Ddx21 (DExD-box helicase 21) - Rat Genome Database

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Gene: Ddx21 (DExD-box helicase 21) Rattus norvegicus
Analyze
Symbol: Ddx21
Name: DExD-box helicase 21
RGD ID: 1307306
Description: Predicted to enable RNA binding activity; RNA helicase activity; and identical protein binding activity. Predicted to be involved in several processes, including R-loop processing; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of macromolecule biosynthetic process. Predicted to act upstream of or within response to exogenous dsRNA and response to virus. Predicted to be located in chromosome; cytosol; and nucleoplasm. Predicted to be part of B-WICH complex. Predicted to be active in nucleolus. Orthologous to human DDX21 (DExD-box helicase 21); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ddx21a; Ddx21b; DEAD (Asp-Glu-Ala-Asp) box helicase 21; DEAD (Asp-Glu-Ala-Asp) box polypeptide 21; DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a; DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b; DEAD box protein 21; DEAD-box helicase 21; gu-alpha; LOC317399; LOC361847; MGC112658; MGC124980; nucleolar RNA helicase 2; nucleolar RNA helicase Gu; nucleolar RNA helicase II; RH II/Gu
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Ddx21-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82031,077,044 - 31,097,238 (-)NCBIGRCr8
mRatBN7.22030,534,319 - 30,554,513 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2030,534,319 - 30,554,543 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2031,545,279 - 31,565,477 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,936,186 - 30,956,386 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02031,673,000 - 31,693,177 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02032,213,147 - 32,232,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2032,213,148 - 32,232,632 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02033,997,711 - 34,017,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42029,838,671 - 29,860,514 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2031,953,138 - 31,973,565 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-nitrofluorene  (EXP)
3',5'-cyclic UMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cordycepin  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
enzyme inhibitor  (ISO)
flutamide  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (ISO)
gentamycin  (EXP)
ivermectin  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
methamphetamine  (EXP)
methapyrilene  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
ochratoxin A  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
parathion  (ISO)
pentachlorophenol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP,ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (ISO)
propiconazole  (ISO)
raloxifene  (ISO)
resveratrol  (EXP,ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
B-WICH complex  (ISO)
chromosome  (ISO)
cytosol  (ISO,ISS)
mitochondrion  (IEA)
nucleolus  (IBA,ISO,ISS)
nucleoplasm  (ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1639225   PMID:9461305   PMID:12477932   PMID:15489334   PMID:16210410   PMID:19946888   PMID:21703541   PMID:22658674   PMID:22681889   PMID:25470060   PMID:28431233   PMID:28790157  
PMID:33450132  


Genomics

Comparative Map Data
Ddx21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82031,077,044 - 31,097,238 (-)NCBIGRCr8
mRatBN7.22030,534,319 - 30,554,513 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2030,534,319 - 30,554,543 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2031,545,279 - 31,565,477 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,936,186 - 30,956,386 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02031,673,000 - 31,693,177 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02032,213,147 - 32,232,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2032,213,148 - 32,232,632 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02033,997,711 - 34,017,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42029,838,671 - 29,860,514 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2031,953,138 - 31,973,565 (-)NCBICelera
Cytogenetic Map20q11NCBI
DDX21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381068,956,170 - 68,985,068 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1068,956,135 - 68,985,068 (+)EnsemblGRCh38hg38GRCh38
GRCh371070,715,926 - 70,744,824 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361070,385,898 - 70,414,285 (+)NCBINCBI36Build 36hg18NCBI36
Build 341070,385,897 - 70,414,285NCBI
Celera1063,991,762 - 64,020,150 (+)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1064,717,792 - 64,746,685 (+)NCBIHuRef
CHM1_11070,997,606 - 71,026,553 (+)NCBICHM1_1
T2T-CHM13v2.01069,825,602 - 69,854,499 (+)NCBIT2T-CHM13v2.0
Ddx21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391062,416,026 - 62,438,077 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1062,416,030 - 62,438,060 (-)EnsemblGRCm39 Ensembl
GRCm381062,580,247 - 62,602,298 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1062,580,251 - 62,602,281 (-)EnsemblGRCm38mm10GRCm38
MGSCv371062,042,995 - 62,065,046 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361061,975,604 - 61,997,655 (-)NCBIMGSCv36mm8
Celera1063,683,725 - 63,705,771 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.43NCBI
Ddx21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543722,050,937 - 22,071,118 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543722,050,029 - 22,071,213 (-)NCBIChiLan1.0ChiLan1.0
DDX21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2881,102,441 - 81,131,439 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11081,098,619 - 81,136,760 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01065,423,319 - 65,452,266 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11067,956,857 - 67,985,867 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1067,956,857 - 67,985,867 (+)Ensemblpanpan1.1panPan2
DDX21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1420,109,719 - 20,134,586 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl420,109,778 - 20,132,338 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha420,240,134 - 20,264,990 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0420,381,832 - 20,407,325 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl420,381,870 - 20,407,323 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1420,282,539 - 20,307,462 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0420,485,654 - 20,510,665 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0420,828,776 - 20,854,073 (+)NCBIUU_Cfam_GSD_1.0
Ddx21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721360,933,799 - 60,956,220 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365219,429,015 - 9,448,890 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365219,426,544 - 9,448,973 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1472,039,982 - 72,063,773 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11472,039,985 - 72,063,778 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21478,054,874 - 78,078,395 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1962,339,614 - 62,370,032 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604823,081,720 - 23,112,357 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247543,179,662 - 3,203,536 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247543,180,501 - 3,203,449 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ddx21
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:901
Count of miRNA genes:320
Interacting mature miRNAs:429
Transcripts:ENSRNOT00000068184
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202924438854435887Rat

Markers in Region
BI302095  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22030,554,669 - 30,554,822 (+)MAPPERmRatBN7.2
Rnor_6.02032,232,789 - 32,232,941NCBIRnor6.0
Rnor_5.02034,017,353 - 34,017,505UniSTSRnor5.0
RGSC_v3.42029,860,671 - 29,860,823UniSTSRGSC3.4
Celera2031,973,722 - 31,973,874UniSTS
RH 3.4 Map20308.38UniSTS
Cytogenetic Map20q11UniSTS
RH129516  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map20q11UniSTS
RH133206  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22030,535,678 - 30,535,859 (+)MAPPERmRatBN7.2
mRatBN7.2X18,566,044 - 18,566,225 (+)MAPPERmRatBN7.2
Rnor_6.0X19,383,535 - 19,383,715NCBIRnor6.0
Rnor_6.02032,214,507 - 32,214,687NCBIRnor6.0
Rnor_5.02033,999,071 - 33,999,251UniSTSRnor5.0
Rnor_5.0X20,150,411 - 20,150,591UniSTSRnor5.0
RGSC_v3.4X38,742,330 - 38,742,510UniSTSRGSC3.4
RGSC_v3.42029,840,031 - 29,840,211UniSTSRGSC3.4
Celera2031,954,498 - 31,954,678UniSTS
CeleraX18,831,612 - 18,831,792UniSTS
Cytogenetic Map20q11UniSTS
RH144150  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22030,547,722 - 30,547,884 (+)MAPPERmRatBN7.2
Rnor_6.02032,225,948 - 32,226,109NCBIRnor6.0
Rnor_5.02034,010,512 - 34,010,673UniSTSRnor5.0
RGSC_v3.42029,852,037 - 29,852,198UniSTSRGSC3.4
Celera2031,966,539 - 31,966,700UniSTS
RH 3.4 Map20308.36UniSTS
Cytogenetic Map20q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 40 55 39 19 39 8 10 74 35 36 11 8
Low 3 2 2 2 1 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000068184   ⟹   ENSRNOP00000063494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2030,534,319 - 30,554,543 (-)Ensembl
Rnor_6.0 Ensembl2032,213,148 - 32,232,632 (-)Ensembl
RefSeq Acc Id: NM_001037201   ⟹   NP_001032278
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82031,077,044 - 31,097,238 (-)NCBI
mRatBN7.22030,534,319 - 30,554,513 (-)NCBI
Rnor_6.02032,213,147 - 32,232,632 (-)NCBI
Rnor_5.02033,997,711 - 34,017,196 (-)NCBI
RGSC_v3.42029,838,671 - 29,860,514 (-)RGD
Celera2031,953,138 - 31,973,565 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001032278 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI05879 (Get FASTA)   NCBI Sequence Viewer  
  EDL92965 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063494
  ENSRNOP00000063494.1
  ENSRNOP00055020554
  ENSRNOP00060009446
  ENSRNOP00065003392
GenBank Protein Q3B8Q1 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001032278   ⟸   NM_001037201
- UniProtKB: Q3B8Q1 (UniProtKB/Swiss-Prot),   A6K457 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063494   ⟸   ENSRNOT00000068184
Protein Domains
Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3B8Q1-F1-model_v2 AlphaFold Q3B8Q1 1-782 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701616
Promoter ID:EPDNEW_R12140
Type:multiple initiation site
Name:Ddx21_1
Description:DExD-box helicase 21
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02032,232,644 - 32,232,704EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307306 AgrOrtholog
BioCyc Gene G2FUF-3684 BioCyc
Ensembl Genes ENSRNOG00000043099 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055014660 UniProtKB/Swiss-Prot
  ENSRNOG00060007562 UniProtKB/Swiss-Prot
  ENSRNOG00065003346 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000068184 ENTREZGENE
  ENSRNOT00000068184.2 UniProtKB/Swiss-Prot
  ENSRNOT00055025138 UniProtKB/Swiss-Prot
  ENSRNOT00060012476 UniProtKB/Swiss-Prot
  ENSRNOT00065004766 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.2280 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7126328 IMAGE-MGC_LOAD
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GUCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:317399 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:124980 IMAGE-MGC_LOAD
NCBI Gene 317399 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DEAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DEAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GUCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ddx21 PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Q_MOTIF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000043099 RatGTEx
  ENSRNOG00055014660 RatGTEx
  ENSRNOG00060007562 RatGTEx
  ENSRNOG00065003346 RatGTEx
SMART DEXDc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELICc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
  RNA-binding domain, RBD UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot
  SSF54928 UniProtKB/Swiss-Prot
UniProt A6K457 ENTREZGENE, UniProtKB/TrEMBL
  DDX21_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-05 Ddx21  DExD-box helicase 21  Ddx21  DEAD-box helicase 21  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-13 Ddx21  DEAD-box helicase 21  Ddx21  DEAD (Asp-Glu-Ala-Asp) box helicase 21  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-04 Ddx21  DEAD (Asp-Glu-Ala-Asp) box helicase 21  Ddx21b  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b  Data merged from RGD:1304998 737654 APPROVED
2012-07-16 Ddx21  DEAD (Asp-Glu-Ala-Asp) box helicase 21  Ddx21  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Ddx21  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21  Ddx21a  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ddx21b  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b  Ddx21b_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b (predicted)  Symbol and Name updated 1559027 APPROVED
2005-12-06 Ddx21a  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a  Ddx21a_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ddx21a_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a (predicted)      Symbol and Name status set to approved 70820 APPROVED
2005-01-12 Ddx21b_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b (predicted)      Symbol and Name status set to approved 70820 APPROVED