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Gene: Leng1 (leukocyte receptor cluster member 1) Rattus norvegicus

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Symbol:

Leng1

Name:

leukocyte receptor cluster member 1

RGD ID:

1307933

Description:

Orthologous to human LENG1 (leukocyte receptor cluster member 1); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

leukocyte receptor cluster (LRC) member 1; LOC292535

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LENG1 (leukocyte receptor cluster member 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Leng1 (leukocyte receptor cluster (LRC) member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Leng1 (leukocyte receptor cluster member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LENG1 (leukocyte receptor cluster member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LENG1 (leukocyte receptor cluster member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Leng1 (leukocyte receptor cluster member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LENG1 (leukocyte receptor cluster member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LENG1 (leukocyte receptor cluster member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Leng1 (leukocyte receptor cluster member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Leng1 (leukocyte receptor cluster member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	LENG1 (leukocyte receptor cluster member 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Leng1 (leukocyte receptor cluster (LRC) member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	leng1 (leukocyte receptor cluster (LRC) member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	leng1 (leukocyte receptor cluster (LRC) member 1)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12818	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y18H1A.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	leng1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	74,467,343 - 74,472,275 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	74,467,326 - 74,472,280 (+)	Ensembl				GRCr8
mRatBN7.2	1	65,551,983 - 65,556,915 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	65,551,983 - 65,556,915 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	71,000,107 - 71,005,039 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	79,423,081 - 79,428,013 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	72,750,226 - 72,755,158 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	64,126,882 - 64,131,814 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	64,126,882 - 64,131,814 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	63,119,164 - 63,124,096 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	63,864,911 - 63,869,843 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	63,277,025 - 63,281,957 (+)	NCBI		Celera
RGSC_v3.1	1	63,941,679 - 63,945,689 (+)	NCBI
Cytogenetic Map	1	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,6-trinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (EXP)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

caffeine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

cyclosporin A (ISO)

DDE (ISO)

dextran sulfate (ISO)

Dibutyl phosphate (ISO)

diethylstilbestrol (EXP)

disodium selenite (ISO)

fenvalerate (EXP)

folic acid (ISO)

FR900359 (ISO)

genistein (EXP)

Licochalcone B (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tetrachloroethene (ISO)

tetrachloromethane (EXP)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Leng1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	74,467,343 - 74,472,275 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	74,467,326 - 74,472,280 (+)	Ensembl				GRCr8
mRatBN7.2	1	65,551,983 - 65,556,915 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	65,551,983 - 65,556,915 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	71,000,107 - 71,005,039 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	79,423,081 - 79,428,013 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	72,750,226 - 72,755,158 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	64,126,882 - 64,131,814 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	64,126,882 - 64,131,814 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	63,119,164 - 63,124,096 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	63,864,911 - 63,869,843 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	63,277,025 - 63,281,957 (+)	NCBI		Celera
RGSC_v3.1	1	63,941,679 - 63,945,689 (+)	NCBI
Cytogenetic Map	1	q12	NCBI

LENG1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	54,155,161 - 54,159,721 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	54,155,161 - 54,159,721 (-)	Ensembl			hg38	GRCh38
GRCh37	19	54,658,899 - 54,663,459 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	59,351,189 - 59,355,258 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	59,351,192 - 59,355,258	NCBI
Celera	19	51,700,663 - 51,704,732 (-)	NCBI		Celera
Cytogenetic Map	19	q13.42	NCBI
HuRef	19	50,975,675 - 50,979,744 (-)	NCBI		HuRef
CHM1_1	19	54,660,658 - 54,664,727 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	57,235,427 - 57,239,987 (-)	NCBI		T2T-CHM13v2.0

Leng1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	3,663,106 - 3,668,839 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	3,663,097 - 3,668,839 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	3,660,107 - 3,665,840 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	3,660,098 - 3,665,840 (-)	Ensembl			mm10	GRCm38
MGSCv37	7	3,611,709 - 3,617,442 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	3,263,194 - 3,268,927 (-)	NCBI		MGSCv36	mm8
Celera	7	3,572,021 - 3,577,759 (-)	NCBI		Celera
Cytogenetic Map	7	A1	NCBI
cM Map	7	2.11	NCBI

Leng1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955604	106,796 - 109,485 (+)	Ensembl
ChiLan1.0	NW_004955604	106,509 - 109,564 (+)	NCBI	ChiLan1.0	ChiLan1.0

LENG1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	60,161,292 - 60,166,035 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	62,083,170 - 62,087,163 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	51,089,247 - 51,093,572 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	59,931,039 - 59,935,332 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	59,931,039 - 59,935,332 (-)	Ensembl			panPan2	panpan1.1

LENG1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	103,054,250 - 103,057,440 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	103,054,433 - 103,057,430 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	103,116,195 - 103,119,262 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	103,699,646 - 103,702,829 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	103,698,607 - 103,702,825 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	103,337,690 - 103,340,872 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	103,099,238 - 103,102,305 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	103,812,964 - 103,816,031 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Leng1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	2,662,564 - 2,666,634 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936994	267,334 - 275,317 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936994	271,167 - 275,367 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LENG1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	55,970,668 - 55,976,735 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	55,970,585 - 55,976,740 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	53,243,129 - 53,248,444 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LENG1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	46,832,615 - 46,840,896 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666073	26,923,300 - 26,927,241 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Leng1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	2,425,302 - 2,429,851 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624832	2,425,418 - 2,429,851 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Leng1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	178,250,251 - 178,255,396 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Leng1
36 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	466
Count of miRNA genes:	225
Interacting mature miRNAs:	263
Transcripts:	ENSRNOT00000017546
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	43457837	87558729	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	43457837	87558729	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	42122968	87122968	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	43457837	87558729	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	30708375	87558729	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	34565726	79565726	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	51909206	91302615	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	43509952	88509952	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	42122968	87122968	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat

Markers in Region

RH132704

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	74,465,865 - 74,466,707 (+)	Marker Load Pipeline
mRatBN7.2	1	65,550,505 - 65,551,347 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	64,125,405 - 64,126,246	NCBI	Rnor6.0
Rnor_5.0	1	63,117,687 - 63,118,528	UniSTS	Rnor5.0
RGSC_v3.4	1	63,863,434 - 63,864,275	UniSTS	RGSC3.4
Celera	1	63,275,548 - 63,276,389	UniSTS
RH 3.4 Map	1	741.5	UniSTS
Cytogenetic Map	1	q12	UniSTS

AW533911

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	65,556,680 - 65,556,886 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	64,131,580 - 64,131,785	NCBI	Rnor6.0
Rnor_5.0	1	63,123,862 - 63,124,067	UniSTS	Rnor5.0
RGSC_v3.4	1	63,869,609 - 63,869,814	UniSTS	RGSC3.4
Celera	1	63,281,723 - 63,281,928	UniSTS
RH 3.4 Map	1	740.9	UniSTS
Cytogenetic Map	1	q12	UniSTS

RH128211

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	65,554,869 - 65,555,078 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	64,129,769 - 64,129,977	NCBI	Rnor6.0
Rnor_5.0	1	63,122,051 - 63,122,259	UniSTS	Rnor5.0
RGSC_v3.4	1	63,867,798 - 63,868,006	UniSTS	RGSC3.4
Celera	1	63,279,912 - 63,280,120	UniSTS
RH 3.4 Map	1	741.0	UniSTS
Cytogenetic Map	1	q12	UniSTS

BF396308

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	65,557,031 - 65,557,260 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	64,131,931 - 64,132,159	NCBI	Rnor6.0
Rnor_5.0	1	63,124,213 - 63,124,441	UniSTS	Rnor5.0
RGSC_v3.4	1	63,869,960 - 63,870,188	UniSTS	RGSC3.4
Celera	1	63,282,074 - 63,282,302	UniSTS
RH 3.4 Map	1	742.69	UniSTS
Cytogenetic Map	1	q12	UniSTS

CNOT3_7840

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	65,555,822 - 65,556,304 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	64,130,722 - 64,131,203	NCBI	Rnor6.0
Rnor_5.0	1	63,123,004 - 63,123,485	UniSTS	Rnor5.0
RGSC_v3.4	1	63,868,751 - 63,869,232	UniSTS	RGSC3.4
Celera	1	63,280,865 - 63,281,346	UniSTS
Cytogenetic Map	1	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC103574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC126217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000091742 ⟹ ENSRNOP00000075238

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	74,467,326 - 74,472,280 (+)	Ensembl
mRatBN7.2 Ensembl	1	65,551,983 - 65,556,915 (+)	Ensembl
Rnor_6.0 Ensembl	1	64,126,882 - 64,131,814 (+)	Ensembl

RefSeq Acc Id:

NM_001106218 ⟹ NP_001099688

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	74,467,343 - 74,472,275 (+)	NCBI
mRatBN7.2	1	65,551,983 - 65,556,915 (+)	NCBI
Rnor_6.0	1	64,126,882 - 64,131,814 (+)	NCBI
Rnor_5.0	1	63,119,164 - 63,124,096 (+)	NCBI
RGSC_v3.4	1	63,864,911 - 63,869,843 (+)	RGD
Celera	1	63,277,025 - 63,281,957 (+)	RGD

Sequence:

show sequence

TGAAGAGTGGGCCTGACAGTCGGAGGTCGGCTTTGGAGCCATGAATATCTTACCCAAGAAGAGC
TGGCACGTCCGGAACAAGGACAATGTCGCTCGCGTGCGACGCGACGAGGCCCAGGCCCGGGAGG
AGGAGAAGGAGCGTGAGCGGAGGGTGCTGCTCGCTCAGCAAGAGGCCCGTACGGAATTCCTACG
GAAGAAAGCCAGGGGCCGAAACTCACTGCCCGAGCTGGAAGCAGCAGACCAGGGAGCTCCATGT
TCTGGCCCTGTGGACCTGTTTCGGGAGCTGCTGGAAGAAGGAAAAGGAGTGCCCAGAGGCAATA
AAGAGCATGAGGAAGAGAAACGACAGGAAAAAGAGAGACAAGAGAAAGCACTAGGTATTCTGAC
ATACTTGGGCCAAAGTGCAGCAGAGGCCCAAACTCAACCTCCCTGGTACCAGCTACCCCCAGGG
CAAAAAGGCTGCCCTCCAGGCCCAAGCCCAGATGAGAAGATCAAAAATCGACTGGACCCCTTGA
GGGAGATGCAGAAGCACCTGGGCAAGAAAAGGCACAGCAGCGAAAGCCATCCTTCCAGAGAGGA
ACGGCCTCCAAAACAACGGCCCAGAGAGCCACCTTCCCTAGAAAAGCTCCGTGCTGAGCGTCTT
CAGCGGGAAGCAGCTGAGAGAGCTCGAGCAGAGGCCCTGCTGGCCCGGGTACAAGGACAGGTAT
CCCAGCAAGGTCAGGTGGAAATGGAAGAGACAGATGAACGGAAGCGGCGATACAACTCCCAGTT
CAACCCCCAACTGGCTCGGCGACCCCGCCAGCAGAATCCAACTCCTCCCCACTGAACTCTTTTG
GGGGGATAGGGGAGGCTGCAGGTGCCAGCCGTCATATAAAACTATTTATTCATAAATATTTTCC
AAAATGAAAATAGGTTTACCAAAAAATGTCCCTCACTGGGGAGGGGAGGAGGGGGCAGCCCTTG
CCCCCAGGCCCCCAGGGTAGGGCAGAGAGGAAGAGAAAACTTCCCTATCCCTTCTCTGCTTCCT
GGGGCGGGAGGGTGTCCCATGGCCTTGGGCCTCCCCCAGTCTTCCAGGGCAGGGCCCTCACCTG
GGCAGGGGGATCAGCATGCGGGGGAGGGGGAGGGTAAAGGGGGCCGGTGTCACTGGAGGTCCCG
GTCCTCCAGGTAGCGATACTCAAAGGTGAAGCCTTCCTTCTTCCGCTGGCCCCACTTCTCGTAG
TCAAAGTAGATGTAGGTGCCCTGGCCGGGGAAGAAGGTGGTCAGTGAGTGGACGAAGAGGGGGG
CTGAGATCTGGGCCAGGCAGATGAACAAGAGGCAGTTGTCAGGGACATGGAGGTACCAAGCCAA
CTGTCCTACATGCTTGCACTGTCACACTCCACCCTCAGTGACCTTAAAAGTGAAGAAGGGGGCC
AAGCCTCGCCTTTTTGGGCCTGCAGGTACAAACATGAGGCCTAAGCTTATGTTAAGTGACAACT
GAAGAGTGGGCACCAACAGGTGGCCTACAATGCAACATATGCACCATAAACATCTAAGTGCTCT
GTGGAAATACACTACTTAATTCATTGTAACTGAGATTCTGAGGGATTCAATGCCCTGAGATAGT
TATGTCAAAGAACAAACCAGGGCAAGATAGGAAGGCTGAACTCAAGGTTGGAGAGCATACAGCA
AGAAAGCAGCTAGGTCAAGTGTCTGAAATGCTTCAAAGTGGTCAGGAAGAATATAGGGGACAGT
CCAGATTTCTCTAAGAATGGGAACCAGCTTGGAACCTGGAAGTGTAGGTGGGGAAAATATCTAT
GGGGAAAGCCACTGTGAAACACACCAACTGAAAGCAATAAAATTCATGACGCTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099688	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL84931	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000075238
	ENSRNOP00000075238.1

RefSeq Acc Id:

NP_001099688 ⟸ NM_001106218

- UniProtKB:

D3ZER8 (UniProtKB/TrEMBL), A6KS24 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNILPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARGRNSLPELE
AADQGAPCSGPVDLFRELLEEGKGVPRGNKEHEEEKRQEKERQEKALGILTYLGQSAAEAQTQP
PWYQLPPGQKGCPPGPSPDEKIKNRLDPLREMQKHLGKKRHSSESHPSREERPPKQRPREPPSL
EKLRAERLQREAAERARAEALLARVQGQVSQQGQVEMEETDERKRRYNSQFNPQLARRPRQQNP
TPPH

hide sequence

Ensembl Acc Id:

ENSRNOP00000075238 ⟸ ENSRNOT00000091742

Protein Domains

CBF1-interacting co-repressor CIR N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZER8-F1-model_v2	AlphaFold	D3ZER8	1-260	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689661

Promoter ID:

EPDNEW_R186

Type:

multiple initiation site

Name:

Leng1_1

Description:

leukocyte receptor cluster member 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	64,126,899 - 64,126,959	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307933	AgrOrtholog
BioCyc Gene	G2FUF-61039	BioCyc
Ensembl Genes	ENSRNOG00000061893	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000091742	ENTREZGENE
	ENSRNOT00000091742.3	UniProtKB/TrEMBL
InterPro	CIR_N_dom	UniProtKB/TrEMBL
	LENG1-like	UniProtKB/TrEMBL
KEGG Report	rno:292535	UniProtKB/TrEMBL
NCBI Gene	292535	ENTREZGENE
PANTHER	LEUKOCYTE RECEPTOR CLUSTER MEMBER 1	UniProtKB/TrEMBL
	PTHR22093	UniProtKB/TrEMBL
Pfam	Cir_N	UniProtKB/TrEMBL
PhenoGen	Leng1	PhenoGen
RatGTEx	ENSRNOG00000061893	RatGTEx
SMART	Cir_N	UniProtKB/TrEMBL
UniProt	A6KS24	ENTREZGENE, UniProtKB/TrEMBL
	D3ZER8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-08	Leng1	leukocyte receptor cluster member 1	Leng1	leukocyte receptor cluster (LRC) member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Leng1	leukocyte receptor cluster (LRC) member 1	Leng1_predicted	leukocyte receptor cluster (LRC) member 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Leng1_predicted	leukocyte receptor cluster (LRC) member 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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