3169,966,635 - 169,998,373 (+)Ensemblhg38GRCh38
GRCh373169,684,595 - 169,716,161 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363171,167,274 - 171,198,855 (+)NCBIBuild 36Build 36hg18NCBI36
Build 343171,166,699 - 171,194,832NCBI
Celera3168,083,886 - 168,115,467 (+)NCBICelera
Cytogenetic Map3q26.2NCBI
HuRef3167,054,775 - 167,086,774 (+)NCBIHuRef
CHM1_13169,647,589 - 169,679,582 (+)NCBICHM1_1
T2T-CHM13v2.03172,751,051 - 172,783,070 (+)NCBIT2T-CHM13v2.0
Sec62
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39330,847,025 - 30,875,412 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl330,847,024 - 30,875,412 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38330,792,876 - 30,821,263 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl330,792,875 - 30,821,263 (+)Ensemblmm10GRCm38
MGSCv37330,691,798 - 30,720,185 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36330,983,714 - 31,012,101 (+)NCBIMGSCv36mm8
Celera330,705,311 - 30,733,678 (+)NCBICelera
Cytogenetic Map3A3NCBI
cM Map314.29NCBI
Sec62
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955420219,909 - 247,471 (+)Ensembl
ChiLan1.0NW_004955420219,909 - 247,471 (+)NCBIChiLan1.0ChiLan1.0
SEC62
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22167,860,147 - 167,890,588 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13167,865,070 - 167,895,311 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03166,980,212 - 167,010,455 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13175,034,119 - 175,064,902 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3175,034,739 - 175,064,902 (+)EnsemblpanPan2panpan1.1
SEC62
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13434,557,958 - 34,583,922 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3443,571,252 - 43,597,268 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03434,638,260 - 34,664,267 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3434,638,355 - 34,664,267 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13434,584,711 - 34,610,723 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03434,551,845 - 34,577,859 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03434,816,549 - 34,842,572 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sec62
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602101,173,542 - 101,199,413 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365932,421,099 - 2,448,508 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365932,423,164 - 2,448,360 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC62
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13108,660,450 - 108,691,595 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113108,660,486 - 108,688,307 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213117,326,011 - 117,348,541 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEC62
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11519,402,135 - 19,443,079 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1519,403,526 - 19,431,747 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606328,206,120 - 28,236,923 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec62
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473048,034,824 - 48,062,854 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Sec62
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13125,024,482 - 125,051,008 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sec62
183 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:103
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000012240
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)2105628029150628029Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1598865Bp296Blood pressure QTL 2962.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)282947902127947902Rat
1578772Stresp14Stress response QTL 1450.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)284056790132859658Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
2317886Alcrsp23Alcohol response QTL 232.40.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)295142371140142371Rat
2317058Aia13Adjuvant induced arthritis QTL 132.9joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)278269809123269809Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2100807373145807373Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2106869825151869825Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)293602631145807373Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
61392Bp6Blood pressure QTL 67arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)282214549127214549Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
7488933Bp368Blood pressure QTL 3680.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2104957381149957381Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1581552Pur12Proteinuria QTL 125.190.0009urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)2114032149150226270Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)2114440891159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)261051541143746880Rat

Markers in Region
RH137223  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map2682.7UniSTS
Cytogenetic Map2q24UniSTS
RH137233  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22112,571,223 - 112,571,408 (+)MAPPERmRatBN7.2
Rnor_6.02116,189,150 - 116,189,334NCBIRnor6.0
Rnor_5.02135,884,711 - 135,884,895UniSTSRnor5.0
RGSC_v3.42116,989,544 - 116,989,728UniSTSRGSC3.4
Celera2107,752,730 - 107,752,914UniSTS
RH 3.4 Map2724.0UniSTS
Cytogenetic Map2q24UniSTS
MARC_17479-17480:1016465460:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22112,590,043 - 112,591,201 (+)MAPPERmRatBN7.2
Rnor_6.02116,207,993 - 116,209,150NCBIRnor6.0
Rnor_5.02135,902,893 - 135,904,050UniSTSRnor5.0
RGSC_v3.42117,008,081 - 117,009,238UniSTSRGSC3.4
Celera2107,771,580 - 107,772,737UniSTS
Cytogenetic Map2q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012240   ⟹   ENSRNOP00000012240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2114,499,317 - 114,530,321 (-)Ensembl
mRatBN7.2 Ensembl2112,570,819 - 112,601,814 (-)Ensembl
Rnor_6.0 Ensembl2116,189,862 - 116,219,750 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098853   ⟹   ENSRNOP00000088973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2114,499,317 - 114,530,321 (-)Ensembl
mRatBN7.2 Ensembl2112,570,819 - 112,601,814 (-)Ensembl
RefSeq Acc Id: NM_001393776   ⟹   NP_001380705
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82114,499,317 - 114,526,705 (-)NCBI
mRatBN7.22112,570,810 - 112,598,198 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001380705 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH99207 (Get FASTA)   NCBI Sequence Viewer  
  AAP92608 (Get FASTA)   NCBI Sequence Viewer  
  EDM01158 (Get FASTA)   NCBI Sequence Viewer  
  EDM01159 (Get FASTA)   NCBI Sequence Viewer  
  EDM01160 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012240.4
  ENSRNOP00000088973.1
Ensembl Acc Id: ENSRNOP00000012240   ⟸   ENSRNOT00000012240
Ensembl Acc Id: ENSRNOP00000088973   ⟸   ENSRNOT00000098853
RefSeq Acc Id: NP_001380705   ⟸   NM_001393776
- UniProtKB: A6IHL1 (UniProtKB/TrEMBL),   A6IHL0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TP42-F1-model_v2 AlphaFold Q7TP42 1-605 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308862 AgrOrtholog
BioCyc Gene G2FUF-53464 BioCyc
Ensembl Genes ENSRNOG00000009057 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012240.6 UniProtKB/TrEMBL
  ENSRNOT00000098853.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7384438 IMAGE-MGC_LOAD
InterPro Sec62 UniProtKB/TrEMBL
MGC_CLONE MGC:116382 IMAGE-MGC_LOAD
NCBI Gene 294912 ENTREZGENE
PANTHER Sec62 UniProtKB/TrEMBL
  TRANSLOCATION PROTEIN SEC62 UniProtKB/TrEMBL
Pfam Sec62 UniProtKB/TrEMBL
PhenoGen Sec62 PhenoGen
RatGTEx ENSRNOG00000009057 RatGTEx
UniProt A0A8I6A8V9_RAT UniProtKB/TrEMBL
  A6IHL0 ENTREZGENE, UniProtKB/TrEMBL
  A6IHL1 ENTREZGENE, UniProtKB/TrEMBL
  Q4FZS0_RAT UniProtKB/TrEMBL
  Q7TP42_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Sec62  SEC62 preprotein translocation factor  Sec62  SEC62 homolog, preprotein translocation factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-08-11 Sec62  SEC62 homolog, preprotein translocation factor  Sec62  SEC62 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-20 Sec62  SEC62 homolog (S. cerevisiae)  Tloc1  translocation protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Tloc1  translocation protein 1  Tloc1_predicted  translocation protein 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tloc1_predicted  translocation protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED