Dcaf8 (DDB1 and CUL4 associated factor 8) - Rat Genome Database

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Pathways
Gene: Dcaf8 (DDB1 and CUL4 associated factor 8) Rattus norvegicus
Analyze
Symbol: Dcaf8
Name: DDB1 and CUL4 associated factor 8
RGD ID: 1308513
Description: Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within myotube cell development. Predicted to be located in nucleus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in giant axonal neuropathy 2. Orthologous to human DCAF8 (DDB1 and CUL4 associated factor 8); INTERACTS WITH 17beta-estradiol; amiodarone; amitriptyline.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DDB1- and CUL4-associated factor 8; LOC364050; RGD1308513; similar to expressed sequence AA408877; WD repeat domain 42A; WD repeat-containing protein 42A; Wdr42a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81387,141,940 - 87,199,859 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1387,142,525 - 87,202,099 (+)EnsemblGRCr8
mRatBN7.21384,609,838 - 84,667,025 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,610,248 - 84,669,726 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1387,113,615 - 87,159,972 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01388,513,873 - 88,560,232 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01385,698,680 - 85,745,009 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01390,532,153 - 90,587,542 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,532,326 - 90,591,796 (+)Ensemblrn6Rnor6.0
Rnor_5.01395,053,210 - 95,114,044 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41388,029,285 - 88,186,506 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1384,221,681 - 84,268,071 (+)NCBICelera
RGSC_v3.11388,218,174 - 88,375,388 (+)NCBI
Cytogenetic Map13q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Cul4-RING E3 ubiquitin ligase complex  (IBA,IEA,ISO,ISS)
cytoplasm  (IBA,IEA,ISO,ISS)
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16949367   PMID:22500989  


Genomics

Comparative Map Data
Dcaf8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81387,141,940 - 87,199,859 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1387,142,525 - 87,202,099 (+)EnsemblGRCr8
mRatBN7.21384,609,838 - 84,667,025 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,610,248 - 84,669,726 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1387,113,615 - 87,159,972 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01388,513,873 - 88,560,232 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01385,698,680 - 85,745,009 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01390,532,153 - 90,587,542 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,532,326 - 90,591,796 (+)Ensemblrn6Rnor6.0
Rnor_5.01395,053,210 - 95,114,044 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41388,029,285 - 88,186,506 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1384,221,681 - 84,268,071 (+)NCBICelera
RGSC_v3.11388,218,174 - 88,375,388 (+)NCBI
Cytogenetic Map13q24NCBI
DCAF8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,215,720 - 160,262,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1160,215,715 - 160,263,388 (-)Ensemblhg38GRCh38
GRCh371160,185,510 - 160,232,339 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361158,452,129 - 158,498,603 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341156,998,577 - 157,045,052NCBI
Celera1133,254,265 - 133,301,114 (-)NCBICelera
Cytogenetic Map1q23.2NCBI
HuRef1131,542,143 - 131,588,999 (-)NCBIHuRef
CHM1_11161,580,851 - 161,627,695 (-)NCBICHM1_1
T2T-CHM13v2.01159,352,793 - 159,399,623 (-)NCBIT2T-CHM13v2.0
Dcaf8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,975,574 - 172,023,959 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,975,651 - 172,024,572 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381172,148,015 - 172,196,393 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,148,084 - 172,197,005 (+)Ensemblmm10GRCm38
MGSCv371174,078,146 - 174,126,524 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361173,984,817 - 174,032,141 (+)NCBIMGSCv36mm8
Celera1175,002,206 - 175,052,357 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.54NCBI
Dcaf8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546811,991,779 - 12,036,835 (-)Ensembl
ChiLan1.0NW_00495546811,991,779 - 12,037,541 (-)NCBIChiLan1.0ChiLan1.0
DCAF8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2189,589,411 - 89,636,303 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1189,329,425 - 89,375,254 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01135,569,736 - 135,616,614 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11139,490,846 - 139,537,816 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1139,490,069 - 139,537,572 (-)EnsemblpanPan2panpan1.1
DCAF8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,959,228 - 22,001,388 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,959,254 - 21,999,677 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3822,032,410 - 22,074,461 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03822,075,704 - 22,117,837 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3822,075,689 - 22,117,833 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,980,526 - 22,022,632 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03822,376,883 - 22,418,955 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,786,523 - 22,828,634 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dcaf8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050586,338,513 - 6,385,709 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936740387,469 - 413,961 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936740368,795 - 415,997 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCAF8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl490,214,973 - 90,261,737 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1490,214,916 - 90,263,259 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2498,104,312 - 98,150,952 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DCAF8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1203,685,340 - 3,731,323 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl203,703,641 - 3,729,479 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660382,742,671 - 2,788,965 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcaf8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624794996,012 - 1,041,301 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dcaf8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11051,262,227 - 51,309,062 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dcaf8
364 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:78
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000008944
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)137161080489333251Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)137161080489333251Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)137161080489333251Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
RH127477  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,530,552 - 84,530,739 (+)MAPPERmRatBN7.2
Rnor_6.01390,451,157 - 90,451,343NCBIRnor6.0
Rnor_5.01394,974,121 - 94,974,307UniSTSRnor5.0
RGSC_v3.41388,060,595 - 88,060,781UniSTSRGSC3.4
Celera1384,142,330 - 84,142,516UniSTS
RH 3.4 Map13551.9UniSTS
Cytogenetic Map13q24UniSTS
RH128723  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01870,740,618 - 70,740,811NCBIRnor5.0
Rnor_5.01870,864,224 - 70,864,417NCBIRnor5.0
Rnor_5.01395,044,254 - 95,044,447NCBIRnor5.0
RGSC_v3.41872,488,777 - 72,488,969UniSTSRGSC3.4
RGSC_v3.41388,131,422 - 88,131,614UniSTSRGSC3.4
Celera1867,891,233 - 67,891,425UniSTS
Celera1384,212,607 - 84,212,799UniSTS
Cytogenetic Map13q24UniSTS
RH134414  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,586,548 - 84,586,741 (+)MAPPERmRatBN7.2
Rnor_6.01390,508,564 - 90,508,756NCBIRnor6.0
Rnor_5.01395,029,700 - 95,029,892UniSTSRnor5.0
RGSC_v3.41388,116,690 - 88,116,882UniSTSRGSC3.4
Celera1384,198,182 - 84,198,374UniSTS
RH 3.4 Map13553.5UniSTS
Cytogenetic Map13q24UniSTS
BF399606  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,650,226 - 84,650,381 (+)MAPPERmRatBN7.2
Rnor_6.01390,572,256 - 90,572,410NCBIRnor6.0
Rnor_5.01395,093,361 - 95,093,515UniSTSRnor5.0
RGSC_v3.41388,180,086 - 88,180,240UniSTSRGSC3.4
Celera1384,261,651 - 84,261,805UniSTS
RH 3.4 Map13553.0UniSTS
Cytogenetic Map13q24UniSTS
AU046984  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,637,602 - 84,637,861 (+)MAPPERmRatBN7.2
Rnor_6.01390,559,635 - 90,559,891NCBIRnor6.0
Rnor_5.01395,080,737 - 95,080,993UniSTSRnor5.0
RGSC_v3.41388,038,114 - 88,038,370UniSTSRGSC3.4
Celera1384,249,045 - 84,249,301UniSTS
Cytogenetic Map13q24UniSTS
RH134885  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,650,914 - 84,651,115 (+)MAPPERmRatBN7.2
Rnor_6.01390,572,944 - 90,573,144NCBIRnor6.0
Rnor_5.01395,094,049 - 95,094,249UniSTSRnor5.0
RGSC_v3.41388,180,774 - 88,180,974UniSTSRGSC3.4
Celera1384,262,339 - 84,262,539UniSTS
RH 3.4 Map13564.4UniSTS
Cytogenetic Map13q24UniSTS
RH135139  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01870,740,228 - 70,740,447NCBIRnor5.0
Rnor_5.01870,863,834 - 70,864,053NCBIRnor5.0
Rnor_5.01395,044,618 - 95,044,837NCBIRnor5.0
RGSC_v3.41872,488,387 - 72,488,605UniSTSRGSC3.4
RGSC_v3.41388,131,786 - 88,132,004UniSTSRGSC3.4
Celera1867,891,597 - 67,891,815UniSTS
Celera1384,212,971 - 84,213,189UniSTS
Cytogenetic Map13q24UniSTS
RH140256  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,530,607 - 84,530,827 (+)MAPPERmRatBN7.2
Rnor_6.01390,451,212 - 90,451,431NCBIRnor6.0
Rnor_5.01394,974,176 - 94,974,395UniSTSRnor5.0
RGSC_v3.41388,060,650 - 88,060,869UniSTSRGSC3.4
Celera1384,142,385 - 84,142,604UniSTS
RH 3.4 Map13552.5UniSTS
Cytogenetic Map13q24UniSTS
BF409555  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,649,239 - 84,649,377 (+)MAPPERmRatBN7.2
Rnor_6.01390,571,269 - 90,571,406NCBIRnor6.0
Rnor_5.01395,092,374 - 95,092,511UniSTSRnor5.0
RGSC_v3.41388,179,099 - 88,179,236UniSTSRGSC3.4
Celera1384,260,664 - 84,260,801UniSTS
RH 3.4 Map13554.4UniSTS
Cytogenetic Map13q24UniSTS
G42043  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,654,031 - 84,654,237 (+)MAPPERmRatBN7.2
Rnor_6.01390,576,061 - 90,576,266NCBIRnor6.0
Rnor_5.01395,097,166 - 95,097,371UniSTSRnor5.0
RGSC_v3.41388,183,891 - 88,184,096UniSTSRGSC3.4
Celera1384,265,456 - 84,265,661UniSTS
Cytogenetic Map13q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001014231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010056926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC095300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000008944   ⟹   ENSRNOP00000008944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1387,143,400 - 87,189,872 (+)Ensembl
mRatBN7.2 Ensembl1384,611,327 - 84,657,413 (+)Ensembl
Rnor_6.0 Ensembl1390,532,326 - 90,578,674 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082469   ⟹   ENSRNOP00000070721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1387,142,603 - 87,202,099 (+)Ensembl
mRatBN7.2 Ensembl1384,610,248 - 84,669,726 (+)Ensembl
Rnor_6.0 Ensembl1390,533,365 - 90,591,796 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101398   ⟹   ENSRNOP00000095537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1387,142,525 - 87,189,871 (+)Ensembl
mRatBN7.2 Ensembl1384,610,248 - 84,657,402 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104949   ⟹   ENSRNOP00000083449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1387,166,441 - 87,189,873 (+)Ensembl
mRatBN7.2 Ensembl1384,611,093 - 84,657,498 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000126224   ⟹   ENSRNOP00000111979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1387,142,603 - 87,190,792 (+)Ensembl
RefSeq Acc Id: NM_001014231   ⟹   NP_001014253
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81387,142,671 - 87,189,021 (+)NCBI
mRatBN7.21384,610,294 - 84,656,647 (+)NCBI
Rnor_6.01390,532,326 - 90,578,676 (+)NCBI
Rnor_5.01395,053,210 - 95,114,044 (+)NCBI
RGSC_v3.41388,029,285 - 88,186,506 (+)RGD
Celera1384,221,681 - 84,268,071 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250297   ⟹   XP_006250359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81387,141,940 - 87,189,873 (+)NCBI
mRatBN7.21384,609,838 - 84,657,501 (+)NCBI
Rnor_6.01390,532,153 - 90,579,530 (+)NCBI
Rnor_5.01395,053,210 - 95,114,044 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250298   ⟹   XP_006250360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81387,143,568 - 87,189,873 (+)NCBI
mRatBN7.21384,611,191 - 84,657,501 (+)NCBI
Rnor_6.01390,532,473 - 90,579,530 (+)NCBI
Rnor_5.01395,053,210 - 95,114,044 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063272520   ⟹   XP_063128590
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81387,142,608 - 87,199,859 (+)NCBI
RefSeq Acc Id: XM_063272522   ⟹   XP_063128592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81387,142,608 - 87,199,859 (+)NCBI
RefSeq Acc Id: XR_010056926
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81387,142,608 - 87,186,656 (+)NCBI
RefSeq Acc Id: NP_001014253   ⟸   NM_001014231
- UniProtKB: Q5U2M6 (UniProtKB/Swiss-Prot),   A6JG32 (UniProtKB/TrEMBL),   A0A8L2Q3J7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250359   ⟸   XM_006250297
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006250360   ⟸   XM_006250298
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000008944   ⟸   ENSRNOT00000008944
Ensembl Acc Id: ENSRNOP00000070721   ⟸   ENSRNOT00000082469
Ensembl Acc Id: ENSRNOP00000083449   ⟸   ENSRNOT00000104949
Ensembl Acc Id: ENSRNOP00000095537   ⟸   ENSRNOT00000101398
RefSeq Acc Id: XP_063128592   ⟸   XM_063272522
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063128590   ⟸   XM_063272520
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000111979   ⟸   ENSRNOT00000126224

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2M6-F1-model_v2 AlphaFold Q5U2M6 1-591 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699020
Promoter ID:EPDNEW_R9545
Type:initiation region
Name:Dcaf8_1
Description:DDB1 and CUL4 associated factor 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01390,532,294 - 90,532,354EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308513 AgrOrtholog
BioCyc Gene G2FUF-17330 BioCyc
Ensembl Genes ENSRNOG00000006785 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000008944 ENTREZGENE
  ENSRNOT00000082469 ENTREZGENE
  ENSRNOT00000101398 ENTREZGENE
  ENSRNOT00000101398.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134976 IMAGE-MGC_LOAD
InterPro DCAF8 UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:364050 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95309 IMAGE-MGC_LOAD
NCBI Gene 364050 ENTREZGENE
PANTHER DDB1- AND CUL4-ASSOCIATED FACTOR 8 UniProtKB/Swiss-Prot
  PTHR15574 UniProtKB/Swiss-Prot
Pfam WD40 UniProtKB/Swiss-Prot
PhenoGen Dcaf8 PhenoGen
PROSITE WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000006785 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A0G2JYN0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZX81_RAT UniProtKB/TrEMBL
  A0A8L2Q3J7 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M5N5_RAT UniProtKB/TrEMBL
  A6JG32 ENTREZGENE, UniProtKB/TrEMBL
  DCAF8_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Dcaf8  DDB1 and CUL4 associated factor 8  Wdr42a  WD repeat domain 42A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Wdr42a  WD repeat domain 42A  RGD1308513  similar to expressed sequence AA408877  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1308513  similar to expressed sequence AA408877  RGD1308513_predicted  similar to expressed sequence AA408877 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1308513_predicted  similar to expressed sequence AA408877 (predicted)  LOC364050_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC364050_predicted  similar to expressed sequence AA408877 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL