Plek (pleckstrin) - Rat Genome Database

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Gene: Plek (pleckstrin) Rattus norvegicus
Analyze
Symbol: Plek
Name: pleckstrin
RGD ID: 1308269
Description: Predicted to enable several functions, including phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; exocytosis; and positive regulation of cellular component organization. Predicted to be located in cytoplasm and ruffle membrane. Predicted to be active in plasma membrane. Orthologous to human PLEK (pleckstrin); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC364206; MGC112902
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81495,598,650 - 95,631,326 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1495,598,654 - 95,655,721 (-)EnsemblGRCr8
mRatBN7.21491,397,015 - 91,429,693 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1491,397,019 - 91,454,131 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1495,711,348 - 95,744,200 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01496,955,673 - 96,988,529 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01493,420,742 - 93,453,592 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1496,097,519 - 96,130,172 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1494,721,802 - 94,754,652 (-)NCBILyon_Normotensive
Lyon_Hypertensive1496,248,775 - 96,281,432 (-)NCBILyon_Hypertensive
F344_StmMcwi1495,141,350 - 95,174,071 (-)NCBIF344_StmMcwi
Rnor_6.014100,151,518 - 100,184,192 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14100,151,210 - 100,217,913 (-)Ensemblrn6Rnor6.0
Rnor_5.014100,353,685 - 100,386,531 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41497,841,595 - 97,875,052 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1490,445,003 - 90,477,678 (-)NCBICelera
RGSC_v3.11497,860,739 - 97,894,197 (-)NCBI
Cytogenetic Map14q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
dextran sulfate  (ISO)
diethyl maleate  (EXP)
dimethylarsinic acid  (ISO)
dioleoyl phosphatidic acid  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
glyphosate  (EXP)
guanosine 5'-[gamma-thio]triphosphate  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
methylarsonic acid  (ISO)
Moniliformin  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitrates  (ISO)
Nutlin-3  (ISO)
oleic acid  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidylethanol  (ISO)
pioglitazone  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
vincristine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
plasma membrane  (IBA)
ruffle membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2768345   PMID:7559487   PMID:7782310   PMID:8615792   PMID:8694752   PMID:8999861   PMID:9060471   PMID:10497244   PMID:10995449   PMID:12477932   PMID:15489334   PMID:15698571  
PMID:19190246   PMID:19946888   PMID:23382103  


Genomics

Comparative Map Data
Plek
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81495,598,650 - 95,631,326 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1495,598,654 - 95,655,721 (-)EnsemblGRCr8
mRatBN7.21491,397,015 - 91,429,693 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1491,397,019 - 91,454,131 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1495,711,348 - 95,744,200 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01496,955,673 - 96,988,529 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01493,420,742 - 93,453,592 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1496,097,519 - 96,130,172 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1494,721,802 - 94,754,652 (-)NCBILyon_Normotensive
Lyon_Hypertensive1496,248,775 - 96,281,432 (-)NCBILyon_Hypertensive
F344_StmMcwi1495,141,350 - 95,174,071 (-)NCBIF344_StmMcwi
Rnor_6.014100,151,518 - 100,184,192 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14100,151,210 - 100,217,913 (-)Ensemblrn6Rnor6.0
Rnor_5.014100,353,685 - 100,386,531 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41497,841,595 - 97,875,052 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1490,445,003 - 90,477,678 (-)NCBICelera
RGSC_v3.11497,860,739 - 97,894,197 (-)NCBI
Cytogenetic Map14q22NCBI
PLEK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38268,365,282 - 68,397,453 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl268,365,282 - 68,397,453 (+)Ensemblhg38GRCh38
GRCh37268,592,414 - 68,624,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36268,445,826 - 68,478,089 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34268,504,074 - 68,536,233NCBI
Celera268,441,906 - 68,474,166 (+)NCBICelera
Cytogenetic Map2p14NCBI
HuRef268,329,667 - 68,361,928 (+)NCBIHuRef
CHM1_1268,523,094 - 68,555,363 (+)NCBICHM1_1
T2T-CHM13v2.0268,375,241 - 68,408,023 (+)NCBIT2T-CHM13v2.0
Plek
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391116,921,206 - 16,958,718 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1116,921,206 - 17,002,381 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381116,971,206 - 17,008,718 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1116,971,206 - 17,052,381 (-)Ensemblmm10GRCm38
MGSCv371116,871,209 - 16,908,721 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361116,871,451 - 16,908,705 (-)NCBIMGSCv36mm8
Celera1117,344,383 - 17,382,015 (-)NCBICelera
Cytogenetic Map11A2NCBI
cM Map119.41NCBI
Plek
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542416,493,960 - 16,524,998 (-)Ensembl
ChiLan1.0NW_00495542416,494,052 - 16,524,790 (-)NCBIChiLan1.0ChiLan1.0
PLEK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21258,010,086 - 58,042,467 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A58,014,034 - 58,046,403 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A68,414,281 - 68,446,647 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A69,537,983 - 69,570,393 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A69,537,983 - 69,570,393 (+)EnsemblpanPan2panpan1.1
PLEK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11067,395,972 - 67,421,247 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1067,395,972 - 67,421,247 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1067,285,901 - 67,311,154 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01068,415,503 - 68,440,783 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1068,415,508 - 68,440,783 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11068,098,493 - 68,123,539 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01068,396,757 - 68,422,024 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01068,691,992 - 68,717,126 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Plek
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629215,753,019 - 15,814,303 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649112,762,328 - 12,818,306 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649112,762,421 - 12,818,249 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl373,877,743 - 73,906,667 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1373,877,741 - 73,910,163 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2377,408,772 - 77,437,488 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11438,689,387 - 38,769,090 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1438,689,393 - 38,745,893 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604573,220,871 - 73,287,225 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plek
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247624,939,599 - 4,967,371 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247624,939,683 - 4,967,327 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Plek
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11185,483,814 - 85,510,205 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Plek
371 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:35
Interacting mature miRNAs:42
Transcripts:ENSRNOT00000007044
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)1486271332100078267Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat

Markers in Region
AI556803  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21491,397,123 - 91,397,217 (+)MAPPERmRatBN7.2
Rnor_6.014100,151,627 - 100,151,720NCBIRnor6.0
Rnor_5.014100,386,329 - 100,386,422UniSTSRnor5.0
RGSC_v3.41497,841,704 - 97,841,797UniSTSRGSC3.4
Celera1490,445,112 - 90,445,205UniSTS
RH 3.4 Map14675.1UniSTS
Cytogenetic Map14q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000007044   ⟹   ENSRNOP00000007044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1495,598,654 - 95,631,326 (-)Ensembl
mRatBN7.2 Ensembl1491,397,019 - 91,429,693 (-)Ensembl
Rnor_6.0 Ensembl14100,151,509 - 100,184,192 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079167   ⟹   ENSRNOP00000072547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1495,598,654 - 95,649,601 (-)Ensembl
mRatBN7.2 Ensembl1491,397,019 - 91,454,131 (-)Ensembl
Rnor_6.0 Ensembl14100,151,210 - 100,217,913 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094345   ⟹   ENSRNOP00000083092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1495,604,554 - 95,655,721 (-)Ensembl
mRatBN7.2 Ensembl1491,402,529 - 91,429,693 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095990   ⟹   ENSRNOP00000095833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1491,404,926 - 91,429,693 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110240   ⟹   ENSRNOP00000094759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1495,604,554 - 95,617,843 (-)Ensembl
mRatBN7.2 Ensembl1491,402,529 - 91,416,208 (-)Ensembl
RefSeq Acc Id: NM_001025750   ⟹   NP_001020921
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81495,598,650 - 95,631,326 (-)NCBI
mRatBN7.21491,397,015 - 91,429,693 (-)NCBI
Dahl_SR_JrHsd1496,097,519 - 96,130,172 (-)NCBI
Lyon_Normotensive1494,721,802 - 94,754,652 (-)NCBI
Lyon_Hypertensive1496,248,775 - 96,281,432 (-)NCBI
F344_StmMcwi1495,141,350 - 95,174,071 (-)NCBI
Rnor_6.014100,151,518 - 100,184,192 (-)NCBI
Rnor_5.014100,353,685 - 100,386,531 (+)NCBI
RGSC_v3.41497,841,595 - 97,875,052 (-)RGD
Celera1490,445,003 - 90,477,678 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251520   ⟹   XP_006251582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81495,604,554 - 95,631,320 (-)NCBI
mRatBN7.21491,402,919 - 91,429,687 (-)NCBI
Rnor_6.014100,157,422 - 100,184,186 (-)NCBI
Rnor_5.014100,353,685 - 100,386,531 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001020921 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251582 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98846 (Get FASTA)   NCBI Sequence Viewer  
  EDL97900 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007044
  ENSRNOP00000007044.3
  ENSRNOP00000083092
  ENSRNOP00000083092.1
GenBank Protein Q4KM33 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020921   ⟸   NM_001025750
- UniProtKB: Q4KM33 (UniProtKB/Swiss-Prot),   A6JPY3 (UniProtKB/TrEMBL),   A0A8I6ANN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251582   ⟸   XM_006251520
- Peptide Label: isoform X1
- UniProtKB: Q4KM33 (UniProtKB/Swiss-Prot),   A6JPY3 (UniProtKB/TrEMBL),   A0A8I6ANN0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072547   ⟸   ENSRNOT00000079167
Ensembl Acc Id: ENSRNOP00000007044   ⟸   ENSRNOT00000007044
Ensembl Acc Id: ENSRNOP00000094759   ⟸   ENSRNOT00000110240
Ensembl Acc Id: ENSRNOP00000095833   ⟸   ENSRNOT00000095990
Ensembl Acc Id: ENSRNOP00000083092   ⟸   ENSRNOT00000094345
Protein Domains
DEP   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KM33-F1-model_v2 AlphaFold Q4KM33 1-350 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699501
Promoter ID:EPDNEW_R10023
Type:single initiation site
Name:Plek_1
Description:pleckstrin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014100,184,047 - 100,184,107EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308269 AgrOrtholog
BioCyc Gene G2FUF-14939 BioCyc
Ensembl Genes ENSRNOG00000005214 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007044 ENTREZGENE
  ENSRNOT00000007044.6 UniProtKB/Swiss-Prot
  ENSRNOT00000094345 ENTREZGENE
  ENSRNOT00000094345.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7379453 IMAGE-MGC_LOAD
InterPro DEP_dom UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
  Pleckstrin UniProtKB/Swiss-Prot
  PLEK1_DEP UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  WH_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report rno:364206 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112902 IMAGE-MGC_LOAD
NCBI Gene 364206 ENTREZGENE
PANTHER PLECKSTRIN UniProtKB/Swiss-Prot
  PLECKSTRIN UniProtKB/Swiss-Prot
Pfam DEP UniProtKB/Swiss-Prot
  PF00169 UniProtKB/Swiss-Prot
PhenoGen Plek PhenoGen
PROSITE DEP UniProtKB/Swiss-Prot
  PH_DOMAIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005214 RatGTEx
SMART DEP UniProtKB/Swiss-Prot
  SM00233 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF46785 UniProtKB/Swiss-Prot
UniProt A0A0G2K393_RAT UniProtKB/TrEMBL
  A0A8I6ANN0 ENTREZGENE, UniProtKB/TrEMBL
  A6JPY3 ENTREZGENE, UniProtKB/TrEMBL
  PLEK_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Plek  pleckstrin  Plek_predicted  pleckstrin (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Plek_predicted  pleckstrin (predicted)      Symbol and Name status set to approved 70820 APPROVED