Adamts6 (ADAM metallopeptidase with thrombospondin type 1 motif, 6) - Rat Genome Database

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Pathways
Gene: Adamts6 (ADAM metallopeptidase with thrombospondin type 1 motif, 6) Rattus norvegicus
Analyze
Symbol: Adamts6
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 6
RGD ID: 1307678
Description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization and proteolysis. Predicted to act upstream of or within circulatory system development and kidney development. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Orthologous to human ADAMTS6 (ADAM metallopeptidase with thrombospondin type 1 motif 6); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A disintegrin and metalloproteinase with thrombospondin motifs 6; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6; LOC361886
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8237,155,260 - 37,367,077 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl237,155,288 - 37,367,070 (+)EnsemblGRCr8
mRatBN7.2235,421,483 - 35,633,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl235,421,510 - 35,633,298 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx242,534,492 - 42,746,841 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0240,593,177 - 40,805,543 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0235,449,532 - 35,662,266 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0234,374,142 - 34,589,676 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl234,374,158 - 34,586,755 (+)Ensemblrn6Rnor6.0
Rnor_5.0253,495,958 - 53,716,434 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4235,213,712 - 35,434,336 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera231,397,794 - 31,599,803 (+)NCBICelera
RGSC_v3.1235,133,406 - 35,352,203 (+)NCBI
Cytogenetic Map2q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:25807483   PMID:30361391  


Genomics

Comparative Map Data
Adamts6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8237,155,260 - 37,367,077 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl237,155,288 - 37,367,070 (+)EnsemblGRCr8
mRatBN7.2235,421,483 - 35,633,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl235,421,510 - 35,633,298 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx242,534,492 - 42,746,841 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0240,593,177 - 40,805,543 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0235,449,532 - 35,662,266 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0234,374,142 - 34,589,676 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl234,374,158 - 34,586,755 (+)Ensemblrn6Rnor6.0
Rnor_5.0253,495,958 - 53,716,434 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4235,213,712 - 35,434,336 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera231,397,794 - 31,599,803 (+)NCBICelera
RGSC_v3.1235,133,406 - 35,352,203 (+)NCBI
Cytogenetic Map2q13NCBI
ADAMTS6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38565,148,738 - 65,481,920 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl565,148,738 - 65,481,920 (-)Ensemblhg38GRCh38
GRCh37564,444,565 - 64,777,747 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36564,480,319 - 64,813,460 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34564,480,321 - 64,530,348NCBI
Celera561,441,460 - 61,776,222 (-)NCBICelera
Cytogenetic Map5q12.3NCBI
HuRef561,399,229 - 61,733,640 (-)NCBIHuRef
CHM1_1564,444,425 - 64,777,370 (-)NCBICHM1_1
T2T-CHM13v2.0565,968,856 - 66,303,685 (-)NCBIT2T-CHM13v2.0
Adamts6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913104,423,026 - 104,633,203 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13104,424,343 - 104,633,203 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3813104,286,518 - 104,496,695 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13104,287,835 - 104,496,695 (+)Ensemblmm10GRCm38
MGSCv3713105,077,953 - 105,284,843 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3613105,408,255 - 105,615,145 (+)NCBIMGSCv36mm8
Celera13108,683,304 - 108,890,181 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1356.42NCBI
Adamts6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554463,620,795 - 3,902,829 (+)Ensembl
ChiLan1.0NW_0049554463,620,795 - 3,902,829 (+)NCBIChiLan1.0ChiLan1.0
ADAMTS6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2448,435,291 - 48,769,826 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1546,596,419 - 46,923,452 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0548,517,814 - 48,854,545 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1550,173,296 - 50,505,528 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl550,181,529 - 50,502,433 (+)EnsemblpanPan2panpan1.1
ADAMTS6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1250,955,180 - 51,249,075 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl250,955,481 - 51,236,421 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha247,908,675 - 48,192,053 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0251,443,822 - 51,727,266 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl251,443,823 - 51,735,601 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1248,498,253 - 48,787,512 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0249,293,388 - 49,576,663 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0250,181,510 - 50,468,796 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Adamts6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213194,739,311 - 195,028,741 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364803,675,805 - 3,965,210 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364803,798,044 - 3,965,203 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAMTS6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1643,702,521 - 44,019,704 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11643,702,519 - 44,010,820 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21646,987,181 - 47,283,577 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADAMTS6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1461,339,444 - 61,673,366 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660499,980,945 - 10,314,741 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adamts6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248154,427,371 - 4,725,031 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248154,427,297 - 4,727,991 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Adamts6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13192,863,348 - 193,081,168 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Adamts6
2078 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:54
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000016997, ENSRNOT00000072577
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2142977529Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
9590080Insglur4Insulin/glucose ratio QTL 428.70.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)2615276751152767Rat
1300160Hrtrt3Heart rate QTL 33.62heart pumping trait (VT:2000009)absolute change in heart rate (CMO:0000534)23561408353462005Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
731166Mamtr2Mammary tumor resistance QTL 20.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358154623581Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22888999173889991Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358144538110Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)2573632550736325Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)23326999678269996Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat

Markers in Region
RH142611  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2235,630,982 - 35,631,116 (+)MAPPERmRatBN7.2
Rnor_6.0234,587,358 - 34,587,491NCBIRnor6.0
Rnor_5.0253,714,116 - 53,714,249UniSTSRnor5.0
RGSC_v3.4235,432,437 - 35,432,570UniSTSRGSC3.4
Celera231,597,907 - 31,598,040UniSTS
RH 3.4 Map2155.7UniSTS
Cytogenetic Map2q13UniSTS
RH143095  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2235,509,264 - 35,509,559 (+)MAPPERmRatBN7.2
Rnor_6.0234,463,514 - 34,463,808NCBIRnor6.0
Rnor_5.0253,591,654 - 53,591,948UniSTSRnor5.0
RGSC_v3.4235,309,304 - 35,309,598UniSTSRGSC3.4
Celera231,475,974 - 31,476,268UniSTS
RH 3.4 Map2150.6UniSTS
Cytogenetic Map2q13UniSTS
BI301712  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2235,562,185 - 35,562,378 (+)MAPPERmRatBN7.2
Rnor_6.0234,518,552 - 34,518,744NCBIRnor6.0
Rnor_5.0253,645,227 - 53,645,419UniSTSRnor5.0
RGSC_v3.4235,363,101 - 35,363,293UniSTSRGSC3.4
Celera231,529,256 - 31,529,448UniSTS
RH 3.4 Map2155.5UniSTS
Cytogenetic Map2q13UniSTS
BM392312  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2235,622,363 - 35,622,528 (+)MAPPERmRatBN7.2
Rnor_6.0234,578,739 - 34,578,903NCBIRnor6.0
Rnor_5.0253,705,497 - 53,705,661UniSTSRnor5.0
RGSC_v3.4235,423,818 - 35,423,982UniSTSRGSC3.4
Celera231,589,288 - 31,589,452UniSTS
RH 3.4 Map2155.7UniSTS
Cytogenetic Map2q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 87 59 6 350 187 11 140 80 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005500311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN542748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016997   ⟹   ENSRNOP00000016997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl237,155,288 - 37,367,070 (+)Ensembl
mRatBN7.2 Ensembl235,421,510 - 35,633,298 (+)Ensembl
Rnor_6.0 Ensembl234,374,158 - 34,586,755 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000072577   ⟹   ENSRNOP00000064275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl234,546,988 - 34,586,755 (+)Ensembl
RefSeq Acc Id: NM_001108544   ⟹   NP_001102014
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,155,288 - 37,367,073 (+)NCBI
mRatBN7.2235,421,510 - 35,633,301 (+)NCBI
RefSeq Acc Id: XM_017591186   ⟹   XP_017446675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,183,676 - 37,367,077 (+)NCBI
mRatBN7.2235,449,909 - 35,633,305 (+)NCBI
Rnor_6.0234,403,071 - 34,589,676 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591187   ⟹   XP_017446676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,241,978 - 37,367,077 (+)NCBI
mRatBN7.2235,508,204 - 35,633,305 (+)NCBI
Rnor_6.0234,463,886 - 34,589,676 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591188   ⟹   XP_017446677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,255,056 - 37,367,077 (+)NCBI
mRatBN7.2235,521,282 - 35,633,305 (+)NCBI
Rnor_6.0234,476,116 - 34,589,676 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039102547   ⟹   XP_038958475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,155,260 - 37,345,642 (+)NCBI
mRatBN7.2235,421,483 - 35,611,875 (+)NCBI
RefSeq Acc Id: XM_039102548   ⟹   XP_038958476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,155,260 - 37,324,391 (+)NCBI
mRatBN7.2235,421,483 - 35,590,609 (+)NCBI
RefSeq Acc Id: XM_039102549   ⟹   XP_038958477
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,183,676 - 37,367,077 (+)NCBI
mRatBN7.2235,449,909 - 35,633,305 (+)NCBI
RefSeq Acc Id: XM_039102550   ⟹   XP_038958478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,183,758 - 37,367,077 (+)NCBI
mRatBN7.2235,449,982 - 35,633,305 (+)NCBI
RefSeq Acc Id: XM_039102551   ⟹   XP_038958479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,183,676 - 37,367,077 (+)NCBI
mRatBN7.2235,449,909 - 35,633,305 (+)NCBI
RefSeq Acc Id: XM_039102552   ⟹   XP_038958480
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,241,983 - 37,367,077 (+)NCBI
mRatBN7.2235,508,209 - 35,633,305 (+)NCBI
RefSeq Acc Id: XM_039102553   ⟹   XP_038958481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,155,260 - 37,308,841 (+)NCBI
mRatBN7.2235,421,483 - 35,575,064 (+)NCBI
RefSeq Acc Id: XM_063282029   ⟹   XP_063138099
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,215,447 - 37,367,077 (+)NCBI
RefSeq Acc Id: XR_005500311
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8237,155,260 - 37,336,708 (+)NCBI
mRatBN7.2235,421,483 - 35,602,936 (+)NCBI
RefSeq Acc Id: XP_017446675   ⟸   XM_017591186
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017446676   ⟸   XM_017591187
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017446677   ⟸   XM_017591188
- Peptide Label: isoform X8
- Sequence:
Ensembl Acc Id: ENSRNOP00000064275   ⟸   ENSRNOT00000072577
Ensembl Acc Id: ENSRNOP00000016997   ⟸   ENSRNOT00000016997
RefSeq Acc Id: XP_038958475   ⟸   XM_039102547
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038958476   ⟸   XM_039102548
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038958481   ⟸   XM_039102553
- Peptide Label: isoform X9
RefSeq Acc Id: NP_001102014   ⟸   NM_001108544
- UniProtKB: D4A065 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958477   ⟸   XM_039102549
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038958479   ⟸   XM_039102551
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038958478   ⟸   XM_039102550
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038958480   ⟸   XM_039102552
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063138099   ⟸   XM_063282029
- Peptide Label: isoform X6
Protein Domains
Peptidase M12B   PLAC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A065-F1-model_v2 AlphaFold D4A065 1-1117 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307678 AgrOrtholog
BioCyc Gene G2FUF-54551 BioCyc
Ensembl Genes ENSRNOG00000012655 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016997 ENTREZGENE
  ENSRNOT00000016997.9 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  2.60.120.830 UniProtKB/TrEMBL
  3.40.1620.60 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro ADAM_CR_2 UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  ADAMTS/ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_CR_3 UniProtKB/TrEMBL
  MetalloPept_cat_dom UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  Thrombospondin_1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene 361886 ENTREZGENE
PANTHER A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 6 UniProtKB/TrEMBL
  ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/TrEMBL
Pfam ADAM_CR_2 UniProtKB/TrEMBL
  ADAM_CR_3 UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
  TSP1_ADAMTS UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PhenoGen Adamts6 PhenoGen
PRINTS ADAMTSFAMILY UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012655 RatGTEx
SMART TSP1 UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
UniProt D4A065 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-18 Adamts6  ADAM metallopeptidase with thrombospondin type 1 motif, 6  Adamts6  a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-10 Adamts6  a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6  Adamts6  a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Adamts6  a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6  Adamts6_predicted  a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Adamts6_predicted  a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED