Psmb11 (proteasome subunit beta 11) - Rat Genome Database

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Gene: Psmb11 (proteasome subunit beta 11) Rattus norvegicus
Analyze
Symbol: Psmb11
Name: proteasome subunit beta 11
RGD ID: 1308773
Description: Orthologous to human PSMB11 (proteasome subunit beta 11); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC290206; proteasome (prosome, macropain) subunit, beta type, 11; proteasome beta 11 subunit; proteasome subunit beta type-11; RGD1308773; similar to Proteasome subunit beta type 8 precursor (Proteasome component C13) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,054,747 - 32,055,666 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1532,049,118 - 32,056,299 (+)EnsemblGRCr8
mRatBN7.21528,084,736 - 28,085,655 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1529,923,839 - 29,924,758 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,071,052 - 31,071,971 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,320,796 - 29,321,715 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,267,413 - 33,273,587 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,271,015 - 33,271,920 (+)Ensemblrn6Rnor6.0
Rnor_5.01537,152,004 - 37,158,382 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41532,697,633 - 32,705,078 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1527,659,157 - 27,665,523 (+)NCBICelera
RGSC_v3.11532,717,878 - 32,719,108 (+)NCBI
Cytogenetic Map15p13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17540904  


Genomics

Comparative Map Data
Psmb11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,054,747 - 32,055,666 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1532,049,118 - 32,056,299 (+)EnsemblGRCr8
mRatBN7.21528,084,736 - 28,085,655 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1529,923,839 - 29,924,758 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,071,052 - 31,071,971 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,320,796 - 29,321,715 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,267,413 - 33,273,587 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,271,015 - 33,271,920 (+)Ensemblrn6Rnor6.0
Rnor_5.01537,152,004 - 37,158,382 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41532,697,633 - 32,705,078 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1527,659,157 - 27,665,523 (+)NCBICelera
RGSC_v3.11532,717,878 - 32,719,108 (+)NCBI
Cytogenetic Map15p13NCBI
PSMB11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,042,212 - 23,044,060 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,042,212 - 23,044,060 (+)Ensemblhg38GRCh38
GRCh371423,511,421 - 23,513,269 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,581,216 - 22,583,109 (+)NCBIBuild 36Build 36hg18NCBI36
Celera143,374,068 - 3,375,961 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,628,455 - 3,630,348 (+)NCBIHuRef
CHM1_11423,510,006 - 23,511,899 (+)NCBICHM1_1
T2T-CHM13v2.01417,242,832 - 17,244,680 (+)NCBIT2T-CHM13v2.0
Psmb11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,862,767 - 54,867,013 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,858,890 - 54,867,013 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381454,625,310 - 54,629,556 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,621,433 - 54,629,556 (+)Ensemblmm10GRCm38
MGSCv371455,244,147 - 55,248,393 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361453,579,518 - 53,583,133 (+)NCBIMGSCv36mm8
MGSCv361445,712,723 - 45,716,338 (+)NCBIMGSCv36mm8
Celera1452,413,797 - 52,417,959 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.87NCBI
Psmb11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540937,260,080 - 37,260,866 (-)NCBIChiLan1.0ChiLan1.0
PSMB11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,474,465 - 24,476,597 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,690,953 - 23,693,085 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,861,823 - 3,863,949 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,959,074 - 21,961,189 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,959,146 - 21,960,048 (+)EnsemblpanPan2panpan1.1
PSMB11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,355,239 - 3,356,505 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,303,615 - 3,305,128 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.083,462,785 - 3,464,298 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,463,081 - 3,463,929 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,154,191 - 3,155,704 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,215,429 - 3,216,942 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,477,494 - 3,479,007 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Psmb11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,107,157 - 35,109,137 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,280,042 - 1,280,923 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,279,867 - 1,281,232 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMB11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,005,612 - 76,006,703 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1776,005,609 - 76,006,728 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,356,199 - 81,357,319 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PSMB11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,410,583 - 23,413,099 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,411,557 - 23,412,459 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605923,004,528 - 23,006,421 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psmb11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,498,320 - 9,499,222 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248209,498,320 - 9,499,222 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Psmb11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11270,374,630 - 70,376,152 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Psmb11
3 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:86
Count of miRNA genes:71
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000073767
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151691152132439851Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
5 1 29 112 38 33 12 13 12 5 102 54 1 96 30 57 21 7 7

Sequence


Ensembl Acc Id: ENSRNOT00000073767   ⟹   ENSRNOP00000065348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1533,271,015 - 33,271,920 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000173206   ⟹   ENSRNOP00000107669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1532,049,118 - 32,056,299 (+)Ensembl
RefSeq Acc Id: NM_001394651   ⟹   NP_001381580
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81532,054,747 - 32,055,666 (+)NCBI
mRatBN7.21528,084,736 - 28,085,655 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001381580 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM14182 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000107669.1
Ensembl Acc Id: ENSRNOP00000065348   ⟸   ENSRNOT00000073767
RefSeq Acc Id: NP_001381580   ⟸   NM_001394651
- UniProtKB: A6KGV3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000107669   ⟸   ENSRNOT00000173206

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R7C4-F1-model_v2 AlphaFold M0R7C4 1-301 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699657
Promoter ID:EPDNEW_R10180
Type:single initiation site
Name:Psmb11_1
Description:proteasome subunit beta 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01533,271,001 - 33,271,061EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308773 AgrOrtholog
BioCyc Gene G2FUF-13790 BioCyc
Ensembl Genes ENSRNOG00000047091 Ensembl
  ENSRNOG00000072044 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000173206.1 UniProtKB/TrEMBL
Gene3D-CATH Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 UniProtKB/TrEMBL
InterPro Ntn_hydrolases_N UniProtKB/TrEMBL
  Pept_T1A_subB UniProtKB/TrEMBL
  Proteasome_bsu_CS UniProtKB/TrEMBL
  Proteasome_sua/b UniProtKB/TrEMBL
  Proteasome_suB-type UniProtKB/TrEMBL
NCBI Gene 290206 ENTREZGENE
PANTHER METALLOPROTEASE TLDD UniProtKB/TrEMBL
  PROTEASOME SUBUNIT BETA UniProtKB/TrEMBL
Pfam Proteasome UniProtKB/TrEMBL
PhenoGen Psmb11 PhenoGen
PRINTS PROTEASOME UniProtKB/TrEMBL
PROSITE PROTEASOME_BETA_1 UniProtKB/TrEMBL
  PROTEASOME_BETA_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047091 RatGTEx
  ENSRNOG00000072044 RatGTEx
Superfamily-SCOP N-terminal nucleophile aminohydrolases (Ntn hydrolases) UniProtKB/TrEMBL
UniProt A0ABK0LAS0_RAT UniProtKB/TrEMBL
  A6KGV3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-14 Psmb11  proteasome subunit beta 11  Psmb11  proteasome (prosome, macropain) subunit, beta type, 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Psmb11  proteasome (prosome, macropain) subunit, beta type, 11  RGD1308773_predicted  similar to Proteasome subunit beta type 8 precursor (Proteasome component C13) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1308773_predicted  similar to Proteasome subunit beta type 8 precursor (Proteasome component C13) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (predicted)  LOC290206_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC290206_predicted  similar to Proteasome subunit beta type 8 precursor (Proteasome component C13) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL