Cnot1 (CCR4-NOT transcription complex, subunit 1) - Rat Genome Database

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Pathways
Gene: Cnot1 (CCR4-NOT transcription complex, subunit 1) Rattus norvegicus
Analyze
Symbol: Cnot1
Name: CCR4-NOT transcription complex, subunit 1
RGD ID: 1308009
Description: Predicted to enable armadillo repeat domain binding activity; molecular adaptor activity; and nuclear receptor binding activity. Predicted to contribute to poly(A)-specific ribonuclease activity. Predicted to be involved in several processes, including negative regulation of intracellular signal transduction; positive regulation of cytoplasmic mRNA processing body assembly; and regulation of gene expression. Predicted to be located in cytosol and nucleus. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. Human ortholog(s) of this gene implicated in Vissers-Bodmer syndrome and holoprosencephaly 12. Orthologous to human CNOT1 (CCR4-NOT transcription complex subunit 1); PARTICIPATES IN microRNA pathway; RNA degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: adrenal gland protein AD-005; CCR4-NOT transcription complex subunit 1; hypothetical protein LOC291841; LOC291841; MGC116302; RGD1308009; similar to KIAA1007 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,261,290 - 9,352,636 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl199,261,294 - 9,352,636 (+)EnsemblGRCr8
mRatBN7.2199,255,190 - 9,346,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,255,194 - 9,346,574 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx199,223,744 - 9,315,039 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0199,990,569 - 10,081,870 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,276,876 - 9,368,186 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0199,668,186 - 9,761,605 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,668,186 - 9,761,605 (+)Ensemblrn6Rnor6.0
Rnor_5.0199,652,472 - 9,746,683 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4199,712,024 - 9,803,182 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera199,151,859 - 9,241,563 (+)NCBICelera
RGSC_v3.1199,788,162 - 9,807,989 (+)NCBI
Cytogenetic Map19p13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
CCR4-NOT complex  (IEA,ISO)
CCR4-NOT core complex  (IBA,IEA)
cytoplasm  (IEA)
nucleus  (IEA)
P-body  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Wahle E and Winkler GS, Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):561-70. doi: 10.1016/j.bbagrm.2013.01.003. Epub 2013 Jan 19.
Additional References at PubMed
PMID:12477932   PMID:16778766   PMID:19558367   PMID:19946888   PMID:20133598   PMID:21278420   PMID:21525035   PMID:21976065   PMID:22367759   PMID:22658674   PMID:22664934   PMID:22681889  
PMID:22977175   PMID:23172285   PMID:23644599   PMID:24736845   PMID:24768540  


Genomics

Comparative Map Data
Cnot1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,261,290 - 9,352,636 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl199,261,294 - 9,352,636 (+)EnsemblGRCr8
mRatBN7.2199,255,190 - 9,346,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,255,194 - 9,346,574 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx199,223,744 - 9,315,039 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0199,990,569 - 10,081,870 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,276,876 - 9,368,186 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0199,668,186 - 9,761,605 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,668,186 - 9,761,605 (+)Ensemblrn6Rnor6.0
Rnor_5.0199,652,472 - 9,746,683 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4199,712,024 - 9,803,182 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera199,151,859 - 9,241,563 (+)NCBICelera
RGSC_v3.1199,788,162 - 9,807,989 (+)NCBI
Cytogenetic Map19p13NCBI
CNOT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381658,519,951 - 58,629,826 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1658,519,951 - 58,629,885 (-)Ensemblhg38GRCh38
GRCh371658,553,855 - 58,663,730 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361657,111,356 - 57,221,251 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1643,052,843 - 43,163,048 (-)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1644,421,846 - 44,532,633 (-)NCBIHuRef
CHM1_11659,961,044 - 60,070,690 (-)NCBICHM1_1
T2T-CHM13v2.01664,315,184 - 64,422,344 (-)NCBIT2T-CHM13v2.0
Cnot1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39896,445,559 - 96,534,741 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl896,446,079 - 96,534,092 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38895,718,931 - 95,808,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl895,719,451 - 95,807,464 (-)Ensemblmm10GRCm38
MGSCv37898,243,351 - 98,331,366 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36898,608,580 - 98,696,595 (-)NCBIMGSCv36mm8
Celera8100,030,369 - 100,118,172 (-)NCBICelera
Cytogenetic Map8D1NCBI
cM Map847.18NCBI
Cnot1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,938,791 - 16,027,545 (-)Ensembl
ChiLan1.0NW_00495543315,938,791 - 16,027,547 (-)NCBIChiLan1.0ChiLan1.0
CNOT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01638,793,212 - 38,902,686 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,919,276 - 58,027,472 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,919,283 - 58,027,472 (-)EnsemblpanPan2panpan1.1
CNOT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,038,456 - 58,138,364 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,038,483 - 58,137,622 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha254,668,858 - 54,768,748 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0258,576,260 - 58,677,212 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl258,576,300 - 58,677,645 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1255,405,764 - 55,506,839 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0256,410,286 - 56,514,088 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0257,308,231 - 57,409,115 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cnot1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934949,204,138 - 49,286,987 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647510,302,087 - 10,384,957 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647510,302,091 - 10,384,945 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNOT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl620,271,596 - 20,372,245 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1620,271,593 - 20,372,300 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2618,405,850 - 18,474,575 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNOT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1544,460,025 - 44,567,843 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl544,455,311 - 44,567,815 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604731,603,098 - 31,711,911 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnot1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474627,676,325 - 27,756,754 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474627,659,424 - 27,757,024 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cnot1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1172,539,392 - 2,624,541 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cnot1
395 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:42
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000016563
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131969901Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124694445Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127361636Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
BF387398  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2199,337,425 - 9,337,576 (+)MAPPERmRatBN7.2
Rnor_6.0199,752,463 - 9,752,613NCBIRnor6.0
Rnor_5.0199,737,541 - 9,737,691UniSTSRnor5.0
RGSC_v3.4199,794,040 - 9,794,190UniSTSRGSC3.4
Celera199,232,690 - 9,232,840UniSTS
RH 3.4 Map1976.92UniSTS
Cytogenetic Map19p13UniSTS
AU047625  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2199,292,337 - 9,292,532 (+)MAPPERmRatBN7.2
Rnor_6.0199,705,315 - 9,705,509NCBIRnor6.0
Rnor_5.0199,690,498 - 9,690,692UniSTSRnor5.0
RGSC_v3.4199,749,153 - 9,749,347UniSTSRGSC3.4
Celera199,188,982 - 9,189,176UniSTS
Cytogenetic Map19p13UniSTS
MARC_16903-16904:1022861972:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2199,295,865 - 9,296,372 (+)MAPPERmRatBN7.2
Rnor_6.0199,708,842 - 9,709,348NCBIRnor6.0
Rnor_5.0199,694,025 - 9,694,531UniSTSRnor5.0
RGSC_v3.4199,752,680 - 9,753,186UniSTSRGSC3.4
Celera199,192,509 - 9,193,015UniSTS
Cytogenetic Map19p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC086325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016563   ⟹   ENSRNOP00000016563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl199,261,294 - 9,352,636 (+)Ensembl
mRatBN7.2 Ensembl199,255,194 - 9,346,574 (+)Ensembl
Rnor_6.0 Ensembl199,668,186 - 9,761,605 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105256   ⟹   ENSRNOP00000091388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl199,261,294 - 9,352,636 (+)Ensembl
mRatBN7.2 Ensembl199,255,194 - 9,346,574 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118032   ⟹   ENSRNOP00000090364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl199,261,299 - 9,352,359 (+)Ensembl
mRatBN7.2 Ensembl199,255,194 - 9,346,297 (+)Ensembl
RefSeq Acc Id: NM_001134840   ⟹   NP_001128312
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,294 - 9,352,636 (+)NCBI
mRatBN7.2199,255,194 - 9,346,574 (+)NCBI
Rnor_6.0199,668,186 - 9,761,605 (+)NCBI
Rnor_5.0199,652,472 - 9,746,683 (+)NCBI
RGSC_v3.4199,712,024 - 9,803,182 (+)RGD
Celera199,151,859 - 9,241,563 (+)RGD
Sequence:
RefSeq Acc Id: XM_039097544   ⟹   XP_038953472
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,290 - 9,352,623 (+)NCBI
mRatBN7.2199,255,190 - 9,346,574 (+)NCBI
RefSeq Acc Id: XM_039097547   ⟹   XP_038953475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,290 - 9,352,623 (+)NCBI
mRatBN7.2199,255,190 - 9,346,574 (+)NCBI
RefSeq Acc Id: XM_039097548   ⟹   XP_038953476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,290 - 9,352,623 (+)NCBI
mRatBN7.2199,255,190 - 9,346,574 (+)NCBI
RefSeq Acc Id: XM_039097549   ⟹   XP_038953477
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,290 - 9,352,623 (+)NCBI
mRatBN7.2199,255,190 - 9,346,574 (+)NCBI
RefSeq Acc Id: XM_063277843   ⟹   XP_063133913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,869 - 9,352,623 (+)NCBI
RefSeq Acc Id: XM_063277844   ⟹   XP_063133914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,869 - 9,352,623 (+)NCBI
RefSeq Acc Id: XM_063277845   ⟹   XP_063133915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,264,889 - 9,352,623 (+)NCBI
RefSeq Acc Id: XM_063277846   ⟹   XP_063133916
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,290 - 9,352,623 (+)NCBI
RefSeq Acc Id: XM_063277847   ⟹   XP_063133917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,290 - 9,352,623 (+)NCBI
RefSeq Acc Id: XM_063277848   ⟹   XP_063133918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,261,290 - 9,352,623 (+)NCBI
RefSeq Acc Id: NP_001128312   ⟸   NM_001134840
- UniProtKB: A6JXZ2 (UniProtKB/TrEMBL),   A0A8I6AG10 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016563   ⟸   ENSRNOT00000016563
RefSeq Acc Id: XP_038953472   ⟸   XM_039097544
- Peptide Label: isoform X1
- UniProtKB: G3V7M0 (UniProtKB/TrEMBL),   A0A8I6AG10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953477   ⟸   XM_039097549
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AG10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953476   ⟸   XM_039097548
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AG10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953475   ⟸   XM_039097547
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AG10 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000090364   ⟸   ENSRNOT00000118032
Ensembl Acc Id: ENSRNOP00000091388   ⟸   ENSRNOT00000105256
RefSeq Acc Id: XP_063133917   ⟸   XM_063277847
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AG10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133916   ⟸   XM_063277846
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AG10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133918   ⟸   XM_063277848
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AG10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133913   ⟸   XM_063277843
- Peptide Label: isoform X1
- UniProtKB: G3V7M0 (UniProtKB/TrEMBL),   A0A8I6AG10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133914   ⟸   XM_063277844
- Peptide Label: isoform X1
- UniProtKB: G3V7M0 (UniProtKB/TrEMBL),   A0A8I6AG10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133915   ⟸   XM_063277845
- Peptide Label: isoform X1
- UniProtKB: G3V7M0 (UniProtKB/TrEMBL),   A0A8I6AG10 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V7M0-F1-model_v2 AlphaFold G3V7M0 1-2376 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700922
Promoter ID:EPDNEW_R11446
Type:multiple initiation site
Name:Cnot1_1
Description:CCR4-NOT transcription complex, subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0199,668,219 - 9,668,279EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308009 AgrOrtholog
BioCyc Gene G2FUF-6550 BioCyc
Ensembl Genes ENSRNOG00000012271 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016563 ENTREZGENE
  ENSRNOT00000016563.7 UniProtKB/TrEMBL
  ENSRNOT00000105256.2 UniProtKB/TrEMBL
  ENSRNOT00000118032 ENTREZGENE
  ENSRNOT00000118032.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.180 UniProtKB/TrEMBL
  1.25.40.790 UniProtKB/TrEMBL
  1.25.40.800 UniProtKB/TrEMBL
  1.25.40.840 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7107420 IMAGE-MGC_LOAD
InterPro CCR4-Not_Not1_C UniProtKB/TrEMBL
  CCR4-Not_Not1su_DUF3819 UniProtKB/TrEMBL
  CNOT1 UniProtKB/TrEMBL
  CNOT1-like_NOT1_connector UniProtKB/TrEMBL
  CNOT1_1st UniProtKB/TrEMBL
  CNOT1_CAF1_bind UniProtKB/TrEMBL
  CNOT1_HEAT UniProtKB/TrEMBL
  CNOT1_TTP_bind UniProtKB/TrEMBL
  CNOT1_TTP_bind_sf UniProtKB/TrEMBL
KEGG Report rno:291841 UniProtKB/TrEMBL
MGC_CLONE MGC:105825 IMAGE-MGC_LOAD
NCBI Gene 291841 ENTREZGENE
PANTHER CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 UniProtKB/TrEMBL
  PTHR13162 UniProtKB/TrEMBL
Pfam CNOT1_1st UniProtKB/TrEMBL
  CNOT1_CAF1_bind UniProtKB/TrEMBL
  CNOT1_HEAT UniProtKB/TrEMBL
  CNOT1_TTP_bind UniProtKB/TrEMBL
  DUF3819 UniProtKB/TrEMBL
  Not1 UniProtKB/TrEMBL
  NOT1_connector UniProtKB/TrEMBL
PhenoGen Cnot1 PhenoGen
RatGTEx ENSRNOG00000012271 RatGTEx
UniProt A0A8I6ABN6_RAT UniProtKB/TrEMBL
  A0A8I6AG10 ENTREZGENE, UniProtKB/TrEMBL
  A6JXZ2 ENTREZGENE, UniProtKB/TrEMBL
  G3V7M0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-23 Cnot1  CCR4-NOT transcription complex, subunit 1  RGD1308009  similar to KIAA1007 protein; adrenal gland protein AD-005  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1308009  similar to KIAA1007 protein; adrenal gland protein AD-005  RGD1308009_predicted  similar to KIAA1007 protein; adrenal gland protein AD-005 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1308009_predicted  similar to KIAA1007 protein; adrenal gland protein AD-005 (predicted)  LOC291841_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC291841_predicted  similar to KIAA1007 protein; adrenal gland protein AD-005 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL