C14h5orf52 (similar to human chromosome 5 open reading frame 52) - Rat Genome Database

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Gene: C14h5orf52 (similar to human chromosome 5 open reading frame 52) Rattus norvegicus
Analyze
Symbol: C14h5orf52
Name: similar to human chromosome 5 open reading frame 52
RGD ID: 1308775
Description: Orthologous to human C5orf52 (chromosome 5 open reading frame 52); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC305476; LOC305476; RGD1308775; similar to RIKEN cDNA 4921536K21; uncharacterized protein C5orf52 homolog; uncharacterized protein LOC305476
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81483,004,906 - 83,013,549 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1483,004,906 - 83,013,549 (-)EnsemblGRCr8
mRatBN7.21478,781,315 - 78,789,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,781,315 - 78,789,956 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1483,222,358 - 83,230,996 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,462,440 - 84,471,078 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,908,061 - 80,916,713 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01484,141,964 - 84,150,607 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1484,141,964 - 84,150,607 (-)Ensemblrn6Rnor6.0
Rnor_5.01484,825,689 - 84,834,332 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41484,547,013 - 84,555,656 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1477,693,323 - 77,701,966 (-)NCBICelera
RGSC_v3.11484,567,826 - 84,574,790 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C14h5orf52
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81483,004,906 - 83,013,549 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1483,004,906 - 83,013,549 (-)EnsemblGRCr8
mRatBN7.21478,781,315 - 78,789,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,781,315 - 78,789,956 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1483,222,358 - 83,230,996 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,462,440 - 84,471,078 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,908,061 - 80,916,713 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01484,141,964 - 84,150,607 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1484,141,964 - 84,150,607 (-)Ensemblrn6Rnor6.0
Rnor_5.01484,825,689 - 84,834,332 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41484,547,013 - 84,555,656 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1477,693,323 - 77,701,966 (-)NCBICelera
RGSC_v3.11484,567,826 - 84,574,790 (-)NCBI
Cytogenetic Map14q21NCBI
C5orf52
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385157,670,941 - 157,680,158 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5157,671,533 - 157,680,158 (+)Ensemblhg38GRCh38
GRCh375157,098,541 - 157,107,166 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365157,098,561 - 157,107,162 (+)NCBIBuild 36Build 36hg18NCBI36
Celera5153,125,154 - 153,133,754 (+)NCBICelera
Cytogenetic Map5q33.3NCBI
HuRef5152,187,174 - 152,195,776 (+)NCBIHuRef
CHM1_15156,531,279 - 156,539,880 (+)NCBICHM1_1
T2T-CHM13v2.05158,189,985 - 158,199,183 (+)NCBIT2T-CHM13v2.0
4921536K21Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,836,087 - 3,845,308 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,836,088 - 3,845,098 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38113,886,087 - 3,895,308 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,886,088 - 3,895,098 (-)Ensemblmm10GRCm38
MGSCv37113,786,091 - 3,795,129 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36113,786,091 - 3,795,101 (-)NCBIMGSCv36mm8
Celera114,379,782 - 4,388,849 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.73NCBI
LOC102005563
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554554,906,038 - 4,911,269 (+)NCBIChiLan1.0ChiLan1.0
C4H5orf52
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24152,859,773 - 152,873,569 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15150,999,320 - 151,010,537 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05153,067,760 - 153,077,098 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15159,688,552 - 159,697,137 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5159,688,552 - 159,697,137 (+)EnsemblpanPan2panpan1.1
C26H5orf52
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12623,739,657 - 23,746,132 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2623,738,729 - 23,745,963 (+)EnsemblcanFam3CanFam3.1
CUNH5orf52
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118116,663,230 - 116,671,282 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493690464,051 - 70,909 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493690463,059 - 70,989 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C14H5orf52
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,543,526 - 47,550,426 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11447,544,384 - 47,550,248 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
C23H5orf52
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12360,088,308 - 60,095,562 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603417,535,464 - 17,548,135 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH5orf52
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247477,051,451 - 7,074,307 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
C11H5orf52
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11172,899,163 - 72,905,954 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in C14h5orf52
85 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:632
Count of miRNA genes:265
Interacting mature miRNAs:322
Transcripts:ENSRNOT00000005514
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat

Markers in Region
BG376858  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21478,781,539 - 78,781,652 (+)MAPPERmRatBN7.2
Rnor_6.01484,142,189 - 84,142,301NCBIRnor6.0
Rnor_5.01484,825,914 - 84,826,026UniSTSRnor5.0
RGSC_v3.41484,547,238 - 84,547,350UniSTSRGSC3.4
Celera1477,693,548 - 77,693,660UniSTS
RH 3.4 Map15229.0UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 3 22 144 46 47 19 43 19 6 192 88 4 130 68 86 28 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000005514   ⟹   ENSRNOP00000005514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1483,004,906 - 83,013,549 (-)Ensembl
mRatBN7.2 Ensembl1478,781,315 - 78,789,956 (-)Ensembl
Rnor_6.0 Ensembl1484,141,964 - 84,150,607 (-)Ensembl
RefSeq Acc Id: NM_001107233   ⟹   NP_001100703
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81483,004,906 - 83,013,549 (-)NCBI
mRatBN7.21478,781,315 - 78,789,956 (-)NCBI
Rnor_6.01484,141,964 - 84,150,607 (-)NCBI
Rnor_5.01484,825,689 - 84,834,332 (-)NCBI
RGSC_v3.41484,547,013 - 84,555,656 (-)RGD
Celera1477,693,323 - 77,701,966 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100703 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM00194 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005514
  ENSRNOP00000005514.4
RefSeq Acc Id: NP_001100703   ⟸   NM_001107233
- UniProtKB: D3ZFB8 (UniProtKB/TrEMBL),   A6IKD0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005514   ⟸   ENSRNOT00000005514

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZFB8-F1-model_v2 AlphaFold D3ZFB8 1-167 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699430
Promoter ID:EPDNEW_R9955
Type:single initiation site
Name:RGD1308775_1
Description:similar to RIKEN cDNA 4921536K21
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01484,150,653 - 84,150,713EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308775 AgrOrtholog
BioCyc Gene G2FUF-15210 BioCyc
Ensembl Genes ENSRNOG00000004112 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005514 ENTREZGENE
  ENSRNOT00000005514.6 UniProtKB/TrEMBL
InterPro C5orf52 UniProtKB/TrEMBL
KEGG Report rno:305476 UniProtKB/TrEMBL
NCBI Gene 305476 ENTREZGENE
PANTHER PTHR35666 UniProtKB/TrEMBL
  SIMILAR TO RIKEN CDNA 4921536K21 UniProtKB/TrEMBL
Pfam DUF5528 UniProtKB/TrEMBL
PhenoGen C14h5orf52 PhenoGen
RatGTEx ENSRNOG00000004112 RatGTEx
UniProt A6IKD0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZFB8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-13 C14h5orf52  similar to human chromosome 5 open reading frame 52  RGD1308775  similar to RIKEN cDNA 4921536K21  Name and Symbol changed 629549 APPROVED
2008-04-30 RGD1308775  similar to RIKEN cDNA 4921536K21   RGD1308775_predicted  similar to RIKEN cDNA 4921536K21 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308775_predicted  similar to RIKEN cDNA 4921536K21 (predicted)  LOC305476_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC305476_predicted  similar to RIKEN cDNA 4921536K21 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL