Arel1 (apoptosis resistant E3 ubiquitin protein ligase 1) - Rat Genome Database

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Pathways
Gene: Arel1 (apoptosis resistant E3 ubiquitin protein ligase 1) Rattus norvegicus
Analyze
Symbol: Arel1
Name: apoptosis resistant E3 ubiquitin protein ligase 1
RGD ID: 1307597
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be active in cytosol. Orthologous to human AREL1 (apoptosis resistant E3 ubiquitin protein ligase 1); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; fipronil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: apoptosis-resistant E3 ubiquitin protein ligase 1; hypothetical protein LOC299197; LOC299197; RGD1307597; similar to mKIAA0317 protein; uncharacterized protein LOC299197
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86110,296,072 - 110,348,751 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6110,296,072 - 110,320,832 (-)EnsemblGRCr8
mRatBN7.26104,560,556 - 104,617,712 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6104,564,986 - 104,617,628 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6104,734,704 - 104,763,166 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06105,033,876 - 105,062,340 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06104,403,226 - 104,431,688 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06108,630,790 - 108,796,096 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6108,635,220 - 108,796,124 (-)Ensemblrn6Rnor6.0
Rnor_5.06116,882,562 - 116,922,259 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46108,963,520 - 108,992,271 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6102,388,676 - 102,416,454 (-)NCBICelera
RGSC_v3.16108,969,035 - 108,999,416 (-)NCBI
Cytogenetic Map6q31NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
cytosol  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:23479728   PMID:31578312  


Genomics

Comparative Map Data
Arel1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86110,296,072 - 110,348,751 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6110,296,072 - 110,320,832 (-)EnsemblGRCr8
mRatBN7.26104,560,556 - 104,617,712 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6104,564,986 - 104,617,628 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6104,734,704 - 104,763,166 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06105,033,876 - 105,062,340 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06104,403,226 - 104,431,688 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06108,630,790 - 108,796,096 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6108,635,220 - 108,796,124 (-)Ensemblrn6Rnor6.0
Rnor_5.06116,882,562 - 116,922,259 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46108,963,520 - 108,992,271 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6102,388,676 - 102,416,454 (-)NCBICelera
RGSC_v3.16108,969,035 - 108,999,416 (-)NCBI
Cytogenetic Map6q31NCBI
AREL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381474,661,256 - 74,713,080 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1474,653,437 - 74,713,117 (-)Ensemblhg38GRCh38
GRCh371475,127,959 - 75,179,783 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361474,197,708 - 74,249,560 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341474,189,634 - 74,249,560NCBI
Celera1455,166,339 - 55,218,171 (-)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1455,296,047 - 55,347,878 (-)NCBIHuRef
CHM1_11475,067,096 - 75,118,955 (-)NCBICHM1_1
T2T-CHM13v2.01468,870,372 - 68,922,179 (-)NCBIT2T-CHM13v2.0
Arel1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,964,914 - 85,017,674 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,964,922 - 85,017,674 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381284,918,140 - 84,970,878 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,918,148 - 84,970,900 (-)Ensemblmm10GRCm38
MGSCv371286,259,098 - 86,311,836 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361285,807,494 - 85,840,311 (-)NCBIMGSCv36mm8
Celera1286,375,198 - 86,428,152 (-)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.46NCBI
Arel1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955523818,535 - 874,189 (+)Ensembl
ChiLan1.0NW_004955523818,535 - 874,189 (+)NCBIChiLan1.0ChiLan1.0
AREL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21575,744,134 - 75,795,871 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11474,960,644 - 75,012,411 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01455,213,600 - 55,265,198 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11474,060,648 - 74,112,165 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1474,060,653 - 74,112,165 (-)EnsemblpanPan2panpan1.1
AREL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1847,798,946 - 47,819,364 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl847,801,895 - 47,819,318 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha847,482,601 - 47,525,768 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0848,025,898 - 48,069,077 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl848,026,855 - 48,069,067 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1847,696,920 - 47,740,078 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0847,718,274 - 47,761,437 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0848,116,253 - 48,159,412 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arel1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,186,925 - 28,233,947 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364883,835,075 - 3,876,403 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364883,835,021 - 3,882,055 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AREL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl797,875,220 - 97,940,876 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1797,893,182 - 97,940,932 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27103,736,289 - 103,783,732 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AREL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12451,877,074 - 51,928,042 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605340,104,994 - 40,156,793 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arel1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473426,960,548 - 27,009,771 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473426,960,511 - 27,014,369 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Arel1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1799,024,284 - 99,049,667 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Arel1
303 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:371
Count of miRNA genes:202
Interacting mature miRNAs:270
Transcripts:ENSRNOT00000006240
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)699437079125323237Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)699708426112483760Rat

Markers in Region
RH133218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21153,060,525 - 153,060,718 (+)MAPPERmRatBN7.2
mRatBN7.26104,565,539 - 104,565,732 (+)MAPPERmRatBN7.2
Rnor_6.01163,720,205 - 163,720,397NCBIRnor6.0
Rnor_6.06108,635,774 - 108,635,966NCBIRnor6.0
Rnor_5.06116,917,083 - 116,917,275UniSTSRnor5.0
Rnor_5.01169,923,229 - 169,923,421UniSTSRnor5.0
RGSC_v3.41156,039,820 - 156,040,012UniSTSRGSC3.4
RGSC_v3.46108,964,074 - 108,964,266UniSTSRGSC3.4
Celera6102,389,230 - 102,389,422UniSTS
Celera1151,148,609 - 151,148,801UniSTS
Cytogenetic Map6q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC113727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000006240   ⟹   ENSRNOP00000006240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6110,296,072 - 110,320,832 (-)Ensembl
mRatBN7.2 Ensembl6104,564,986 - 104,617,628 (-)Ensembl
Rnor_6.0 Ensembl6108,635,220 - 108,660,063 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086545   ⟹   ENSRNOP00000074719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6108,637,369 - 108,796,124 (-)Ensembl
RefSeq Acc Id: NM_001106744   ⟹   NP_001100214
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,072 - 110,324,562 (-)NCBI
mRatBN7.26104,564,986 - 104,593,476 (-)NCBI
Rnor_6.06108,635,220 - 108,663,764 (-)NCBI
Rnor_5.06116,882,562 - 116,922,259 (+)NCBI
RGSC_v3.46108,963,520 - 108,992,271 (-)RGD
Celera6102,388,676 - 102,416,454 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240333   ⟹   XP_006240395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,331,262 (-)NCBI
mRatBN7.26104,560,556 - 104,600,178 (-)NCBI
Rnor_6.06108,630,790 - 108,670,464 (-)NCBI
Rnor_5.06116,882,562 - 116,922,259 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764754   ⟹   XP_008762976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,348,751 (-)NCBI
mRatBN7.26104,560,556 - 104,617,711 (-)NCBI
Rnor_6.06108,630,790 - 108,796,096 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594097   ⟹   XP_017449586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,348,751 (-)NCBI
mRatBN7.26104,560,556 - 104,617,711 (-)NCBI
Rnor_6.06108,630,790 - 108,796,096 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112037   ⟹   XP_038967965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,348,747 (-)NCBI
mRatBN7.26104,560,556 - 104,617,711 (-)NCBI
RefSeq Acc Id: XM_039112038   ⟹   XP_038967966
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,348,747 (-)NCBI
mRatBN7.26104,560,556 - 104,617,711 (-)NCBI
RefSeq Acc Id: XM_039112039   ⟹   XP_038967967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,341,738 (-)NCBI
mRatBN7.26104,560,556 - 104,610,643 (-)NCBI
RefSeq Acc Id: XM_063261740   ⟹   XP_063117810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,348,679 (-)NCBI
RefSeq Acc Id: XM_063261742   ⟹   XP_063117812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,348,749 (-)NCBI
RefSeq Acc Id: XM_063261743   ⟹   XP_063117813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,348,751 (-)NCBI
RefSeq Acc Id: XM_063261744   ⟹   XP_063117814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,348,679 (-)NCBI
RefSeq Acc Id: XM_063261745   ⟹   XP_063117815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,331,262 (-)NCBI
RefSeq Acc Id: XM_063261746   ⟹   XP_063117816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,296,073 - 110,325,371 (-)NCBI
RefSeq Acc Id: XR_010052071
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86110,304,605 - 110,348,751 (-)NCBI
RefSeq Acc Id: NP_001100214   ⟸   NM_001106744
- UniProtKB: D3ZVC4 (UniProtKB/TrEMBL),   A6JDZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240395   ⟸   XM_006240333
- Peptide Label: isoform X1
- UniProtKB: D3ZVC4 (UniProtKB/TrEMBL),   A6JDZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762976   ⟸   XM_008764754
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017449586   ⟸   XM_017594097
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000006240   ⟸   ENSRNOT00000006240
Ensembl Acc Id: ENSRNOP00000074719   ⟸   ENSRNOT00000086545
RefSeq Acc Id: XP_038967966   ⟸   XM_039112038
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038967965   ⟸   XM_039112037
- Peptide Label: isoform X1
- UniProtKB: D3ZVC4 (UniProtKB/TrEMBL),   A6JDZ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967967   ⟸   XM_039112039
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063117813   ⟸   XM_063261743
- Peptide Label: isoform X1
- UniProtKB: A6JDZ1 (UniProtKB/TrEMBL),   D3ZVC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117812   ⟸   XM_063261742
- Peptide Label: isoform X1
- UniProtKB: A6JDZ1 (UniProtKB/TrEMBL),   D3ZVC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117814   ⟸   XM_063261744
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063117810   ⟸   XM_063261740
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063117815   ⟸   XM_063261745
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063117816   ⟸   XM_063261746
- Peptide Label: isoform X2
Protein Domains
HECT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZVC4-F1-model_v2 AlphaFold D3ZVC4 1-823 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694743
Promoter ID:EPDNEW_R5257
Type:initiation region
Name:Arel1_1
Description:apoptosis resistant E3 ubiquitin protein ligase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06108,796,090 - 108,796,150EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307597 AgrOrtholog
BioCyc Gene G2FUF-36805 BioCyc
Ensembl Genes ENSRNOG00000004382 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006240 ENTREZGENE
  ENSRNOT00000006240.8 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domain UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domain UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domains UniProtKB/TrEMBL
InterPro E3_ubiq-protein_ligase UniProtKB/TrEMBL
  Filamin/ABP280_repeat-like UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
  Hect_E3_ubiquitin_ligase UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
KEGG Report rno:299197 UniProtKB/TrEMBL
NCBI Gene 299197 ENTREZGENE
PANTHER APOPTOSIS-RESISTANT E3 UBIQUITIN PROTEIN LIGASE 1 UniProtKB/TrEMBL
  HECT DOMAIN UBIQUITIN-PROTEIN LIGASE UniProtKB/TrEMBL
Pfam Filamin UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
PhenoGen Arel1 PhenoGen
PROSITE FILAMIN_REPEAT UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004382 RatGTEx
SMART HECTc UniProtKB/TrEMBL
Superfamily-SCOP HECT UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
UniProt A6JDZ1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVC4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-04-25 Arel1  apoptosis resistant E3 ubiquitin protein ligase 1  RGD1307597  similar to mKIAA0317 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1307597  similar to mKIAA0317 protein   RGD1307597_predicted  similar to mKIAA0317 protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1307597_predicted  similar to mKIAA0317 protein (predicted)  LOC299197_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC299197_predicted  similar to mKIAA0317 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL