Usp44 (ubiquitin specific peptidase 44) - Rat Genome Database

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Gene: Usp44 (ubiquitin specific peptidase 44) Rattus norvegicus
Analyze
Symbol: Usp44
Name: ubiquitin specific peptidase 44
RGD ID: 1308216
Description: Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including proteasome-mediated ubiquitin-dependent protein catabolic process; protein deubiquitination; and regulation of mitotic metaphase/anaphase transition. Predicted to act upstream of or within antiviral innate immune response; positive regulation of mitotic metaphase/anaphase transition; and regulatory T cell differentiation. Predicted to be active in cytoplasm and nucleus. Orthologous to human USP44 (ubiquitin specific peptidase 44); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC314746; ubiquitin carboxyl-terminal hydrolase 44; ubiquitin specific protease 44; ubiquitin thiolesterase 44
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8730,251,142 - 30,301,185 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl730,251,205 - 30,297,906 (+)EnsemblGRCr8
mRatBN7.2728,364,169 - 28,412,039 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl728,364,033 - 28,410,053 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx730,354,579 - 30,400,607 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0732,516,806 - 32,562,843 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0732,294,256 - 32,340,284 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0734,714,293 - 34,759,352 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl734,744,483 - 34,759,206 (+)Ensemblrn6Rnor6.0
Rnor_5.0734,773,627 - 34,818,325 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4730,898,472 - 30,971,342 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera725,461,222 - 25,507,052 (+)NCBICelera
RGSC_v3.1730,965,952 - 30,991,469 (+)NCBI
Cytogenetic Map7q13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
fibrillar center  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. H2A-DUBbing the mammalian epigenome: expanding frontiers for histone H2A deubiquitinating enzymes in cell biology and physiology. Belle JI and Nijnik A, Int J Biochem Cell Biol. 2014 May;50:161-74. doi: 10.1016/j.biocel.2014.03.004. Epub 2014 Mar 16.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Push back to respond better: regulatory inhibition of the DNA double-strand break response. Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:14715245   PMID:17443180   PMID:20402667   PMID:21853124   PMID:23187126  


Genomics

Comparative Map Data
Usp44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8730,251,142 - 30,301,185 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl730,251,205 - 30,297,906 (+)EnsemblGRCr8
mRatBN7.2728,364,169 - 28,412,039 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl728,364,033 - 28,410,053 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx730,354,579 - 30,400,607 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0732,516,806 - 32,562,843 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0732,294,256 - 32,340,284 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0734,714,293 - 34,759,352 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl734,744,483 - 34,759,206 (+)Ensemblrn6Rnor6.0
Rnor_5.0734,773,627 - 34,818,325 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4730,898,472 - 30,971,342 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera725,461,222 - 25,507,052 (+)NCBICelera
RGSC_v3.1730,965,952 - 30,991,469 (+)NCBI
Cytogenetic Map7q13NCBI
USP44
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381295,516,560 - 95,551,681 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1295,516,560 - 95,553,341 (-)Ensemblhg38GRCh38
GRCh371295,910,336 - 95,945,252 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361294,435,010 - 94,469,394 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341294,414,016 - 94,447,695NCBI
Celera1295,582,001 - 95,617,069 (-)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1292,978,712 - 93,013,655 (-)NCBIHuRef
CHM1_11295,875,781 - 95,910,674 (-)NCBICHM1_1
T2T-CHM13v2.01295,497,607 - 95,532,730 (-)NCBIT2T-CHM13v2.0
Usp44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391093,655,831 - 93,696,792 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1093,667,417 - 93,693,950 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381093,819,969 - 93,859,425 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1093,831,555 - 93,858,088 (+)Ensemblmm10GRCm38
MGSCv371093,294,300 - 93,311,283 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361093,261,354 - 93,278,337 (+)NCBIMGSCv36mm8
Celera1095,801,275 - 95,819,046 (+)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1048.67NCBI
Usp44
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540531,977,602 - 32,006,810 (-)Ensembl
ChiLan1.0NW_00495540531,977,045 - 32,006,733 (-)NCBIChiLan1.0ChiLan1.0
USP44
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210103,592,727 - 103,628,336 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112103,589,117 - 103,624,726 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01293,111,293 - 93,146,889 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11296,503,794 - 96,539,321 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1296,503,794 - 96,536,094 (-)EnsemblpanPan2panpan1.1
USP44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11535,401,486 - 35,454,351 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1535,402,207 - 35,414,261 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1535,788,165 - 35,841,019 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01536,066,187 - 36,119,066 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1536,066,193 - 36,093,614 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11535,339,057 - 35,391,905 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01535,433,598 - 35,486,456 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01535,696,753 - 35,749,591 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Usp44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494524,527,677 - 24,572,367 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650711,660,129 - 11,681,366 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493650711,663,069 - 11,692,174 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl587,875,851 - 87,889,680 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1587,864,410 - 87,890,913 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2592,044,399 - 92,091,188 (+)NCBISscrofa10.2Sscrofa10.2susScr3
USP44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11190,915,107 - 90,950,142 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1190,916,677 - 90,947,456 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037154,220,917 - 154,254,742 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp44
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475011,710,218 - 11,724,529 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475011,697,919 - 11,725,421 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Usp44
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11172,926,528 - 172,940,524 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Usp44
320 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:566
Count of miRNA genes:246
Interacting mature miRNAs:294
Transcripts:ENSRNOT00000007465
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)72154197751639954Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)72154197751639954Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)72154197735707405Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72092049437412865Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
RH139951  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2728,363,620 - 28,363,815 (+)MAPPERmRatBN7.2
Rnor_6.0734,713,719 - 34,713,913NCBIRnor6.0
Rnor_5.0734,773,053 - 34,773,247UniSTSRnor5.0
RGSC_v3.4730,897,898 - 30,898,092UniSTSRGSC3.4
Celera725,460,648 - 25,460,842UniSTS
RH 3.4 Map7193.2UniSTS
Cytogenetic Map7q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 10 52 142 63 62 31 92 31 6 298 176 11 121 69 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000007465   ⟹   ENSRNOP00000007465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl730,251,205 - 30,296,961 (+)Ensembl
mRatBN7.2 Ensembl728,364,033 - 28,410,053 (+)Ensembl
Rnor_6.0 Ensembl734,744,483 - 34,759,206 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105243   ⟹   ENSRNOP00000089591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl730,251,205 - 30,296,962 (+)Ensembl
mRatBN7.2 Ensembl728,364,033 - 28,410,053 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000124420   ⟹   ENSRNOP00000107316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl730,269,247 - 30,297,906 (+)Ensembl
RefSeq Acc Id: NM_001394071   ⟹   NP_001381000
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,205 - 30,297,235 (+)NCBI
mRatBN7.2728,364,196 - 28,410,231 (+)NCBI
RefSeq Acc Id: NR_172074
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,205 - 30,297,235 (+)NCBI
mRatBN7.2728,364,196 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079054   ⟹   XP_038934982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,142 - 30,296,963 (+)NCBI
mRatBN7.2728,364,184 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079055   ⟹   XP_038934983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,171 - 30,296,963 (+)NCBI
mRatBN7.2728,364,169 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079060   ⟹   XP_038934988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,271,336 - 30,296,963 (+)NCBI
mRatBN7.2728,384,364 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079061   ⟹   XP_038934989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,156 - 30,296,963 (+)NCBI
mRatBN7.2728,364,200 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079063   ⟹   XP_038934991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,171 - 30,296,963 (+)NCBI
mRatBN7.2728,364,169 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079068   ⟹   XP_038934996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,271,379 - 30,296,963 (+)NCBI
mRatBN7.2728,384,369 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_063263444   ⟹   XP_063119514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,170 - 30,301,185 (+)NCBI
RefSeq Acc Id: XM_063263445   ⟹   XP_063119515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,168 - 30,295,729 (+)NCBI
Ensembl Acc Id: ENSRNOP00000007465   ⟸   ENSRNOT00000007465
RefSeq Acc Id: XP_038934991   ⟸   XM_039079063
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A942 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934983   ⟸   XM_039079055
- Peptide Label: isoform X1
- UniProtKB: D4A251 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934982   ⟸   XM_039079054
- Peptide Label: isoform X1
- UniProtKB: D4A251 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934989   ⟸   XM_039079061
- Peptide Label: isoform X1
- UniProtKB: D4A251 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934988   ⟸   XM_039079060
- Peptide Label: isoform X1
- UniProtKB: D4A251 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934996   ⟸   XM_039079068
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A942 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000089591   ⟸   ENSRNOT00000105243
RefSeq Acc Id: NP_001381000   ⟸   NM_001394071
- UniProtKB: A0A8I6A942 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119515   ⟸   XM_063263445
- Peptide Label: isoform X3
- UniProtKB: A6IFZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119514   ⟸   XM_063263444
- Peptide Label: isoform X1
- UniProtKB: D4A251 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000107316   ⟸   ENSRNOT00000124420
Protein Domains
UBP-type   USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A251-F1-model_v2 AlphaFold D4A251 1-714 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308216 AgrOrtholog
BioCyc Gene G2FUF-34382 BioCyc
Ensembl Genes ENSRNOG00000005637 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007465 ENTREZGENE
  ENSRNOT00000007465.7 UniProtKB/TrEMBL
  ENSRNOT00000105243 ENTREZGENE
  ENSRNOT00000105243.2 UniProtKB/TrEMBL
  ENSRNOT00000124420 ENTREZGENE
  ENSRNOT00000124420.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  Ub_carboxyl-term_hydrolase UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
NCBI Gene 314746 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 44 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
PhenoGen Usp44 PhenoGen
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005637 RatGTEx
SMART ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A8I6A942 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LXY4_RAT UniProtKB/TrEMBL
  A6IFZ4 ENTREZGENE, UniProtKB/TrEMBL
  D4A251 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-07 Usp44  ubiquitin specific peptidase 44  Usp44  ubiquitin specific protease 44  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Usp44  ubiquitin specific protease 44   Usp44_predicted  ubiquitin specific protease 44 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Usp44_predicted  ubiquitin specific protease 44 (predicted)      Symbol and Name status set to approved 70820 APPROVED