Ikzf2 (IKAROS family zinc finger 2) - Rat Genome Database

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Pathways
Gene: Ikzf2 (IKAROS family zinc finger 2) Rattus norvegicus
Analyze
Symbol: Ikzf2
Name: IKAROS family zinc finger 2
RGD ID: 1308686
Description: Predicted to enable DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in cochlear outer hair cell electromotile response; regulation of transcription by RNA polymerase II; and sensory perception of sound. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human IKZF2 (IKAROS family zinc finger 2); INTERACTS WITH 17beta-estradiol; alpha-Zearalanol; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC301476; Zfpn1a2; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8978,495,670 - 78,640,896 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl978,492,275 - 78,640,463 (-)EnsemblGRCr8
mRatBN7.2971,046,038 - 71,191,296 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl971,042,440 - 71,190,867 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx979,540,029 - 79,684,499 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0984,668,896 - 84,813,364 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0983,057,327 - 83,201,968 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0976,621,230 - 76,771,017 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl976,621,230 - 76,768,806 (-)Ensemblrn6Rnor6.0
Rnor_5.0976,401,302 - 76,550,479 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4968,436,877 - 68,585,545 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera968,498,043 - 68,644,480 (-)NCBICelera
RGSC_v3.1968,594,207 - 68,732,574 (-)NCBI
Cytogenetic Map9q33NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
antimonite  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
GSK-J4  (ISO)
lipopolysaccharide  (ISO)
melphalan  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
naled  (ISO)
niclosamide  (ISO)
nitrofen  (EXP)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Clinical significance of expanded Foxp3⁺ Helios⁻ regulatory T cells in patients with non-small cell lung cancer. Muto S, etal., Int J Oncol. 2015 Dec;47(6):2082-90. doi: 10.3892/ijo.2015.3196. Epub 2015 Oct 12.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9560339  


Genomics

Comparative Map Data
Ikzf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8978,495,670 - 78,640,896 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl978,492,275 - 78,640,463 (-)EnsemblGRCr8
mRatBN7.2971,046,038 - 71,191,296 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl971,042,440 - 71,190,867 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx979,540,029 - 79,684,499 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0984,668,896 - 84,813,364 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0983,057,327 - 83,201,968 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0976,621,230 - 76,771,017 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl976,621,230 - 76,768,806 (-)Ensemblrn6Rnor6.0
Rnor_5.0976,401,302 - 76,550,479 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4968,436,877 - 68,585,545 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera968,498,043 - 68,644,480 (-)NCBICelera
RGSC_v3.1968,594,207 - 68,732,574 (-)NCBI
Cytogenetic Map9q33NCBI
IKZF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382212,999,698 - 213,152,456 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2212,999,691 - 213,152,427 (-)Ensemblhg38GRCh38
GRCh372213,864,422 - 214,017,180 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362213,572,653 - 213,724,578 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342213,696,849 - 213,840,564NCBI
Celera2207,628,331 - 207,780,208 (-)NCBICelera
Cytogenetic Map2q34NCBI
HuRef2205,713,880 - 205,865,875 (-)NCBIHuRef
CHM1_12213,870,566 - 214,022,519 (-)NCBICHM1_1
T2T-CHM13v2.02213,416,757 - 213,633,302 (-)NCBIT2T-CHM13v2.0
Ikzf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39169,570,382 - 69,726,510 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl169,570,373 - 69,726,404 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38169,531,207 - 69,687,351 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl169,531,214 - 69,687,245 (-)Ensemblmm10GRCm38
MGSCv37169,577,781 - 69,732,534 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36169,470,598 - 69,619,029 (-)NCBIMGSCv36mm8
Celera170,088,227 - 70,243,344 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map134.9NCBI
Ikzf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554572,608,894 - 2,755,455 (+)Ensembl
ChiLan1.0NW_0049554572,608,892 - 2,763,036 (+)NCBIChiLan1.0ChiLan1.0
IKZF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213115,622,820 - 115,773,953 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B115,639,394 - 115,790,868 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B100,255,430 - 100,407,395 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B218,731,828 - 218,882,087 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B218,737,506 - 218,882,087 (-)EnsemblpanPan2panpan1.1
IKZF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13720,508,647 - 20,662,549 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3720,516,239 - 20,661,298 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3721,387,600 - 21,542,297 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03720,500,779 - 20,655,655 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3720,504,445 - 20,653,695 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13720,407,319 - 20,561,909 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03720,355,896 - 20,510,382 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03720,373,416 - 20,528,153 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ikzf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303168,945,604 - 169,100,732 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365863,525,933 - 3,674,061 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365863,522,614 - 3,676,070 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IKZF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15115,512,179 - 115,677,374 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115115,512,160 - 115,677,503 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215127,875,632 - 127,901,288 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IKZF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11098,750,782 - 98,909,061 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1098,759,037 - 98,909,007 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040100,492,927 - 100,649,376 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ikzf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247653,017,571 - 3,164,136 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247653,016,569 - 3,171,443 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ikzf2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14143,297,280 - 143,434,990 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ikzf2
730 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:41
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000057849
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat

Markers in Region
D9Rat10  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8978,547,769 - 78,547,958 (+)Marker Load Pipeline
mRatBN7.2971,098,157 - 71,098,346 (+)MAPPERmRatBN7.2
Rnor_6.0976,677,448 - 76,677,636NCBIRnor6.0
Rnor_5.0976,457,337 - 76,457,525UniSTSRnor5.0
RGSC_v3.4968,492,870 - 68,493,058UniSTSRGSC3.4
RGSC_v3.4968,492,869 - 68,493,058RGDRGSC3.4
Celera968,553,309 - 68,553,497UniSTS
RGSC_v3.1968,639,852 - 68,640,040RGD
RH 3.4 Map9647.6RGD
RH 3.4 Map9647.6UniSTS
RH 2.0 Map9669.8RGD
SHRSP x BN Map948.9598RGD
FHH x ACI Map945.67RGD
Cytogenetic Map9q32UniSTS
D9Rat175  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8978,612,980 - 78,613,111 (+)Marker Load Pipeline
mRatBN7.2971,163,378 - 71,163,509 (+)MAPPERmRatBN7.2
Rnor_6.0976,742,828 - 76,742,958NCBIRnor6.0
Rnor_5.0976,522,717 - 76,522,847UniSTSRnor5.0
RGSC_v3.4968,558,159 - 68,558,289UniSTSRGSC3.4
RGSC_v3.4968,558,158 - 68,558,289RGDRGSC3.4
Celera968,618,477 - 68,618,607UniSTS
RGSC_v3.1968,705,140 - 68,705,271RGD
SHRSP x BN Map947.7998UniSTS
SHRSP x BN Map947.7998RGD
Cytogenetic Map9q32UniSTS
D9Rat172  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2971,075,798 - 71,076,004 (+)MAPPERmRatBN7.2
Rnor_6.0976,655,112 - 76,655,317NCBIRnor6.0
Rnor_5.0976,434,987 - 76,435,192UniSTSRnor5.0
RGSC_v3.4968,470,072 - 68,470,279RGDRGSC3.4
RGSC_v3.4968,470,073 - 68,470,278UniSTSRGSC3.4
Celera968,530,938 - 68,531,143UniSTS
RGSC_v3.1968,616,742 - 68,617,414RGD
SHRSP x BN Map948.9699UniSTS
SHRSP x BN Map948.9699RGD
Cytogenetic Map9q32UniSTS
D9Got78  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2971,107,162 - 71,107,380 (+)MAPPERmRatBN7.2
Rnor_6.0976,686,451 - 76,686,668NCBIRnor6.0
Rnor_5.0976,466,340 - 76,466,557UniSTSRnor5.0
RGSC_v3.4968,501,872 - 68,502,090RGDRGSC3.4
RGSC_v3.4968,501,873 - 68,502,090UniSTSRGSC3.4
Celera968,562,312 - 68,562,529UniSTS
RGSC_v3.1968,648,855 - 68,649,072RGD
RH 3.4 Map9647.6UniSTS
RH 3.4 Map9647.6RGD
RH 2.0 Map9667.4RGD
Cytogenetic Map9q32UniSTS
RH134261  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2971,046,185 - 71,046,384 (+)MAPPERmRatBN7.2
Rnor_6.0976,624,976 - 76,625,174NCBIRnor6.0
Rnor_5.0976,405,048 - 76,405,246UniSTSRnor5.0
RGSC_v3.4968,440,623 - 68,440,821UniSTSRGSC3.4
Celera968,501,789 - 68,501,987UniSTS
RH 3.4 Map9647.7UniSTS
Cytogenetic Map9q32UniSTS
RH140802  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2971,186,497 - 71,186,700 (+)MAPPERmRatBN7.2
Rnor_6.0976,765,944 - 76,766,146NCBIRnor6.0
Rnor_5.0976,545,833 - 76,546,035UniSTSRnor5.0
RGSC_v3.4968,582,682 - 68,582,884UniSTSRGSC3.4
Celera968,641,614 - 68,641,816UniSTS
RH 3.4 Map9647.7UniSTS
Cytogenetic Map9q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 84 83 52 92 52 6 349 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000057849   ⟹   ENSRNOP00000054658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl978,492,275 - 78,640,359 (-)Ensembl
mRatBN7.2 Ensembl971,042,440 - 71,189,361 (-)Ensembl
Rnor_6.0 Ensembl976,621,230 - 76,768,806 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087779   ⟹   ENSRNOP00000069412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl978,503,137 - 78,640,359 (-)Ensembl
mRatBN7.2 Ensembl971,053,521 - 71,189,361 (-)Ensembl
Rnor_6.0 Ensembl976,632,112 - 76,768,770 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102104   ⟹   ENSRNOP00000087415
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl971,052,102 - 71,189,361 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116112   ⟹   ENSRNOP00000093923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl971,052,102 - 71,190,867 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116708   ⟹   ENSRNOP00000091144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl971,052,102 - 71,188,609 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118462   ⟹   ENSRNOP00000081679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl971,052,693 - 71,186,740 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119011   ⟹   ENSRNOP00000079523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl971,052,102 - 71,189,488 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120140   ⟹   ENSRNOP00000091675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl971,052,102 - 71,189,361 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000121577   ⟹   ENSRNOP00000111682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl978,495,676 - 78,640,463 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155133   ⟹   ENSRNOP00000109346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl978,495,676 - 78,640,359 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000160705   ⟹   ENSRNOP00000101201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl978,495,676 - 78,640,359 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000166250   ⟹   ENSRNOP00000101619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl978,495,676 - 78,640,359 (-)Ensembl
RefSeq Acc Id: NM_001106916   ⟹   NP_001100386
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,676 - 78,640,359 (-)NCBI
mRatBN7.2971,046,060 - 71,190,759 (-)NCBI
Rnor_6.0976,621,230 - 76,768,806 (-)NCBI
Rnor_5.0976,401,302 - 76,550,479 (-)NCBI
RGSC_v3.4968,436,877 - 68,585,545 (-)RGD
Celera968,498,043 - 68,644,480 (-)RGD
Sequence:
RefSeq Acc Id: XM_006245119   ⟹   XP_006245181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,367 (-)NCBI
mRatBN7.2971,046,038 - 71,190,773 (-)NCBI
Rnor_6.0976,625,693 - 76,770,279 (-)NCBI
Rnor_5.0976,401,302 - 76,550,479 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245120   ⟹   XP_006245182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,896 (-)NCBI
mRatBN7.2971,046,038 - 71,191,296 (-)NCBI
Rnor_6.0976,625,693 - 76,771,017 (-)NCBI
Rnor_5.0976,401,302 - 76,550,479 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245121   ⟹   XP_006245183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,638,376 (-)NCBI
mRatBN7.2971,046,038 - 71,188,800 (-)NCBI
Rnor_6.0976,625,693 - 76,768,284 (-)NCBI
Rnor_5.0976,401,302 - 76,550,479 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767219   ⟹   XP_008765441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,376 (-)NCBI
mRatBN7.2971,046,038 - 71,190,777 (-)NCBI
Rnor_6.0976,625,693 - 76,768,828 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083325   ⟹   XP_038939253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,367 (-)NCBI
mRatBN7.2971,046,038 - 71,190,775 (-)NCBI
RefSeq Acc Id: XM_063266954   ⟹   XP_063123024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,369 (-)NCBI
RefSeq Acc Id: XM_063266955   ⟹   XP_063123025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,884 (-)NCBI
RefSeq Acc Id: XM_063266956   ⟹   XP_063123026
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,367 (-)NCBI
RefSeq Acc Id: XM_063266957   ⟹   XP_063123027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,896 (-)NCBI
RefSeq Acc Id: XM_063266958   ⟹   XP_063123028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,638,377 (-)NCBI
RefSeq Acc Id: XM_063266959   ⟹   XP_063123029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,374 (-)NCBI
RefSeq Acc Id: XM_063266961   ⟹   XP_063123031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8978,495,670 - 78,640,369 (-)NCBI
RefSeq Acc Id: NP_001100386   ⟸   NM_001106916
- UniProtKB: A6KFF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245182   ⟸   XM_006245120
- Peptide Label: isoform X4
- UniProtKB: A6KFF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245181   ⟸   XM_006245119
- Peptide Label: isoform X4
- UniProtKB: A6KFF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245183   ⟸   XM_006245121
- Peptide Label: isoform X4
- UniProtKB: A6KFF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765441   ⟸   XM_008767219
- Peptide Label: isoform X6
- UniProtKB: A6KFF3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000054658   ⟸   ENSRNOT00000057849
Ensembl Acc Id: ENSRNOP00000069412   ⟸   ENSRNOT00000087779
RefSeq Acc Id: XP_038939253   ⟸   XM_039083325
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZMW5 (UniProtKB/TrEMBL),   A6KFF3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093923   ⟸   ENSRNOT00000116112
Ensembl Acc Id: ENSRNOP00000091675   ⟸   ENSRNOT00000120140
Ensembl Acc Id: ENSRNOP00000087415   ⟸   ENSRNOT00000102104
Ensembl Acc Id: ENSRNOP00000091144   ⟸   ENSRNOT00000116708
Ensembl Acc Id: ENSRNOP00000081679   ⟸   ENSRNOT00000118462
Ensembl Acc Id: ENSRNOP00000079523   ⟸   ENSRNOT00000119011
RefSeq Acc Id: XP_063123027   ⟸   XM_063266957
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AGQ5 (UniProtKB/TrEMBL),   A6KFF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123025   ⟸   XM_063266955
- Peptide Label: isoform X1
- UniProtKB: A6KFF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123029   ⟸   XM_063266959
- Peptide Label: isoform X5
- UniProtKB: A6KFF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123031   ⟸   XM_063266961
- Peptide Label: isoform X7
- UniProtKB: A6KFF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123024   ⟸   XM_063266954
- Peptide Label: isoform X1
- UniProtKB: A6KFF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123026   ⟸   XM_063266956
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AGQ5 (UniProtKB/TrEMBL),   A6KFF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123028   ⟸   XM_063266958
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AGQ5 (UniProtKB/TrEMBL),   A6KFF3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111682   ⟸   ENSRNOT00000121577
Ensembl Acc Id: ENSRNOP00000101619   ⟸   ENSRNOT00000166250
Ensembl Acc Id: ENSRNOP00000109346   ⟸   ENSRNOT00000155133
Ensembl Acc Id: ENSRNOP00000101201   ⟸   ENSRNOT00000160705
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVA9-F1-model_v2 AlphaFold A0A0G2JVA9 1-541 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308686 AgrOrtholog
BioCyc Gene G2FUF-27265 BioCyc
Ensembl Genes ENSRNOG00000027430 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057849.5 UniProtKB/TrEMBL
  ENSRNOT00000087779.3 UniProtKB/TrEMBL
  ENSRNOT00000121577 ENTREZGENE
  ENSRNOT00000121577.1 UniProtKB/TrEMBL
  ENSRNOT00000155133 ENTREZGENE
  ENSRNOT00000155133.1 UniProtKB/TrEMBL
  ENSRNOT00000160705 ENTREZGENE
  ENSRNOT00000160705.1 UniProtKB/TrEMBL
  ENSRNOT00000166250.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Ikaros_C2H2-ZF UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:301476 UniProtKB/TrEMBL
NCBI Gene 301476 ENTREZGENE
PANTHER ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN HELIOS UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Ikzf2 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027430 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A0G2JVA9_RAT UniProtKB/TrEMBL
  A0A8I5ZMW5 ENTREZGENE
  A0A8I6AGQ5 ENTREZGENE
  A0ABK0LFH9_RAT UniProtKB/TrEMBL
  A0ABK0LIN9_RAT UniProtKB/TrEMBL
  A0ABK0LT64_RAT UniProtKB/TrEMBL
  A0ABK0M501_RAT UniProtKB/TrEMBL
  A6KFF1_RAT UniProtKB/TrEMBL
  A6KFF3 ENTREZGENE, UniProtKB/TrEMBL
  D4A7Y7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-03 Ikzf2  IKAROS family zinc finger 2  Zfpn1a2_predicted  zinc finger protein, subfamily 1A, 2 (Helios) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Zfpn1a2_predicted  zinc finger protein, subfamily 1A, 2 (Helios) (predicted)      Symbol and Name status set to approved 70820 APPROVED