Prorsd1 (prolyl-tRNA synthetase associated domain containing 1) - Rat Genome Database

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Gene: Prorsd1 (prolyl-tRNA synthetase associated domain containing 1) Rattus norvegicus
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Symbol: Prorsd1
Name: prolyl-tRNA synthetase associated domain containing 1
RGD ID: 1308179
Description: Predicted to enable aminoacyl-tRNA deacylase activity. Predicted to be involved in aminoacyl-tRNA metabolism involved in translational fidelity. Orthologous to human PRORSD1P (prolyl-tRNA synthetase associated domain containing 1, pseudogene); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; caffeine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC289864; Ncrna00117; PrdX-deacylase domain 1; prdX-deacylase domain-containing protein 1; prolyl-tRNA synthetase associated domain containing 1, pseudogene; Prorsd1p; RGD1308179; similar to RIKEN cDNA 2010316F05
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814107,458,910 - 107,461,179 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl14107,458,857 - 107,461,205 (-)EnsemblGRCr8
mRatBN7.214103,257,979 - 103,260,248 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14103,257,979 - 103,260,248 (-)EnsemblmRatBN7.2
UTH_Rnor_SHRSP_BbbUtx_1.014108,831,567 - 108,833,822 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014105,304,000 - 105,306,255 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd14107,964,845 - 107,967,100 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive14106,601,470 - 106,603,737 (-)NCBILyon_Normotensive
Lyon_Hypertensive14108,147,582 - 108,149,849 (-)NCBILyon_Hypertensive
F344_StmMcwi14106,970,066 - 106,972,327 (-)NCBIF344_StmMcwi
Rnor_6.014113,938,061 - 113,940,330 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,938,061 - 113,940,330 (-)Ensemblrn6Rnor6.0
Rnor_5.014113,604,440 - 113,606,709 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414110,530,889 - 110,533,157 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera14102,135,084 - 102,137,353 (-)NCBICelera
RGSC_v3.114110,557,244 - 110,559,466 (-)NCBI
Cytogenetic Map14q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Prorsd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814107,458,910 - 107,461,179 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl14107,458,857 - 107,461,205 (-)EnsemblGRCr8
mRatBN7.214103,257,979 - 103,260,248 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14103,257,979 - 103,260,248 (-)EnsemblmRatBN7.2
UTH_Rnor_SHRSP_BbbUtx_1.014108,831,567 - 108,833,822 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014105,304,000 - 105,306,255 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd14107,964,845 - 107,967,100 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive14106,601,470 - 106,603,737 (-)NCBILyon_Normotensive
Lyon_Hypertensive14108,147,582 - 108,149,849 (-)NCBILyon_Hypertensive
F344_StmMcwi14106,970,066 - 106,972,327 (-)NCBIF344_StmMcwi
Rnor_6.014113,938,061 - 113,940,330 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,938,061 - 113,940,330 (-)Ensemblrn6Rnor6.0
Rnor_5.014113,604,440 - 113,606,709 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414110,530,889 - 110,533,157 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera14102,135,084 - 102,137,353 (-)NCBICelera
RGSC_v3.114110,557,244 - 110,559,466 (-)NCBI
Cytogenetic Map14q22NCBI
PRORSD1P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38255,282,319 - 55,284,472 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl255,282,329 - 55,284,437 (+)Ensemblhg38GRCh38
GRCh38.p14 Ensembl255,279,535 - 55,346,049 (+)Ensemblhg38GRCh38
GRCh37255,509,455 - 55,511,608 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36255,362,982 - 55,365,112 (+)NCBIBuild 36Build 36hg18NCBI36
Celera255,349,956 - 55,352,107 (+)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef255,244,514 - 55,246,665 (+)NCBIHuRef
CHM1_1255,439,465 - 55,441,616 (+)NCBICHM1_1
T2T-CHM13v2.0255,279,543 - 55,281,678 (+)NCBIT2T-CHM13v2.0
Prorsd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391129,461,757 - 29,465,033 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1129,461,757 - 29,465,033 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381129,511,757 - 29,515,033 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1129,511,757 - 29,515,033 (-)Ensemblmm10GRCm38
MGSCv371129,411,757 - 29,415,033 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361129,413,055 - 29,415,033 (-)NCBIMGSCv36mm8
Celera1131,873,071 - 31,876,339 (-)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1116.75NCBI
LOC100856725
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11056,164,372 - 56,165,883 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1056,120,464 - 56,122,478 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01057,168,326 - 57,169,840 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11056,869,440 - 56,870,954 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01057,148,673 - 57,150,187 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01057,439,210 - 57,440,715 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC100514282
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1385,945,344 - 85,947,578 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2390,729,092 - 90,731,552 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:36
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000005504
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat

Markers in Region
AW533996  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.214103,258,046 - 103,258,203 (+)MAPPERmRatBN7.2
Rnor_6.014113,938,129 - 113,938,285NCBIRnor6.0
Rnor_5.014113,604,508 - 113,604,664UniSTSRnor5.0
RGSC_v3.414110,530,957 - 110,531,113UniSTSRGSC3.4
Celera14102,135,152 - 102,135,308UniSTS
Cytogenetic Map14q22UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 16 12 150 249 91 90 65 138 59 22 484 330 11 228 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005504   ⟹   ENSRNOP00000005504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl14107,458,857 - 107,461,205 (-)Ensembl
mRatBN7.2 Ensembl14103,257,979 - 103,260,248 (-)Ensembl
Rnor_6.0 Ensembl14113,938,061 - 113,940,330 (-)Ensembl
RefSeq Acc Id: NM_001106022   ⟹   NP_001099492
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814107,458,910 - 107,461,179 (-)NCBI
mRatBN7.214103,257,979 - 103,260,248 (-)NCBI
Dahl_SR_JrHsd14107,964,845 - 107,967,100 (-)NCBI
Lyon_Normotensive14106,601,470 - 106,603,737 (-)NCBI
Lyon_Hypertensive14108,147,582 - 108,149,849 (-)NCBI
F344_StmMcwi14106,970,066 - 106,972,327 (-)NCBI
Rnor_6.014113,938,061 - 113,940,330 (-)NCBI
Rnor_5.014113,604,440 - 113,606,709 (-)NCBI
RGSC_v3.414110,530,889 - 110,533,157 (-)RGD
Celera14102,135,084 - 102,137,353 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099492 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI67083 (Get FASTA)   NCBI Sequence Viewer  
  EDL98031 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005504
  ENSRNOP00000005504.5
RefSeq Acc Id: NP_001099492   ⟸   NM_001106022
- UniProtKB: B2RZA5 (UniProtKB/TrEMBL),   A6JQB4 (UniProtKB/TrEMBL),   F7EP18 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005504   ⟸   ENSRNOT00000005504
Protein Domains
YbaK/aminoacyl-tRNA synthetase-associated

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RZA5-F1-model_v2 AlphaFold B2RZA5 1-169 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699533
Promoter ID:EPDNEW_R10057
Type:single initiation site
Name:Prorsd1_1
Description:prolyl-tRNA synthetase associated domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014113,940,309 - 113,940,369EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308179 AgrOrtholog
BioCyc Gene G2FUF-14651 BioCyc
Ensembl Genes ENSRNOG00000004145 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005504 ENTREZGENE
  ENSRNOT00000005504.9 UniProtKB/TrEMBL
Gene3D-CATH 3.90.960.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5620957 IMAGE-MGC_LOAD
InterPro ProX/PRXD1 UniProtKB/TrEMBL
  YbaK/aa-tRNA-synt-asso_dom_sf UniProtKB/TrEMBL
  YbaK/aa-tRNA-synth-assoc-dom UniProtKB/TrEMBL
KEGG Report rno:289864 UniProtKB/TrEMBL
MGC_CLONE MGC:189459 IMAGE-MGC_LOAD
NCBI Gene 289864 ENTREZGENE
PANTHER PROLYL-TRNA SYNTHETASE ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED UniProtKB/TrEMBL
  PTHR31423 UniProtKB/TrEMBL
Pfam YbaK UniProtKB/TrEMBL
PhenoGen Prorsd1 PhenoGen
RatGTEx ENSRNOG00000004145 RatGTEx
Superfamily-SCOP YbaK/aa-tRNA-synth-assoc-reg UniProtKB/TrEMBL
UniProt A0ABZ3NNM8_RAT UniProtKB/TrEMBL
  A6JQB4 ENTREZGENE, UniProtKB/TrEMBL
  B2RZA5 ENTREZGENE
  F7EP18 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B2RZA5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-18 Prorsd1  prolyl-tRNA synthetase associated domain containing 1  Prorsd1  prolyl-tRNA synthetase associated domain containing 1, pseudogene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-16 Prorsd1  prolyl-tRNA synthetase associated domain containing 1, pseudogene  Prorsd1p  prolyl-tRNA synthetase associated domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-02 Prorsd1p  prolyl-tRNA synthetase associated domain containing 1  Ncrna00117  non-protein coding RNA 117  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-12 Ncrna00117  non-protein coding RNA 117  RGD1308179  similar to RIKEN cDNA 2010316F05   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1308179  similar to RIKEN cDNA 2010316F05   RGD1308179_predicted  similar to RIKEN cDNA 2010316F05 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308179_predicted  similar to RIKEN cDNA 2010316F05 (predicted)  LOC289864_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC289864_predicted  similar to RIKEN cDNA 2010316F05 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL