Plac8 (placenta associated 8) - Rat Genome Database

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Gene: Plac8 (placenta associated 8) Rattus norvegicus
Analyze
Symbol: Plac8
Name: placenta associated 8
RGD ID: 1308102
Description: Predicted to enable chromatin binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including brown fat cell differentiation; defense response to bacterium; and response to cold. Biomarker of glucose intolerance. Orthologous to human PLAC8 (placenta associated 8); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100910270; LOC360914; placenta-specific 8; placenta-specific gene 8 protein; uncharacterized LOC100910270
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Niddm20
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,356,950 - 9,378,586 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl149,356,972 - 9,378,572 (+)EnsemblGRCr8
mRatBN7.2149,052,601 - 9,074,264 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl149,063,048 - 9,074,264 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx149,024,175 - 9,045,882 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01410,324,037 - 10,345,742 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0149,020,655 - 9,042,362 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01410,692,799 - 10,714,556 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1410,692,764 - 10,714,524 (+)Ensemblrn6Rnor6.0
Rnor_5.01410,640,286 - 10,661,811 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41410,302,667 - 10,325,559 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera149,161,291 - 9,183,206 (+)NCBICelera
RGSC_v3.11410,273,445 - 10,325,545 (+)NCBI
Cytogenetic Map14p22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acetamiprid  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (ISO)
choline  (ISO)
chrysene  (ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dichlorine  (ISO)
diclofenac  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hexadecanoic acid  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lead nitrate  (ISO)
leflunomide  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (EXP,ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methotrexate  (ISO)
methylmercury chloride  (EXP)
methylparaben  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
okadaic acid  (ISO)
olanzapine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorononanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
quinolin-8-ol  (ISO)
rimonabant  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
Sunset Yellow FCF  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
triticonazole  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Plac8 is an inducer of C/EBPß required for brown fat differentiation, thermoregulation, and control of body weight. Jimenez-Preitner M, etal., Cell Metab. 2011 Nov 2;14(5):658-70. doi: 10.1016/j.cmet.2011.08.008. Epub 2011 Oct 6.
3. Plac8-dependent and inducible NO synthase-dependent mechanisms clear Chlamydia muridarum infections from the genital tract. Johnson RM, etal., J Immunol. 2012 Feb 15;188(4):1896-904. doi: 10.4049/jimmunol.1102764. Epub 2012 Jan 11.
4. Impaired host defense in mice lacking ONZIN. Ledford JG, etal., J Immunol. 2007 Apr 15;178(8):5132-43. doi: 10.4049/jimmunol.178.8.5132.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats. Sasaki D, etal., Mamm Genome. 2015 Dec;26(11-12):619-29. doi: 10.1007/s00335-015-9597-4. Epub 2015 Aug 22.
7. Placenta-specific 8 limits IFNγ production by CD4 T cells in vitro and promotes establishment of influenza-specific CD8 T cells in vivo. Slade CD, etal., PLoS One. 2020 Jul 8;15(7):e0235706. doi: 10.1371/journal.pone.0235706. eCollection 2020.
Additional References at PubMed
PMID:12407160   PMID:12477932   PMID:16611984  


Genomics

Comparative Map Data
Plac8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,356,950 - 9,378,586 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl149,356,972 - 9,378,572 (+)EnsemblGRCr8
mRatBN7.2149,052,601 - 9,074,264 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl149,063,048 - 9,074,264 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx149,024,175 - 9,045,882 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01410,324,037 - 10,345,742 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0149,020,655 - 9,042,362 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01410,692,799 - 10,714,556 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1410,692,764 - 10,714,524 (+)Ensemblrn6Rnor6.0
Rnor_5.01410,640,286 - 10,661,811 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41410,302,667 - 10,325,559 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera149,161,291 - 9,183,206 (+)NCBICelera
RGSC_v3.11410,273,445 - 10,325,545 (+)NCBI
Cytogenetic Map14p22NCBI
PLAC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38483,090,048 - 83,114,729 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl483,059,493 - 83,137,075 (-)Ensemblhg38GRCh38
GRCh37484,011,201 - 84,035,882 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36484,230,867 - 84,254,913 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34484,369,019 - 84,393,068NCBI
Celera481,301,714 - 81,326,359 (-)NCBICelera
Cytogenetic Map4q21.22NCBI
HuRef479,752,244 - 79,779,026 (-)NCBIHuRef
CHM1_1483,987,686 - 84,012,382 (-)NCBICHM1_1
T2T-CHM13v2.0486,419,237 - 86,443,896 (-)NCBIT2T-CHM13v2.0
Plac8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395100,699,455 - 100,720,119 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5100,701,591 - 100,720,111 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm385100,551,589 - 100,572,253 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5100,553,725 - 100,572,245 (-)Ensemblmm10GRCm38
MGSCv375100,982,752 - 101,001,224 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365100,794,035 - 100,812,507 (-)NCBIMGSCv36mm8
Celera597,879,678 - 97,898,791 (-)NCBICelera
Cytogenetic Map5E4NCBI
cM Map548.49NCBI
Plac8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554746,522,204 - 6,534,312 (+)Ensembl
ChiLan1.0NW_0049554746,518,459 - 6,533,251 (+)NCBIChiLan1.0ChiLan1.0
PLAC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2346,957,286 - 46,982,509 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1447,146,634 - 47,171,812 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0441,089,847 - 41,115,061 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1446,939,019 - 46,964,131 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl446,943,940 - 46,964,131 (+)EnsemblpanPan2panpan1.1
PLAC8B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1327,004,147 - 7,049,877 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl327,007,753 - 7,029,140 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3234,835,491 - 34,881,280 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0327,025,506 - 7,071,390 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl327,029,110 - 7,050,585 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1327,096,360 - 7,142,074 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0326,964,929 - 7,010,717 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03232,951,037 - 32,996,662 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Plac8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052855,323,061 - 5,341,351 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367381,484,859 - 1,503,302 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367381,484,905 - 1,503,181 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLAC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.18135,250,761 - 135,279,091 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28144,545,594 - 144,573,932 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLAC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1731,471,166 - 31,496,053 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl731,470,774 - 31,489,432 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603710,049,527 - 10,074,422 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plac8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624900133,889 - 158,050 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624900134,075 - 157,982 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Plac8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11110,775,316 - 10,796,634 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Plac8
211 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:134
Count of miRNA genes:107
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000003012
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14395787818558812Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14111334906Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14117877928Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
724541Niddm53Non-insulin dependent diabetes mellitus QTL 530.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1439578789393298Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat

Markers in Region
UniSTS:463464  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2149,069,552 - 9,069,613 (+)MAPPERmRatBN7.2
Rnor_6.01410,709,868 - 10,709,928NCBIRnor6.0
Rnor_6.0147,509,477 - 7,509,537NCBIRnor6.0
Rnor_5.01410,657,123 - 10,657,183UniSTSRnor5.0
Rnor_5.0147,487,276 - 7,487,336UniSTSRnor5.0
RGSC_v3.41410,320,871 - 10,320,931UniSTSRGSC3.4
Celera149,178,518 - 9,178,578UniSTS
Cytogenetic Map14p22UniSTS
AI230820  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8149,375,746 - 9,375,925 (+)Marker Load Pipeline
mRatBN7.2149,071,411 - 9,071,590 (+)MAPPERmRatBN7.2
Rnor_6.01410,711,717 - 10,711,895NCBIRnor6.0
Rnor_6.0147,511,326 - 7,511,504NCBIRnor6.0
Rnor_5.01410,658,972 - 10,659,150UniSTSRnor5.0
Rnor_5.0147,489,125 - 7,489,303UniSTSRnor5.0
RGSC_v3.41410,322,720 - 10,322,898UniSTSRGSC3.4
Celera149,180,367 - 9,180,545UniSTS
RH 3.4 Map14152.48UniSTS
Cytogenetic Map14p22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 61 127 57 60 41 86 41 298 168 11 117 71 73 19 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000003012   ⟹   ENSRNOP00000003012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,356,972 - 9,378,572 (+)Ensembl
mRatBN7.2 Ensembl149,063,048 - 9,074,264 (+)Ensembl
Rnor_6.0 Ensembl1410,692,764 - 10,714,524 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000157880   ⟹   ENSRNOP00000111947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,358,815 - 9,378,572 (+)Ensembl
RefSeq Acc Id: NM_001108353   ⟹   NP_001101823
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,356,950 - 9,378,586 (+)NCBI
mRatBN7.2149,052,601 - 9,074,264 (+)NCBI
Rnor_6.01410,692,799 - 10,714,556 (+)NCBI
Rnor_5.01410,640,286 - 10,661,811 (+)NCBI
RGSC_v3.41410,302,667 - 10,325,559 (+)RGD
Celera149,161,291 - 9,183,206 (+)RGD
Sequence:
RefSeq Acc Id: XM_063273327   ⟹   XP_063129397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,356,976 - 9,378,579 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101823 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129397 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68910 (Get FASTA)   NCBI Sequence Viewer  
  EDL99562 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003012
  ENSRNOP00000003012.6
  ENSRNOP00000111947.1
RefSeq Acc Id: NP_001101823   ⟸   NM_001108353
- UniProtKB: B5DF36 (UniProtKB/TrEMBL),   F7EWR1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003012   ⟸   ENSRNOT00000003012
RefSeq Acc Id: XP_063129397   ⟸   XM_063273327
- Peptide Label: isoform X1
- UniProtKB: B5DF36 (UniProtKB/TrEMBL),   F7EWR1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111947   ⟸   ENSRNOT00000157880

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DF36-F1-model_v2 AlphaFold B5DF36 1-112 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699194
Promoter ID:EPDNEW_R9718
Type:multiple initiation site
Name:LOC100910270_1
Description:uncharacterized LOC100910270
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01410,692,822 - 10,692,882EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308102 AgrOrtholog
BioCyc Gene G2FUF-16407 BioCyc
Ensembl Genes ENSRNOG00000002217 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003012 ENTREZGENE
  ENSRNOT00000003012.8 UniProtKB/TrEMBL
  ENSRNOT00000157880.1 UniProtKB/TrEMBL
InterPro DUF_Cys-rich UniProtKB/TrEMBL
KEGG Report rno:360914 UniProtKB/TrEMBL
NCBI Gene 360914 ENTREZGENE
PANTHER PTHR15907 UniProtKB/TrEMBL
Pfam PLAC8 UniProtKB/TrEMBL
PhenoGen Plac8 PhenoGen
RatGTEx ENSRNOG00000002217 RatGTEx
UniProt A0ABK0M497_RAT UniProtKB/TrEMBL
  B5DF36 ENTREZGENE, UniProtKB/TrEMBL
  F7EWR1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Plac8  placenta associated 8  LOC100910270  uncharacterized LOC100910270  Data merged from RGD:6499131 737654 PROVISIONAL
2019-04-03 Plac8  placenta associated 8  Plac8  placenta-specific 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100910270  uncharacterized LOC100910270      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Plac8  placenta-specific 8   Plac8_predicted  placenta-specific 8 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Plac8_predicted  placenta-specific 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED